Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins.

Authors: Thorwald, Max A, Sta Maria, Naomi S, Chakhoyan, Ararat, O'Day, Peggy A, Jacobs, Russell E, Zlokovic, Berislav, Finch, Caleb E

Source: Journal of Alzheimer's Disease; Feb2025, Vol. 103 Issue 4, p1180-1190, 11p

Subject Terms: PROTEIN precursors, ALZHEIMER'S disease, IRON proteins, MAGNETIC resonance imaging, IRON chelates

Simultaneous Mapping of Vasculature, Hypoxia, and Proliferation Using Dynamic Susceptibility Contrast MRI, ^1^8F-FMISO PET, and ^1^8F-FLT PET in Relation to Contrast Enhancement in Newly Diagnosed Glioblastoma

Authors: Collet, Solène, Guillamo, Jean-Sébastien, Berro, David Hassanein, Chakhoyan, Ararat, Constans, Jean-Marc, Lechapt-Zalcman, Emmanuèle, Derlon, Jean-Michel, Hatt, Mathieu, Visvikis, Dimitris, Guillouet, Stéphane

Source: Journal of nuclear medicine. 62(10):1349-1356

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Magnetic resonance imaging of hypoxia in acute stroke compared with fluorine‐18 fluoromisonidazole‐positron emission tomography: A cross‐validation study?

Authors: Valable, Samuel, Toutain, Jérôme, Divoux, Didier, Chazalviel, Laurent, Corroyer‐Dulmont, Aurélien, Chakhoyan, Ararat, Guillouet, Stéphane, Bernaudin, Myriam, Barbier, Emmanuel L., Touzani, Omar

Source: NMR in biomedicine. 36(3)

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Air pollution amyloidogenesis is attenuated by the gamma‐secretase modulator GSM‐15606.

Authors: Godoy‐Lugo, Jose A., Thorwald, Max A., Cacciottolo, Mafalda, D'Agostino, Carla, Chakhoyan, Ararat, Sioutas, Constantinos, Tanzi, Rudolph E., Rynearson, Kevin D., Finch, Caleb E.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Sep2024, Vol. 20 Issue 9, p6107-6114, 8p

pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI)

Authors: Ellingson, Benjamin M., Yao, Jingwen, Raymond, Catalina, Chakhoyan, Ararat, Khatibi, Kasra, Salamon, Noriko, Villablanca, J. Pablo, Wanner, Ina, Real, Courtney R., Laiwalla, Azim, McArthur, David L., Monti, Martin M., Hovda, David A., Vespa, Paul M.

Source: In NeuroImage: Clinical 2019 22

Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry

Authors: Chakhoyan, Ararat, Yao, Jingwen, Leu, Kevin, Pope, Whitney, Salamon, Noriko, Yong, William, Lai, Albert, Nghiemphu, Phioanh, Everson, Richard, Prins, Robert, Liau, Linda, Nathanson, David, Cloughesy, Timothy, Ellingson, Benjamin

Source: Scientific reports. 9(1):1-8

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Probabilistic independent component analysis of dynamic susceptibility contrast perfusion MRI in metastatic brain tumors

Authors: Chakhoyan, Ararat, Raymond, Catalina, Chen, Jason, Goldman, Jodi, Yao, Jingwen, Kaprealian, Tania, Pouratian, Nader, Ellingson, Benjamin

Source: Cancer imaging. 19(1):1-11

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PH-weighted amine chemical exchange saturation transfer echoplanar imaging (CEST-EPI) as a potential early biomarker for bevacizumab failure in recurrent glioblastoma

Authors: Yao, Jingwen, Tan, Caleb Hock Pang, Schlossman, Jacob, Chakhoyan, Ararat, Raymond, Catalina, Pope, Whitney B., Salamon, Noriko, Lai, Albert, Ji, Matthew, Nghiemphu, Phioanh L., Liau, Linda M., Cloughesy, Timothy F., Ellingson, Benjamin M.

Source: Journal of neuro-oncology. 142(3):587-595

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127534733.0x000001&indx=1&recIds=ETOCvdc_100127534733.0x000001

Mono-exponential, diffusion kurtosis and stretched exponential diffusion MR imaging response to chemoradiation in newly diagnosed glioblastoma

Authors: Chakhoyan, Ararat, Woodworth, Davis C., Harris, Robert J., Lai, Albert, Nghiemphu, Phioanh L., Liau, Linda M., Pope, Whitney B., Cloughesy, Timothy F., Ellingson, Benjamin M.

Source: Journal of neuro-oncology. 139(3):651-659

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118723137.0x000001&indx=1&recIds=ETOCvdc_100118723137.0x000001

18F-FDOPA PET and MRI characteristics correlate with degree of malignancy and predict survival in treatment-naïve gliomas: a cross-sectional study

Authors: Patel, Chirag B., Fazzari, Elisa, Chakhoyan, Ararat, Yao, Jingwen, Raymond, Catalina, Nguyen, Huytram, Manoukian, Jasmine, Nguyen, Nhung, Pope, Whitney, Cloughesy, Timothy F., Nghiemphu, Phioanh L., Czernin, Johannes, Lai, Albert, Ellingson, Benjamin M.

