Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD

Authors: Shaowei Wang, Boyang Li, Jie Li, Zhiheng Cai, Cristelle Hugo, Yi Sun, Lu Qian, Julia TCW, Helena C. Chui, Dante Dikeman, Isaac Asante, Stan G. Louie, David A. Bennett, Zoe Arvanitakis, Alan T. Remaley, Bilal E. Kerman, Hussein N. Yassine

Source: Molecular Neurodegeneration, Vol 20, Iss 1, Pp 1-26 (2025)

Subject Terms: Alzheimer’s disease, Senescence, ABCA1, Caveolin-1, Cholesterol, Lysosome, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1326

Access URL: https://doaj.org/article/a54f42427b0941998a14c6fa6eba3077

Staphylococcus aureus can use an alternative pathway to be internalized by osteoblasts in absence of β1 integrins

Authors: Léo-Paul Tricou, William Mouton, Andréa Cara, Sophie Trouillet-Assant, Daniel Bouvard, Frédéric Laurent, Alan Diot, Jérôme Josse

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Staphylococcus aureus, Internalization, β1 integrin, Caveolin-1, Detergent-resistant membrane, Osteoblasts, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/43219f17f5b4416dbe0418f83e74c908

Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes?

Authors: Francesca Ruzzi, Chiara Cappello, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Olga Maria Pittino, Lorena Landuzzi, Arianna Palladini, Patrizia Nanni, Pier-Luigi Lollini

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-10 (2024)

Subject Terms: Lipid rafts, Caveolin-1, Human epidermal growth factor receptors, Target therapy resistance, Bone metastasis, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/0f01f19499ac4787836667014821c1c1

Nebulization of Hypoxic hUCMSC-EVs Attenuates Airway Epithelial Barrier Defects in Chronic Asthma Mice by Transferring CAV-1

Authors: Luo X, Wang Y, Mao Y, Xu X, Gu W, Li W, Mao C, Zheng T, Dong L

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 10941-10959 (2024)

Subject Terms: nebulization, hypo-evs, asthma, airway epithelial barrier, caveolin-1, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/nebulization-of-hypoxic-hucmsc-evs-attenuates-airway-epithelial-barrie-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/5e635cb4abce40ab8e2958424b38f592

CAV1 promotes epithelial-to-mesenchymal transition (EMT) and chronic renal allograft interstitial fibrosis by activating the ferroptosis pathway

Authors: Qianguang Han, Bin Ni, Wei Bao, Junqi Zhang, Ming Zheng, Jinxu Miu, Zijie Wang, Jingwen Yuan, Jun Tao, Zhijian Han, Min Gu, Xiaobing Ju, Ruoyun Tan

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: chronic renal graft dysfunction (CAD), epithelial-mesenchymal transition (EMT), ferroptosis, Caveolin-1(CAV1), Interleukin-6 (IL-6), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1523855/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f201ea63bf184367b43b2f290702ce75

Targeting Caveolin‐1 in Multiple Myeloma Cells Enhances Chemotherapy and Natural Killer Cell‐Mediated Immunotherapy

Authors: Dewen Zhan, Zhimin Du, Shang Zhang, Juanru Huang, Jian Zhang, Hui Zhang, Zhongrui Liu, Eline Menu, Jinheng Wang

Source: Advanced Science, Vol 12, Iss 4, Pp n/a-n/a (2025)

Subject Terms: caveolin‐1, glutathione metabolism, immunotherapy, multiple myeloma, natural killer cell, redox homeostasis, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/ed28d99c5bfc4ba4a87b9a96f11e7c7b

A water-soluble caveolin-1 peptide inhibits psoriasis-like skin inflammation by suppressing cytokine production and angiogenesis

Authors: Chika Asai, Naoko Takamura, Tomoya Watanabe, Miho Asami, Noriko Ikeda, Charles F. Reese, Stanley Hoffman, Yukie Yamaguchi

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Psoriasis, Skin inflammation, Caveolin-1, CSD peptide, water-soluble subregions, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/50b06ae0e3d641a0b9317dcdb509a433

Caveolin-1-mediated LDL transcytosis across endothelial cells in atherosclerosis

Authors: Zhang, Yifei ^{a, 1}, Jia, Xiong ^{a, b, 1}, Wang, Yayu ^{a, b}, Zheng, Qijun ^{a, ⁎}

Source: In Atherosclerosis March 2025 402

Glaesserella parasuis serotype 5 promotes pyroptosis via degrading Caveolin-1 in 3D4/21 cells

Authors: Lin, Huixing ^a, Zhang, Jianan ^a, Wang, Qing ^b, Zhou, Hong ^a, Fan, Hongjie ^{a, c, ⁎}

Source: In Veterinary Microbiology March 2025 302

Exosome-derived miR-107 targeting caveolin-1 promotes gallstone progression by regulating the hepatobiliary cholesterol secretion pathway

Authors: Wang, Xinxing ^{a, 1}, Ma, Mingze ^{b, 1}, Zhu, Lichao ^c, Qin, Chuan ^d, Shao, Shuai ^a, Xu, Xianwen ^a, Gao, Ruxin ^a, Zhang, Zhenhai ^{d, ⁎}

Source: In Biochemical Pharmacology February 2025 232

Caveolin-1 protects against liver injury and lipid accumulation in alcoholic fatty liver via ferroptosis resistance

