Mixed methods study of views and experience of non-hospitalised individuals with long COVID of using pacing interventions

Authors: Christel McMullan, Shamil Haroon, Grace Turner, Olalekan Lee Aiyegbusi, Sarah E. Hughes, Sarah Flanagan, Anuradhaa Subramanian, Krish Nirantharakumar, Elin Haf Davies, Chris Frost, Louise Jackson, Naijie Guan, Yvonne Alder, Amy Chong, Lewis Buckland, Felicity Jeyes, David Stanton, Melanie Calvert

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-11 (2025)

Subject Terms: Pacing, Qualitative, Long Covid, Mixed methods, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ef1e9646a6134396b4ff7f44ea69b78a

Key considerations for digital decentralised clinical trials from a feasibility study assessing pacing interventions for long COVID

Authors: Christel McMullan, Shamil Haroon, Grace Turner, Olalekan Lee Aiyegbusi, Anuradhaa Subramanian, Sarah E. Hughes, Sarah Flanagan, Krishnarajah Nirantharakumar, Elin Haf Davies, Chris Frost, Louise Jackson, Naijie Guan, Yvonne Alder, Amy Chong, Lewis Buckland, Felicity Jeyes, David Stanton, Melanie Calvert

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Subject Terms: Decentralised trials, Feasibility study, Pacing intervention, PROMs, Long COVID, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a5cb3cd57e1e4eccbd6fdf3518bec703

Community health promotion and medical provision and impact on neonates (CHAMPION2) and support to rural India’s public education system and impact on numeracy and literacy scores (STRIPES2): an update to the study protocol (v 11) for a cluster randomised trial in Madhya Pradesh, India

Authors: Siddharudha Shivalli, Ila Fazzio, Chris Frost, Diana Elbourne, Nicholas Magill, Dropti Sharma, Sajjan Singh Shekhawat, Rukmini Banerji, Sridevi Karnati, Harshavardhan Reddy, Padmanabh Reddy, Rakhi Nair, Madan Gopal, Peter Boone

Source: Trials, Vol 25, Iss 1, Pp 1-8 (2024)

Subject Terms: Cluster randomised controlled trial, India, Neonatal mortality, Immediate neonatal care, Postnatal care, Maternal mortality, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/e49f9dfdb68f44ca8684a9e776138f58

Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK

Authors: Alan J Thompson, Charles Wade, Nevin John, Jeremy Chataway, Gavin Giovannoni, Rachael Hunter, Sreedharan Harikrishnan, Floriana De Angelis, Olga Ciccarelli, Eli Silber, John Greenwood, Thomas Williams, Martin Duddy, Basil Sharrack, Annie Hawton, Siddharthan Chandran, Sue Pavitt, Paul Gallagher, Ian Galea, Jennifer M Nicholas, Tarunya Arun, Miriam Mattoscio, Richard Nicholas, Neil Robertson, Carolyn Young, Jeremy Hobart, David Rog, Owen Pearson, Anisha Doshi, Timothy Harrower, Leonora Fisniku, Ruth Geraldes, Nikos Evangelou, Judy Beveridge, Matthew Craner, Don Mahad, Stefano Pluchino, Suresh Chhetri, Susan Tebbs, Marie Braisher, Seema Kalra, Charles Hillier, Chris Frost, Gavin McDonnell, Stuart J Nixon, Helen L Ford, Jeban Ganesalingam, Claire Rice, Alberto Calvi, Cord Spilker, Abdullah Shehu, Martin Lee, James Blackstone, Alessia Bianchi, Agne Straukiene, Gil Barton, Fayyaz Ahmed, Dawn Lyle, Ekaterina Bordea, Sean Apap Mangion, Rachel Merry, Elisabeth Jarman

Source: BMJ Open, Vol 14, Iss 9 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/9/e086414.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/69619bde66e34a6986cbeaf0b8bdc802

Investigating the relationship between thalamic iron concentration and disease severity in secondary progressive multiple sclerosis using quantitative susceptibility mapping: Cross-sectional analysis from the MS-STAT2 randomised controlled trial

