LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype

Authors: Nadia Cobo‐Vuilleumier, Silvia Rodríguez‐Fernandez, Livia López‐Noriega, Petra I. Lorenzo, Jaime M. Franco, Christian C. Lachaud, Eugenia Martin Vazquez, Raquel Araujo Legido, Akaitz Dorronsoro, Raul López‐Férnandez‐Sobrino, Beatriz Fernández‐Santos, Carmen Espejo Serrano, Daniel Salas‐Lloret, Nila vanOverbeek, Mireia Ramos‐Rodriguez, Carmen Mateo‐Rodríguez, Lucia Hidalgo, Sandra Marin‐Canas, Rita Nano, Ana I. Arroba, Antonio Campos Caro, Alfred CO Vertegaal, Alejandro Martín‐Montalvo, Franz Martín, Manuel Aguilar‐Diosdado, Lorenzo Piemonti, Lorenzo Pasquali, Roman González Prieto, Maria Isabel García Sánchez, Decio L. Eizirik, Maria Asuncion Martínez‐Brocca, Marta Vives‐Pi, Benoit R. Gauthier

Source: Clinical and Translational Medicine, Vol 14, Iss 12, Pp n/a-n/a (2024)

Subject Terms: autoimmune diseases, drug development, immune tolerance, pancreatic islets, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/c5769c438c404765859eb6683cbbb639

miR-7 Modulates hESC Differentiation into Insulin-Producing Beta-like Cells and Contributes to Cell Maturation

Authors: Javier López-Beas, Vivian Capilla-González, Yolanda Aguilera, Nuria Mellado, Christian C. Lachaud, Franz Martín, Tarik Smani, Bernat Soria, Abdelkrim Hmadcha

Source: Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 463-477 (2018)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S216225311830129X; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/01e96c41e1e04a21b7c87ff2ad585c40

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Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.

Authors: Daniela Pezzolla, Javier López-Beas, Christian C Lachaud, Alejandro Domínguez-Rodríguez, Tarik Smani, Abdelkrim Hmadcha, Bernat Soria

Source: PLoS ONE, Vol 10, Iss 3, p e0119904 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4361612?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8538e6537e774c25a15708b1e97b07dd

Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.

Authors: Cintia Roodveldt, Adahir Labrador-Garrido, Elena Gonzalez-Rey, Christian C Lachaud, Tim Guilliams, Rafael Fernandez-Montesinos, Alicia Benitez-Rondan, Gema Robledo, Abdelkrim Hmadcha, Mario Delgado, Christopher M Dobson, David Pozo

Source: PLoS ONE, Vol 8, Iss 11, p e79160 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3827304?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c835f4a1e7ca4de79569f7b7d909ccf7

Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.

Authors: Cintia Roodveldt, Adahir Labrador-Garrido, Elena Gonzalez-Rey, Rafael Fernandez-Montesinos, Marta Caro, Christian C Lachaud, Christopher A Waudby, Mario Delgado, Christopher M Dobson, David Pozo

Source: PLoS ONE, Vol 5, Iss 10, p e13481 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2964342?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/626b309d36ba40c8af5fced3b256c966