Integrating engineered nanomaterials with extracellular vesicles: advancing targeted drug delivery and biomedical applications

Authors: Hai Jiang, Ranil Vikraman Kumarasamy, JinJin Pei, Kamaraj Raju, Gopalakrishnan Velliyur Kanniappan, Chella Perumal Palanisamy, Ion Dan Mironescu

Source: Frontiers in Nanotechnology, Vol 6 (2025)

Subject Terms: engineered nanomaterials, extracellular vesicles, characterization, targeted drug delivery, biomedical applications, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnano.2024.1513683/full; https://doaj.org/toc/2673-3013

Access URL: https://doaj.org/article/2ce11cb00b5440c7ab7a96d0fbc73226

Exploring the anti-aging potential of natural products and plant extracts in budding yeast Saccharomyces cerevisiae: A review [version 2; peer review: 1 approved, 2 approved with reservations]

Authors: Madhu Dyavaiah, Chella Perumal Palanisamy, Tewin Tencomnao, Siriporn Chuchawankul, Phaniendra Alugoju, Naga Venkata Anusha Anthikapalli, Anchalee Prasanskulab, Selvaraj Jayaraman

Source: F1000Research, Vol 12 (2024)

Subject Terms: Saccharomyces cerevisiae, Replicative lifespan (RLS), Chronological lifespan (CLS), nutrient signalling pathways, target of rapamycin (TOR), Protein kinase A (PKA), eng, Medicine, Science

File Description: electronic resource

Relation: https://f1000research.com/articles/12-1265/v2; https://doaj.org/toc/2046-1402

Access URL: https://doaj.org/article/44bf79fe93b04655a0108d59f2c6df8d

Toward personalized cancer management: Role of precision nutrition–diet interventions

Authors: Hongfei Guo, Yvchen Liu, Tian Wan, Da Song, Chella Perumal Palanisamy, Jingzhang Geng, Jinjin Pei, Sevilay Özmen, A.M. Abd El-Aty

Source: Journal of Functional Foods, Vol 123, Iss , Pp 106584- (2024)

Subject Terms: Cancer treatment, Dietary strategies, Tumor metabolism, Clinical trials, Nutrition interventions, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464624005875; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/9b757a66ef0548ae87e7f409c98feac2

Molecular analysis to identify novel potential biomarkers as drug targets in colorectal cancer therapy: an integrated bioinformatics analysis

Authors: Mansour K. Gatasheh, Sathan Raj Natarajan, Rajapandiyan Krishnamoorthy, Tawfiq S Alsulami, Ponnulakshmi Rajagopal, Chella Perumal Palanisamy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman

Source: Molecular & Cellular Oncology, Vol 11, Iss 1 (2024)

Subject Terms: Colorectal cancer, bioinformatics analysis, therapeutic targets, differential gene expression, hub genes, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/2372-3556

Access URL: https://doaj.org/article/309e8a84a60242bb8f02e836d4fd92a0

Investigating the colon toxicity and carcinogenic role of monosodium glutamate compared with Dimethylhydrazine in male Wistar rats: Exploring the link to childhood colon cancer risk

Authors: Meenakshi Sundari Rajendran, Selvaraj Jayaraman, Javed Masood Khan, Sharmila Jasmine, RajKumar Prabhakaran, Manikandan Vani Raju, Meenakshi Kaniyur Chandrasekaran, Rathi Muthaiyan Ahalliya, Poornima Kannappan, Chella Perumal Palanisamy, Gopalakrishnan Velliyur Kanniappan

Source: Journal of King Saud University: Science, Vol 36, Iss 11, Pp 103507- (2024)

Subject Terms: Monosodium glutamate, Dimethylhydrazine, Colon cancer, Kaplan Meier Plot, Serum Biochemical parameters, β–Catenin, Science (General), Q1-390

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Relation: http://www.sciencedirect.com/science/article/pii/S1018364724004191; https://doaj.org/toc/1018-3647

Access URL: https://doaj.org/article/66774964956745c28944e07fcbe30058

Clinical applications and therapeutic potentials of advanced nanoparticles: a comprehensive review on completed human clinical trials

Authors: Ranil Vikraman Kumarasamy, Prabhu Manickam Natarajan, Vidhya Rekha Umapathy, Jeane Rebecca Roy, Monica Mironescu, Chella Perumal Palanisamy

Source: Frontiers in Nanotechnology, Vol 6 (2024)

Subject Terms: nanoparticles, nanomedicine, clinical trials, drug delivery, targeted therapy, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnano.2024.1479993/full; https://doaj.org/toc/2673-3013

Access URL: https://doaj.org/article/5f826e7ac64b4ba98eb61a4cb27bf9db

A comprehensive review of Cornus officinalis: health benefits, phytochemistry, and pharmacological effects for functional drug and food development

Authors: Wenhui Deng, Yuchen Liu, Yaodong Guo, Jie Chen, Hassan Idris Abdu, Muhmmad R. U. Khan, Chella Perumal Palanisamy, Jinjin Pei, A. M. Abd El-Aty

