Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers

Authors: Champiat, Stephane ^{1, 13, 15, ∗}, Garralda, Elena ², Galvao, Vladimir ², Cassier, Philippe A. ³, Gomez-Roca, Carlos ⁴, Korakis, Iphigenie ⁴, Grell, Peter ⁵, Naing, Aung ⁶, LoRusso, Patricia ⁷, Mikyskova, Romana ⁸, Podzimkova, Nada ⁹, Reinis, Milan ⁸, Ouali, Kaissa ¹, Schoenenberger, Andreu ⁹, Kiemle-Kallee, Joachim ¹⁰, Tillmanns, Sascha ¹⁰, Sachse, Richard ¹⁰, Moebius, Ulrich ⁹, Spisek, Radek ⁹, Bechard, David ¹¹, Jelinkova, Lenka Palova ^{9, 12, 14}, Adkins, Irena ^{9, 12, 14}, Marabelle, Aurelien ^{1, 14}

Source: In Cell Reports Medicine 18 February 2025 6(2)

Reactions and adverse events induced by T-cell engagers as anti-cancer immunotherapies, a comprehensive review

Authors: Géraud, Arthur, Hueso, Thomas, Laparra, Ariane, Bige, Naike, Ouali, Kaissa, Cauquil, Cécile, Stoclin, Annabelle, Danlos, François-Xavier, Hollebecque, Antoine, Ribrag, Vincent, Gazzah, Anas, Goldschmidt, Vincent, Baldini, Capucine, Suzzoni, Steve, Bahleda, Rastislav, Besse, Benjamin, Barlesi, Fabrice, Lambotte, Olivier, Massard, Christophe, Marabelle, Aurélien, Castilla-Llorente, Cristina, Champiat, Stéphane, Michot, Jean-Marie

Source: In European Journal of Cancer July 2024 205

Toxicity of immunotherapy combinations with chemotherapy across tumor indications: Current knowledge and practical recommendations

Authors: Rached, Layal, Laparra, Ariane, Sakkal, Madona, Danlos, François-Xavier, Barlesi, Fabrice, Carbonnel, Franck, De Martin, Eleonora, Ducreux, Michel, Even, Caroline, Le Pavec, Jerome, Michot, Jean-Marie, M. Ribeiro, Joana, Scotte, Florian, Ponce Aix, Santiago, Lambotte, Olivier, Baldini, Capucine, Champiat, Stéphane

Source: In Cancer Treatment Reviews June 2024 127

Ocular surface toxicities associated with modern anticancer therapies

Authors: Boucher, Rafael ^{a, b}, Haigh, Oscar ^b, Barreau, Emmanuel ^a, Champiat, Stéphane ^c, Lambotte, Olivier ^{b, d}, Adam, Clovis ^e, Labetoulle, Marc ^{a, b}, Rousseau, Antoine ^{a, b, ⁎}

Source: In Survey of Ophthalmology March-April 2024 69(2):198-210

Antibody drug conjugates in older patients: State of the art

Authors: Rached, Layal, Geraud, Arthur, Frelaut, Maxime, AP Thomas, Zoe, Goldschmidt, Vincent, Beraud-Chaulet, Geoffroy, Nagera-Lazarovici, Celine, Danlos, Francois-Xavier, Henon, Clemence, Parisi, Claudia, Gazzah, Anas, Bahleda, Rastilav, Postel Vinay, Sophie, Smolenschi, Cristina, Hollebecque, Antoine, Michot, Jean-Marie, Ribrag, Vincent, Loriot, Yohann, Champiat, Stephane, Ouali, Kaissa, Massard, Christophe, Ponce Aix, Santiago, Bringuier, Michael, Baldini, Capucine

Source: In Critical Reviews in Oncology / Hematology January 2024 193

Profile and outcome of cancer patients enrolled in contemporary phase I trials

Authors: Alouani, Emily, Gazzah, Anas, Mercier, Sandrine, Bahleda, Ratislav, Hollebecque, Antoine, Michot, Jean-Marie, Baldini, Capucine, Ammari, Samy, Champiat, Stephane, Marabelle, Aurelien, Postel-Vinay, Sophie, Ribrag, Vincent, Loriot, Yohann, Aix, Santiago Ponce, Mahjoubi, Linda

Source: European journal of cancer. 188:1-7

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194170553.0x000001&indx=1&recIds=ETOCvdc_100194170553.0x000001

Protective effect of obesity on survival in cancers treated with immunotherapy vanishes when controlling for type of cancer, weight loss and reduced skeletal muscle

Authors: Antoun, Sami, Lanoy, Emilie, Ammari, Samy, Farhane, Siham, Martin, Lisa, Robert, Caroline, Planchard, David, Routier, Emilie, Voisin, Anne Laure, Messayke, Sabine, Champiat, Stephane, Michot, Jean Marie, Laghouati, Salim, Lambotte, Olivier, Marabelle, Aurélien, Baracos, Vickie

