An Overview of Current Methods for Real-world Applications to Generalize or Transport Clinical Trial Findings to Target Populations of Interest

Authors: Ling, Albee Y., Montez-Rath, Maria E., Carita, Paulo, Chandross, Karen J., Lucats, Laurence, Meng, Zhaoling, Sebastien, Bernard, Kapphahn, Kris, Desai, Manisha

Source: Epidemiology. 34(5):627-636

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195932817.0x000001&indx=1&recIds=ETOCvdc_100195932817.0x000001

Characterizing real world safety profile of oral Janus kinase inhibitors among adult atopic dermatitis patients: evidence transporting from the rheumatoid arthritis population

Authors: Montez-Rath, Maria E., Lubwama, Robert, Kapphahn, Kris, Ling, Albee Y., LoCasale, Robert, Robinson, Lacey, Chandross, Karen J., Desai, Manisha

Source: Current medical research and opinion. 38(8):1431-1437

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157053981.0x000001&indx=1&recIds=ETOCvdc_100157053981.0x000001

Calibration and Uncertainty in Neural Time-to-Event Modeling

Authors: Chapfuwa, Paidamoyo, Tao, Chenyang, Li, Chunyuan, Khan, Irfan, Chandross, Karen J., Pencina, Michael J., Carin, Lawrence, Henao, Ricardo

Source: IEEE transactions on neural networks and learning systems. 34(4):1666-1680

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Technology-Enabled Clinical Trials

Authors: Marquis-Gravel, Guillaume, Roe, Matthew T., Turakhia, Mintu P., Boden, William, Temple, Robert, Sharma, Abhinav, Hirshberg, Boaz, Slater, Paul, Craft, Noah, Stockbridge, Norman, McDowell, Bryan, Waldstreicher, Joanne, Bourla, Ariel, Bansilal, Sameer, Wong, Jennifer L., Meunier, Claire, Kassahun, Helina, Coran, Philip, Bataille, Lauren, Patrick-Lake, Bray, Hirsch, Brad, Reites, John, Mehta, Rajesh, Muse, Evan D., Chandross, Karen J., Silverstein, Jonathan C., Silcox, Christina, Overhage, J. Marc, Califf, Robert M., Peterson, Eric D.

Source: Circulation. 140(17):1426-1436

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Turning Blood into Brain: Cells Bearing Neuronal Antigens Generated in Vivo from Bone Marrow

Authors: Mezey, Éva, Chandross, Karen J., Harta, Gyöngyi, Maki, Richard A., McKercher, Scott R.

Source: Science, 2000 Dec 01. 290(5497), 1779-1782.

Access URL: https://www.jstor.org/stable/3081774

Using Digital Health Technology to Better Generate Evidence and Deliver Evidence-Based Care

Authors: Sharma, Abhinav, Harrington, Robert A., McClellan, Mark B., Turakhia, Mintu P., Eapen, Zubin J., Steinhubl, Steven, Mault, James R., Majmudar, Maulik D., Roessig, Lothar, Chandross, Karen J., Green, Eric M., Patel, Bakul, Hamer, Andrew, Olgin, Jeffrey, Rumsfeld, John S., Roe, Matthew T., Peterson, Eric D.

Source: Journal of the American College of Cardiology. 71(23):2680-2690

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Disease progression strikingly differs in research and real-world Parkinson's populations.

Authors: Beaulieu-Jones, Brett K., Frau, Francesca, Bozzi, Sylvie, Chandross, Karen J., Peterschmitt, M. Judith, Cohen, Caroline, Coulovrat, Catherine, Kumar, Dinesh, Kruger, Mark J., Lipnick, Scott L., Fitzsimmons, Lane, Kohane, Isaac S., Scherzer, Clemens R.