Authors: Thomas Williams, Nevin John, Alberto Calvi, Alessia Bianchi, Floriana De Angelis, Anisha Doshi, Sarah Wright, Madiha Shatila, Marios C. Yiannakas, Fatima Chowdhury, Jon Stutters, Antonio Ricciardi, Ferran Prados, David MacManus, Francesco Grussu, Anita Karsa, Becky Samson, Marco Battiston, Claudia A.M. Gandini Wheeler-Kingshott, Karin Shmueli, Olga Ciccarelli, Frederik Barkhof, Jeremy Chataway, Wallace Brownlee, Claudia AM. Gandini Wheeler-Kingshott, Jonathan Stutters, Ferran Prados Carrasco, Marios Yiannakas, Megan Wynne, Marie Braisher, James Blackstone, Leanne Hockey, Josephine Parker, Jennifer Flight, Chris Frost, Jennifer Nicholas, Stuart Nixon, Judy Beveridge

Source: Neuroimage: Reports, Vol 4, Iss 3, Pp 100216- (2024)

Subject Terms: Multiple sclerosis, Deep grey matter, Thalamus, Iron, Quantitative susceptibility mapping, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666956024000229; https://doaj.org/toc/2666-9560

Access URL: https://doaj.org/article/a5f0c83cc2dc4adf9dbc117e4d8f1ca0

Statistical analysis plan for a cluster randomised trial in Madhya Pradesh, India: community health promotion and medical provision and impact on neonates (CHAMPION2)

Authors: Nicholas Magill, Siddharudha Shivalli, Ila Fazzio, Diana Elbourne, Suzanne Keddie, Padmanabh Reddy, Rakhi Nair, Madan Gopal, Sridevi Karnati, Harshavardhan Reddy, Peter Boone, Chris Frost

Source: Trials, Vol 25, Iss 1, Pp 1-33 (2024)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/e87308dbbd77443dbcffe72fc4bd5803

How important is the linearity assumption in a sample size calculation for a randomised controlled trial where treatment is anticipated to affect a rate of change?

Authors: Katy E. Morgan, Ian R. White, Chris Frost

Source: BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-19 (2023)

Subject Terms: Random slopes model, Linearity assumption, Sample size calculation, Randomised clinical trial, Model misspecification, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2288

Access URL: https://doaj.org/article/4fe16e135a4b4d24bdb06c7b2cf67e40

Development and usability testing of an electronic patient-reported outcome (ePRO) solution for patients with inflammatory diseases in an Advanced Therapy Medicinal Product (ATMP) basket trial

Authors: Christel McMullan, Ameeta Retzer, Sarah E. Hughes, Olalekan Lee Aiyegbusi, Camilla Bathurst, Alan Boyd, Jamie Coleman, Elin Haf Davies, Alastair K. Denniston, Helen Dunster, Chris Frost, Rosie Harding, Amanda Hunn, Derek Kyte, Rebecca Malpass, Gary McNamara, Sandra Mitchell, Saloni Mittal, Philip N. Newsome, Gary Price, Anna Rowe, Wilma van Reil, Anita Walker, Roger Wilson, Melanie Calvert

Source: Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-13 (2023)

Subject Terms: Electronic patient reported outcomes, Usability testing, Inflammatory conditions, Cognitive interviews, Early phase advanced therapy trial, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/2509-8020

Access URL: https://doaj.org/article/1f4183a1c1e54a1a8341cfe7200a5ed5

Effects of Route Complexity and Lighting on Route Following in Alzheimer’s Disease and Posterior Cortical Atrophy

Authors: Amelia M. Carton, Chris Frost, Teresa Poole, Biao Yang, Ian D. McCarthy, Tatsuto Suzuki, Catherine Holloway, Robin Serougne, Derrick Boampong, Mary Pat Sullivan, Nick Tyler, Sebastian Crutch, Keir X. X. Yong

