LLMs are Biased Evaluators But Not Biased for Retrieval Augmented Generation

Authors: Chen, Yen-Shan, Jin, Jing, Kuo, Peng-Ting, Huang, Chao-Wei, Chen, Yun-Nung

Subject Terms: Computer Science - Computation and Language

Access URL: http://arxiv.org/abs/2410.20833

Role of nucleobase-specific interactions in the binding and bending of DNA by human male sex determination factor SRY

Authors: Racca, Joseph D., Chen, Yen-Shan, Brabender, Adam R., Battistin, Umberto, Weiss, Michael A., Georgiadis, Millie M.

Source: In Journal of Biological Chemistry September 2024 300(9)

Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone–receptor activation

Authors: Chen, Yen-Shan, Gleaton, Jeremy, Yang, Yanwu, Dhayalan, Balamurugan, Phillips, Nelson B., Liu, Yule, Broadwater, Laurie, Jarosinski, Mark A., Chatterjee, Deepak, Lawrence, Michael C., Hattier, Thomas, Michael, M. Dodson, Weiss, Michael A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Jul . 118(30), 1-12.

Access URL: https://www.jstor.org/stable/27052610

Generation and mutational analysis of a transgenic mouse model of human SRY

Authors: Thomson, Ella, Zhao, Liang, Chen, Yen‐Shan, Longmuss, Enya, Ng, Ee Ting, Sreenivasan, Rajini, Croft, Brittany, Song, Xin, Sinclair, Andrew, Weiss, Michael, Koopman, Peter, Pelosi, Emanuele

Source: Human mutation. 43(3):362-379

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142232453.0x000001&indx=1&recIds=ETOCvdc_100142232453.0x000001

Stabilization of a protein by a single halogen‐based aromatic amplifier.

Authors: El Hage, Krystel, Dhayalan, Balamurugan, Chen, Yen‐Shan, Phillips, Nelson B., Whittaker, Jonathan, Carr, Kelley, Whittaker, Linda, Phillips, Manijeh H., Ismail‐Beigi, Faramarz, Meuwly, Markus, Weiss, Michael A.

Source: Protein Science: A Publication of the Protein Society; Mar2025, Vol. 34 Issue 3, p1-22, 22p

Synthetic Studies of the Mutant Proinsulin Syndrome Demonstrate Correlation Between Folding Efficiency and Age of Diabetes Onset.

Authors: Dhayalan, Balamurugan¹ (AUTHOR), Chen, Yen-Shan¹ (AUTHOR), Ni, Chun-Lun¹ (AUTHOR), Weiss, Michael A.¹ (AUTHOR) weissma@iu.edu

Source: International Journal of Peptide Research & Therapeutics. Feb2025, Vol. 31 Issue 1, p1-20. 20p.

Evolution of insulin at the edge of foldability and its medical implications

Authors: Rege, Nischay K., Liu, Ming, Yang, Yanwu, Dhayalan, Balamurugan, Wickramasinghe, Nalinda P., Chen, Yen-Shan, Rahimi, Leili, Guo, Huan, Haataja, Leena, Sun, Jinhong, Ismail-Beigi, Faramarz, Phillips, Nelson B., Arvan, Peter, Weiss, Michael A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Nov . 117(47), 29618-29628.

Access URL: https://www.jstor.org/stable/26970814

Structural principles of insulin formulation and analog design: A century of innovation

Authors: Jarosinski, Mark A., Dhayalan, Balamurugan, Chen, Yen-Shan, Chatterjee, Deepak, Varas, Nicolás, Weiss, Michael A.

Source: In Molecular Metabolism October 2021 52

New Horizons: Next-Generation Insulin Analogues: Structural Principles and Clinical Goals

Authors: Jarosinski, Mark A, Chen, Yen-Shan, Varas, Nicolás, Dhayalan, Balamurugan, Chatterjee, Deepak, Weiss, Michael A

Source: Journal of clinical endocrinology & metabolism. 107(4):909-928

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152520271.0x000001&indx=1&recIds=ETOCvdc_100152520271.0x000001

“Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution

Authors: Rege, Nischay K., Liu, Ming, Dhayalan, Balamurugan, Chen, Yen-Shan, Smith, Nicholas A. ^**, Rahimi, Leili, Sun, Jinhong, Guo, Huan, Yang, Yanwu, Haataja, Leena, Phillips, Nelson F.B., Whittaker, Jonathan, Smith, Brian J. ^**, Arvan, Peter, Ismail-Beigi, Faramarz, Weiss, Michael A.