Source: NPJ Parkinson's Disease; 3/13/2024, Vol. 10 Issue 1, p1-11, 11p

High-Content Phenotypic Screening and Triaging Strategy to Identify Small Molecules Driving Oligodendrocyte Progenitor Cell Differentiation

Authors: Peppard, Jane V., Rugg, Catherine A., Smicker, Matthew A., Powers, Elaine, Harnish, Erica, Prisco, Joy, Cirovic, Dragan, Wright, Paul S., August, Paul R., Chandross, Karen J. ^*

Source: In SLAS Discovery March 2015 20(3):382-390

Transporting observational study results to a target population of interest using inverse odds of participation weighting.

Authors: Ling, Albee Y., Jreich, Rana, Montez-Rath, Maria E., Meng, Zhaoling, Kapphahn, Kris, Chandross, Karen J., Desai, Manisha

Source: PLoS ONE; 12/15/2022, Vol. 17 Issue 12, p1-13, 13p

Subject Terms: SCIENTIFIC observation, METASTATIC breast cancer, ELECTRONIC health records, ESTROGEN receptors, FULVESTRANT

Calibration and Uncertainty in Neural Time-to-Event Modeling

Authors: Chapfuwa, Paidamoyo, Tao, Chenyang, Li, Chunyuan, Khan, Irfan, Chandross, Karen J., Pencina, Michael J., Carin, Lawrence, Henao, Ricardo

Source: IEEE Transactions on Neural Networks and Learning Systems; 2023, Vol. 34 Issue: 4 p1666-1680, 15p

Plasticity of adult bone marrow stem cells

Authors: Chandross, Karen J., Mezey, Éva

Source: In Advances in Cell Aging and Gerontology 2002 9:73-95

Accelerating diagnosis of Parkinson's disease through risk prediction.

Authors: Yuan, William, Beaulieu-Jones, Brett, Krolewski, Richard, Palmer, Nathan, Veyrat-Follet, Christine, Frau, Francesca, Cohen, Caroline, Bozzi, Sylvie, Cogswell, Meaghan, Kumar, Dinesh, Coulouvrat, Catherine, Leroy, Bruno, Fischer, Tanya Z., Sardi, S. Pablo, Chandross, Karen J., Rubin, Lee L., Wills, Anne-Marie, Kohane, Isaac, Lipnick, Scott L.

Source: BMC Neurology; 5/18/2021, Vol. 21 Issue 1, p1-12, 12p

Subject Terms: PARKINSON'S disease, DIAGNOSIS, TREMOR, PATHOLOGY, MEDICAL personnel, GAIT disorders, MOVEMENT disorders

Bone marrow: a possible alternative source of cells in the adult nervous system

Authors: Mezey, Éva ^*, Chandross, Karen J

Source: In European Journal of Pharmacology 2000 405(1):297-302

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17beta-estradiol protects oligodendrocytes from cytotoxicity induced cell death.

Authors: Takao, Toshihiro, Flint, Nicole, Lan Lee, Nicole, Xiaoyou Ying, Merrill, Jean, Chandross, Karen J.

Source: Journal of Neurochemistry; 5/1/2004, Vol. 89 Issue 3, p660-673, 14p

Subject Terms: CENTRAL nervous system, ESTROGEN receptors, IMMUNOHISTOCHEMISTRY, HORMONES, CELL death, MULTIPLE sclerosis, PREGNANT women

Tracking oligodendrocytes during development and regeneration.

Authors: Chandross, Karen J., Champagne, Benedicte, Auble, Kathryn, Hudson, Lynn D.

Source: Microscopy Research & Technique; Mar2001, Vol. 52 Issue 6, p766-777, 12p

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Nerve injury and inflammatory cytokines modulate gap junctions in the peripheral nervous system.

Authors: Chandross, Karen J.

Source: Glia; Sep1998, Vol. 24 Issue 1, p21-31, 11p

Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation

Authors: Sim, Fraser J., Lang, Jennifer K., Waldau, Ben, Roy, Neeta S., Schwartz, Theodore E., Pilcher, Webster H., Chandross, Karen J., Natesan, Sridaran, Merrill, Jean E., Goldmanm, Steven A.

Source: Annals of Neurology; May 2006, Vol. 59 Issue: 5 p763-779, 17p