Source: Brain Sciences, Vol 14, Iss 12, p 1217 (2024)

Subject Terms: Alzheimer’s disease, built environment, dementia, accessibility, inertial measurement units, navigation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/14/12/1217; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/12b19a10f66d432094c3b9352c1803a1

Statistical analysis plan for a cluster randomised trial in Madhya Pradesh, India: support to rural India’s public education system and impact on numeracy and literacy scores (STRIPES2)

Authors: Suzanne Keddie, Ila Fazzio, Siddharudha Shivalli, Nicholas Magill, Diana Elbourne, Dropti Sharma, Sajjan Singh Shekhawat, Rukmini Banerji, Sridevi Karnati, Harshavardhan Reddy, Alex Eble, Peter Boone, Chris Frost

Source: Trials, Vol 24, Iss 1, Pp 1-16 (2023)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/1108cafa62064e6088b72d6711900eec

Effects of the visual environment on object localization in posterior cortical atrophy and typical Alzheimer's disease

Authors: Dilek Ocal, Ian D. McCarthy, Teresa Poole, Silvia Primativo, Tatsuto Suzuki, Nick Tyler, Chris Frost, Sebastian J. Crutch, Keir X. X. Yong

Source: Frontiers in Medicine, Vol 10 (2023)

Subject Terms: posterior cortical atrophy, object localization, dementia, vision, clutter, reaching, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1102510/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/b8dffadddb2249d6a8c7dc13a77b6cc7

Feasibility of a new electronic patient-reported outcome (ePRO) system for an advanced therapy clinical trial in immune-mediated inflammatory disease (PROmics): protocol for a qualitative feasibility study

Authors: Ameeta Retzer, Christel McMullan, Melanie Calvert, Gary Price, Sarah E Hughes, Elin Haf Davies, Anna Rowe, Chris Frost, Roger Wilson, Philip N Newsome, Anita Walker, Gary McNamara, Rebecca Malpass, Camilla Bathurst, Rosie Harding

Source: BMJ Open, Vol 12, Iss 9 (2022)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/12/9/e063199.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/7fd415117cb1499ca1fce27038899080

Protocol for a cluster randomised trial in Madhya Pradesh, India: community health promotion and medical provision and impact on neonates (CHAMPION2); and support to rural India’s public education system and impact on numeracy and literacy scores (STRIPES2)

Authors: Arjun Agarwal, Rukmini Banerji, Peter Boone, Diana Elbourne, Ila Fazzio, Chris Frost, Madan Gopal, Sridevi Karnati, Rakhi Nair, Harshavardhan Reddy, Padmanabh Reddy, Dropti Sharma, Sajjan Singh Shekhawat, Siddharudha Shivalli

Source: Trials, Vol 21, Iss 1, Pp 1-18 (2020)

Subject Terms: Cluster randomised controlled trial, India, Neonatal mortality, Immediate neonatal care, Postnatal care, Maternal mortality, Medicine (General), R5-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13063-020-04339-6; https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/308a4a251be24ef198bb3b75806ec952

The effects of sleep on firefighter occupational performance and health: A systematic review and call for action

Authors: Chris Frost, Mike Toczko, Justin J. Merrigan, Joel R. Martin

Source: Sleep Epidemiology, Vol 1, Iss , Pp 100014- (2021)

Subject Terms: Fatigue, Alertness, Occupational readiness, Emergency responders, Tactical, Occupational Preparedness, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667343621000147; https://doaj.org/toc/2667-3436

Access URL: https://doaj.org/article/a0f5cb08d7bb4f9bacf08c5a52d41b70

The HOME Study: Statistical and economic analysis plan for a randomised controlled trial comparing the addition of Proactive Psychological Medicine to usual care, with usual care alone, on the time spent in hospital by older acute hospital inpatients

Authors: Nicholas Magill, Ian R. White, Jane Walker, Katy Burke, Mark Toynbee, Maike van Niekerk, Fan Yang, Simon Walker, Mark Sculpher, Michael Sharpe, Chris Frost