Source: In Journal of Biological Chemistry 6 March 2020 295(10):3080-3098

Reassessment of an Innovative Insulin Analogue Excludes Protracted Action yet Highlights the Distinction between External and Internal Diselenide Bridges

Authors: Dhayalan, Balamurugan, Chen, Yen‐Shan, Phillips, Nelson B., Swain, Mamuni, Rege, Nischay K., Mirsalehi, Ali, Jarosinski, Mark, Ismail‐Beigi, Faramarz, Metanis, Norman, Weiss, Michael A.

Source: Chemistry. 26(21):4695-4700

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106681950.0x000001&indx=1&recIds=ETOCvdc_100106681950.0x000001

An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein

Alternate Title: Heat-stable insulin engineering (English)

Authors: Glidden, Michael D., Aldabbagh, Khadijah, Phillips, Nelson B., Carr, Kelley, Chen, Yen-Shan, Whittaker, Jonathan, Phillips, Manijeh, Wickramasinghe, Nalinda P., Rege, Nischay, Swain, Mamuni, Peng, Yi, Yang, Yanwu, Lawrence, Michael C. ^**, Yee, Vivien C., Ismail-Beigi, Faramarz, Weiss, Michael A.

Source: In Journal of Biological Chemistry 5 January 2018 293(1):47-68

Human Sex Determination at the Edge of Ambiguity: INHERITED XY SEX REVERSAL DUE TO ENHANCED UBIQUITINATION AND PROTEASOMAL DEGRADATION OF A MASTER TRANSCRIPTION FACTOR

Authors: Racca, Joseph D., Chen, Yen-Shan, Yang, Yanwu, Phillips, Nelson B., Weiss, Michael A.

Source: In Journal of Biological Chemistry October 2016 291(42):22173-22195

Se‐Glargine: Chemical Synthesis of a Basal Insulin Analogue Stabilized by an Internal Diselenide Bridge.

Authors: Weil‐Ktorza, Orit, Dhayalan, Balamurugan, Chen, Yen‐Shan, Weiss, Michael A., Metanis, Norman

Source: ChemBioChem; Mar2024, Vol. 25 Issue 5, p1-6, 6p

Structure-Function Relationships in Human Testis-determining Factor SRY: AN AROMATIC BUTTRESS UNDERLIES THE SPECIFIC DNA-BENDING SURFACE OF A HIGH MOBILITY GROUP (HMG) BOX*♦

Authors: Racca, Joseph D., Chen, Yen-Shan, Maloy, James D., Wickramasinghe, Nalinda, Phillips, Nelson B., Weiss, Michael A.

Source: In Journal of Biological Chemistry 21 November 2014 289(47):32410-32429

Inherited human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold

Authors: Chen, Yen-Shan, Racca, Joseph D., Phillips, Nelson B., Weiss, Michael A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Sep . 110(38), 15177-15177.

Access URL: https://www.jstor.org/stable/42713284

Microsatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological novelty

Authors: Chen, Yen-Shan, Racca, Joseph D., Sequeira, Paul W., Phillips, Nelson B., Weiss, Michael A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Aug . 110(33), 13242-13242.

Access URL: https://www.jstor.org/stable/42712883

Nanoporous platinum counter electrodes by glancing angle deposition for dye-sensitized solar cells

Authors: Hsu, Sui-Ying, Tsai, Chih-Hung, Lu, Chun-Yang, Tsai, Yu-Tang, Huang, Tsung-Wei, Jhang, Yuan-Hsuan, Chen, Yan-Fang, Wu, Chung-Chih, Chen, Yen-Shan

Source: In Organic Electronics May 2012 13(5):856-863

Prevalence and Risk Factors for Feeding and Swallowing Difficulties in Spinal Muscular Atrophy Types II and III

Authors: Chen, Yen-Shan, Shih, Hsiang-Hung, Chen, Tai-Heng, Kuo, Chang-Hung, Jong, Yuh-Jyh

Source: In The Journal of Pediatrics March 2012 160(3):447-451

Mammalian Testis-determining Factor SRY and the Enigma of Inherited Human Sex Reversal: FRUSTRATED INDUCED FIT IN A BENT PROTEIN-DNA COMPLEX

Authors: Phillips, Nelson B., Racca, Joseph, Chen, Yen-Shan, Singh, Rupinder, Jancso-Radek, Agnes, Radek, James T., Wickramasinghe, Nalinda P., Haas, Elisha, Weiss, Michael A.

Source: In Journal of Biological Chemistry 21 October 2011 286(42):36787-36807