Zanubrutinib in patients with previously treated B-cell malignancies intolerant of previous Bruton tyrosine kinase inhibitors in the USA: a phase 2, open-label, single-arm study

Authors: Shadman, Mazyar ^*, Flinn, Ian W, Levy, Moshe Y, Porter, Ryan F, Burke, John M, Zafar, Syed F, Misleh, Jamal, Kingsley, Edwin C, Yimer, Habte A, Freeman, Benjamin, Rao, Subramanya S, Chaudhry, Arvind, Tumula, Praveen K, Gandhi, Mitul D, Manda, Sudhir, Chen, Dih-Yih, By, Kunthel, Xu, Linlin, Liu, Ye, Crescenzo, Rocco, Idoine, Adam, Zhang, Xiaoping, Cohen, Aileen, Huang, Jane, Sharman, Jeff P

Source: In The Lancet Haematology January 2023 10(1):e35-e45

Pembrolizumab alone or combined with chemotherapy versus chemotherapy as first-line therapy for advanced urothelial carcinoma (KEYNOTE-361): a randomised, open-label, phase 3 trial

Authors: Cascallar, Diana Vera, Varela, Mirta, Lazzaro, Mauricio Fernandez, Kaen, Diego Lucas, Gatica, Gabriela, Flores, David Hugo, Falco, Agustin, Molina, Matias, Van Aelst, Filip, Vulsteke, Christof, Sautois, Brieuc, Machiels, Jean-Pascal, Schallier, Denis, Brust, Leandro, Rapatoni, Liane, Azevedo, Sergio J, Marinho, Gisele, Soares, Joao Paulo Holanda, Dzik, Carlos, Almeida Silva, Jamile, Fay, Andre Poisl, Gingerich, Joel, Fradet, Yves, Ferrario, Cristiano, Potvin, Kylea, Vanhuyse, Marie, Abdelsalam, Mahmoud, Cheng, Susanna, Caglevic, Christian, Reyes, Felipe, Leal, Jose Luis, Francisco, Francisco, Ibanez, Carolina, Joly, Florence, Laguerre, Brigitte, Ladoire, Sylvain, Flechon, Aude, Topart, Delphine, Huillard, Olivier, Oudard, Stéphane, Gross-Goupil, Marine, Culine, Stephane, Loriot, Yohann, Gravis, Gwenaelle, Reichardt, Peter, Retz, Margitta, Herden, Jan, Pfister, David, Ohlman, Carsten, Stoeckle, Michael, Wirth, Manfred, Lorch, Anja, Niegisch, Guenter, Goebell, Peter J, Boegemann, Martin, Merseburger, Axel, Gakis, Georgios, Bedke, Jens, Neisius, Andreas, Thomas, Christian, Hoefner, Thomas, Telekes, Andras, Kosa, Judit Erzsebet, Revesz, Janos, Bodoky, Gyorgy, Csoszi, Tibor, Csejtei, Andras, Geczi, Lajos, Ruzsa, Agnes, Kolonics, Zsuzsanna, Erfan, Jozsef, McDermott, Ray, Bambury, Richard, Sella, Avishay, Frank, Stephen Jay, Kejzman, Daniel, Goldman, Olesya, Rosenbaum, Eli, Peer, Avivit, Berger, Raanan, Rouvinov, Keren, Sarid, David, Fukasawa, Satoshi, Arai, Gaku, Yamaguchi, Akito, Yokomizo, Akira, Takayama, Tatsuya, Kinoshita, Hidefumi, Kikuchi, Eiji, Mizuno, Ryuichi, Fujii, Yasuhisa, Sassa, Naoto, Matsukawa, Yoshihisa, Fujimoto, Kiyohide, Matsubara, Nobuaki, Tanikawa, Toshiki, Tomita, Yoshihiko, Nishimura, Kazuo, Tsujihata, Masao, Oyama, Masafumi, Masumori, Naoya, Kanayama, Hiroomi, Takano, Toshimi, Miura, Yuji, Miyazaki, Jun, Joraku, Akira, Kimura, Tomokazu, Yamamoto, Yoshiaki, Kobayashi, Kazuki, De