The potential anti-arrhythmic effect of SGLT2 inhibitors

Authors: Hong-Yi Duan, Hector Barajas-Martinez, Charles Antzelevitch, Dan Hu

Source: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)

Subject Terms: SGLT2 inhibitor, Arrhythmias, Intracellular sodium, Myocardial metabolism, Autophagy, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/6e17f767eae44338b0347bb08197d2ba

Electrocardiographic variables associated with underlying Brugada syndrome or drug‐induced Type 1 Brugada pattern in patients with slow/fast atrioventricular nodal reentrant tachycardia

Authors: Can Hasdemir, Hatice Sahin, Gulten Duran, Mehmet N. Orman, Umut Kocabas, Serdar Payzin, Mehmet Aydin, Charles Antzelevitch

Source: Journal of Arrhythmia, Vol 38, Iss 4, Pp 633-641 (2022)

Subject Terms: atrioventricular nodal reentrant tachycardia, ECG, electrocardiography, J wave syndromes, supraventricular tachycardia, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1880-4276; https://doaj.org/toc/1883-2148

Access URL: https://doaj.org/article/2cc0d4af2d00453fbdd4c60b1511d4cb

Clinical characteristics and electrophysiologic properties of SCN5A variants in fever-induced Brugada syndromeResearch in context

Authors: Gan-Xiao Chen, Hector Barajas-Martínez, Giuseppe Ciconte, Cheng-I Wu, Michelle M. Monasky, Hao Xia, Bian Li, John A. Capra, Kai Guo, Zhong-He Zhang, Xiu Chen, Bo Yang, Hong Jiang, Gary Tse, Chloe Miu Mak, Yoshiyasu Aizawa, Michael H. Gollob, Charles Antzelevitch, Arthur A.M. Wilde, Carlo Pappone, Dan Hu

Source: EBioMedicine, Vol 87, Iss , Pp 104388- (2023)

Subject Terms: Brugada syndrome, Fever, Genetics, Sudden cardiac death, Ventricular arrhythmias, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396422005709; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/d15cdf54f8b04193a86c33c050c93e71

Mechanisms underlying the antiarrhythmic effect of ARumenamide-787 in experimental models of the J wave syndromes and hypothermia.

Authors: José M Di Diego, Hector Barajas-Martinez, Robert Cox, Victoria M Robinson, Joseph Jung, Mohamed Fouda, Bence Patocskai, Mena Abdelsayed, Peter C Ruben, Charles Antzelevitch

Source: PLoS ONE, Vol 18, Iss 5, p e0281977 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0281977&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d3a06d40c7504261885014a5c3d40279

Clinical and Functional Genetic Characterization of the Role of Cardiac Calcium Channel Variants in the Early Repolarization Syndrome

Authors: Xiu Chen, Hector Barajas-Martínez, Hao Xia, Zhonghe Zhang, Ganxiao Chen, Bo Yang, Hong Jiang, Charles Antzelevitch, Dan Hu

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: early repolarization syndrome, calcium channel, gene mutation, trafficking, sudden cardiac death, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.680819/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/ddd94a1ba081449cb6e74c74fa1289e9

GSTM3 variant is a novel genetic modifier in Brugada syndrome, a disease with risk of sudden cardiac death

Authors: Jyh-Ming Jimmy Juang, Anna Binda, Shyh-Jye Lee, Juey-Jen Hwang, Wen-Jone Chen, Yen-Bin Liu, Lian-Yu Lin, Chih-Chieh Yu, Li-Ting Ho, Hui-Chun Huang, Ching-Yu Julius Chen, Tzu-Pin Lu, Liang-Chuan Lai, Shih-Fan Sherri Yeh, Ling-Ping Lai, Eric Y. Chuang, Ilaria Rivolta, Charles Antzelevitch

Source: EBioMedicine, Vol 57, Iss , Pp 102843- (2020)

Subject Terms: Inherited cardiac arrhythmia, Genetics, Sudden cardiac death, Brugada syndrome, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396420302188; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/2503e6de2e7f48c3bb2286a2fabb8003

