Desmodium caudatum (Thunb.) DC. extract attenuates hyperuricemia-induced renal fibrosis via modulating TGF-β1 pathway and uric acid transporters: Evidence from in vitro and in vivo studies

Authors: Lin, Hui-Hsuan ^{a, 1}, Liang, Yu-Hsuan ^{b, 1}, Chyau, Charng-Cherng ^c, Tseng, Chiao-Yun ^b, Zhang, Jun-Quan ^b, Chen, Jing-Hsien ^{b, d, ⁎}

Source: In Journal of Ethnopharmacology 9 April 2025 345

The Nephroprotective Effects of Hibiscus sabdariffa Leaf and Ellagic Acid in Vitro and in Vivo Models of Hyperuricemic Nephropathy

Authors: Chen, Jing-Hsien, Wu, Pei-Tzu, Chyau, Charng-Cherng, Wu, Pei-Hsuan, Lin, Hui-Hsuan

Source: Journal of agricultural and food chemistry. 71(1):382-397

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631604997&indx=1&recIds=ETOCRN631604997

The effect of isovitexin on lipopolysaccharide-induced renal injury and inflammation by induction of protective autophagy

Authors: Tseng, Chiao-Yun, Yu, Pei-Rong, Hsu, Cheng-Chin, Lin, Hui-Hsuan, Chen, Jing-Hsien

Source: In Food and Chemical Toxicology February 2023 172

In Vitro and In Vivo Protective Effects of Flavonoid-Enriched Lotus Seedpod Extract on Lipopolysaccharide-Induced Hepatic Inflammation

Authors: Tseng, Hsien-Chun, Tsai, Pei-Min, Chou, Ying-Hsiang, Lee, Yueh-Chun, Lin, Hui-Hsuan, Chen, Jing-Hsien

Source: American journal of Chinese medicine. 47(1):153-176

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619256321&indx=1&recIds=ETOCRN619256321

Taiwanese and Japanese yam (Dioscorea spp.) extracts attenuate doxorubicin-induced cardiotoxicity in mice

Authors: Chen, Chih-Tai, Wang, Zhi-Hong, Hsu, Cheng-Chin, Lin, Hui-Hsuan, Chen, Jing-Hsien

Source: In Journal of Food and Drug Analysis October 2017 25(4):872-880

Inhibition of JNK by pi class of glutathione S-transferase through PKA/CREB pathway is associated with carnosic acid protection against 6-hydroxydopamine-induced apoptosis

Authors: Lin, Chia-Yuan, Fu, Ru-Huei, Chou, Ruey-Hwang, Chen, Jing-Hsien, Wu, Chi-Rei, Chang, Shu-Wei, Tsai, Chia-Wen

Source: In Food and Chemical Toxicology May 2017 103:194-202

Therapeutic Effect of Desmodium caudatum Extracts on Alleviating Diabetic Nephropathy Mice.

Authors: Lin, Hui-Hsuan, Tseng, Chiao-Yun, Yu, Pei-Rong, Ho, Hsiang-Yu, Hsu, Cheng-Chin, Chen, Jing-Hsien

Source: Plant Foods for Human Nutrition; Jun2024, Vol. 79 Issue 2, p374-380, 7p

Subject Terms: STEROL regulatory element-binding proteins, FATTY acid synthases, TREATMENT effectiveness, DIABETIC nephropathies, STAINS & staining (Microscopy), DESMODIUM

In vitro and in vivo protective potential of quercetin-3-glucuronide against lipopolysaccharide-induced pulmonary injury through dual activation of nuclear factor-erythroid 2 related factor 2 and autophagy.

Authors: Yu, Pei-Rong, Tseng, Chiao-Yun, Hsu, Cheng-Chin, Chen, Jing-Hsien, Lin, Hui-Hsuan

Source: Archives of Toxicology; May2024, Vol. 98 Issue 5, p1415-1436, 22p

Subject Terms: LIPOPOLYSACCHARIDES, AUTOPHAGY, PROTHROMBIN, REACTIVE oxygen species, CELL survival, WOUNDS & injuries

Anti-Hypertensive Effect of Solanum muricatum Aiton Leaf Extract In Vivo and In Vitro.