Wit, Ronald, Aarts, Maureen, Gerritsen, Winald, Los, Maartje, Beerepoot, Laurens, Izmailov, Adel, Gorelov, Sergey Igorevich, Alekseev, Boris Yakovlevich, Semenov, Andrey, Kostorov, Vladimir Anatolyevich, Alekseev, Sergey M, Zyryanov, Alexander, Oschepkov, Vasiliy Nikolaevich, Shidin, Vladimir Aleksandrovich, Vladimirov, Vladimir Ivanovich, Gafanov, Rustem Airatovich, Karlov, Petr Alexandrovich, Anderson, David Brian, Shepherd, Lucinda, Cohen, Graham Lawrence, Rapoport, Bernardo Louis, Ruff, Paul, Lee, Nari, Bae, Woo Kyun, Lee, Hyo Jin, Herranz, Urbano Anido, Rodriguez-Vida, Alejo, Morales Barrera, Rafael, Grande, Enrique, Alonso Gordoa, Teresa, Guma Padro, Josep, Gauna, Daniel Castellano, Arranz, Jose Angel, Munoz Langa, Jose, Sarrio, Regina Girones, Montesa Pino, Alvaro, Juan Fita, Maria Jose, Su, Yu-Li, Lin, Yung-Chang, Su, Wen-Pin, Shen, Ying-Chun, Chang, Yen-Hwa, Huang, Yi-Hsiu, Sriuranpong, Virote, Chansriwong, Phichai, Srimuninnimit, Vichien, Danchaivijitr, Pongwut, Abali, Huseyin, Yavuz, Sinan, Ozyilkan, Ozgur, Sendur, Mehmet Ali Nahit, Ekenel, Meltem, Ozguroglu, Mustafa, Arslan, Cagatay, Gunduz, Seyda, Ozdogan, Mustafa, Birtle, Alison, Powles, Thomas, Huddart, Robert, de Santis, Maria, Zarkar, Anjali, Evans, Linda, Hussain, Syed, DiSimone, Christopher, Muina, Antonio F, Schlegel, Peter, Jhangiani, Haresh S, Harrison, Michael, Slater, Dennis E, Wright, David, Percent, Ivor J, Lin, Jianqing, Hwang, Clara, Mamtani, Ronac, Gupta, Sumati, Bajaj, Madhuri, Galamaga, Robert, Eklund, John, Wallace, James, Shtivelband, Mikhail, Suh, Jason Jung-Gon, Burhani, Nafisa, Eadens, Matthew, Gunturu, Krishna, Burgess, Earle, Wong, John, Chaudhry, Arvind, Van Veldhuizen, Peter, Graff, Stephanie, Thomas, Christian A, Schnadig, Ian D, Carneiro, Benedito, Hussain, Maha, Morgans, Alicia, Fitzharris, John T, Oliff, Ira A, Vuky, Jacqueline, Hauke, Ralph, Baron, Ari, Joshi, Monika, Bolemon, Britt H, Jiang, Peter, Mega, Anthony E, Markus, Maurice, Pfanzelter, Nicklas, Lawler, William Eyre, Cobb, Patrick Wayne, Courtright, Jay G, Jain, Sharad, Doshi, Gurjyot, Gunuganti, Vijay K, Sartor, Oliver Alton, Cole, Scott W, Babiker, Hani, Uchio, Edward M, Drakaki, Alexandra, Mannuel, Heather D, Alva, Ajjai, Guancial, Elizabeth, Fung, Chunkit, Charles, Anthony, Amato, Robert J, Arriaga, Yull, Bowman, Isaac, Ades, Steven, Dreicer, Robert, Yu, Evan, Quinn, David I, Fleming, Mark, Csőszi, Tibor, Özgüroğlu, Mustafa, Géczi, Lajos, Cheng, Susanna Y-S, Oudard, Stephane, Fléchon, Aude, Yu, Evan Y, Nam, Kijoeng, Imai, Kentaro, Homet Moreno, Blanca

