Ehf controls mammary alveolar lineage differentiation and is a putative suppressor of breast tumorigenesis

Authors: Nightingale, Rebecca, Reehorst, Camilla M., Vukelic, Natalia, Papadopoulos, Nikolaos, Liao, Yang, Guleria, Shalini, Bell, Caroline, Vaillant, François, Paul, Sudip, Luk, Ian Y., Dhillon, Amardeep S., Jenkins, Laura J., Morrow, Riley J., Jackling, Felicity C., Chand, Ashwini L., Chisanga, David, Chen, Yunshun, Williams, David S., Anderson, Robin L., Ellis, Sarah, Meikle, Peter J., Shi, Wei, Visvader, Jane E., Pal, Bhupinder, Mariadason, John M.

Source: In Developmental Cell 5 August 2024 59(15):1988-2004

Repurposing of drugs as STAT3 inhibitors for cancer therapy

Authors: Thilakasiri, Pathum S., Dmello, Rhynelle S., Nero, Tracy L., Parker, Michael W., Ernst, Matthias, Chand, Ashwini L. ^*

Source: In Seminars in Cancer Biology January 2021 68:31-46

DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression.

Authors: Afshar-Sterle, Shoukat, Carli, Annalisa L.E., O'Keefe, Ryan, Tse, Janson, Fischer, Stefanie, Azimpour, Alexander I., Baloyan, David, Elias, Lena, Thilakasiri, Pathum, Patel, Onisha, Ferguson, Fleur M., Eissmann, Moritz F., Chand, Ashwini L., Gray, Nathanael S., Busuttil, Rita, Boussioutas, Alex, Lucet, Isabelle S., Ernst, Matthias, Buchert, Michael

Source: Science Signaling; 9/17/2024, Vol. 17 Issue 854, p1-18, 18p

Subject Terms: STROMAL cell-derived factor 1, CANCER stem cells, STOMACH cancer, EPITHELIAL-mesenchymal transition, TUMOR growth

Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer.

Authors: Dmello, Rhynelle S., Palmieri, Michelle, Thilakasiri, Pathum S., Doughty, Larissa, Nero, Tracy L., Poh, Ashleigh R., To, Sarah Q., Lee, Erinna F., Douglas Fairlie, W., Mielke, Lisa, Parker, Michael W., Poon, Ivan K. H., Batlle, Eduard, Ernst, Matthias, Chand, Ashwini L.

Source: Cell Death & Disease; Apr2024, Vol. 15 Issue 4, p1-13, 13p

Liver receptor homologue-1 expression in ovarian epithelial and granulosa cell tumours

Authors: Chand, Ashwini L., Pathirage, Niroshani, Lazarus, Kyren, Chu, Simon, Drummond, Ann E., Fuller, Peter J., Clyne, Colin D.

Source: In Steroids July 2013 78(7):700-706

Evaluating the benefits of renin-angiotensin system inhibitors as cancer treatments

Authors: Perini, Marcos V., Dmello, Rhynelle S., Nero, Tracy L., Chand, Ashwini L.

Source: Pharmacology and therapeutics. 211

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115187974.0x000001&indx=1&recIds=ETOCvdc_100115187974.0x000001

Therapeutic potential of Liver Receptor Homolog-1 modulators

Authors: Lazarus, Kyren A., Wijayakumara, Dhilushi, Chand, Ashwini L., Simpson, Evan R., Clyne, Colin D.

Source: In Journal of Steroid Biochemistry and Molecular Biology July 2012 130(3-5):138-146

Tissue-specific regulation of aromatase promoter II by the orphan nuclear receptor LRH-1 in breast adipose stromal fibroblasts

Authors: Chand, Ashwini L., Herridge, Kerrie A., Howard, Tamara L., Simpson, Evan R., Clyne, Colin D.

Source: In Steroids 2011 76(8):741-744

Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth

Authors: Thilakasiri, Pathum, Huynh, Jennifer, Poh, Ashleigh R, Tan, Chin Wee, Nero, Tracy L, Tran, Kelly, Parslow, Adam C, Afshar‐Sterle, Shoukat, Baloyan, David, Hannan, Natalie J, Buchert, Michael, Scott, Andrew Mark, Griffin, Michael DW, Hollande, Frederic, Parker, Michael W, Putoczki, Tracy L, Ernst, Matthias, Chand, Ashwini L

Source: EMBO molecular medicine. 11(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090552368.0x000001&indx=1&recIds=ETOCvdc_100090552368.0x000001

Aromatase expression is increased in BRCA1 mutation carriers

Authors: Chand Ashwini L, Simpson Evan R, Clyne Colin D

Source: BMC Cancer, Vol 9, Iss 1, p 148 (2009)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2407/9/148; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/d57d2c578a2b44a9a78b525a2b3d94b4

Laser capture microdissection and cDNA array analysis of endometrium identify CCL16 and CCL21 as epithelial-derived inflammatory mediators associated with endometriosis

Authors: Jones Rebecca L, Murray Andrew S, Chand Ashwini L, Hannan Natalie J, Salamonsen Lois A, Rombauts Luk

Source: Reproductive Biology and Endocrinology, Vol 5, Iss 1, p 18 (2007)

Subject Terms: Gynecology and obstetrics, RG1-991, Reproduction, QH471-489

File Description: electronic resource

Relation: http://www.rbej.com/content/5/1/18; https://doaj.org/toc/1477-7827

Access URL: https://doaj.org/article/00afd8c9a26d4f609bc3279b8c5bb640

The Orphan Nuclear Receptor LRH-1 and ERα Activate GREB1 Expression to Induce Breast Cancer Cell Proliferation.

Authors: Chand, Ashwini L.¹ colin.clyne@princehenrys.org, Wijayakumara, Dhilushi D.¹, Knower, Kevin C.¹, Herridge, Kerrie A.¹, Howard, Tamara L.¹, Lazarus, Kyren A.¹, Clyne, Colin D.¹

Source: PLoS ONE. Feb2012, Vol. 7 Issue 2, p1-10. 10p.

Subject Terms: *NUCLEAR receptors (Biochemistry), *GENE expression, *BREAST cancer, *AROMATASE, *CELL cycle

Company/Entity: GENE Express Inc.

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Oestradiol reduces Liver Receptor Homolog-1 mRNA transcript stability in breast cancer cell lines

Authors: Lazarus, Kyren A., Zhao, Zhe, Knower, Kevin C., To, Sarah Q., Chand, Ashwini L., Clyne, Colin D.

Source: In Biochemical and Biophysical Research Communications 30 August 2013 438(3):533-539

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Mutational analysis of betaglycan/ TGF-βRIII in premature ovarian failure

Authors: Chand, Ashwini L., Robertson, David M., Shelling, Andrew N., Harrison, Craig A.

Source: In Fertility and Sterility 2007 87(1):210-212