Authors: Xue, Weiju ^{a, b, c, d}, Guo, Ning ^{b, c, d}, Shan, Liang ^a, Zhang, Zhengsheng ^a, Sun, Yuquan ^{b, c, d}, Wang, Yong ^{b, c, d}, Fang, Xing ^a, Liu, Xiuzhen ^a, Liu, Jianjun ^{a, ⁎}, Hu, Chengmu ^{b, c, d, ⁎⁎}

Source: In Molecular Immunology May 2025 181:53-65

Chronic intermittent hypobaric hypoxia prevents pulmonary arterial hypertension through maintaining eNOS homeostasis

Authors: Li, Hai-Shuang ^a, Liu, Hui-Jie ^a, Zhang, Yu ^a, Zhang, Jing ^a, Yan, Han-Yu ^a, Yuan, Wei-Cheng ^a, Wang, Sen ^a, Yu, Shuo ^a, Yang, Sheng-Qiang ^a, Sun, Meng-Wei ^a, Qi, Can-Yang ^a, Miao, Sui-Bing ^c, Zhang, Li-Ping ^a, Guo, Hui ^d, Zhang, Yi ^a, Ma, Hui-Jie ^{a, b, e, ⁎}, Guan, Yue ^{a, b, ⁎⁎}

Source: In Archives of Biochemistry and Biophysics May 2025 767

Cinobufagin disrupts the stability of lipid rafts by inhibiting the expression of caveolin-1 to promote non-small cell lung cancer cell apoptosis

Authors: Zhongqing Xu, Jinwei Li, Shuyu Fang, Mingzhu Lian, Changxiao Zhang, Jiahuan Lu, Kai Sheng

Source: Archives of Medical Science, Vol 20, Iss 3, Pp 887-908 (2024)

Subject Terms: non-small cell lung cancer, cinobufagin, lipid rafts, caveolin-1, Medicine

File Description: electronic resource

Relation: https://www.archivesofmedicalscience.com/Cinobufagin-disrupts-the-stability-of-lipid-rafts-by-inhibiting-the-expression-of,174578,0,2.html; https://doaj.org/toc/1734-1922; https://doaj.org/toc/1896-9151

Access URL: https://doaj.org/article/2df9d574647646af8ad37b89f852d840

SNX19 Interacts with Caveolin-1 and Flotillin-1 to Regulate D1R Endocytosis and Signaling

Authors: Bibhas Amatya, Jacob Q. M. Polzin, Van A. M. Villar, Jiang Yang, Prasad Konkalmatt, Xiaoyan Wang, Raisha C. Cadme, Peng Xu, John J. Gildea, Santiago Cuevas, Ines Armando, Robin A. Felder, Pedro A. Jose, Hewang Lee

Source: Biomedicines, Vol 13, Iss 2, p 481 (2025)

Subject Terms: caveolin-1, dopamine D1 receptor, flotillin-1, endocytosis, lipid raft, SNX19, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/13/2/481; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/4e6b3cf593bb4877af969dadf11e139a

Lack of AMP-activated protein kinase-α1 reduces nitric oxide synthesis in thoracic aorta perivascular adipose tissue

Authors: Hwej, Abdmajid ^{a, b}, Al-Ferjani, Ali ^{a, c}, Alshuweishi, Yazeed ^{d, e}, Naji, Abdullah ^{a, f}, Kennedy, Simon ^a, Salt, Ian P. ^{d, ⁎}

Source: In Vascular Pharmacology December 2024 157

Chemical characterization and effects of volatile oil of Alpinia zerumbet on the quality of collagen deposition and caveolin-1 expression in a muscular fibrosis murine model

Authors: Batista, T. S. C., Barros, G. S., Damasceno, F. C., Cândido, E. A. F., Batista, M. V. A.

Source: Brazilian Journal of Biology. January 2024 84

Subject Terms: fibrosis, Alpinia, volatile oil, Caveolin-1, gene expression

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842024000100147

TrxR1 is involved in the activation of Caspase-11 by regulating the oxidative-reductive status of Trx-1

Authors: Dongsheng Bai, Chen Zhou, Jiaying Du, Jiawei Zhao, Chunyang Gu, YuXiang Wang, Lulu Zhang, Na Lu, Yue Zhao

Source: Redox Biology, Vol 75, Iss , Pp 103277- (2024)

Subject Terms: TrxR, Thioredoxin-1, Caveolin-1, Outer membrane vesicle, Caspase-11, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231724002556; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/ffcf4808492c4988af195fd4e3a03c9f

The critical roles of caveolin-1 in lung diseases

Authors: Jiarun Fan, Siping Zheng, Maoping Wang, Xiaoliang Yuan

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: caveolin-1, pneumonia, asthma, COPD, ali, pulmonary hypertension, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1417834/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/9b8ad1b3668f4b2dbd4d7102db189ec7

Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells

Authors: Eleanor Martin, Rossana Girardello, Gunnar Dittmar, Alexander Ludwig

Source: eLife, Vol 13 (2024)

Subject Terms: caveolae, caveolin-1, proximity proteomics, APEX2, cell migration, membrane tension, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/85601; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/b9e2aa9f9c154711965280987fcdf78f

Mechanical stretch leads to increased caveolin-1 content and mineralization potential in extracellular vesicles from vascular smooth muscle cells

Authors: Mohammad Shaver, Kassandra Gomez, Katherine Kaiser, Joshua D. Hutcheson

Source: BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-12 (2024)

Subject Terms: Mechanical stretch, Extracellular vesicles, Caveolin-1, Calcification, Vascular smooth muscle cells, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2661-8850

Access URL: https://doaj.org/article/d3049e26385641fba3a71b51b8fd9349