Source: Trials, Vol 21, Iss 1, Pp 1-14 (2020)

Subject Terms: Randomised controlled trial, Statistical analysis plan, Psychological medicine, Liaison psychiatry, Multi-morbidity, Medicine (General), R5-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13063-020-04256-8; https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/213c9e34ad7b422d8fc83a40c79f7783

The association between anthropometric measures of adiposity and the progression of carotid atherosclerosis

Authors: Yume Imahori, Ellisiv B. Mathiesen, Katy E. Morgan, Chris Frost, Alun D. Hughes, Laila A. Hopstock, Stein Harald Johnsen, Nina Emaus, David A. Leon

Source: BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-10 (2020)

Subject Terms: Obesity, Abdominal obesity, Atherosclerosis, Carotid plaque, Epidemiology, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12872-020-01417-0; https://doaj.org/toc/1471-2261

Access URL: https://doaj.org/article/0b381780bf9c49f8b4c793910916c3d2

The HOME Study: study protocol for a randomised controlled trial comparing the addition of Proactive Psychological Medicine to usual care, with usual care alone, on the time spent in hospital by older acute hospital inpatients

Authors: Jane Walker, Katy Burke, Mark Toynbee, Maike van Niekerk, Chris Frost, Nicholas Magill, Simon Walker, Mark Sculpher, Ian R. White, Michael Sharpe

Source: Trials, Vol 20, Iss 1, Pp 1-9 (2019)

Subject Terms: Randomised controlled trial, protocol, psychological medicine, liaison psychiatry, multi-morbidity, Medicine (General), R5-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13063-019-3502-5; https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/fbfcbb6a957f46ab8493fcb29dd9105f

Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease

Authors: Philip S. J. Weston, Teresa Poole, Antoinette O’Connor, Amanda Heslegrave, Natalie S. Ryan, Yuying Liang, Ronald Druyeh, Simon Mead, Kaj Blennow, Jonathan M. Schott, Chris Frost, Henrik Zetterberg, Nick C. Fox

Source: Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-7 (2019)

Subject Terms: Search terms, [26] Alzheimer’s disease, [91] autosomal dominant, [111] neurofilament light, [111] blood, [111] longitudinal, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13195-019-0472-5; https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/e03e6ca436714f19ae34bfbeb8723d84

Effects of lighting variability on locomotion in posterior cortical atrophy

Authors: Keir X. X. Yong, Ian D. McCarthy, Teresa Poole, Dilek Ocal, Ayako Suzuki, Tatsuto Suzuki, Kyriaki Mengoudi, Nikolaos Papadosifos, Derrick Boampong, Nick Tyler, Chris Frost, Sebastian J. Crutch

Source: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)

Subject Terms: Alzheimer's disease, dementia, locomotion, posterior cortical atrophy, visual perception, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8737

Access URL: https://doaj.org/article/f2c265483c3d4ac5b6e827468f5cbfc1

Detection and localisation of hesitant steps in people with Alzheimer's disease navigating routes of varying complexity

Authors: Ian McCarthy, Tatsuto Suzuki, Catherine Holloway, Teresa Poole, Chris Frost, Amelia Carton, Nick Tyler, Sebastian Crutch, Keir Yong

Source: Healthcare Technology Letters (2019)

Subject Terms: statistical analysis, diseases, gait analysis, biomedical measurement, patient monitoring, walking paths, step hesitancy, route complexity, Alzheimer's disease navigating routes, abnormal gait parameters, gait irregularities, adaptive locomotor responses, spatial navigation, corridors, dog-leg, counterbalanced repeated-measures design, posterior cortical atrophy, shoe-mounted inertial measurement units, step time data, position data, Alzheimer's disease, gait characteristics, IMU acceleration, statistical analysi, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://digital-library.theiet.org/content/journals/10.1049/htl.2018.5034; https://doaj.org/toc/2053-3713

Access URL: https://doaj.org/article/a74701ba0a864f6a86337e1a2d1a1694