Identification, clinical manifestation and structural mechanisms of mutations in AMPK associated cardiac glycogen storage disease

Authors: Dan Hu, Dong Hu, Liwen Liu, Daniel Barr, Yang Liu, Norma Balderrabano-Saucedo, Bo Wang, Feng Zhu, Yumei Xue, Shulin Wu, BaoLiang Song, Heather McManus, Katherine Murphy, Katherine Loes, Arnon Adler, Lorenzo Monserrat, Charles Antzelevitch, Michael H. Gollob, Perry M. Elliott, Hector Barajas-Martinez

Source: EBioMedicine, Vol 54, Iss , Pp - (2020)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396420300980; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/261fdad085bf4de79b25dd66139363da

Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes.

Authors: José M Di Diego, Bence Patocskai, Hector Barajas-Martinez, Virág Borbáth, Michael J Ackerman, Alexander Burashnikov, Jérôme Clatot, Gui-Rong Li, Victoria M Robinson, Dan Hu, Charles Antzelevitch

Source: PLoS ONE, Vol 15, Iss 11, p e0242747 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3cb25873eea6466eadaeb09bad7cd916

Susceptibility to Ventricular Arrhythmias Resulting from Mutations in FKBP1B, PXDNL, and SCN9A Evaluated in hiPSC Cardiomyocytes

Authors: Hector Barajas-Martinez, Maya Smith, Dan Hu, Robert J. Goodrow, Colleen Puleo, Can Hasdemir, Charles Antzelevitch, Ryan Pfeiffer, Jacqueline A. Treat, Jonathan M. Cordeiro

Source: Stem Cells International, Vol 2020 (2020)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://doaj.org/toc/1687-966X; https://doaj.org/toc/1687-9678

Access URL: https://doaj.org/article/680c9642bcdf4b898046c0ee9402fb20

Mutations in NaV1.5 Reveal Calcium-Calmodulin Regulation of Sodium Channel

Authors: Eyal Nof, Leonid Vysochek, Eshcar Meisel, Elena Burashnikov, Charles Antzelevitch, Jerome Clatot, Roy Beinart, David Luria, Michael Glikson, Shimrit Oz

Source: Frontiers in Physiology, Vol 10 (2019)

Subject Terms: β1-subunit, calmodulin, cardiac arrhythmia, channelopathies, DIII-IV linker, heart, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2019.00700/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/455b4dcdefbb419d9a75b96839332b44

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

Authors: Charles Antzelevitch, PhD, FHRS, Gan-Xin Yan, MD, PhD, Michael J. Ackerman, MD, PhD, Martin Borggrefe, MD, Domenico Corrado, MD, PhD, Jihong Guo, MD, Ihor Gussak, MD, PhD, Can Hasdemir, MD, Minoru Horie, MD, Heikki Huikuri, MD, Changsheng Ma, MD, Hiroshi Morita, MD, PhD, Gi-Byoung Nam, MD, PhD, Frederic Sacher, MD, PhD, Wataru Shimizu, MD, PhD, Sami Viskin, MD, Arthur A.M. Wilde, MD, PhD, FHRS

Source: Journal of Arrhythmia, Vol 32, Iss 5, Pp 315-339 (2016)

Subject Terms: Sudden cardiac death, J wave, Brugada syndrome, Early repolarization syndrome, Cardiac arrhythmia, Ventricular fibrillation, Inherited cardiac arrhythmia syndrome, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1880427616300734; https://doaj.org/toc/1880-4276

Access URL: https://doaj.org/article/250694f154614c60a6d5091b06710988

Pooled Analysis of Risk Stratification of Spontaneous Type 1 Brugada ECG: Focus on the Influence of Gender and EPS

Authors: Xinye Li, Frédéric Sacher, Kengo F. Kusano, Hector Barajas-Martinez, Nian Liu, Yanda Li, Yonghong Gao, Tong Liu, Hongcai Shang, Charles Antzelevitch, Dan Hu, Yanwei Xing

Source: Frontiers in Physiology, Vol 9 (2019)

Subject Terms: Brugada syndrome, risk stratification, gender, syncope, electrophysiology, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2018.01951/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/73660a4da83b42558a433415daf3f1af

Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis.

