Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk

Authors: Li, Ying, Chaurasia, Bhagirath, Rahman, M. Mahidur, Kaddai, Vincent, Maschek, J. Alan, Berg, Jordan A., Wilkerson, Joseph L., Mahmassani, Ziad S., Cox, James, Wei, Peng, Meikle, Peter J., Atkinson, Donald, Wang, Liping, Poss, Annelise M., Playdon, Mary C., Tippetts, Trevor S., Mousa, Esraa M., Nittayaboon, Kesara, Anandh Babu, Pon Velayutham, Drummond, Micah J., Clevers, Hans, Shayman, James A., Hirabayashi, Yoshio, Holland, William L., Rutter, Jared, Edgar, Bruce A., Summers, Scott A.

Source: In Gastroenterology November 2023 165(5):1136-1150

Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles

Authors: Jain, Raghav, Wade, Gina, Ong, Irene, Chaurasia, Bhagirath, Simcox, Judith

Source: In Journal of Lipid Research July 2022 63(7)

Ceramides are necessary and sufficient for diet-induced impairment of thermogenic adipocytes

Authors: Chaurasia, Bhagirath, Ying, Li, Talbot, Chad Lamar, Maschek, John Alan, Cox, James, Schuchman, Edward H., Hirabayashi, Yoshio, Holland, William L., Summers, Scott A.

Source: In Molecular Metabolism March 2021 45

Targeting a ceramide double bond improves insulin resistance and hepatic steatosis

Authors: Chaurasia, Bhagirath, Tippetts, Trevor S., Monibas, Rafael Mayoral, Liu, Jinqi, Li, Ying, Wang, Liping, Wilkerson, Joseph L., Sweeney, C. Rufus, Pereira, Renato Felipe, Sumida, Doris Hissako, Maschek, J. Alan, Cox, James E., Kaddai, Vincent, Lancaster, Graeme Iain, Siddique, Monowarul Mobin, Poss, Annelise, Pearson, Mackenzie, Satapati, Santhosh, Zhou, Heather, McLaren, David G., Previs, Stephen F., Chen, Ying, Qian, Ying, Petrov, Aleksandr, Wu, Margaret, Shen, Xiaolan, Yao, Jun, Nunes, Christian N., Howard, Andrew D., Wang, Liangsu, Erion, Mark D., Rutter, Jared, Holland, William L., Kelley, David E., Summers, Scott A.

Source: Science, 2019 Jul . 365(6451), 386-392.

Access URL: https://www.jstor.org/stable/26762285

Does This Schlank Make Me Look Fat?

Authors: Chaurasia, Bhagirath, Holland, William L., Summers, Scott A.

Source: In Trends in Endocrinology & Metabolism September 2018 29(9):597-599

Metabolic Messengers: ceramides

Authors: Summers, Scott A., Chaurasia, Bhagirath, Holland, William L.

Source: Nature metabolism. 1(11):1051-1058

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125164761.0x000001&indx=1&recIds=ETOCvdc_100125164761.0x000001

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

Authors: Kiser, Philip D., Kolesnikov, Alexander V., Kiser, Jianying Z., Dong, Zhiqian, Chaurasia, Bhagirath, Wang, Liping, Summers, Scott A., Hoang, Thanh, Blackshaw, Seth, Peachey, Neal S., Kefalov, Vladimir J., Palczewski, And Krzysztof

Source: FASEB journal. 33(4):5782-5792

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103323629.0x000001&indx=1&recIds=ETOCvdc_100103323629.0x000001

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

Authors: Chaurasia, Bhagirath, Kaddai, Vincent Andre, Lancaster, Graeme Iain, Henstridge, Darren C., Sriram, Sandhya, Galam, Dwight Lark Anolin, Gopalan, Venkatesh, Prakash, K.N. Bhanu, Velan, S. Sendhil, Bulchand, Sarada, Tsong, Teh Jing, Wang, Mei, Siddique, Monowarul Mobin, Yuguang, Guan, Sigmundsson, Kristmundur, Mellet, Natalie A., Weir, Jacquelyn M., Meikle, Peter J., Bin M. Yassin, M. Shabeer, Shabbir, Asim, Shayman, James A., Hirabayashi, Yoshio, Shiow, Sue-Anne Toh Ee, Sugii, Shigeki, Summers, Scott A.

Source: In Cell Metabolism 13 December 2016 24(6):820-834

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity

Authors: Jais, Alexander, Solas, Maite, Backes, Heiko, Chaurasia, Bhagirath, Kleinridders, André, Theurich, Sebastian, Mauer, Jan, Steculorum, Sophie M., Hampel, Brigitte, Goldau, Julia, Alber, Jens, Förster, Carola Y., Eming, Sabine A., Schwaninger, Markus, Ferrara, Napoleone, Karsenty, Gerard, Brüning, Jens C.

Source: In Cell 5 May 2016 165(4):882-895

Ceramides – Lipotoxic Inducers of Metabolic Disorders

Authors: Chaurasia, Bhagirath, Summers, Scott A.

