Gochujang suppresses cell survival and changes reactive oxygen species metabolism in colorectal cancer cells.

Authors: Eun-Bi Seo¹, So-Min Oh¹, Anna Han^1,2, annahan8659@jbnu.ac.kr

Source: Food & Nutrition Research; 2024, Vol. 68, p1-12, 12p

Fdo1, Fkh1, Fkh2, and the Swi6–Mbp1 MBF complex regulate Mcd1 levels to impact eco1 rad61 cell growth in Saccharomyces cerevisiae.

Authors: Singh, Gurvir¹, Skibbens, Robert V¹, rvs3@lehigh.edu

Source: Genetics; Oct2024, Vol. 228 Issue 2, p1-15, 15p

Development of New Diffuse Large B Cell Lymphoma Mouse Models.

Authors: Mehdi, Syed Hassan¹ (AUTHOR) shmehdi@uams.edu, Xu, Ying-Zhi² (AUTHOR) yxu2@uams.edu, Shultz, Leonard D.³ (AUTHOR) lenny.shultz@jax.org, Kim, Eunkyung¹ (AUTHOR) ekim@uams.edu, Lee, Yong Gu⁴ (AUTHOR) yglee1721@hanyang.ac.kr, Kendrick, Samantha² (AUTHOR) dyoon@uams.edu, Yoon, Donghoon¹ (AUTHOR) dyoon@uams.edu

Source: Cancers. Sep2024, Vol. 16 Issue 17, p3006. 12p.

Subject Terms: *BIOLOGICAL models, *RESEARCH funding, *CHALONES, *CELL proliferation, *DESCRIPTIVE statistics, *MICE, *CELL lines, *ANIMAL experimentation, *B cell lymphoma, *DISEASE progression, *INTERLEUKINS

The Disinfectant Effect of Modified Hydrothermal Nanotitania Extract on Candida albicans.

Authors: Noor, Nor Farid Mohd¹ (AUTHOR), Yusoff, Mohamad Ezany¹ (AUTHOR), Rahman, Mohd Azizi Abdul² (AUTHOR), Alam, Mohammad Khursheed³ (AUTHOR), Harun, Ahmad Mukifza⁴ (AUTHOR)

Source: BioMed Research International. 2/8/2021, p1-5. 5p.

Subject Terms: *CANDIDA albicans, *CHALONES, *CULTURE media (Biology), *DISINFECTION & disinfectants, *HUMAN growth, *NANOPARTICLES, *TITANIUM

Gremlin1: a BMP antagonist with therapeutic potential in Oncology.

Authors: Jin, Zhao, Cao, Yanshuo

Source: Investigational New Drugs; Dec2024, Vol. 42 Issue 6, p716-727, 12p

Subject Terms: THERAPEUTIC use of antineoplastic agents, CHALONES, CELLULAR signal transduction, BONE morphogenetic proteins, FIBROBLASTS, GENE expression, METASTASIS, TUMORS, CELL receptors, NEOVASCULARIZATION, EPIDERMAL growth factor receptors, CHEMICAL inhibitors

Melanoma Cells from Different Patients Differ in Their Sensitivity to Alpha Radiation-Mediated Killing, Sensitivity Which Correlates with Cell Nuclei Area and Double Strand Breaks.

Authors: Levy, Or I., Altaras, Anat, Binyamini, Lior, Sagi-Assif, Orit, Izraely, Sivan, Cooks, Tomer, Kobiler, Oren, Gerlic, Motti, Kelson, Itzhak, Witz, Isaac P., Keisari, Yona

Source: Cancers; Nov2024, Vol. 16 Issue 22, p3804, 25p

Subject Terms: SQUAMOUS cell carcinoma, IN vitro studies, IRINOTECAN, MELANOMA, CHALONES, DESCRIPTIVE statistics, DNA, ENZYMES, CELL cycle, CELL lines, CELL culture, PHYSICS, CELL nuclei, DNA damage, CELL death, CELL survival, SENSITIVITY & specificity (Statistics)

Use of a Mouse Model and Human Umbilical Vein Endothelial Cells to Investigate the Effect of Arsenic Exposure on Vascular Endothelial Function and the Associated Role of Calpains.

