Immunogenicity of COVID-19 vaccines and their effect on HIV reservoir in older people with HIV

Authors: Matveev, Vitaliy A., Mihelic, Erik Z., Benko, Erika, Budylowski, Patrick, Grocott, Sebastian, Lee, Terry, Korosec, Chapin S., Colwill, Karen, Stephenson, Henry, Law, Ryan, Ward, Lesley A., Sheikh-Mohamed, Salma, Mailhot, Geneviève, Delgado-Brand, Melanie, Pasculescu, Adrian, Wang, Jenny H., Qi, Freda, Tursun, Tulunay, Kardava, Lela, Chau, Serena, Samaan, Philip, Imran, Annam, Copertino, Dennis C., Jr., Chao, Gary, Choi, Yoojin, Reinhard, Robert J., Kaul, Rupert, Heffernan, Jane M., Jones, R. Brad, Chun, Tae-Wook, Moir, Susan, Singer, Joel, Gommerman, Jennifer, Gingras, Anne-Claude, Kovacs, Colin, Ostrowski, Mario

Source: In iScience 20 October 2023 26(10)

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mRNA vaccine-induced SARS-CoV-2 spike-specific IFN-γ and IL-2 T-cell responses are predictive of serological neutralization and are transiently enhanced by pre-existing cross-reactive immunity.

Authors: Samaan, Philip¹, Korosec, Chapin S.^2,3, Budylowski, Patrick^4,5, Chau, Serena L. L.⁵, Pasculescu, Adrian⁶, Qi, Freda⁶, DelgadoBrand, Melanie⁶, Tursun, Tulunay R.⁶, Mailhot, Geneviève⁶, Dayam, Roya Monica⁶, Arnold, Corey R.⁷, Langlois, Marc-André⁷, Mendoza, Justin⁵, Morningstar, Thomas⁵, Law, Ryan⁵, Mihelic, Erik⁵, Sheikh-Mohamed, Salma⁸, Cao, Eric Yixiao⁸, Paul, Nimitha⁹, Patel, Anjali⁹

Source: Journal of Virology. Mar2025, Vol. 99 Issue 3, p1-28. 28p.

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