Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease

Authors: Ann-Christin Gnirck, Marie-Sophie Philipp, Alex Waterhölter, Malte Wunderlich, Nikhat Shaikh, Virginia Adamiak, Lena Henneken, Tobias Kautz, Tingting Xiong, Daniela Klaus, Pascal Tomczyk, Mohamad M. Al-Bahra, Dirk Menche, Mark Walkenhorst, Olivier Lantz, Anne Willing, Manuel A. Friese, Tobias B. Huber, Christian F. Krebs, Ulf Panzer, Christian Kurts, Jan-Eric Turner

Source: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ea197fd8a59e40e69a85f91fdcdab807

Multidisciplinary recommendations for the management of CAR-T recipients in the post-COVID-19 pandemic era

Authors: Tingting Zhang, Weiwei Tian, Shuang Wei, Xinyi Lu, Jing An, Shaolong He, Jie Zhao, Zhilin Gao, Li Li, Ke Lian, Qiang Zhou, Huilai Zhang, Liang Wang, Liping Su, Huicong Kang, Ting Niu, Ailin Zhao, Jing Pan, Qingqing Cai, Zhenshu Xu, Wenming Chen, Hongmei Jing, Peng Li, Wanhong Zhao, Yang Cao, Jianqing Mi, Tao Chen, Yuan Chen, Ping Zou, Veronika Lukacs-Kornek, Christian Kurts, Jian Li, Xiansheng Liu, Qi Mei, Yicheng Zhang, Jia Wei

Source: Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-17 (2023)

Subject Terms: SARS-CoV-2, COVID-19, CAR T-cell, Hematological malignancies, Treatment, Recommendations, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3619

Access URL: https://doaj.org/article/317083c379354394bdbd8c7877d9e996

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

Authors: Annkristin Heine, Niels A. W. Lemmermann, Chrystel Flores, Janine Becker-Gotot, Natalio Garbi, Peter Brossart, Christian Kurts

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: chemokines, CTL induction, post-exposure vaccination, murine cytomegalovirus, viral infection, NKT cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1338499/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/051e31edb5824e1484a74bf513adbdb8

Differential early diagnosis of benign versus malignant lung cancer using systematic pathway flux analysis of peripheral blood leukocytes

Authors: Jian Li, Xiaoyu Li, Ming Li, Hong Qiu, Christian Saad, Bo Zhao, Fan Li, Xiaowei Wu, Dong Kuang, Fengjuan Tang, Yaobing Chen, Hongge Shu, Jing Zhang, Qiuxia Wang, He Huang, Shankang Qi, Changkun Ye, Amy Bryant, Xianglin Yuan, Christian Kurts, Guangyuan Hu, Weiting Cheng, Qi Mei

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a3efc8e3513544b98aa4f210f115aad6

Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell immunoprofiling

Authors: Felix Schreibing, Monica T. Hannani, Hyojin Kim, James S. Nagai, Fabio Ticconi, Eleanor Fewings, Tore Bleckwehl, Matthias Begemann, Natalia Torow, Christoph Kuppe, Ingo Kurth, Jennifer Kranz, Dario Frank, Teresa M. Anslinger, Patrick Ziegler, Thomas Kraus, Jürgen Enczmann, Vera Balz, Frank Windhofer, Paul Balfanz, Christian Kurts, Gernot Marx, Nikolaus Marx, Michael Dreher, Rebekka K. Schneider, Julio Saez-Rodriguez, Ivan Costa, Sikander Hayat, Rafael Kramann

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: SARS-CoV-2, scRNA-seq, scTCR-seq, immunoprofiling, CD8+ T cells, FCGR3A, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1066176/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/cce264ecd7e04d4b9565ee6ebba1a40b

Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs

Authors: Janine Becker-Gotot, Mirjam Meissner, Vadim Kotov, Blanca Jurado-Mestre, Andrea Maione, Andreas Pannek, Thilo Albert, Chrystel Flores, Frank A. Schildberg, Paul A. Gleeson, Birgit M. Reipert, Johannes Oldenburg, Christian Kurts

Source: The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)

Subject Terms: Hematology, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/a91c4628ebc24941b2a4147590a1116b

Development and validation of prognostic model for predicting mortality of COVID-19 patients in Wuhan, China