Source: In The Lancet Oncology July 2021 22(7):931-945

Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial

Authors: Abildgaard, Niels, Adler, Howard, Altuntas, Fevzi, Akay, Olga Meltem, Amin, Bipinkumar, Anagnostopoulos, Achilleas, Anderson, Larry, Anttila, Pekka, Araujo, Carla, Arce-Lara, Carlos, Aydin, Yildiz, Basu, Supratik, Battini, Ramakrishna, Beeker, Thaddeus, Benboubker, Lotfi, Ben-Yehuda, Dina, Bladé, Joan, Blau, Igor Wolfgang, Boccia, Ralph, Burke, Lillian, Byeff, Peter, Cascavilla, Nicola, Cavo, Michele, Chantry, Andrew, Charles, Yen, Chaudhry, Arvind, Corso, Alessandro, Coyne, Mark, De Arriba, Felipe, Delimpasi, Sosana, Desjardins, Pierre, Dhakal, Binod, Di Bartolomeo, Paolo, Di Raimondo, Francesco, Dürig, Jan, Engelhardt, Monika, Escoffre-Barbe, Martine, Esteves, Graca, Flogegard, Max, Gabrail, Nashat, Gamberi, Barbara, Garrison, Mitchell, Gay, Julie, Gisslinger, Heinz, Goldschmidt, Hartmut, Goncalves, Cristina, Gressot, Laurent, Grosicki, Sebastian, Hanna, Wahid, Hayden, Patrick, Henriques Bernardo, Maria Manuela, Hermann, Robert, Holden, Viran, Honkalehto, Kirsti, Huben, Marianne, Huffman, John, Hunter, Hannah, Hus, Marek, Jagasia, Madan, Jagganath, Sundar, Janakiram, Murali, Jaiyesimi, Ishmael, Jenner, Matthew, João, Cristina, Johnson, Peter, Jurcyszyn, Artur, Kalayoğlu Beşişik, Sevgi, Kambhampati, Suman, Kanate, Abraham, Karadoğan, Ihsan, Khojasteh, Ali, Kirkel, Dean, Komarnicki, Mieczyslaw, Krauth, Maria-Theresa, Kuriakose, Phillip, Larocca, Alessandra, Lauri, Birgitta, Leleu, Xavier, Lucio, Paulo, Luppi, Mario, Mangiacavalli, Silvia, Mariette, Clara, Matsue, Kosei, Mellqvist, Ulf-Henri, Mendeleeva, Larisa, Meshad, Michael, Miller, Carole, Mohrbacher, Ann, Moreau, Philippe, Morelli, Anna Maria, Müldür, Ercan, Naassan, Anthony, Nahi, Hareth, Nair, Rajesh, O'Dwyer, Mike, Öngören Aydin, Seniz, Openshaw, Thomas, O'Rourke, Timothy, Osswald, Michael, Overton, Lindsay, Pati, Asmin, Pavic, Michel, Pegourie, Brigitte, Pehlivan, Mustafa, Pierola, Ana Alfonso, Plesner, Torben, Pluta, Andrzej, Rabin, Neil, Ramasamy, Karthik, Rambaldi, Alessandro, Rodriguez, Paula, Röllig, Christoph, Rosenblatt, Jacalyn, Rosenbluth, Jonathan, Salomo, Morten, Samoylova, Olga, Sastre Moral, Jose, Sati, Hamdi, Selleri, Carmine, Shafeek, Salim, Shinagawa, Atsushi, Sleckman, Bethany, Smith, Clay, Sonmez, Mehmet, Stone, Chester, Streetly, Matthew, Suzuki, Kenshi, Taetle, Raymond, Tafuri, Agostino, Takezako, Naoki, Teke, Hava Üsküdar, Vapaatalo, Mirja, Vassilopoulos, George, Verma, Amit, Vidito, Sarah, Viterbo, Luisa, Vural, Filiz, Wang, Xiang Sean, Yağci, Munci, Yee, Andrew, Richardson, Paul G, Oriol, Albert, Beksac, Meral, Liberati, Anna Marina, Galli, Monica, Schjesvold, Fredrik, Lindsay, Jindriska, Weisel, Katja, White, Darrell, Facon, Thierry, San Miguel, Jesus, Sunami, Kazutaka, O'Gorman, Peter, Sonneveld, Pieter, Robak, Pawel, Semochkin, Sergey, Schey, Steve, Yu, Xin, Doerr, Thomas, Bensmaine, Amine, Biyukov, Tsvetan, Peluso, Teresa, Zaki, Mohamed, Anderson, Kenneth, Dimopoulos, Meletios