Source: Frontiers in Nutrition, Vol 10 (2024)

Subject Terms: Cornus officinalis, health characteristics, biological activity, pharmacological effects, Cornaceae, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2023.1309963/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/1512f373c49e4ddd8d87932d455aa41f

Formulation, characterization and evaluation of gelatin-syringic acid/zinc oxide nanocomposite for its effective anticancer, antioxidant and anti-inflammatory activities

Authors: M. Lavanya, Rajapandiyan Krishnamoorthy, Mohammad A. Alshuniaber, Salim Manoharadas, Chella Perumal Palanisamy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman, Ponnulakshmi Rajagopal, Ramakrishnan Padmini

Source: Journal of King Saud University: Science, Vol 35, Iss 8, Pp 102909- (2023)

Subject Terms: Zinc oxide nanoparticle, Syringic acid, Gelatin, Hep G2 cell line, Antioxidant, Anti-inflammatory, Science (General), Q1-390

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Relation: http://www.sciencedirect.com/science/article/pii/S1018364723003713; https://doaj.org/toc/1018-3647

Access URL: https://doaj.org/article/192256298b43467ba72baa89645b5848

Advancements in the Synthesis and Functionalization of Zinc Oxide-Based Nanomaterials for Enhanced Oral Cancer Therapy

Authors: Jinjin Pei, Prabhu Manickam Natarajan, Vidhya Rekha Umapathy, Bhuminathan Swamikannu, Nandini Manickam Sivaraman, Lakshmi Krishnasamy, Chella Perumal Palanisamy

Source: Molecules, Vol 29, Iss 11, p 2706 (2024)

Subject Terms: ZnO nanomaterials, synthesis methods, surface functionalization, oral cancer, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/11/2706; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/087338d7da1a4099bef2cec76666c1b9

Isolongifolene-loaded chitosan nanoparticles synthesis and characterization for cancer treatment

Authors: Dharmar Manimaran, Namasivayam Elangovan, Panagal Mani, Kumaran Subramanian, Daoud Ali, Saud Alarifi, Chella Perumal Palanisamy, Hongxia Zhang, Kowsalya Rangasamy, Vasan Palanisamy, Renuka Mani, Kavitha Govarthanan, Wilson Aruni, Rajeshkumar Shanmugam, Guru Prasad Srinivasan, Aruncahllam Kalirajan

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/96bd79ea80f345ffb5e3acb838a5640f

Nigella sativa L. seed extracts promote wound healing progress by activating VEGF and PDGF signaling pathways: An in vitro and in silico study [version 2; peer review: 2 approved, 2 approved with reservations]

Authors: Sirilux Poompradub, Chella Perumal Palanisamy, Selvaraj Jayaraman, Phaniendra Alugoju

Source: F1000Research, Vol 12 (2023)

Subject Terms: Nigella sativa L., Wound healing, Vascular endothelial growth factor, Platelet-derived growth factor, eng, Medicine, Science

File Description: electronic resource

Relation: https://f1000research.com/articles/12-436/v2; https://doaj.org/toc/2046-1402

Access URL: https://doaj.org/article/96348871213e44d3a6af5c386f714dcc

Nigella sativa L. seed extracts promote wound healing progress by activating VEGF and PDGF signaling pathways: An in vitro and in silico study [version 1; peer review: 2 approved, 1 approved with reservations]

Authors: Sirilux Poompradub, Chella Perumal Palanisamy, Selvaraj Jayaraman, Phaniendra Alugoju

Source: F1000Research, Vol 12 (2023)

Subject Terms: Nigella sativa L., Wound healing, Vascular endothelial growth factor, Platelet-derived growth factor, eng, Medicine, Science

File Description: electronic resource

Relation: https://f1000research.com/articles/12-436/v1; https://doaj.org/toc/2046-1402

Access URL: https://doaj.org/article/354547dbdcf94f50b4a3ce4f2c7f4d54

Beta-Sitosterol Facilitates GLUT4 Vesicle Fusion on the Plasma Membrane via the Activation of Rab/IRAP/Munc 18 Signaling Pathways in Diabetic Gastrocnemius Muscle of Adult Male Rats

Authors: JinJin Pei, Monisha Prasad, Ghada Mohamed Helal, Mohamed El-Sherbiny, Dalia Mahmoud Abdelmonem Elsherbini, Ponnulakshmi Rajagopal, Chella Perumal Palanisamy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman, Krishna Mohan Surapaneni

Source: Bioinorganic Chemistry and Applications, Vol 2022 (2022)

Subject Terms: Biotechnology, TP248.13-248.65, Inorganic chemistry, QD146-197

File Description: electronic resource

Relation: https://doaj.org/toc/1687-479X

Access URL: https://doaj.org/article/08d1e4a0f6104bffa4410c16780b4705

Computational Study on the Inhibitory Effect of Natural Compounds against the SARS-CoV-2 Proteins

Authors: John Marshal Jayaraj, Muralidharan Jothimani, Chella Perumal Palanisamy, Olli T. Pentikäinen, Mehboobali Pannipara, Abdullah G. Al-Sehemi, Karthikeyan Muthusamy, Krishnasamy Gopinath