Authors: Qi Mei, Amanda Y. Wang, Amy Bryant, Yang Yang, Ming Li, Fei Wang, Jia Wei Zhao, Ke Ma, Liang Wu, Huawen Chen, Jinlong Luo, Shangming Du, Kathrin Halfter, Yong Li, Christian Kurts, Guangyuan Hu, Xianglin Yuan, Jian Li

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0f82cb164d1f40f58fc2ea68383a9376

Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study

Authors: Yang Yang, Junping Yin, Jian Li, Bo Liu, Ming Li, Qiao Huang, Xianglin Yuan, Christian Kurts, Guangyuan Hu, Qi Mei, Xi Tang, Alexander Böhner, Amy Bryant

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/3/e004157.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/bf192d1bbf924353bb6a719c5ced7814

New Aspects of Kidney Fibrosis–From Mechanisms of Injury to Modulation of Disease

Authors: Marcus J. Moeller, Rafael Kramann, Twan Lammers, Bernd Hoppe, Eicke Latz, Isis Ludwig-Portugall, Peter Boor, Jürgen Floege, Christian Kurts, Ralf Weiskirchen, Tammo Ostendorf

Source: Frontiers in Medicine, Vol 8 (2022)

Subject Terms: renal fibrosis, myofibroblast, parietal epithelial cell, inflammasome, crystals, lupus erythematodes, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.814497/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/0f87e0335b7f4b0fa927f1acb1778c28

Health Issues and Immunological Assessment Related to Wuhan's COVID-19 Survivors: A Multicenter Follow-Up Study

Authors: Qi Mei, Fei Wang, Yang Yang, Guangyuan Hu, Suihuai Guo, Qing Zhang, Amy Bryant, Lingjie Zhang, Christian Kurts, Li Wei, Xianglin Yuan, Jian Li

Source: Frontiers in Medicine, Vol 8 (2021)

Subject Terms: post-COVID-19, SARS-CoV-2, mortality, hospital discharge, post-COVID-19 sequela, physical and psychological symptoms, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.617689/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/bb8a00371bca43b8bb95e24242ebdfa1

CX3CR1 is a prerequisite for the development of cardiac hypertrophy and left ventricular dysfunction in mice upon transverse aortic constriction.

Authors: Christina Katharina Weisheit, Jan Lukas Kleiner, Maria Belen Rodrigo, Sven Thomas Niepmann, Sebastian Zimmer, Georg Daniel Duerr, Mark Coburn, Christian Kurts, Stilla Frede, Lars Eichhorn

Source: PLoS ONE, Vol 16, Iss 1, p e0243788 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/5f0ae1753f5843dda6e5478f6e8e9d9d

Survival Factors and Metabolic Pathogenesis in Elderly Patients (≥65) With COVID-19: A Multi-Center Study

Authors: Qi Mei, Amanda Y. Wang, Amy Bryant, Yang Yang, Ming Li, Fei Wang, Shangming Du, Christian Kurts, Patrick Wu, Ke Ma, Liang Wu, Huawen Chen, Jinlong Luo, Yong Li, Guangyuan Hu, Xianglin Yuan, Jian Li

Source: Frontiers in Medicine, Vol 7 (2021)

Subject Terms: clinical stratification, elderly patients, mortality, prognostic factors, COVID-19, metabolic pathogenesis, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2020.595503/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/a7d02fcbf134477e8a9a7daf8ddc1ab3

Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells

Authors: Marc Rosenbaum, Andreas Gewies, Konstanze Pechloff, Christoph Heuser, Thomas Engleitner, Torben Gehring, Lara Hartjes, Sabrina Krebs, Daniel Krappmann, Mark Kriegsmann, Wilko Weichert, Roland Rad, Christian Kurts, Jürgen Ruland

Source: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/745f4f6f20b44529be4f9c3e0da19c9e

NCX1 represents an ionic Na+ sensing mechanism in macrophages.