Source: In The Lancet Oncology June 2019 20(6):781-794

Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study

Authors: Acosta-Rivera, Mirelis, Adkins, Douglas R., Aghmesheh, Morteza, Ahn, Myung-Ju, Airoldi, Mario, Aleknavicius, Eduardas, Al-Farhat, Yousuf, Algazi, Alain P., Almokadem, Salah, Alyasova, Anna, Bauman, Jessica R., Benasso, Marco, Berrocal, Alfonso, Bray, Victoria, Burtness, Barbara Ann, Caponigro, Francesco, Castro, Ana, Cescon, Terrence P., Chan, Kelvin, Chaudhry, Arvind, Chauffert, Bruno, Cohen, Ezra, Csoszi, Tibor, De Boer, J.P., Delord, Jean-Pierre, Dietz, Andreas, Dinis, Jose, Dupuis, Charlotte, Digue, Laurence, Erfan, Jozsef, Escobar Alvarez, Yolanda, Evans, Mererid, Fidler, Mary Jo, Forster, Martin David, Friesland, Signe, Ganti, Apar K., Geoffrois, Lionnel, Grant, Cliona, Gruenwald, Viktor, Harrington, Kevin, Hoffmann, Thomas, Horvai, Geza, Inciura, Arturas, Jang, Raymond, Jankowska, Petra, Jimeno, Antonio, Joseph, Mano, Juarez Ramiro, Alejandro, Karaszewska, Boguslawa, Kawecki, Andrzej, Keilholz, Ulrich, Keller, Ulrich, Kim, Sung-Bae, Kocsis, Judit, Kotecki, Nuria, Kozloff, Mark F., Lambea, Julio, Landherr, Laszlo, Lantsukhay, Yuri, Lazarev, Sergey Alexandrovich, Lee, Lip Way, Le Tourneau, Christophe, Licitra, Lisa, Lifirenko, Igor Dmitrievich, Mach, Nicolas, Martincic, Danko, Matorin, Oleg Vladmirovhich, McGrath, Margaret, Machiels, Jean-Pascal, Mehra, Ranee, Misiukiewicz, Krzysztof, Morris, John C., Mufazalov, Fagim Fanisovich, Niu, Jiaxin, Pamoorthy Srinivasan, Devraj, Perez Segura, Pedro, Rauch, Daniel, Ribeiro, Maria Leonor, Rodriguez, Cristina, Rolland, Frederic, Russo, Antonio, Ruzsa, Agnes, Sanches, Frederico, Shin, Sang-Won, Shtiveland, Mikhail, Soulieres, Denis, Soria, Ainara, Specenier, Pol, Szekanecz, Eva, Szota, Judit, van Herpen, Carla M.L., Velez-Cortes, Hector A., Walsh, William V., Wilop, Stefan, Winterhalder, Ralph, Wojtukiewicz, Marek, Wong, Deborah, Zandberg, Dan, Cohen, Ezra E W, Soulières, Denis, Dinis, José, Burtness, Barbara, Zhang, Pingye, Cheng, Jonathan, Swaby, Ramona F, Harrington, Kevin J

