RXR agonist, 9-cis-13,14-dihydroretinoic acid (9CDHRA), reduces damage and protects from demyelination in transsynaptic degeneration model

Authors: Parrilla, Gabriella E., Vander Wall, Roshana, Chitranshi, Nitin, Basavarajappa, Devaraj, Gupta, Vivek, Graham, Stuart L., You, Yuyi

Source: In Neuroscience 1 November 2024 559:91-104

Mitochondrial signaling pathways and their role in cancer drug resistance

Authors: Sharma, Ashwani, Virmani, Tarun, Kumar, Girish, Sharma, Anjali, Virmani, Reshu, Gugulothu, Dalapathi, Singh, Kuldeep, Misra, Shashi Kiran, Pathak, Kamla, Chitranshi, Nitin, Coutinho, Henrique Douglas Melo, Jain, Divya

Source: In Cellular Signalling October 2024 122

Genetic Risk, Inflammation, and Therapeutics: An Editorial Overview of Recent Advances in Aging Brains and Neurodegeneration.

Authors: Gupta, Vivek¹ vivek.gupta@mq.edu.au, Chitranshi, Nitin¹, Gupta, Veer Bala²

Source: Aging & Disease. Oct2024, Vol. 15 Issue 5, p1989-1993. 5p.

Subject Terms: *GENETIC algorithms, *INFLAMMATION, *NEURODEGENERATION

Signalling pathways and cell death mechanisms in glaucoma: Insights into the molecular pathophysiology

Authors: Basavarajappa, Devaraj, Galindo-Romero, Caridad, Gupta, Vivek, Agudo-Barriuso, Marta, Gupta, Veer B., Graham, Stuart L., Chitranshi, Nitin

Source: In Molecular Aspects of Medicine December 2023 94

Neuroserpin gene therapy inhibits retinal ganglion cell apoptosis and promotes functional preservation in glaucoma

Authors: Chitranshi, Nitin, Rajput, Rashi, Godinez, Angela, Pushpitha, Kanishka, Mirzaei, Mehdi, Basavarajappa, Devaraj, Gupta, Veer, Sharma, Samridhi, You, Yuyi, Galliciotti, Giovanna, Salekdeh, Ghasem H., Baker, Mark S., Graham, Stuart L., Gupta, Vivek K.

Source: In Molecular Therapy 5 July 2023 31(7):2056-2076

Extracellular vesicles as reconfigurable therapeutics for eye diseases: Promises and hurdles

Authors: Shekari, Faezeh, Abyadeh, Morteza, Meyfour, Anna, Mirzaei, Mehdi, Chitranshi, Nitin, Gupta, Vivek, Graham, Stuart L., Salekdeh, Ghasem Hosseini

Source: In Progress in Neurobiology June 2023 225

Chitosan modified 5-fluorouracil nanostructured lipid carriers for treatment of diabetic retinopathy in rats: A new dimension to an anticancer drug

Authors: Sharma, Deep Shikha, Wadhwa, Sheetu, Gulati, Monica, Kumar, Bimlesh, Chitranshi, Nitin, Gupta, Vivek Kumar, Alrouji, Mohammed, Alhajlah, Sharif, AlOmeir, Othman, Vishwas, Sukriti, Khursheed, Rubiya, Saini, Sumant, Kumar, Ankit, Parveen, Shaik Rahana, Gupta, Gaurav, Zacconi, Flavia, Chellappan, Dinesh Kumar, Morris, Andrew, Loebenberg, Raimar, Dua, Kamal, Singh, Sachin Kumar

Source: In International Journal of Biological Macromolecules 1 January 2023 224:810-830

Retinoid X receptor agonist 9CDHRA mitigates retinal ganglion cell apoptosis and neuroinflammation in a mouse model of glaucoma.

Authors: Basavarajappa, Devaraj¹ (AUTHOR) devaraj.basavarajappa@mq.edu.au, Chitranshi, Nitin¹ (AUTHOR), Oddin Mirshahvaladi, Seyed Shahab¹ (AUTHOR), Gupta, Veer B.² (AUTHOR), Palanivel, Viswanthram¹ (AUTHOR), Parrilla, Gabriella E.¹ (AUTHOR), Salkar, Akanksha¹ (AUTHOR), Mirzaei, Mehdi¹ (AUTHOR), Komáromy, András M.³ (AUTHOR), Krezel, Wojciech⁴ (AUTHOR), Graham, Stuart L.¹ (AUTHOR), Gupta, Vivek¹ (AUTHOR)

Source: FASEB Journal. 3/31/2025, Vol. 39 Issue 6, p1-18. 18p.

TrkB Receptor Agonist 7,8 Dihydroxyflavone is Protective Against the Inner Retinal Deficits Induced by Experimental Glaucoma

Authors: Gupta, Vivek, Chitranshi, Nitin, Gupta, Veer, You, Yuyi, Rajput, Rashi, Paulo, Joao A., Mirzaei, Mehdi, van den Buuse, Maarten, Graham, Stuart L.

Source: In Neuroscience 10 May 2022 490:36-48

Trans-synaptic degeneration in the visual pathway: Neural connectivity, pathophysiology, and clinical implications in neurodegenerative disorders

Authors: Sharma, Samridhi, Chitranshi, Nitin, Wall, Roshana Vander, Basavarajappa, Devaraj, Gupta, Vivek, Mirzaei, Mehdi, Graham, Stuart L, Klistorner, Alexander, You, Yuyi

Source: In Survey of Ophthalmology March-April 2022 67(2):411-426

Evaluating associations of RNFL thickness and multifocal VEP with cognitive assessment and brain MRI volumes in older adults: Optic nerve decline and cognitive change (ONDCC) initiative

Authors: Shen, Ting, Sheriff, Samran, You, Yuyi, Jiang, Jiyang, Schulz, Angela, Francis, Heather, Mirzaei, Mehdi, Saks, Danit, Chitranshi, Nitin, Gupta, Veer, Singh, Maria Fiatarone, Klistorner, Alexander, Wen, Wei, Sachdev, Perminder, Gupta, Vivek K., Graham, Stuart L.

