Tackling the unyielding: testing two novel approaches against NDM-producing Enterobacterales and Pseudomonas aeruginosa isolates collected in India

Authors: Yamuna Devi Bakthavatchalam, Bijayini Behera, Anand Shah, Purva Mathur, Raja Ray, Bashir Ahmed Fomda, Kamini Walia, Balaji Veeraraghavan

Source: Microbiology Spectrum, Vol 13, Iss 1 (2025)

Subject Terms: cefiderocol, cefepime/zidebactam, NDM, India, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/cf74ab7f841347cf91e695f2721d726d

In vitro antimicrobial activity of six novel β-lactam and β-lactamase inhibitor combinations and cefiderocol against NDM-producing Enterobacterales in China

Authors: Liu, Xinmeng ^{a, b, c, †}, Li, Ziyao ^{b, c, d, e, k, †}, Zhang, Feilong ^{a, b, c, †}, Yang, Xinrui ^{b, c, e}, Lei, Zichen ^{b, c, d, e}, Li, Chen ^{b, c, e, f}, Wu, Yongli ^{b, c, e}, Zhao, Jiankang ^{b, c}, Zhang, Yulin ^{b, c}, Hu, Yanning ^{a, b, c}, Shen, FangFang ^g, Wang, Pingbang ^h, Yang, Junwen ⁱ, Liu, Yulei ^j, Shi, Huihui ^l, Lu, Binghuai ^{a, b, c, d, e, ⁎}

Source: In International Journal of Antimicrobial Agents February 2025 65(2)

β-Lactam/β-Lactamase Inhibitor Combination Antibiotics Under Development

Authors: Angeliki Katsarou, Panagiotis Stathopoulos, Iva D. Tzvetanova, Christina-Maria Asimotou, Matthew E. Falagas

Source: Pathogens, Vol 14, Iss 2, p 168 (2025)

Subject Terms: antimicrobial resistance, metallo-β-lactamases, β-lactams/β-lactamase inhibitors, cefepime/zidebactam, cefepime/taniborbactam, imipenem/cilastatin/funobactam, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/14/2/168; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/6e0d1feda55040f396e59632f0990656

Compassionate use of a novel β-lactam enhancer-based investigational antibiotic cefepime/zidebactam (WCK 5222) for the treatment of extensively-drug-resistant NDM-expressing Pseudomonas aeruginosa infection in an intra-abdominal infection-induced sepsis patient: a case report

Authors: Dilip Dubey, Manish Roy, Tajamul H. Shah, Noor Bano, Vidushi Kulshrestha, Sandeep Mitra, Pushpender Sangwan, Madhulika Dubey, Ali Imran, Bhawna Jain, Aravind Velmurugan, Yamuna Devi Bakthavatchalam, Balaji Veeraraghavan

Source: Annals of Clinical Microbiology and Antimicrobials, Vol 22, Iss 1, Pp 1-6 (2023)

Subject Terms: Cefepime/zidebactam, β-lactam-enhancer, Pseudomonas, New-Delhi metallo-β-lactamase, Extensively-drug-resistant, Therapeutics. Pharmacology, RM1-950, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1476-0711

Access URL: https://doaj.org/article/508cd9903a834312bc0d7a2a8fd97068

In vitro activity of cefiderocol, cefepime/enmetazobactam, cefepime/zidebactam, eravacycline, omadacycline, and other comparative agents against carbapenem-non-susceptible Pseudomonas aeruginosa and Acinetobacter baumannii isolates associated from bloodstream infection in Taiwan between 2018–2020

Authors: Po-Yu Liu, Wen-Chien Ko, Wen-Sen Lee, Po-Liang Lu, Yen-Hsu Chen, Shu-Hsing Cheng, Min-Chi Lu, Chi-Ying Lin, Ting-Shu Wu, Muh-Yong Yen, Lih-Shinn Wang, Chang-Pan Liu, Pei-Lan Shao, Yu-Lin Lee, Zhi-Yuan Shi, Yao-Shen Chen, Fu-Der Wang, Shu-Hui Tseng, Chao-Nan Lin, Yu-Hui Chen, Wang-Huei Sheng, Chun-Ming Lee, Hung-Jen Tang, Po-Ren Hsueh

Source: Journal of Microbiology, Immunology and Infection, Vol 55, Iss 5, Pp 888-895 (2022)

Subject Terms: Cefepime/enmetazobactam, Cefepime/zidebactam, Cefiderocol, Omadacycline, Eravacycline, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1684118221001869; https://doaj.org/toc/1684-1182

Access URL: https://doaj.org/article/d34d33f2182440d0af50bfe0d5bbd14f

In Vitro Activity of New β-Lactam–β-Lactamase Inhibitor Combinations and Comparators against Clinical Isolates of Gram-Negative Bacilli: Results from the China Antimicrobial Surveillance Network (CHINET) in 2019

Authors: Yan Guo, Renru Han, Bo Jiang, Li Ding, Fengzhen Yang, Beijia Zheng, Yang Yang, Shi Wu, Dandan Yin, Demei Zhu, Fupin Hu

Source: Microbiology Spectrum, Vol 10, Iss 4 (2022)

Subject Terms: β-lactam–β-lactamase inhibitor combinations, difficult-to-treat resistance, cefepime-zidebactam, ceftazidime-avibactam, carbapenemase, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/c11e64b111644f86ad58ebacb42a9033