Source: In The Lancet 12-18 January 2019 393(10167):156-167

Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study

Authors: Paz-Ares Rodriguez, Luis, Novello, Silvia, Hiret, Sandrine, Schmid, Peter, Laack, Eckart, Califano, Raffaele, Maemondo, Makoto, Kim, Sang-We, Chaft, Jamie, Vicente Baz, David, Berghmans, Thierry, Kim, Dong-Wan, Surmont, Veerle, Reck, Martin, Han, Ji-Youn, Holgado Martin, Esther, Belda Iniesta, Cristobal, Oe, Yuichiro, Chella, Antonio, Chopra, Akhil, Robinet, Gilles, Soto Parra, Hector, Thomas, Michael, Cheema, Parneet, Katakami, Nobuyuki, Su, Wu-Chou, Kim, Young-Chul, Wolf, Juergen, Lee, Jong-Seok, Saka, Hideo, Milella, Michele, Ramos Garcia, Inmaculada, Sibille, Anne, Yokoi, Takashi, Kang, Eun Joo, Atagi, Shinji, Spaeth-Schwalbe, Ernst, Nishio, Makoto, Imamura, Fumio, Gabrail, Nashat, Veillon, Remi, Derijcke, Sofie, Maeda, Tadashi, Zylla, Dylan, Kubiak, Kendra, Santoro, Armando, Uy, Ma. Noemi, Lucien Geater, Sarayut, Italiano, Antoine, Kowalski, Dariusz, Barlesi, Fabrice, Chen, Yuh-Min, Spigel, David, Chewaskulyong, Busyamas, Garcia Gomez, Ramon, Alvarez Alvarez, Rosa, Yang, Chih-Hsin, Hsia, Te-Chun, Denis, Fabrice, Sakai, Hiroshi, Vincent, Mark, Goto, Koichi, Bosch-Barrera, Joaquim, Weiss, Glen, Canon, Jean-Luc, Scholz, Christian, Aglietta, Massimo, Kemmotsu, Hirotsugu, Azuma, Koichi, Bradbury, Penelope, Feld, Ronald, Chachoua, Abraham, Jassem, Jacek, Juergens, Rosalyn, Palmero Sanchez, Ramon, Malcolm, Albert, Vrindavanam, Nandagopal, Kubota, Kaoru, Waller, Cornelius, Waterhouse, David, Coudert, Bruno, Mark, Zsuzsanna, Satouchi, Miyako, Chang, Gee-Chen, Herzmann, Christian, Chaudhry, Arvind, Giridharan, Selvaraj, Hesketh, Paul, Ikeda, Norihiko, Boccia, Ralph, Iannotti, Nichola, Haigentz, Missak, Reynolds, John, Querol, John, Nakagawa, Kazuhiko, Sugawara, Shunichi, Tan, Eng Huat, Hirashima, Tomonori, Gettinger, Scott, Kato, Terufumi, Takeda, Koji, Juan Vidal, Oscar, Mohn-Staudner, Andrea, Panwalkar, Amit, Daniel, Davey, Kobayashi, Kunihiko, Ladrera, Guia Elena Imelda, Schulte, Clemens, Sebastian, Martin, Cernovska, Marketa, Coupkova, Helena, Havel, Libor, Pauk, Norbert, Singh, Joginder, Murakami, Shuji, Csoszi, Tibor, Losonczy, Gyorgy, Price, Allan, Anderson, Ian, Iqbal, Mussawar, Torri, Vamsee, Juhasz, Erzsebet, Khanani, Saleem, Koubkova, Leona, Levy, Benjamin, Page, Ray, Bocskei, Csaba, Crinò, Lucio, Einspahr, David, Hagenstad, Christopher, Juat, Necy, Overton, Lindsay, Garrison, Mitchell, Szalai, Zsuzsanna, Garassino, Marina Chiara, Cho, Byoung-Chul, Kim, Joo-Hang, Mazières, Julien, Vansteenkiste, Johan, Lena, Hervé, Corral Jaime, Jesus, Gray, Jhanelle E, Powderly, John, Chouaid, Christos, Bidoli, Paolo, Wheatley-Price, Paul, Park, Keunchil, Soo, Ross A, Huang, Yifan, Wadsworth, Catherine, Dennis, Phillip A, Rizvi, Naiyer A

Source: In The Lancet Oncology April 2018 19(4):521-536

Derazantinib alone and with atezolizumab in metastatic urothelial carcinoma with activating FGFR aberrations.

Authors: Necchi, Andrea, Ramlau, Rodryg, González, Alejandro Falcón, Chaudhry, Arvind, Todenhöfer, Tilman, Tahbaz, Rana, Fontana, Elisa, Giannatempo, Patrizia, Deville, Jean-Laurent, Pouessel, Damien, Yoon, Shinkyo, Powles, Thomas, Bernat, Mathieu, Häckl, Manuel, Marszewska, Michalina, McKernan, Phil, Saulay, Mikael, Scaleia, Federica, Engelhardt, Marc, Loriot, Yohann

Source: JNCI Cancer Spectrum; Jun2024, Vol. 8 Issue 3, p1-10, 10p

Subject Terms: KINASE inhibitors, TRANSITIONAL cell carcinoma, FIBROBLAST growth factor receptors

