Exploiting three-dimensional human hepatic constructs to investigate the impact of rs174537 on fatty acid metabolism.

Authors: L Madison Kirk, Charlotte Mae K Waits, Alexander C Bashore, Beverly Dosso, Allison K Meyers, Antonio C Renaldo, Thomas J DePalma, Kelli N Simms, Nathaniel Hauser, Chia-Chi Chuang Key, Charles E McCall, John S Parks, Susan Sergeant, Carl D Langefeld, Aleksander Skardal, Elaheh Rahbar

Source: PLoS ONE, Vol 17, Iss 1, p e0262173 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f2c6eac11b404b5b9fab58864eb69f57

Contrasting effects of Western vs Mediterranean diets on monocyte inflammatory gene expression and social behavior in a primate model

Authors: Corbin SC Johnson, Carol A Shively, Kristofer T Michalson, Amanda J Lea, Ryne J DeBo, Timothy D Howard, Gregory A Hawkins, Susan E Appt, Yongmei Liu, Charles E McCall, David M Herrington, Edward H Ip, Thomas C Register, Noah Snyder-Mackler

Source: eLife, Vol 10 (2021)

Subject Terms: Macaca fascicularis, evolutionary mismatch, diet, monocyte, behavior, gene regulation, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/68293; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/ab97584b0c994536be61419945f11ac6

Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

Authors: Rabina Mainali, Manal Zabalawi, David Long, Nancy Buechler, Ellen Quillen, Chia-Chi Key, Xuewei Zhu, John S Parks, Cristina Furdui, Peter W Stacpoole, Jennifer Martinez, Charles E McCall, Matthew A Quinn

Source: eLife, Vol 10 (2021)

Subject Terms: sepsis, liver, inflammation, metabolism, steatosis, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/64611; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/54dd853ae26241009d6cb06d0d6d3a95

Epigenetic and metabolic programming of innate immunity in sepsis

Authors: Vidula Vachharajani, Charles E McCall

Source: Innate Immunity, Vol 25 (2019)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1753-4259; https://doaj.org/toc/1753-4267

Access URL: https://doaj.org/article/5efaf494a43b4fe89c79cff9a0396973

Correction: Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.

Authors: Xianfeng Wang, Nancy L Buechler, Ayana Martin, Jonathan Wells, Barbara Yoza, Charles E McCall, Vidula Vachharajani

Source: PLoS ONE, Vol 11, Iss 9, p e0162560 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5008694?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f4019b525ba245af8a556f778d97ca40

Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.

Authors: Xianfeng Wang, Nancy L Buechler, Ayana Martin, Jonathan Wells, Barbara Yoza, Charles E McCall, Vidula Vachharajani

Source: PLoS ONE, Vol 11, Iss 8, p e0160431 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4976857?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8e294c943f174df684a956a65e2c53c4

Assembly of inflammation-related genes for pathway-focused genetic analysis.

Authors: Matthew J Loza, Charles E McCall, Liwu Li, William B Isaacs, Jianfeng Xu, Bao-Li Chang

Source: PLoS ONE, Vol 2, Iss 10, p e1035 (2007)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2001184?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3bb39516477c42fba94a42c1a1015289

Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice

Authors: Ayana N. Martin, Martha Alexander-Miller, Barbara K. Yoza, Vidula Vachharajani, Charles E. McCall

Source: Journal of Immunology Research, Vol 2018 (2018)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2314-8861; https://doaj.org/toc/2314-7156

Access URL: https://doaj.org/article/7cab411e22c44c0d81a75d1a5d29bdfe

Sirtuin 2 Regulates Microvascular Inflammation during Sepsis

Authors: Nancy Buechler, Xianfeng Wang, Barbara K. Yoza, Charles E. McCall, Vidula Vachharajani

Source: Journal of Immunology Research, Vol 2017 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2314-8861; https://doaj.org/toc/2314-7156

Access URL: https://doaj.org/article/2b13b580aad54224a672dcc67e65b43c

Sirtuins Link Inflammation and Metabolism

Authors: Vidula T. Vachharajani, Tiefu Liu, Xianfeng Wang, Jason J. Hoth, Barbara K. Yoza, Charles E. McCall

Source: Journal of Immunology Research, Vol 2016 (2016)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2314-8861; https://doaj.org/toc/2314-7156

Access URL: https://doaj.org/article/e353b1d0c09a425495ca2a60fd53a62e

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Glutathionylation of pyruvate dehydrogenase complex E2 and inflammatory cytokine production during acute inflammation are magnified by mitochondrial oxidative stress

Authors: David L. Long, Charles E. McCall, Leslie B. Poole

Source: Redox Biology, Vol 65, Iss , Pp 102841- (2023)

