Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease

Authors: Chakraborty, Saborni ^{1, 26}, Cheng, Bowie Yik-Ling ^{1, 26}, Edwards, Desmond L. ^{1, 2, 26}, Gonzalez, Joseph C. ^{1, 3, 26}, Chiu, David Kung-Chun ⁴, Zheng, Hong ¹, Scallan, Courtney ¹, Guo, Xinrong ¹, Tan, Gene S. ^{5, 6}, Coffey, Greg P. ⁷, Conley, Pamela B. ⁷, Hume, Patrick S. ^{8, 9}, Janssen, William J. ^{8, 9}, Byers, Derek E. ¹⁰, Mudd, Philip A. ^{11, 12}, Taubenberger, Jeffery ¹³, Memoli, Matthew ¹⁴, Davis, Mark M. ^{1, 2, 3, 15}, Chua, Katrin F. ^{16, 17}, Diamond, Michael S. ^{18, 19, 20, 21, 22}, Andreakos, Evangelos ²³, Khatri, Purvesh ^{1, 3, 24}, Wang, Taia T. ^{1, 2, 3, 25, 27, ∗}

Source: In Immunity 14 January 2025 58(1):182-196

Heterogeneity in IgG‐CD16 signaling in infectious disease outcomes*

Authors: Gonzalez, Joseph C., Chakraborty, Saborni, Thulin, Natalie K., Wang, Taia T.

Source: Immunological reviews. 309(1):64-74

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100160616992.0x000001&indx=1&recIds=ETOCvdc_100160616992.0x000001

SARS-CoV-2 vaccines in advanced clinical trials: Where do we stand?

Authors: Chakraborty, Saborni, Mallajosyula, Vamsee, Tato, Cristina M., Tan, Gene S., Wang, Taia T.

Source: In Advanced Drug Delivery Reviews May 2021 172:314-338

Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses.

Authors: Mallajosyula, Vamsee¹, Chakraborty, Saborni^1,2, Sola, Elsa¹, Fong, Ryan Furuichi¹, Shankar, Vishnu³, Fei Gao¹, Burrell, Allison R.⁴, Gupta, Neha¹, Wagar, Lisa E.^1,5, Mischel, Paul S.^6,7, Capasso, Robson⁸, Staat, Mary A.⁴, Yueh-Hsiu Chien^1,9, Dekker, Cornelia L.^1,10, Wang, Taia T.^1,2, Davis, Mark M.^1,9,11 mmdavis@stanford.edu

Source: Science. 12/20/2024, Vol. 386 Issue 6728, p1389-1395. 7p. 4 Color Photographs.

Subject Terms: *INFLUENZA, *T cells, *AVIAN influenza, *SEASONAL influenza, *MONOZYGOTIC twins, *ANTIGENS

Protective efficacy of influenza group 2 hemagglutinin stem-fragment immunogen vaccines

Authors: Sutton, Troy, Chakraborty, Saborni, Mallajosyula, Vamsee, Lamirande, Elaine, Ganti, Ketaki, Bock, Kevin, Moore, Ian, Varadarajan, Raghavan, Subbarao, Kanta

Source: Npj vaccines. 2:1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114783444.0x000001&indx=1&recIds=ETOCvdc_100114783444.0x000001

Early immune markers of clinical, virological, and immunological outcomes in patients with COVID-19: a multiomics study.

Authors: Zicheng Hu, van der Ploeg, Kattria, Chakraborty, Saborni, Arunachalam, Prabhu S., Mori, Diego A. M., Jacobson, Karen B., Bonilla, Hector, Parsonnet, Julie, Andrews, Jason R., Holubar, Marisa, Subramanian, Aruna, Khosla, Chaitan, Maldonado, Yvonne, Hedlin, Haley, la Parte, Lauren de, Press, Kathleen, Ty, Maureen, Tan, Gene S., Blish, Catherine, Takahashi, Saki

Source: eLife; 10/14/2022, p1-24, 24p

Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity.

Authors: Chakraborty, Saborni, Gonzalez, Joseph C., Sievers, Benjamin L., Mallajosyula, Vamsee, Chakraborty, Srijoni, Dubey, Megha, Ashraf, Usama, Cheng, Bowie Yik-Ling, Kathale, Nimish, Tran, Kim Quyen Thi, Scallan, Courtney, Sinnott, Aanika, Cassidy, Arianna, Chen, Steven T., Gelbart, Terri, Gao, Fei, Golan, Yarden, Ji, Xuhuai, Kim-Schulze, Seunghee, Prahl, Mary

Source: Science Translational Medicine; 3/9/2022, Vol. 14 Issue 635, p1-12, 12p

Subject Terms: SARS-CoV-2, FC receptors, IMMUNOGLOBULINS, ANTIBODY formation, COVID-19, IMMUNE complexes, IMMUNOGLOBULIN G

Differential Peripheral Blood Glycoprotein Profiles in Symptomatic and Asymptomatic COVID-19.