Source: European journal of cancer. 178:49-59

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177957897.0x000001&indx=1&recIds=ETOCvdc_100177957897.0x000001

Immunosuppressant mycophenolate mofetil for patients with steroid-refractory immune-related hepatitis induced by checkpoint inhibitors in oncology

Authors: Alouani, Emily, Laparra, Ariane, Perret, Audrey, Sakkal, Madonna, Messayke, Sabine, Danlos, Francois-Xavier, Ouali, Kaissa, Hollebecque, Antoine, Even, Caroline, Ammari, Samy, Baldini, Capucine, Champiat, Stéphane, Besse, Benjamin, Robert, Caroline, Guettier, Catherine, Samuel, Didier, Lambotte, Olivier, De Martin, Eleonora, Michot, Jean-Marie

Source: In European Journal of Cancer November 2023 193

Immune-related generalised oedema – A new category of adverse events with immune checkpoint inhibitors

Authors: Velev, Maud, Baroudjian, Barouyr, Pruvost, Roxane, De Martin, Eleonora, Laparra, Ariane, Babai, Samy, Teysseire, Sandra, Danlos, François-Xavier, Albiges, Laurence, Bernigaud, Charlotte, Benderra, Marc-Antoine, Pradère, Pauline, Zaidan, Mohamad, Decroisette, Chantal, Fallah, Fatma, Matergia, Gaelle, Lavaud, Pernelle, Jantzem, Hélène, Atzenhoffer, Marina, Buyse, Véronique, Ammari, Samy, Robert, Caroline, Champiat, Stéphane, Messayke, Sabine, Marabelle, Aurélien, Guettier, Catherine, Lebbe, Céleste, Lambotte, Olivier, Michot, Jean-Marie

Source: In European Journal of Cancer January 2023 179:28-47

High serum LDH and liver metastases are the dominant predictors of primary cancer resistance to anti-PD(L)1 immunotherapy

Authors: Dercle, Laurent, Ammari, Samy, Roblin, Elvire, Bigorgne, Amelie, Champiat, Stéphane, Taihi, Lokmane, Plaian, Athèna, Hans, Sophie, Lakiss, Sara, Tselikas, Lambros, Rouanne, Mathieu, Deutsch, Eric, Schwartz, Lawrence H., Gönen, Mithat, Flynn, Jessica, Massard, Christophe, Soria, Jean-Charles, Robert, Caroline, Marabelle, Aurélien

Source: In European Journal of Cancer December 2022 177:80-93

Analysis of the association between prospectively collected immune-related adverse events and survival in patients with solid tumor treated with immune-checkpoint blockers, taking into account immortal-time bias

Authors: Kfoury, Maria, Najean, Marie, Lappara, Ariane, Voisin, Anne-Laure, Champiat, Stéphane, Michot, Jean-Marie, Laghouati, Salim, Robert, Caroline, Besse, Benjamin, Soria, Jean-Charles, Lambotte, Olivier, Massard, Christophe, Marabelle, Aurélien, Texier, Matthieu

Source: In Cancer Treatment Reviews November 2022 110

Paradoxical cancer cell stimulation by IFNγ drives tumor hyperprogression upon checkpoint blockade immunotherapy

Authors: Champiat, Stephane, Marabelle, Aurelien

Source: Cancer cell. 41(2):229-231

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183190242.0x000001&indx=1&recIds=ETOCvdc_100183190242.0x000001

Immunosenescence, inflammaging, and cancer immunotherapy efficacy

Authors: Rodriguez, Julieta E, Naigeon, Marie, Goldschmidt, Vincent, Roulleaux Dugage, Matthieu, Seknazi, Lauren, Danlos, Francois X, Champiat, Stephane, Marabelle, Aurélien, Michot, Jean-Marie, Massard, Christophe, Besse, Benjamin, Ferrara, Roberto, Chaput, Nathalie, Baldini, Capucine

Source: Expert review of anticancer therapy. 22(9):915-926

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165747511.0x000001&indx=1&recIds=ETOCvdc_100165747511.0x000001

Feasibility, safety and efficacy of human intra-tumoral immuno-therapy. Gustave Roussy's initial experience with its first 100 patients

Authors: Tselikas, Lambros, Dardenne, Antoine, de Baere, Thierry, Faron, Matthieu, Ammari, Samy, Farhane, Siham, Suzzoni, Steve, Danlos, François-Xavier, Raoult, Thibault, Susini, Sandrine, Al Shatti, Nael, Mouraud, Severine, Deschamps, Frédéric, Kobe, Adrian, Delpla, Alexandre, Roux, Charles, Baldini, Capucine, Soria, Jean-Charles, Barlesi, Fabrice, Massard, Christophe, Robert, Caroline, Champiat, Stéphane, Marabelle, Aurélien