Source: Journal of neuro-oncology. 139(2):399-409

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118723393.0x000001&indx=1&recIds=ETOCvdc_100118723393.0x000001

Simultaneous pH‐sensitive and oxygen‐sensitive MRI of human gliomas at 3 T using multi‐echo amine proton chemical exchange saturation transfer spin‐and‐gradient echo echo‐planar imaging (CEST‐SAGE‐EPI)

Authors: Harris, Robert J., Yao, Jingwen, Chakhoyan, Ararat, Raymond, Catalina, Leu, Kevin, Liau, Linda M., Nghiemphu, Phioanh L., Lai, Albert, Salamon, Noriko, Pope, Whitney B., Cloughesy, Timothy F., Ellingson, Benjamin M.

Source: Magnetic resonance in medicine. 80(5):1962-1978

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116453412.0x000001&indx=1&recIds=ETOCvdc_100116453412.0x000001

Editorial for 'MRI‐Based Investigation of Association Between Cerebrovascular Structural Alteration and White Matter Hyperintensity Induced by High Blood Pressure'

Authors: Huuskonen, Mikko T., Barisano, Giuseppe, Chakhoyan, Ararat, Zlokovic, Berislav V.

Source: Journal of magnetic resonance imaging. 54(5):1527-1528

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NIMG-15. DIFFERENTIATION OF IDH1 MUTANT AND WILD TYPE GLIOMAS USING pH- AND OXYGEN-SENSITIVE MOLECULAR MRI

Authors: Yao, Jingwen, Chakhoyan, Ararat, Ellingson, Benjamin, Pope, Whitney, Salamon, Noriko, Yong, William, Lai, Albert, Liau, Linda, Nghiemphu, Phioanh, Cloughesy, Timothy

Source: Neuro-oncology. 20(suppl 6):vi178-vi179

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094739603.0x000001&indx=1&recIds=ETOCvdc_100094739603.0x000001

Simultaneous mapping of vasculature, hypoxia and proliferation using DSC-MRI, ¹⁸F-FMISO PET, and ¹⁸F-FLT PET in relation to contrast enhancement in newly diagnosed glioblastoma.

Authors: Collet, Solène, Guillamo, Jean-Sébastien, Berro, David Hassanein, Chakhoyan, Ararat, Constans, Jean-marc, Lechapt-Zalcman, Emmanuèle, Derlon, Jean-Michel, Hatt, Mathieu, Visvikis, Dimitris, Guillouet, Stéphane, Perrio, Cécile, Bernaudin, Myriam, Valable, Samuel

Source: Journal of Nuclear Medicine; 8/1/2021, Vol. 62 Issue 8, p1-32, 32p

Cartographie simultanée de la vascularisation, de l’hypoxie et de la prolifération à l’aide de l’IRM de perfusion, la tep au 18f-fmiso et au 18f-flt, en relation avec la prise de contraste dans les glioblastomes

Authors: Berro, David Hassanein, Collet, Solène, Guillamo, Jean-Sébastien, Chakhoyan, Ararat, Constans, Jean-Marc, Lechapt-Zalcman, Emmanuèle, Derlon, Jean-Michel, Hatt, Mathieu, Visvikis, Dimitris, Guillouet, Stéphane, Perrio, Cécile, Bernaudin, Myriam, Valable, Samuel

Source: In Journal of Neuroradiology June 2021 48(4):230-231

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline.

Authors: Montagne, Axel, Nation, Daniel A., Sagare, Abhay P., Barisano, Giuseppe, Sweeney, Melanie D., Chakhoyan, Ararat, Pachicano, Maricarmen, Joe, Elizabeth, Nelson, Amy R., D'Orazio, Lina M., Buennagel, David P., Harrington, Michael G., Benzinger, Tammie L. S., Fagan, Anne M., Ringman, John M., Schneider, Lon S., Morris, John C., Reiman, Eric M., Caselli, Richard J., Chui, Helena C.

Source: Nature; 5/7/2020, Vol. 581 Issue 7806, p71-76, 6p, 3 Color Photographs, 1 Black and White Photograph, 3 Charts, 8 Graphs

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CMET-35. DIFFUSION AND PERFUSION FEATURES OF METASTATIC BRAIN LESIONS

Authors: Chakhoyan, Ararat, Raymond, Catalina, Chen, Jason, Goldman, Jodi, Karpealian, Tania, Pouratian, Nader, Ellingson, Benjamin

Source: Neuro-oncology. 20(suppl 6):vi61-vi61

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094743488.0x000001&indx=1&recIds=ETOCvdc_100094743488.0x000001