Source: In Trends in Endocrinology & Metabolism October 2015 26(10):538-550

Dihydroceramides: From Bit Players to Lead Actors

Authors: Siddique, Monowarul Mobin ¹, Li, Ying, Chaurasia, Bhagirath, Kaddai, Vincent A., Summers, Scott A. ²

Source: In Journal of Biological Chemistry 19 June 2015 290(25):15371-15379

Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling

Authors: Buffolo, Márcio, Pires, Karla Maria, Ferhat, Maroua, Ilkun, Olesya, Makaju, Aman, Achenbach, Alan, Bowman, Faith, Atkinson, Donald L., Holland, William L., Amri, Ez-Zoubir, Chaurasia, Bhagirath, Franklin, Sarah, Boudina, Sihem

Source: Cell reports. 29(2):270-282.e5

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132791533.0x000001&indx=1&recIds=ETOCvdc_100132791533.0x000001

FOXN3 controls liver glucose metabolism by regulating gluconeogenic substrate selection

Authors: Karanth, Santhosh, Chaurasia, Bhagirath, Bowman, Faith M., Tippetts, Trevor S., Holland, William L., Summers, Scott A., Schlegel, Amnon

Source: Physiological reports. 7(18)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100089409342.0x000001&indx=1&recIds=ETOCvdc_100089409342.0x000001

Role of myeloid cells specific PDK-1 in inflammation and obesity induced insulin resistance

Authors: Chaurasia, Bhagirath

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_ZXVDPOJUDBRNB3A2SD5F3YAYN5APPNN7

Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk

Authors: Cai, Jinjin, Pires, Karla M., Ferhat, Maroua, Chaurasia, Bhagirath, Buffolo, Márcio A., Smalling, Rana, Sargsyan, Ashot, Atkinson, Donald L., Summers, Scott A., Graham, Timothy E., Boudina, Sihem

Source: Cell reports. 25(7):1708-1717.e5

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087885967.0x000001&indx=1&recIds=ETOCvdc_100087885967.0x000001

Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis.

Authors: Li, Ying, Talbot, Chad Lamar, Chandravanshi, Bhawna, Ksiazek, Alec, Sood, Ayushi, Chowdhury, Kamrul Hasan, Maschek, J. Alan, Cox, James, Babu, Adhini Kuppuswamy Satheesh, Paz, Henry A., Babu, Pon Velayutham Anandh, Meyerholz, David K., Wankhade, Umesh D., Holland, William, Shyong Tai, E., Summers, Scott A., Chaurasia, Bhagirath

Source: Scientific Reports; 5/4/2022, Vol. 12 Issue 1, p1-14, 14p

Subject Terms: FATTY liver, CORDYCEPS, FRUITING bodies (Fungi), INSULIN resistance, CERAMIDES, CLOSTRIDIUM acetobutylicum, CLOSTRIDIUM perfringens

Ceramides – Lipotoxic Inducers of Metabolic Disorders

Authors: Chaurasia, Bhagirath, Summers, Scott A.

Source: Trends in endocrinology and metabolism. 29(1):66-67

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129130033.0x000001&indx=1&recIds=ETOCvdc_100129130033.0x000001

Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.

Authors: Mauer, Jan¹, Chaurasia, Bhagirath², Goldau, Julia³, Vogt, Merly C⁴, Ruud, Johan⁴, Nguyen, Khoa D⁵, Theurich, Sebastian⁴, Hausen, A Christine⁴, Schmitz, Joel⁶, Brönneke, Hella S⁷, Estevez, Emma⁸, Allen, Tamara L⁸, Mesaros, Andrea⁹, Partridge, Linda⁹, Febbraio, Mark A⁸, Chawla, Ajay⁵, Wunderlich, F Thomas⁴, Brüning, Jens C¹⁰

Source: Nature Immunology. May2014, Vol. 15 Issue 5, p423-430. 8p.

Subject Terms: *CELLULAR signal transduction, *INTERLEUKIN-6, *MACROPHAGE activation, *ENDOTOXEMIA, *OBESITY, *INSULIN resistance, *INFLAMMATION

Ceramides in Metabolism: Key Lipotoxic Players.

Authors: Chaurasia, Bhagirath¹ (AUTHOR) bhagirath-chaurasia@uiowa.edu, Summers, Scott A.² (AUTHOR) scott.a.summers@health.utah.edu

Source: Annual Review of Physiology. 2/10/2021, Vol. 83 Issue 31, p303-330. 21p.

Adipocyte Ceramides—The Nexus of Inflammation and Metabolic Disease.

Authors: Chaurasia, Bhagirath, Talbot, Chad Lamar, Summers, Scott A.

Source: Frontiers in Immunology; 9/23/2020, Vol. 11, pN.PAG-N.PAG, 10p

Subject Terms: CERAMIDES, METABOLIC disorders, ADIPOSE tissue diseases, LIPID metabolism, ADIPOSE tissues, PROTEIN metabolism