Choosing the right mouse model: comparison of humanized NSG and NBSGW mice for in vivo HSC gene therapy

Authors: Choo, Seunga, Wolf, Carl B., Mack, Heather M., Egan, Mitchell J., Kiem, Hans-Peter, Radtke, Stefan

Source: In Blood Advances 27 February 2024 8(4):916-926

CD90-targeted lentiviral vectors for HSC gene therapy

Authors: Berckmueller, Kurt, Thomas, Justin, Taha, Eman A., Choo, Seunga, Madhu, Ravishankar, Kanestrom, Greta, Rupert, Peter B., Strong, Roland, Kiem, Hans-Peter, Radtke, Stefan

Source: In Molecular Therapy 4 October 2023 31(10):2901-2913

Editing TINF2 as a potential therapeutic approach to restore telomere length in dyskeratosis congenita

Authors: Choo, Seunga ^*, Lorbeer, Franziska K. ^*, Regalado, Samuel G., Short, Sarah B., Wu, Shannon, Rieser, Gabrielle, Bertuch, Alison A., Hockemeyer, Dirk ^*

Source: In Blood 11 August 2022 140(6):608-618

Cancer‐associated POT1 mutations lead to telomere elongation without induction of a DNA damage response

Authors: Kim, Won‐Tae, Hennick, Kelsey, Johnson, Joshua, Finnerty, Brendan, Choo, Seunga, Short, Sarah B, Drubin, Casey, Forster, Ryan, McMaster, Mary L, Hockemeyer, Dirk

Source: EMBO journal. 40(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122629415.0x000001&indx=1&recIds=ETOCvdc_100122629415.0x000001

Genetic Dissection of Dyskeratosis Congenita-Causing Mutations in TINF2 Using Human Pluripotent and Hematopoietic Stem Cell Models

Authors: Choo, Seunga, Lorbeer, Franziska K., Regalado, Samuel G., Short, Sarah B., Wu, Shannon, Rieser, Gabrielle, Bertuch, Alison A., Hockemeyer, Dirk

Source: In Blood 23 November 2021 138 Supplement 1:2178-2178

TINF2 is a haploinsufficient tumor suppressor that limits telomere length.

Authors: Schmutz, Isabelle, Mensenkamp, Arjen R., Takai, Kaori K., Haadsma, Maaike, Spruijt, Liesbeth, de Voer, Richarda M., Choo, Seunga Sara, Lorbeer, Franziska K., van Grinsven, Emma J., Hockemeyer, Dirk, Jongmans, Marjolijn C. J., de Lange, Titia

Source: eLife; 12/1/2020, p1-20, 20p

Blueprint for a pop-up SARS-CoV-2 testing lab.

Authors: IGI Testing Consortium, Amen, Alexandra M., Barry, Kerrie W., Boyle, John M., Brook, Cara E., Choo, Seunga, Cornmesser, L. T., Dilworth, David J., Doudna, Jennifer A., Ehrenberg, Alexander J., Fedrigo, Indro, Friedline, Skyler E., Graham, Thomas G. W., Green, Ralph, Hamilton, Jennifer R., Hirsh, Ariana, Hochstrasser, Megan L., Hockemeyer, Dirk, Krishnappa, Netravathi, Lari, Azra

Source: Nature Biotechnology; Jul2020, Vol. 38 Issue 7, p791-797, 7p, 1 Color Photograph, 1 Diagram, 1 Chart

Editing TINF2as a therapeutic approach to restore telomere length in dyskeratosis congenita

Authors: Choo, Seunga, Lorbeer, Franziska K., Regalado, Samuel G., Short, Sarah B., Wu, Shannon, Rieser, Gabrielle, Bertuch, Alison A., Hockemeyer, Dirk

Source: Blood; 20240101, Issue: Preprints

Genetic Dissection of Dyskeratosis Congenita-Causing Mutations in TINF2Using Human Pluripotent and Hematopoietic Stem Cell Models

Authors: Choo, Seunga, Lorbeer, Franziska K., Regalado, Samuel G., Short, Sarah B., Wu, Shannon, Rieser, Gabrielle, Bertuch, Alison A., Hockemeyer, Dirk

Source: Blood; November 2021, Vol. 138 Issue: 1, Number 1 Supplement 1 p2178-2178, 1p