Identification of immune suppressor candidates utilizing comparative transcriptional profiling in histiocytic sarcoma

Authors: Jennifer A. Lenz, Brandon Peng, Charles‑Antoine Assenmacher, Austin King, Paul J. Zhang, Robert G. Maki, M. Andres Blanco, Enrico Radaelli, Matthew J. Atherton

Source: Cancer Immunology, Immunotherapy, Vol 74, Iss 2, Pp 1-8 (2025)

Subject Terms: Histiocytic sarcoma, Osteopontin, PD-1, TXNIP, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1432-0851

Access URL: https://doaj.org/article/10d3f842663c49eca2dfbf85f0516a6a

Prognostic and therapeutic implications of tumor-restrictive type III collagen in the breast cancer microenvironment

Authors: Daniel C. Stewart, Becky K. Brisson, Bassil Dekky, Ashton C. Berger, William Yen, Elizabeth A. Mauldin, Claudia Loebel, Deborah Gillette, Charles-Antoine Assenmacher, Corisa Quincey, Darko Stefanovski, Massimo Cristofanilli, Edna Cukierman, Jason A. Burdick, Virginia F. Borges, Susan W. Volk

Source: npj Breast Cancer, Vol 10, Iss 1, Pp 1-19 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2374-4677

Access URL: https://doaj.org/article/1f8570802070429fb59316d40cdbc510

Urothelial carcinoma associated with a long‐term indwelling cystostomy component of a subcutaneous ureteral bypass device in a domestic shorthair cat

Authors: Samantha Lackeyram‐Owen, Erin Gibson, Jennifer Reetz, Taylor Chan, Charles‐Antoine Assenmacher, Dana L. Clarke

Source: Journal of Veterinary Internal Medicine, Vol 38, Iss 5, Pp 2664-2668 (2024)

Subject Terms: feline, interventional radiology, oncology, radiology and diagnostic imaging, renal/urinary tract, ureteral obstruction, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/0891-6640; https://doaj.org/toc/1939-1676

Access URL: https://doaj.org/article/3f39fca8235c4088963b439e08c9d48f

The STING agonist IMSA101 enhances chimeric antigen receptor T cell function by inducing IL-18 secretion

Authors: Ugur Uslu, Lijun Sun, Sofia Castelli, Amanda V. Finck, Charles-Antoine Assenmacher, Regina M. Young, Zhijian J. Chen, Carl H. June

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0776d7dc8ea14173bb63673e70265732

Correction: Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis

Authors: Enrico Radaelli, Charles-Antoine Assenmacher, Jillian Verrelle, Esha Banerjee, Florence Manero, Salim Khiati, Anais Girona, Guillermo Lopez-Lluch, Placido Navas, Marco Spinazzi

Source: eLife, Vol 13 (2024)

Subject Terms: Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/103278; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/6f0393dc2860402fb63fbef2355f349c

Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors

Authors: Zebin Xiao, Leslie Todd, Li Huang, Estela Noguera-Ortega, Zhen Lu, Lili Huang, Meghan Kopp, Yue Li, Nimisha Pattada, Wenqun Zhong, Wei Guo, John Scholler, Maria Liousia, Charles-Antoine Assenmacher, Carl H. June, Steven M. Albelda, Ellen Puré

Source: Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8293ae22274440439fe76629503609b5

Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy

Authors: Jinping Liu, Lan Cheng, Hilana El‐Mekkoussi, Charles‐Antoine Assenmacher, Michelle Y. Y. Lee, Danielle R. Jaffe, Kaisha Garvin‐Darby, Ashleigh Morgan, Elisabetta Manduchi, Jonathan Schug, Klaus H. Kaestner

Source: Cancer Communications, Vol 43, Iss 6, Pp 706-710 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/5963c665bcf24e208a07aef245825a7a

316 STING agonist-induced IL-18 secretion enhances CAR T cell function

Authors: Lijun Sun, Carl H June, Zhijian Chen, Amanda Finck, Ugur Uslu, Sofia Castelli, Regina M Young, Charles-Antoine Assenmacher

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/9466a2088afc4d539dc332d16640c40a

5 Severely immunodeficient NOG-EXL mice allow for humanization and development of a human glioblastoma-derived tumor microenvironment

Authors: Cecile Alanio, Zev Binder, Donald O’Rourke, Charles-Antoine Assenmacher, Lamia Lamrani, Anthony Secreto, Nicholas Skuli, Moriah Jacobson, Elinor Willis, Enrico Radaelli, Maclean Nasrallah

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/836250dbabdd4a12b67364ab8e823910

22 Humanized NOG-EXL mice exhibit improved overall survival and less severe myeloid cell activation relative to humanized NSG-SGM3 mice

Authors: Zev Binder, Charles-Antoine Assenmacher, Elinor Willis, Enrico Radaelli, Jillian Verrelle, Esha Banerjee, James C Tarrant, Nicolas Skuli, Moriah L Jacobson

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/6d8b03048d2f4291923672da843e7972

261 Synergistic antitumor effects of mouse mesothelin-directed CAR (mmeso-CAR) T cells and αCD40 in a syngeneic model of PDAC

Authors: Carl H June, John Scholler, Joseph A Fraietta, Andrew Rech, Daniel Martinez, David Mai, Omar Johnson, Khatuna Gabunia, Regina M Young, Charles-Antoine Assenmacher, Enrico Radaelli, Giulia Golinelli, Ting-Jia Fan, Jordan Reff, Zachary Ferraro, Decheng Song, Aasha Gupta, Mansi Deshmukh, He N Xu, Wesley V Wilson, Julia C Tchou, Bruce L Levine