A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma

Authors: Bowles, Daniel W., Kochenderfer, Mark, Cohn, Allen, Sideris, Lucas, Nguyen, Nghia, Cline-Burkhardt, Vivian, Schnadig, Ian, Choi, Minsig, Nabell, Lisle, Chaudhry, Arvind, Ruxer, Robert, Ucar, Antonio, Hausman, Diana, Walker, Luke, Spira, Alexander, Jimeno, Antonio

Source: In Clinical Colorectal Cancer December 2016 15(4):337-344

Genomic Characterization of Patients in a Phase 2 Study of Zanubrutinib in BTK Inhibitor-Intolerant Patients with Relapsed/Refractory B-Cell Malignancies

Authors: Xu, Linlin ^*, Shadman, Mazyar, Ponakala, Anusha ^*, Flinn, Ian W., Levy, Moshe Yair, Porter, Ryan ^*, Burke, John M., Zafar, Syed F., Cultrera, Jennifer L. ^*, Misleh, Jamal ^*, Kingsley, Edwin C., Yimer, Habte, Freeman, Benjamin ^*, Chaudhry, Arvind ^*, Tumula, Praveen K. ^*, Gandhi, Mitul, Cohen, Aileen ^*, Chen, Dih-Yih ^*, Manda, Sudhir, Sharman, Jeff P., Ramakrishnan, Vanitha ^*

Source: In Blood 15 November 2022 140 Supplement 1:9269-9271

Zanubrutinib in Acalabrutinib-Intolerant Patients (Pts) with B-Cell Malignancies

Authors: Shadman, Mazyar, Flinn, Ian W., Kingsley, Edwin C., Freeman, Benjamin ^*, Levy, Moshe Yair, Holmes, Houston ^*, Farber, Charles M., Chaudhry, Arvind ^*, Crescenzo, Rocco ^*, Idoine, Adam ^*, Zhang, Xiaoping ^*, Cohen, Aileen ^*, By, Kunthel ^*, Huang, Jane ^*, Sharman, Jeff P.

Source: In Blood 15 November 2022 140 Supplement 1:3655-3657

XMT-1660: A phase I, first-in-human trial of a B7-H4-directed dolasynthen antibody-drug conjugate in ovarian, endometrial, and breast cancers

Authors: Burger, Robert ^a, Hamilton, Erika ^b, Adams, Sylvia ^c, Han, Hyo ^d, Spira, Alexander ^e, Giordano, Antonio ^f, Chaudhry, Arvind ^g, Parajuli, Ritesh ^h, Wang, Judy ⁱ, Weise, Amy ^j, Abuhadra, Nour ^k, McNamara, Patrick ^a, Kalinsky, Kevin ^l

Source: In Gynecologic Oncology November 2024 190 Supplement 1:S282-S282

CLL-415 Phase 3 BELLWAVE-010: Nemtabrutinib Plus Venetoclax Versus Venetoclax Plus Rituximab (VR) in Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Authors: Lavie, David, Ozcan, Muhit, Chaudhry, Arvind, Zhou, Xuan, Paydar, Ima, Farooqui, Mohammed Z.H., Ghia, Paolo

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2024 24 Supplement 1:S353-S353

CLL-414 Phase 3 BELLWAVE-011 Study: Nemtabrutinib Versus Ibrutinib or Acalabrutinib in Previously Untreated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Authors: Tadmor, Tamar, Eyre, Toby A., Benjamini, Ohad, Chaudhry, Arvind, Shen, Juan, Leng, Siyang, Farooqui, Mohammed, Lavie, David

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2024 24 Supplement 1:S352-S353

Phase 3 BELLWAVE-010: Nemtabrutinib Plus Venetoclax Versus Venetoclax Plus Rituximab (VR) in Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Authors: Lavie, David, Ozcan, Muhit, Chaudhry, Arvind, Zhou, Xuan, Paydar, Ima, Farooqui, Mohammed Z.H., Ghia, Paolo

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2024 24 Supplement 1:S182-S182

Phase 3 BELLWAVE-011 Study: Nemtabrutinib Versus Ibrutinib or Acalabrutinib in Previously Untreated Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL)

Authors: Tadmor, Tamar, Eyre, Toby A., Benjamini, Ohad, Chaudhry, Arvind, Shen, Juan, Leng, Siyang, Farooqui, Mohammed, Lavie, David

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2024 24 Supplement 1:S182-S182