Authors: Zhihui Cai¹, Yanqing Zhang¹, Yutian Zhang¹, Xiaofeng Miao¹, Shu Li¹, Hui Yang¹, Qinjie Ling¹, Hoffmann, Peter R.², Zhi Huang¹ Thsh@jnu.edu.cn

Source: Environmental Health Perspectives. Jul2019, Vol. 127 Issue 7, p1-15. 15p. 5 Color Photographs, 1 Black and White Photograph, 1 Graph.

Subject Terms: *Animal experimentation, *Arsenic, *Organic compounds, *Water supply, *Environmental exposure, Capillary permeability, Cardiovascular diseases, Cell culture, Chalones, Endothelium, Flow cytometry, Fluorescent antibody technique, Low density lipoproteins, Mice, Polymerase chain reaction, Serum albumin, Statistics, Western immunoblotting, Phytochemicals, Data analysis, Cell survival, Descriptive statistics

FHL2 与LDHA相互作用促进胶质瘤细胞的增殖. (Chinese)

Alternate Title: FHL2 interacts with LDHA to promote glioma cell proliferation. (English)

Authors: 吴国庆, 张婷, 宋小锋, 朱婷, 李娜, 李明

Source: Chinese Journal of Cancer Biotherapy; Oct2024, Vol. 31 Issue 10, p976-983, 8p

Subject Terms: PROTEINS, COMPUTER-assisted molecular modeling, GLIOMAS, COLONY-forming units assay, LIQUID chromatography-mass spectrometry, PHOSPHORYLATION, CELL proliferation, NEUROGLIA, CHALONES, LACTATE dehydrogenase, DESCRIPTIVE statistics, GENE expression, CELL lines, SMALL molecules, WESTERN immunoblotting, LACTATES, PRECIPITIN tests

Okanin Inhibits Cell Growth and Induces Apoptosis and Pyroptosis in Oral Cancer.

Authors: Chia, Wei-Tso, Chen, Kuei-Yuan, Yang, Cheng-Yu, Hsieh, Cheng-Chih, Tsao, Chang-Huei, Lin, Chih-Kung, Peng, Bo, Ho, Sien-Lin, Chen, Yi-Ling, Chang, Szu-Chien, Chen, Yuan-Wu

Source: Cancers; Sep2024, Vol. 16 Issue 18, p3195, 13p

Subject Terms: METHYLENE blue, FLOW cytometry, MOUTH tumors, COLONY-forming units assay, T-test (Statistics), RESEARCH funding, FLAVONOIDS, APOPTOSIS, CHALONES, ENZYME-linked immunosorbent assay, IN vivo studies, CELL cycle, XENOGRAFTS, DESCRIPTIVE statistics, PLANT extracts, CELL lines, IMMUNOHISTOCHEMISTRY, MOLECULAR structure, WESTERN immunoblotting, STAINS & staining (Microscopy), CELL survival, COMPARATIVE studies, DATA analysis software, CASPASES

Long non‐coding RNA TMEM147 antisense RNA 1/microRNA‐124/signal transducer and activator of transcription 3 axis in estrogen receptor‐positive breast cancer.

Authors: Liang, Wei, Zhang, Xuanchang, Zhang, Jia, Xia, Haiyan, Wei, Xiaowei

Source: Journal of Obstetrics & Gynaecology Research; Sep2024, Vol. 50 Issue 9, p1604-1613, 10p

Subject Terms: FLOW cytometry, HORMONE receptor positive breast cancer, CARRIER proteins, TISSUES, RADIOIMMUNOASSAY, T-test (Statistics), DATA analysis, BREAST tumors, MICRORNA, CELL proliferation, CHALONES, REVERSE transcriptase polymerase chain reaction, DESCRIPTIVE statistics, ESTROGEN receptors, RNA probes, CELL lines, GENES, ONE-way analysis of variance, STATISTICS, STAT proteins, DATA analysis software, CELLS, CELL receptors

Resistance to Anti-HER2 Therapies in Gastrointestinal Malignancies.