Authors: Mariana A Argenziano, Michael Xavier Doss, Megan Tabler, Agapios Sachinidis, Charles Antzelevitch

Source: PLoS ONE, Vol 14, Iss 5, p e0216928 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d6b19268b4e2413aab003576d8845748

Impact of Ancestral Differences and Reassessment of the Classification of Previously Reported Pathogenic Variants in Patients With Brugada Syndrome in the Genomic Era: A SADS-TW BrS Registry

Authors: Ching-Yu Julius Chen, Tzu-Pin Lu, Lian-Yu Lin, Yen-Bin Liu, Li-Ting Ho, Hui-Chun Huang, Ling-Ping Lai, Juey-Jen Hwang, Shih-Fan Sherri Yeh, Cho-Kai Wu, Jyh-Ming Jimmy Juang, Charles Antzelevitch

Source: Frontiers in Genetics, Vol 9 (2019)

Subject Terms: Brugada syndrome, sudden cardiac death, inherited cardiac arrhythmia syndrome, allele frequency, pathogenic variants, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2018.00680/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/759f609602ee4cedbd29dd7c23824283

Drug-induced Brugada syndrome

Authors: Yoshino Minoura, Youichi Kobayashi, Charles Antzelevitch

Source: Journal of Arrhythmia, Vol 29, Iss 2, Pp 88-95 (2013)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1880427613000434; https://doaj.org/toc/1880-4276

Access URL: https://doaj.org/article/47a6632388254d41ac5db3388ecbc4c1

Further Insights in the Most Common SCN5A Mutation Causing Overlapping Phenotype of Long QT Syndrome, Brugada Syndrome, and Conduction Defect

Authors: Christian Veltmann, Hector Barajas‐Martinez, Christian Wolpert, Martin Borggrefe, Rainer Schimpf, Ryan Pfeiffer, Gabriel Cáceres, Elena Burashnikov, Charles Antzelevitch, Dan Hu

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)

Subject Terms: Brugada syndrome, channelopathies, conduction defect, electrophysiology, genetics, long QT syndrome, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/f6114996b262439ea76db54cbec76411

Congenital Short QT Syndrome

Authors: Charles Antzelevitch, Johnson Francis

Source: Indian Pacing and Electrophysiology Journal, Vol 4, Iss 2, Pp 46-49 (2004)

Subject Terms: short QT syndrome, genetic studies, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.ipej.org/0402/antzelevitch.htm; https://doaj.org/toc/0972-6292

Access URL: https://doaj.org/article/1785315a6b1948d69df29a37113bfee2

A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis.

Authors: Jessica A Hennessey, Nicole J Boczek, Yong-Hui Jiang, Joelle D Miller, William Patrick, Ryan Pfeiffer, Brittan S Sutphin, David J Tester, Hector Barajas-Martinez, Michael J Ackerman, Charles Antzelevitch, Ronald Kanter, Geoffrey S Pitt

Source: PLoS ONE, Vol 9, Iss 9, p e106982 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4153713?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/61084eec7b314ac9a3f3362a62a9ce33

J wave syndromes as a cause of sudden arrhythmic death

Authors: Charles Antzelevitch

Source: Cardiogenetics, Vol 3, Iss 1, Pp e2-e2 (2013)

Subject Terms: cardiac arrhythmias, sudden cardiac death, early repolarization syndrome, brugada syndrome, idiopathic ventricular fibrillation., Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.pagepressjournals.org/index.php/cardiogen/article/view/288; https://doaj.org/toc/2035-8253; https://doaj.org/toc/2035-8148

Access URL: https://doaj.org/article/7b814a639459464b81cabb7562a1b1e0

Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure.

Authors: Yang Liu, Rong Bai, Lin Wang, Cuntai Zhang, Ruifu Zhao, Deli Wan, Xinshan Chen, Gabriel Caceres, Daniel Barr, Hector Barajas-Martinez, Charles Antzelevitch, Dan Hu

Source: PLoS ONE, Vol 8, Iss 5, p e64603 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3669303?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cf5b0752f52c4fef819bdba4a452870e