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/83b0afd714cd497b9913acbaca399ca6

238 Potentiating CAR T cell therapy through synthetic IL-9R signaling

Authors: Carl H June, Mikko Siurala, Charles-Antoine Assenmacher

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/d8e40836badb46e0be3368c204eea403

Anti-inflammatory effects of hunger are transmitted to the periphery via projection-specific AgRP circuits

Authors: Michelle L. Klima, Kayla A. Kruger, Nitsan Goldstein, Santiago Pulido, Aloysius Y.T. Low, Charles-Antoine Assenmacher, Amber L. Alhadeff, J. Nicholas Betley

Source: Cell Reports, Vol 42, Iss 11, Pp 113338- (2023)

Subject Terms: CP: Neuroscience, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723013505; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/706905b9a93e48a9811f41ed68326f6b

Automated Nuclear Morphometry: A Deep Learning Approach for Prognostication in Canine Pulmonary Carcinoma to Enhance Reproducibility

Authors: Imaine Glahn, Andreas Haghofer, Taryn A. Donovan, Brigitte Degasperi, Alexander Bartel, Theresa Kreilmeier-Berger, Philip S. Hyndman, Hannah Janout, Charles-Antoine Assenmacher, Florian Bartenschlager, Pompei Bolfa, Michael J. Dark, Andrea Klang, Robert Klopfleisch, Sophie Merz, Barbara Richter, F. Yvonne Schulman, Jonathan Ganz, Josef Scharinger, Marc Aubreville, Stephan M. Winkler, Christof A. Bertram

Source: Veterinary Sciences, Vol 11, Iss 6, p 278 (2024)

Subject Terms: anisokaryosis, artificial intelligence, dog, image processing, mitotic count, nuclear pleomorphism, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.mdpi.com/2306-7381/11/6/278; https://doaj.org/toc/2306-7381

Access URL: https://doaj.org/article/d3b917419c5f4b049009eb5d807f0748

The IAP antagonist birinapant enhances chimeric antigen receptor T cell therapy for glioblastoma by overcoming antigen heterogeneity

Authors: Edward Z. Song, Xin Wang, Benjamin I. Philipson, Qian Zhang, Radhika Thokala, Logan Zhang, Charles-Antoine Assenmacher, Zev A. Binder, Guo-li Ming, Donald M. O’Rourke, Hongjun Song, Michael C. Milone

Source: Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 288-304 (2022)

Subject Terms: IAP antagonist, birinapant, CAR T cell, glioblastoma, antigen heterogeneity, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770522001395; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/52ea338bdced4e4cb747e87c08377ff4

Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis

Authors: Enrico Radaelli, Charles-Antoine Assenmacher, Jillian Verrelle, Esha Banerjee, Florence Manero, Salim Khiati, Anais Girona, Guillermo Lopez-Lluch, Placido Navas, Marco Spinazzi

Source: eLife, Vol 12 (2023)

Subject Terms: PARL, ferroptosis, GPX4, coenzyme Q, spermatogenesis, mitochondria, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/84710; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/a88355b7b3524c5db145e8b32e4e08b3

Can Sequential Images from the Same Object Be Used for Training Machine Learning Models? A Case Study for Detecting Liver Disease by Ultrasound Radiomics

Authors: Laith R. Sultan, Theodore W. Cary, Maryam Al-Hasani, Mrigendra B. Karmacharya, Santosh S. Venkatesh, Charles-Antoine Assenmacher, Enrico Radaelli, Chandra M. Sehgal

Source: AI, Vol 3, Iss 3, Pp 739-750 (2022)

Subject Terms: medical imaging, quantitative ultrasound, machine learning, independent data, liver disease, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: https://www.mdpi.com/2673-2688/3/3/43; https://doaj.org/toc/2673-2688

Access URL: https://doaj.org/article/91af7bdbbbdc497586c2bb233122321d

Plasma and tissue angiotensin‐converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease

Authors: Éva Larouche‐Lebel, Kerry A. Loughran, Mark A. Oyama, Phil F. Solter, Danielle S. Laughlin, Melissa D. Sánchez, Charles‐Antoine Assenmacher, Philip R. Fox, Ryan C. Fries

Source: Journal of Veterinary Internal Medicine, Vol 33, Iss 4, Pp 1571-1584 (2019)

Subject Terms: angiotensin 1‐7, angiotensin II, degenerative mitral valve disease, renin‐angiotensin‐aldosterone system, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/0891-6640; https://doaj.org/toc/1939-1676

Access URL: https://doaj.org/article/02b3d8c4ae68407f976d0e8cf1b5ad1f

Post Mortem Study on the Effects of Routine Handling and Manipulation of Laboratory Mice

Authors: Charles-Antoine Assenmacher, Matthew Lanza, James C Tarrant, Kristin L Gardiner, Eric Blankemeyer, Enrico Radaelli

Source: Animals, Vol 12, Iss 23, p 3234 (2022)

Subject Terms: laboratory mouse, handling, restraint, manipulation, osteoarticular trauma, histopathology, Veterinary medicine, SF600-1100, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2615/12/23/3234; https://doaj.org/toc/2076-2615

Access URL: https://doaj.org/article/8ab36dd0b58e4a18998ec7572777d7e0