Authors: Mo, Christiana, Sterpi, Michelle, Jeon, Hyein, Bteich, Fernand

Source: Cancers; Aug2024, Vol. 16 Issue 16, p2854, 22p

Subject Terms: GASTROINTESTINAL tumors, DRUG resistance in cancer cells, CELL proliferation, APOPTOSIS, CHALONES, CELLULAR signal transduction, NEOVASCULARIZATION inhibitors, GENE expression, ONCOGENES, CELL receptors

New alkaloids from Melodinus fusiformis and their cytotoxic activities.

Authors: Li, Peng-Fei¹ (AUTHOR), Cai, Hai-Min² (AUTHOR), Ran, Jun-Yan² (AUTHOR), Xue, Jie¹ (AUTHOR), Yin, Sha¹ (AUTHOR), Yin, Jiao¹ (AUTHOR), Luo, Jie¹ (AUTHOR), Guan, Huan-Yu^1,2 (AUTHOR) guanhuanyu630@163.com

Source: Fitoterapia. Mar2025, Vol. 181, pN.PAG-N.PAG. 1p.

Subject Terms: *ALKALOIDS, *CHALONES, *PHYTOCHEMICALS, *BIOLOGICAL products, *DESCRIPTIVE statistics, *CELL lines, *EXPERIMENTAL design, *MEDICINAL plants, *SPECTRUM analysis, *X-rays, *LEAVES, *COMPARATIVE studies, *DRUG discovery

Promotion of improved intestinal barrier health by soybean-derived bioactive peptides in Chinese mitten crab (Eriocheir sinensis) fed a low fishmeal diet.

Authors: Jiang, Kemeng¹, Liu, Bo^1,2,3, liub@ffrc.cn, Sun, Cunxin^1,2,3, liub@ffrc.cn, Zhou, Qunlan^1,2,3, Zheng, Xiaochuan^1,2,3, Liu, Mingyang^1,2,3, Xu, Gangchun^1,2, Jin, Wu^1,2, Tian, Hongyan⁴, Hu, He⁵

Source: British Journal of Nutrition; 3/28/2024, Vol. 131 Issue 6, p974-986, 13p

Long Noncoding RNA RP11-278A23.1, a Potential Modulator of p53 Tumor Suppression, Contributes to Colorectal Cancer Progression.

Authors: Kamikokura, Masayo¹ (AUTHOR) k-masayo@sapmed.ac.jp, Tange, Shoichiro¹ (AUTHOR) stange@sapmed.ac.jp, Nakase, Hiroshi² (AUTHOR) hiro_nakase@sapmed.ac.jp, Tokino, Takashi¹ (AUTHOR) tokino@sapmed.ac.jp, Idogawa, Masashi^1,2 (AUTHOR) idogawa@sapmed.ac.jp

Source: Cancers. Mar2024, Vol. 16 Issue 5, p882. 14p.

Subject Terms: *RESEARCH funding, *APOPTOSIS, *CHALONES, *COLORECTAL cancer, *RNA, *TUMOR suppressor genes, *GENES, *GENE expression profiling, *WESTERN immunoblotting, *SURVIVAL analysis (Biometry), *GENETIC mutation, *GENOMES, *DISEASE progression

New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in Saccharomyces cerevisiae.

Authors: Vandermeulen, Matthew D.¹, Cullen, Paul J.¹, pjcullen@buffalo.edu

Source: Genetics; Sep2020, Vol. 216 Issue 1, p95-116, 22p

Effects of essential oil of Origanum onites and its major component carvacrol on the expression of toxicity pathway genes in HepG2 cells.