Source: In Neurobiology of Aging Science 2022 2

Retinal changes in Alzheimer's disease— integrated prospects of imaging, functional and molecular advances

Authors: Gupta, Veer B., Chitranshi, Nitin, den Haan, Jurre, Mirzaei, Mehdi, You, Yuyi, Lim, Jeremiah KH., Basavarajappa, Devaraj, Godinez, Angela, Di Angelantonio, Silvia, Sachdev, Perminder, Salekdeh, Ghasem H., Bouwman, Femke, Graham, Stuart, Gupta, Vivek

Source: In Progress in Retinal and Eye Research May 2021 82

Development of modified apple polysaccharide capped silver nanoparticles loaded with mesalamine for effective treatment of ulcerative colitis

Authors: Kaur, Gurmandeep, Singh, Sachin Kumar, Kumar, Rajesh, Kumar, Bimlesh, Kumari, Yogita, Gulati, Monica, Pandey, Narendra Kumar, Gowthamarajan, K., Ghosh, Dipanjoy, Clarisse, A., Wadhwa, Sheetu, Mehta, Meenu, Satija, Saurabh, Dua, Kamal, Dureja, Harish, Gupta, Saurabh, Singh, Pankaj Kumar, Kapoor, Bhupinder, Chitranshi, Nitin, Kumar, Ankit, Porwal, Omji

Source: In Journal of Drug Delivery Science and Technology December 2020 60

Retinoid x receptor modulation protects against ER stress response and rescues glaucoma phenotypes in adult mice

Authors: Dheer, Yogita, Chitranshi, Nitin, Gupta, Veer, Sharma, Samridhi, Pushpitha, Kanishka, Abbasi, Mojdeh, Mirzaei, Mehdi, You, Yuyi, Graham, Stuart L., Gupta, Vivek

Source: In Experimental Neurology April 2019 314:111-125

Differing Structural and Functional Patterns of Optic Nerve Damage in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

Authors: Shen, Ting, You, Yuyi, Arunachalam, Sukanya, Fontes, Ariadna, Liu, Sidong, Gupta, Vivek, Parratt, John, Wang, Chenyu, Barnett, Michael, Barton, Joshua, Chitranshi, Nitin, Zhu, Ling, Fraser, Clare L., Graham, Stuart L., Klistorner, Alexander, Yiannikas, Con

Source: In Ophthalmology March 2019 126(3):445-453

Glial Cell Activation and Immune Responses in Glaucoma: A Systematic Review of Human Postmortem Studies of the Retina and Optic Nerve.

Authors: Salkar, Akanksha, Wall, Roshana Vander, Basavarajappa, Devaraj, Chitranshi, Nitin, Parilla, Gabriella E., Mirzaei, Mehdi, Peng Yan, Graham, Stuart, Yuyi You

Source: Aging & Disease; Oct2024, Vol. 15 Issue 5, p2069-2083, 15p

Subject Terms: NEUROGLIA, GLAUCOMA, PATHOGENESIS

Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects.

Authors: Ting Shen, Sheriff, Samran, Yuyi You, Jiyang Jiang, Schulz, Angela, Francis, Heather, Mirzaei, Mehdi, Saks, Danit, Palanivel, Viswanthram, Basavarajappa, Devaraj, Chitranshi, Nitin, Gupta, Veer, Wen, Wei, Sachdev, Perminder S., Huixun Jia, Xiaodong Sun, Graham, Stuart L., Gupta, Vivek K.

Source: Aging & Disease; Oct2024, Vol. 15 Issue 5, p2315-2327, 13p

Subject Terms: BRAIN-derived neurotrophic factor, OPTIC nerve, GENETIC polymorphisms

Molecular Mechanisms of Glaucoma Pathogenesis with Implications to Caveolin Adaptor Protein and Caveolin- Shp2 Axis.

Authors: Abbasi, Mojdeh, Gupta, Vivek, Chitranshi, Nitin, Moustardas, Petros, Ranjbaran, Reza, Graham, Stuart L.

Source: Aging & Disease; Oct2024, Vol. 15 Issue 5, p2051-2068, 18p

Subject Terms: GLAUCOMA, CAVEOLINS

Loss of Shp2 Rescues BDNF/TrkB Signaling and Contributes to Improved Retinal Ganglion Cell Neuroprotection

Authors: Chitranshi, Nitin, Dheer, Yogita, Mirzaei, Mehdi, Wu, Yunqi, Salekdeh, Ghasem H., Abbasi, Mojdeh, Gupta, Veer, Vander Wall, Roshana, You, Yuyi, Graham, Stuart L., Gupta, Vivek

Source: In Molecular Therapy 6 February 2019 27(2):424-441

PTPN11 induces endoplasmic stress and apoptosis in SH-SY5Y cells

Authors: Chitranshi, Nitin, Dheer, Yogita, Gupta, Veer, Abbasi, Mojdeh, Mirzaei, Mehdi, You, Yuyi, Chung, Roger, Graham, Stuart L., Gupta, Vivek

Source: In Neuroscience 19 November 2017 364:175-189