Subject Terms: Inflammation, Glutathionylation, Lipoamide, Pyruvate dehydrogenase complex, Sepsis, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231723002422; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/3f8315755fd84d899189a7b058cb3110

Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

Authors: Allison K. Meyers, Zhan Wang, Wenzheng Han, Qingxia Zhao, Manal Zabalawi, Likun Duan, Juan Liu, Qianyi Zhang, Rajesh K. Manne, Felipe Lorenzo, Matthew A. Quinn, Qianqian Song, Daping Fan, Hui-Kuan Lin, Cristina M. Furdui, Jason W. Locasale, Charles E. McCall, Xuewei Zhu

Source: Cell Reports, Vol 42, Iss 1, Pp 111941- (2023)

Subject Terms: CP: Immunology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124722018423; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/9e44575ee34a4202a7a3e462e4561170

KDM6A Lysine Demethylase Directs Epigenetic Polarity of MDSCs during Murine Sepsis

Authors: Isatou Bah, Tuqa Alkhateeb, Dima Youssef, Zhi Q. Yao, Charles E. McCall, Mohamed El Gazzar

Source: Journal of Innate Immunity, Pp 1-12 (2021)

Subject Terms: sepsis, myeloid-derived suppressor cell, immune suppression, hotairm1, epigenetics, Medicine, Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/517407; https://doaj.org/toc/1662-811X; https://doaj.org/toc/1662-8128

Access URL: https://doaj.org/article/e05f50ddef4a4addaaec5261642bf9f1

Dichloroacetate improves systemic energy balance and feeding behavior during sepsis

Authors: Tae Seok Oh, Manal Zabalawi, Shalini Jain, David Long, Peter W. Stacpoole, Charles E. McCall, Matthew A. Quinn

Source: JCI Insight, Vol 7, Iss 12 (2022)

Subject Terms: Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/5d981fcaf4444ba598df155e5fb19c2a

Editorial: The Roles of Mitochondria in Immunity

Authors: Naeem K. Patil, Julia K. Bohannon, Vidula Vachharajani, Charles E. McCall

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: mitochondria, immunity, TCA cycle, itaconate, oxidative stress, inflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.914639/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/93b47db0ab19473eb07a8d3237ca4c07

Inhibiting KDM6A Demethylase Represses Long Non-Coding RNA Hotairm1 Transcription in MDSC During Sepsis

Authors: Isatou Bah, Dima Youssef, Zhi Q. Yao, Charles E. McCall, Mohamed El Gazzar

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: sepsis, KDM6A, Hotairm1, MDSC, immune suppression, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.823660/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a392f19a3324495d81ecb915b3b4ed51

Hematopoietic Cell-Specific SLC37A2 Deficiency Accelerates Atherosclerosis in LDL Receptor-Deficient Mice

Authors: Qingxia Zhao, Zhan Wang, Allison K. Meyers, Jennifer Madenspacher, Manal Zabalawi, Qianyi Zhang, Elena Boudyguina, Fang-Chi Hsu, Charles E. McCall, Cristina M. Furdui, John S. Parks, Michael B. Fessler, Xuewei Zhu

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: glucose 6-phosphate transporter, macrophage inflammation, IL-10, efferocytosis, atherosclerosis, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.777098/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/faf5fd19e0c94aa199d2c274dfbde07e

Solute Carrier Family 37 Member 2 (SLC37A2) Negatively Regulates Murine Macrophage Inflammation by Controlling Glycolysis

Authors: Zhan Wang, Qingxia Zhao, Yan Nie, Yi Yu, Biswapriya B. Misra, Manal Zabalawi, Jeff W. Chou, Chia-Chi C. Key, Anthony J. Molina, Matthew A. Quinn, Michael B. Fessler, John S. Parks, Charles E. McCall, Xuewei Zhu

Source: iScience, Vol 23, Iss 5, Pp - (2020)

Subject Terms: Cell Biology, Functional Aspects of Cell Biology, Immunology, Metabolism, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004220303102; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/5cfa8e8902044865933594eb473988ea

Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Authors: Yongmei Liu, Lindsay M. Reynolds, Jingzhong Ding, Li Hou, Kurt Lohman, Tracey Young, Wei Cui, Zhiqing Huang, Carole Grenier, Ma Wan, Hendrik G. Stunnenberg, David Siscovick, Lifang Hou, Bruce M. Psaty, Stephen S. Rich, Jerome I. Rotter, Joel D. Kaufman, Gregory L. Burke, Susan Murphy, David R. Jacobs, Wendy Post, Ina Hoeschele, Douglas A. Bell, David Herrington, John S. Parks, Russell P. Tracy, Charles E. McCall, James H. Stein

Source: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ac550ee42c704e9ea9413177742ac970