Authors: Tomsuk, Özlem, Kuete, Victor, Sivas, Hülya, Kürkçüoğlu, Mine

Source: BMC Complementary Medicine & Therapies; 7/11/2024, Vol. 24 Issue 1, p1-16, 16p

Subject Terms: DNA analysis, HEPATOTOXICOLOGY, T-test (Statistics), RESEARCH funding, ESSENTIAL oils, TERPENES, CHALONES, ANTINEOPLASTIC agents, CELL proliferation, POLYMERASE chain reaction, CELLULAR signal transduction, PLANT extracts, GENE expression, EXPERIMENTAL design, CELL lines, REACTIVE oxygen species, PHENOLS, MOLECULAR structure, ONE-way analysis of variance, DATA analysis software, HEPATOCELLULAR carcinoma, SEQUENCE analysis, PHARMACODYNAMICS

Citral in lemon myrtle, lemongrass, litsea, and melissa essential oils suppress the growth and invasion of breast cancer cells.

Authors: Nagata, Takuya, Satou, Tadaaki, Hayashi, Shinichiro, Satyal, Prabodh, Watanabe, Manabu, Riggs, Brannick, Saida, Yoshihisa

Source: BMC Complementary Medicine & Therapies; 6/3/2024, Vol. 24 Issue 1, p1-12, 12p

Subject Terms: THERAPEUTIC use of antineoplastic agents, DATA analysis, RESEARCH funding, ESSENTIAL oils, BREAST tumors, CELL proliferation, CHALONES, APOPTOSIS, IMMUNODIAGNOSIS, CELL motility, PLANT extracts, CELL lines, CELL culture, GAS chromatography, ONE-way analysis of variance, STATISTICS, LEMONGRASS, BIOLOGICAL assay, DATA analysis software, COMPARATIVE studies, LEMON balm, CELL surface antigens

mTOR mutation disrupts larval zebrafish tail fin regeneration via regulating proliferation of blastema cells and mitochondrial functions.

Authors: Xiao, Gongyi, Li, Xiangwei, Yang, Huiping, Zhang, Ruobin, Huang, Junlan, Tian, Yu, Nie, Mao, Sun, Xianding

Source: Journal of Orthopaedic Surgery & Research; 5/29/2024, Vol. 19 Issue 1, p1-15, 15p

Subject Terms: MITOCHONDRIAL physiology, FISH anatomy, ORGANS (Anatomy), RESEARCH funding, CHALONES, APOPTOSIS, CELLULAR signal transduction, INSECT larvae, REGENERATION (Biology), ANIMAL experimentation, GENOME editing, TECHNOLOGY, GENETIC mutation

Reappraisal of the Roles of the Sonic Hedgehog Signaling Pathway in Hepatocellular Carcinoma.

Authors: Jeng, Kuo-Shyang, Chang, Chiung-Fang, Tsang, Yuk-Ming, Sheen, I-Shyan, Jeng, Chi-Juei

Source: Cancers; May2024, Vol. 16 Issue 9, p1739, 18p

Subject Terms: CELL migration inhibition, HEDGEHOG signaling proteins, CANCER relapse, LIGANDS (Chemistry), CANCER invasiveness, CHALONES, CELLULAR signal transduction, TREATMENT effectiveness, SURGICAL complications, GASTRIC lavage, RESEARCH, HEPATOCELLULAR carcinoma, CELL receptors, DISEASE progression, EVALUATION

Identification and In Vivo Validation of Unique Anti-Oncogenic Mechanisms Involving Protein Kinase Signaling and Autophagy Mediated by the Investigational Agent PV-10.

Authors: Tran, Son, Sipila, Patrick, Thakur, Satbir, Zhang, Chunfen, Narendran, Aru

Source: Cancers; Apr2024, Vol. 16 Issue 8, p1520, 11p

Subject Terms: PROTEINS, CELL migration inhibition, PROTEIN kinases, AUTOPHAGY, RESEARCH funding, INVESTIGATIONAL drugs, ANTINEOPLASTIC agents, BREAST tumors, HEAD & neck cancer, CHALONES, CELLULAR signal transduction, IN vivo studies, COLORECTAL cancer, IMMUNODIAGNOSIS, TUMOR markers, CELL lines, TUMOR suppressor genes, MICE, METASTASIS, RESEARCH methodology, ANIMAL experimentation, DRUG development, TESTIS tumors, CELL surface antigens, PHARMACODYNAMICS