Source: Bioinorganic Chemistry and Applications, Vol 2022 (2022)

Subject Terms: Biotechnology, TP248.13-248.65, Inorganic chemistry, QD146-197

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Relation: https://doaj.org/toc/1687-479X

Access URL: https://doaj.org/article/ca353293518c4e87bceffef27e67304d

(5E,7E)-4,5,6 Trihydroxy-3-(hydroxymethyl)tetrahydro-2H-pyran-2-ylheptadeca-5,7-dienoate from Euclea crispa (L.) Inhibits Ovarian Cancer Cell Growth by Controlling Apoptotic and Metastatic Signaling Mechanisms

Authors: Chella Perumal Palanisamy, Bo Cui, Hongxia Zhang, Selvaraj Jayaraman, Ponnulakshmi Rajagopal, Vishnu Priya Veeraraghavan

Source: Bioinorganic Chemistry and Applications, Vol 2022 (2022)

Subject Terms: Biotechnology, TP248.13-248.65, Inorganic chemistry, QD146-197

File Description: electronic resource

Relation: https://doaj.org/toc/1687-479X

Access URL: https://doaj.org/article/47f86133d96840e3b8eb03452c1f32a1

A Comprehensive Review on Bio-Based Materials for Chronic Diabetic Wounds

Authors: Jinjin Pei, Chella Perumal Palanisamy, Phaniendra Alugoju, Naga Venkata Anusha Anthikapalli, Prabhu Manickam Natarajan, Vidhya Rekha Umapathy, Bhuminathan Swamikannu, Selvaraj Jayaraman, Ponnulakshmi Rajagopal, Sirilux Poompradub

Source: Molecules, Vol 28, Iss 2, p 604 (2023)

Subject Terms: natural products, biomaterials, diabetic wounds, wound healing, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/2/604; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/ceedc1783c0c48d6b12ff01c7617021d

Screening of potential phytocompounds from Euclea crispa (Thunb.) leaves targeting human epidermal growth factor receptor 2 (HER2) signaling pathway

Authors: Chella Perumal Palanisamy, Anofi Omotayo Tom Ashafa

Source: Journal of Pharmacy and Bioallied Sciences, Vol 11, Iss 2, Pp 155-161 (2019)

Subject Terms: ADME properties, docking analysis, E. crispa, GC–MS analysis, HER2, Pharmacy and materia medica, RS1-441, Analytical chemistry, QD71-142

File Description: electronic resource

Relation: http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2019;volume=11;issue=2;spage=155;epage=161;aulast=Palanisamy; https://doaj.org/toc/0975-7406

Access URL: https://doaj.org/article/6ab5ebcd2e394b5aa1eeb8d696973fee

A Comprehensive Review on Therapeutic Perspectives of Phytosterols in Insulin Resistance: A Mechanistic Approach

Authors: Monisha Prasad, Selvaraj Jayaraman, Mohamed Ahmed Eladl, Mohamed El-Sherbiny, Mosaab Abdella Ebrahim Abdelrahman, Vishnu Priya Veeraraghavan, Srinivasan Vengadassalapathy, Vidhya Rekha Umapathy, Shazia Fathima Jaffer Hussain, Kalaiselvi Krishnamoorthy, Durairaj Sekar, Chella Perumal Palanisamy, Surapaneni Krishna Mohan, Ponnulakshmi Rajagopal

Source: Molecules, Vol 27, Iss 5, p 1595 (2022)

Subject Terms: phytosterols, insulin resistance, diabetes mellitus, obesity, cholesterol, therapeutic implications, Organic chemistry, QD241-441

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Relation: https://www.mdpi.com/1420-3049/27/5/1595; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/f957e6b0c702472cbe4d27601b55bd29

β-Sitosterol Circumvents Obesity Induced Inflammation and Insulin Resistance by down-Regulating IKKβ/NF-κB and JNK Signaling Pathway in Adipocytes of Type 2 Diabetic Rats

Authors: Selvaraj Jayaraman, Nalini Devarajan, Ponnulakshmi Rajagopal, Shyamaladevi Babu, Senthil Kumar Ganesan, Vishnu Priya Veeraraghavan, Chella Perumal Palanisamy, Bo Cui, Vijayalakshmi Periyasamy, Kirubhanand Chandrasekar

Source: Molecules, Vol 26, Iss 7, p 2101 (2021)

Subject Terms: adipokines, adipose tissue, inflammation, obesity, signaling pathways, type-2 diabetes, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/7/2101; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/c8f9f934881247de86f983621835e527

Proteomic insights uncover enhanced neurotherapeutic potential in conditioned mesenchymal stem cell-derived extracellular vesicles

Authors: Xi, Junxiu, Wang, Tian, Xian, Panpan, Liu, Xiaoyan, Du, Minghao, Yang, Hao, Chella, Perumal Palanisamy, Lin, Wei, Long, Qianfa

Source: In Extracellular Vesicle June 2024 3