Authors: Lin, Hui-Hsuan, Tsai, Chia-Lin, Tseng, Chiao-Yun, Yu, Pei-Rong, Chiu, Pei-Yu, Hsu, Cheng-Chin, Chen, Jing-Hsien

Source: Plant Foods for Human Nutrition; Mar2024, Vol. 79 Issue 1, p182-188, 7p

Subject Terms: SODIUM channels, ANGIOTENSIN I, NF-kappa B, SOLANUM, NITRIC-oxide synthases, ANTIHYPERTENSIVE agents, ANGIOTENSIN converting enzyme

Anti-cancerous effects of Wasabia japonica extract in Hep3B liver cancer cells via ROS accumulation, DNA damage and p73-mediated apoptosis

Authors: Wu, Shu-Huan, Chyau, Charng-Cherng, Chen, Jing-Hsien, Tu, Shu-Fen, Lin, Hui-Hsuan ^*, Chou, Fen-Pi ^**

Source: In Journal of Functional Foods April 2015 14:445-455

Anti-tumor Effect and Mechanism of Andrographolide

Authors: Lin, Hui-Hsuan, Chen, Jing-Hsien

Source: Taiwan ying yang xue hui za zhi. 41(1):14-24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN606789500&indx=1&recIds=ETOCRN606789500

Anti-atherosclerotic potential of gossypetin via inhibiting LDL oxidation and foam cell formation

Authors: Chen, Jing-Hsien, Tsai, Chia-Wen, Wang, Chi-Ping, Lin, Hui-Hsuan

Source: In Toxicology and Applied Pharmacology 15 October 2013 272(2):313-324

Aqueous extract from Pepino (Solanum muricatum Ait.) leaves ameliorated insulin resistance, hyperlipidemia, and hyperglycemia in mice with metabolic syndrome

Authors: Hsu, Jen‐Ying, Lin, Hui‐Hsuan, Wang, Zhi‐Hong, Chen, Jing‐Hsien

Source: Journal of food biochemistry. 44(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111873198.0x000001&indx=1&recIds=ETOCvdc_100111873198.0x000001

Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells

Authors: Lin, Hui-Hsuan, Tsai, Chia-Wen, Chou, Fen-Pi, Wang, Chau-Jong, Hsuan, Shu-Wen, Wang, Cheng-Kun, Chen, Jing-Hsien

Source: In Toxicology and Applied Pharmacology 1 February 2011 250(3):336-345

Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway

Authors: Lee, Yi-Chieh, Lin, Hui-Hsuan, Hsu, Chin-Hsun, Wang, Chau-Jong, Chiang, Tai-An, Chen, Jing-Hsien

Source: In European Journal of Pharmacology 2010 632(1):23-32

Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down-regulation of MMP-7 expression

Authors: Shi, Ming-Der, Lin, Hui-Hsuan, Chiang, Tai-An, Tsai, Li-Yu, Tsai, Shu-Mei, Lee, Yi-Chieh, Chen, Jing-Hsien

Source: In Chemico-Biological Interactions 2009 180(3):344-352

Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide

Authors: Shi, Ming-Der, Lin, Hui-Hsuan, Lee, Yi-Che, Chao, Jian-Kang, Lin, Rong-An, Chen, Jing-Hsien

Source: In Chemico-Biological Interactions 2008 174(3):201-210

In Vitro and In Vivo Nephroprotective Effects of Nelumbo nucifera Seedpod Extract against Cisplatin-Induced Renal Injury.

Authors: Chen, Jui-Yi, Tsai, Chia-Lin, Tseng, Chiao-Yun, Yu, Pei-Rong, Chang, Yu-Hsuan, Wong, Yue-Ching, Lin, Hui-Hsuan, Chen, Jing-Hsien

Source: Plants (2223-7747); Dec2022, Vol. 11 Issue 23, p3357, 18p

Subject Terms: EAST Indian lotus, BIOMARKERS, WOUNDS & injuries, EPITHELIAL cells, KIDNEY physiology, CISPLATIN

Chemopreventive properties of Hibiscus sabdariffa L. on human gastric carcinoma cells through apoptosis induction and JNK/p38 MAPK signaling activation

Authors: Lin, Hui-Hsuan, Chen, Jing-Hsien, Kuo, Wu-Hsien, Wang, Chau-Jong

Source: In Chemico-Biological Interactions 2007 165(1):59-75

Autophagic effects of Hibiscus sabdariffa leaf polyphenols and epicatechin gallate (ECG) against oxidized LDL-induced injury of human endothelial cells.

Authors: Chen, Jing-Hsien¹, Lee, Ming-Shih, Wang, Chi-Ping, Hsu, Cheng-Chin¹, Lin, Hui-Hsuan linhh@csmu.edu.tw

Source: European Journal of Nutrition. Aug2017, Vol. 56 Issue 5, p1963-1981. 19p.

Subject Terms: *AUTOPHAGY, *ALTERNATIVE medicine, *APOPTOSIS, *BIOLOGICAL models, *CELL death, *CELLULAR signal transduction, *ENDOTHELIUM, *GENES, *HIBISCUS, *LOW density lipoproteins, *LIPID peroxidation (Biology), *POLYMERASE chain reaction, *POLYPHENOLS, *WESTERN immunoblotting, *PLANT extracts, *UMBILICAL arteries, *IN vitro studies