Authors: Patrick Neubert, Arne Homann, David Wendelborn, Anna-Lorena Bär, Luka Krampert, Maximilian Trum, Agnes Schröder, Stefan Ebner, Andrea Weichselbaum, Valentin Schatz, Peter Linz, Roland Veelken, Jonas Schulte-Schrepping, Anna C Aschenbrenner, Thomas Quast, Christian Kurts, Sabrina Geisberger, Karl Kunzelmann, Karin Hammer, Katrina J Binger, Jens Titze, Dominik N Müller, Waldemar Kolanus, Joachim L Schultze, Stefan Wagner, Jonathan Jantsch

Source: PLoS Biology, Vol 18, Iss 6, p e3000722 (2020)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/3249cb09b6b04812ba5cea7c7d2e59d9

Prolonged IKKβ Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells

Authors: Christoph Heuser, Janine Gotot, Eveline Christina Piotrowski, Marie-Sophie Philipp, Christina Johanna Felicia Courrèges, Martin Sylvester Otte, Linlin Guo, Jonathan Leo Schmid-Burgk, Veit Hornung, Annkristin Heine, Percy Alexander Knolle, Natalio Garbi, Edgar Serfling, César Evaristo, Friedrich Thaiss, Christian Kurts

Source: Cell Reports, Vol 21, Iss 3, Pp 578-586 (2017)

Subject Terms: regulatory T cells, NF-κB pathway, tumor vaccination, checkpoint inhibition, cytotoxic T cells, cross-priming, apoptosis, tumor immunology, melanoma, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717313876; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/4b8d2a01267d445e902b9141cf3081ba

Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination

Authors: Annkristin Heine, Chrystel Flores, Heidrun Gevensleben, Linda Diehl, Mathias Heikenwalder, Marc Ringelhan, Klaus-Peter Janssen, Ulrich Nitsche, Natalio Garbi, Peter Brossart, Percy A. Knolle, Christian Kurts, Bastian Höchst

Source: OncoImmunology, Vol 6, Iss 8 (2017)

Subject Terms: atra, immunotherapy, mdscs, therapeutical vaccination, tumor immune escape, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/dee0c88e8cc44908a3bacdfa7773b814

IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function

Authors: Jan P. Böttcher, Oliver Schanz, Christoph Garbers, Anne Zaremba, Silke Hegenbarth, Christian Kurts, Marc Beyer, Joachim L. Schultze, Wolfgang Kastenmüller, Stefan Rose-John, Percy A. Knolle

Source: Cell Reports, Vol 8, Iss 5, Pp 1318-1327 (2014)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124714005750; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/1faa4c3286d149e591e9d48f7f359528

Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity

Authors: Jan P. Böttcher, Oliver Schanz, Dirk Wohlleber, Zeinab Abdullah, Svenja Debey-Pascher, Andrea Staratschek-Jox, Bastian Höchst, Silke Hegenbarth, Jessica Grell, Andreas Limmer, Imke Atreya, Markus F. Neurath, Dirk H. Busch, Edgar Schmitt, Peter van Endert, Waldemar Kolanus, Christian Kurts, Joachim L. Schultze, Linda Diehl, Percy A. Knolle

Source: Cell Reports, Vol 3, Iss 3, Pp 779-795 (2013)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124713000673; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/707c86f231ea47f7a294b44c348f41e4

TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation

Authors: Dirk Wohlleber, Hamid Kashkar, Katja Gärtner, Marianne K. Frings, Margarete Odenthal, Silke Hegenbarth, Carolin Börner, Bernd Arnold, Günter Hämmerling, Bernd Nieswandt, Nico van Rooijen, Andreas Limmer, Karin Cederbrant, Mathias Heikenwalder, Manolis Pasparakis, Ulrike Protzer, Hans-Peter Dienes, Christian Kurts, Martin Krönke, Percy A. Knolle

Source: Cell Reports, Vol 2, Iss 3, Pp 478-487 (2012)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124712002264; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/a497e482dddd436a850ec6840fdbdfaf

Recombinant HLA-G as Tolerogenic Immunomodulant in Experimental Small Bowel Transplantation.

Authors: Martin W von Websky, Koji Kitamura, Isis Ludwig-Portugall, Christian Kurts, Maximilian von Laffert, Joel LeMaoult, Edgardo D Carosella, Kareem Abu-Elmagd, Joerg C Kalff, Nico Schäfer

Source: PLoS ONE, Vol 11, Iss 7, p e0158907 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4942037?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/380a11ca542949b9b517a02a1ed3393a