Genomic Landscape of Ibrutinib- and/or Acalabrutinib-intolerant Patients with B-cell Malignancies Treated with Zanubrutinib in a Phase 2 Study

Authors: Xu, Linlin, Shadman, Mazyar, Flinn, Ian W., Levy, Moshe, Porter, Ryan, Burke, John M., Zafar, Syed F., Cultrera, Jennifer L., Misleh, Jamal, Kingsley, Edwin C., Yimer, Habte A., Freeman, Benjamin B., Chaudhry, Arvind, Tumula, Praveen K., Gandhi, Mitul, Crescenzo, Rocco J., By, Kunthel, Cohen, Aileen Cleary, Idoine, Adam, Manda, Sudhir, Sharman, Jeff P.

Source: In Blood 2 November 2023 142 Supplement 1:6510-6510

Bellwave-010: Phase 3, Open-Label, Randomized Study of Nemtabrutinib Plus Venetoclax Versus Venetoclax Plus Rituximab in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Following at Least One Prior Therapy

Authors: Lavie, David, Ozcan, Muhit, Chaudhry, Arvind, Zhou, Xuan, Paydar, Ima, Farooqui, Mohammed Z.H., Ghia, Paolo

Source: In Blood 2 November 2023 142 Supplement 1:3287-3287

XMT-1660: A Phase 1b trial of a B7-H4 targeting antibody drug conjugate (ADC) in endometrial, ovarian, and breast cancers (1250)

Authors: Hamilton, Erika, Spira, Alexander, Adams, Sylvia, Abuhadra, Nour, Giordano, Antonio, Parajuli, Ritesh, Han, Hyo, Weise, Amy, Marchesani, Aubri, Josephs, Kate, Chaudhry, Arvind, Kalinsky, Kevin

Source: In Gynecologic Oncology September 2023 176 Supplement 1:S158-S158

Phase 2 Study of Zanubrutinib in BTK Inhibitor-Intolerant Patients (Pts) with Relapsed/Refractory B-Cell Malignancies

Authors: Shadman, Mazyar, Flinn, Ian W., Levy, Moshe Y., Porter, Ryan, Burke, John M., Cultrera, Jennifer L., Misleh, Jamal, Zafar, Syed F., Freeman, Benjamin, Rao, Subramanya S., Yimer, Habte, Chaudhry, Arvind, Gandhi, Mitul D., Guthrie, Troy H., Kingsley, Edwin, Tumula, Praveen K., Manda, Sudhir, Chen, Dih-Yih, Cohen, Aileen, By, Kunthel, Xu, Linlin, Liu, Ye, Sharman, Jeff P.

Source: In Blood 23 November 2021 138 Supplement 1:1410-1410

This result is not displayed to guests.
Login for full access.

waveLINE-006: A phase 2 study of the safety and efficacy of zilovertamab vedotin as monotherapy or in combination in patients (pts) with aggressive and indolent B-cell malignancies.

Authors: Zinzani, Pier Luigi¹ (AUTHOR), Mayer, Jiri² (AUTHOR), Benjamini, Ohad³ (AUTHOR), Berkovits, Alejandro⁴ (AUTHOR), Glimelius, Ingrid⁵ (AUTHOR), Stevens, Don A.⁶ (AUTHOR), Chaudhry, Arvind⁷ (AUTHOR), Muzaffer Demir, Ahmet⁸ (AUTHOR), Garcia Sanz, Ramón⁹ (AUTHOR), Seog Kim, Won¹⁰ (AUTHOR), Li, Fei¹¹ (AUTHOR), Halka, Janusz¹² (AUTHOR), Marin-Niebla, Ana¹³ (AUTHOR), Ozcan, Muhit¹⁴ (AUTHOR), Paszkiewicz-Kozik, Ewa¹⁵ (AUTHOR), Santoro, Armando¹⁶ (AUTHOR), Ren, Yixin¹⁷ (AUTHOR), Ogbu, Uzor¹⁷ (AUTHOR), Marinello, Patricia¹⁷ (AUTHOR), Jurczak, Wojciech¹⁸ (AUTHOR)

Source: Journal of Clinical Oncology. 2023 Supplement 16, Vol. 41, pTPS7595-TPS7595. 1p.