Source: In European Journal of Cancer September 2022 172:1-12

Prognostic value of tumor immune biomarkers in biopsies from patients with refractory solid cancers

Authors: Lambert, Tiphaine, Pobel, Cedric, Colmet-Daage, Léo, Bigorgne, Amélie, RaubyY, Brice, Aladro, Nicolas Sanchez-Escobar, Ter-MinassianN, Lucile, Kerisit, Marie, Marabelle, Aurélien, Besse, Benjamin, Hollebecque, Antoine, Champiat, Stéphane, Massard, Christophe, Morel, Daphné, Verlingue, Loic, Scoazec, Jean-Yves

Source: In Cancer Treatment and Research Communications 2022 32

The determinants of very severe immune-related adverse events associated with immune checkpoint inhibitors: A prospective study of the French REISAMIC registry

Authors: Ruste, Valentine, Goldschmidt, Vincent, Laparra, Ariane, Messayke, Sabine, Danlos, Francois-Xavier, Romano-Martin, Patricia, Champiat, Stéphane, Voisin, Anne-Laure, Baldini, Capucine, Massard, Christophe, Laghouati, Salim, Marabelle, Aurélien, Lambotte, Olivier, Michot, Jean-Marie

Source: In European Journal of Cancer November 2021 158:217-224

Absence of significant clinical benefit for a systematic routine creatine phosphokinase measurement in asymptomatic patients treated with anti-programmed death protein (ligand) 1 immune checkpoint inhibitor to screen cardiac or neuromuscular immune-related toxicities

Authors: Hajem, Samia, Ederhy, Stéphane, Champiat, Stéphane, Troalen, Frédéric, Nolin-Lapalme, Alexis, Berhoune, Malik, Cauquil, Cécile, Martin-Romano, Patricia, Baldini, Capucine, Laparra, Ariane, Vuagnat, Perrine, Hollebecque, Antoine, Mateus, Christine, Besse, Benjamin, Naltet, Charles, Robert, Caroline, Marabelle, Aurélien, Massard, Christophe, Lambotte, Olivier, Michot, Jean-Marie

Source: In European Journal of Cancer November 2021 157:383-390

Outcomes of patients with cancer and sarcoid-like granulomatosis associated with immune checkpoint inhibitors: A case–control study

Authors: Cabanié, Charlotte, Ammari, Samy, Hans, Sophie, Pobel, Cedric, Laparra, Ariane, Danlos, Francois-Xavier, Chanson, Noémie, Dolidon, Samuel, Seban, Romain, Voisin, Anne-Laure, Pautier, Patricia, Romano-Martin, Patricia, Even, Caroline, Baldini, Capucine, Besse, Benjamin, Albiges, Laurence, Boutros, Celine, Routier, Emilie, Balleyguier, Corinne, De Montpreville, Vincent T., Champiat, Stéphane, Massard, Christophe, Robert, Caroline, Marabelle, Aurélien, Mateus, Christina, Lambotte, Olivier, Le Pavec, Jérôme, Michot, Jean-Marie

Source: In European Journal of Cancer October 2021 156:46-59

Impact de l’utilisation de la corticothérapie systémique sur l’efficacité des inhibiteurs de points de contrôle immunitaire

Alternate Title: Impact of the use of systemic corticosteroid therapy on the effectiveness of immune checkpoint inhibitors (English)

Authors: El Hazzaz, Reda, Kfoury, Maria, Lavaud, Pernelle, Marabelle, Aurélien, Champiat, Stéphane, Mellas, Nawfel, Besse, Benjamin, Massard, Christophe, Geraud, Arthur ^*

Source: In Bulletin du Cancer June 2021 108(6):635-642

Impact of Clonal Hematopoiesis–Associated Mutations in Phase I Patients Treated for Solid Tumors: An Analysis of the STING Trial.

Authors: Rodriguez, Julieta, Baldini, Capucine, Bayle, Arnaud, Pages, Arnaud, Danlos, François Xavier, Vasseur, Damien, Rouleau, Etienne, Lacroix, Ludovic, Alonso de Castro, Beatriz, Goldschmidt, Vincent, Seknazi, Lauren, Hollebecque, Antoine, Michot, Jean-Marie, Champiat, Stephane, Marabelle, Aurelien, Ouali, Kaissa, Marzac, Christophe, Ponce, Santiago, Micol, Jean-Baptiste, Chaput, Nathalie

Source: JCO Precision Oncology; 12/1/2024, Vol. 8, p1-13, 13p

Subject Terms: OVERALL survival, PROGRESSION-free survival, DRUG administration, GENE frequency, MEDICAL records