Authors: Pickering, Chad, Zhou, Bo, Xu, Gege, Rice, Rachel, Ramachandran, Prasanna, Huang, Hector, Pham, Tho D., Schapiro, Jeffrey M., Cong, Xin, Chakraborty, Saborni, Edwards, Karlie, Reddy, Srinivasa T., Guirgis, Faheem, Wang, Taia T., Serie, Daniel, Lindpaintner, Klaus

Source: Viruses (1999-4915); Mar2022, Vol. 14 Issue 3, p553-553, 20p

Subject Terms: LIQUID chromatography-mass spectrometry, POST-translational modification, COVID-19 pandemic, COMMON cold, COVID-19, GLYCOPEPTIDES, PEPTIDES, ASYMPTOMATIC patients

Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses.

Authors: Sievers, Benjamin L., Chakraborty, Saborni, Xue, Yong, Gelbart, Terri, Gonzalez, Joseph C., Cassidy, Arianna G., Golan, Yarden, Prahl, Mary, Gaw, Stephanie L., Arunachalam, Prabhu S., Blish, Catherine A., Boyd, Scott D., Davis, Mark M., Jagannathan, Prasanna, Nadeau, Kari C., Pulendran, Bali, Singh, Upinder, Scheuermann, Richard H., Frieman, Matthew B., Vashee, Sanjay

Source: Science Translational Medicine; 3/2/2022, Vol. 14 Issue 634, p1-8, 8p

Subject Terms: SARS-CoV-2, SARS-CoV-2 Omicron variant, MEDICAL personnel, VIRAL antigens, BOOSTER vaccines

New-onset IgG autoantibodies in hospitalized patients with COVID-19.

Authors: Chang, Sarah Esther, Feng, Allan, Meng, Wenzhao, Apostolidis, Sokratis A., Mack, Elisabeth, Artandi, Maja, Barman, Linda, Bennett, Kate, Chakraborty, Saborni, Chang, Iris, Cheung, Peggie, Chinthrajah, Sharon, Dhingra, Shaurya, Do, Evan, Finck, Amanda, Gaano, Andrew, Geßner, Reinhard, Giannini, Heather M., Gonzalez, Joyce, Greib, Sarah

Source: Nature Communications; 9/14/2021, Vol. 12 Issue 1, p1-15, 15p

Subject Terms: AUTOANTIBODIES, COVID-19, IMMUNOGLOBULIN G, CYTOSKELETAL proteins, SYMPTOMS, HOSPITAL patients

CD8⁺ T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19.

Authors: Mallajosyula, Vamsee, Ganjavi, Conner, Chakraborty, Saborni, McSween, Alana M., Pavlovitch-Bedzyk, Ana Jimena, Wilhelmy, Julie, Nau, Allison, Manohar, Monali, Nadeau, Kari C., Davis, Mark M.

Source: Science Immunology; 2021, Vol. 6 Issue 61, p1-18, 18p

Proinflammatory IgG Fc structures in patients with severe COVID-19

Authors: Chakraborty, Saborni, Gonzalez, Joseph, Edwards, Karlie, Mallajosyula, Vamsee, Buzzanco, Anthony S., Sherwood, Robert, Buffone, Cindy, Kathale, Nimish, Providenza, Susan, Xie, Markus M., Andrews, Jason R., Blish, Catherine A., Singh, Upinder, Dugan, Haley, Wilson, Patrick C., Pham, Tho D., Boyd, Scott D., Nadeau, Kari C., Pinsky, Benjamin A., Zhang, Sheng, Memoli, Matthew J., Taubenberger, Jeffery K., Morales, Tasha, Schapiro, Jeffrey M., Tan, Gene S., Jagannathan, Prasanna, Wang, Taia T.

Source: Nature Immunology; January 2021, Vol. 22 Issue: 1 p67-73, 7p

TNFα-producing CD4+T cells dominate the SARS-CoV-2-specific T cell response in COVID-19 outpatients and are associated with durable antibodies

Authors: van der Ploeg, Kattria, Kirosingh, Adam S., Mori, Diego A.M., Chakraborty, Saborni, Hu, Zicheng, Sievers, Benjamin L., Jacobson, Karen B., Bonilla, Hector, Parsonnet, Julie, Andrews, Jason R., Press, Kathleen D., Ty, Maureen C., Ruiz-Betancourt, Daniel R., Parte, Lauren de la, Tan, Gene S., Blish, Catherine A., Takahashi, Saki, Rodriguez-Barraquer, Isabel, Greenhouse, Bryan, Singh, Upinder, Wang, Taia T., Jagannathan, Prasanna

Source: Cell Reports Medicine; 20220101, Issue: Preprints

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