Enhancing SIRT1 Gene Expression Using Small Activating RNAs: A Novel Approach for Reversing Metabolic Syndrome

Authors: Andrikakou, Pinelopi, Reebye, Vikash, Vasconcelos, Daniel, Yoon, Sorah, Voutila, Jon, George, Andrew J.T., Swiderski, Piotr, Habib, Robert, Catley, Matthew, Blakey, David, Habib, Nagy A., Rossi, John J., Huang, Kai-Wen

Source: Nucleic acid therapeutics. 32(6):486-496

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167392055.0x000001&indx=1&recIds=ETOCvdc_100167392055.0x000001

Delivery of Oligonucleotides to the Liver with GalNAc: From Research to Registered Therapeutic Drug

Authors: Debacker, Alexandre J., Voutila, Jon, Catley, Matthew, Blakey, David, Habib, Nagy

Source: In Molecular Therapy 5 August 2020 28(8):1759-1771

Patient stratification and the unmet need in asthma

Authors: Swedin, Linda, Saarne, Tiiu, Rehnberg, Maria, Glader, Pernilla, Niedzielska, Magdalena, Johansson, Gustav, Hazon, Petra, Catley, Matthew C.

Source: In Pharmacology and Therapeutics January 2017 169:13-34

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration

Authors: Smith, Bryan, Kiessling, Andrea, Lledo-Garcia, Rocio, Dixon, Kate L., Christodoulou, Louis, Catley, Matthew C., Atherfold, Paul, D'Hooghe, Lena E., Finney, Helene, Greenslade, Kevin, Hailu, Hanna, Kevorkian, Lara, Lightwood, Daniel, Meier, Christoph, Munro, Rebecca, Qureshi, Omar, Sarkar, Kaushik, Shaw, Sophie P., Tewari, Roohi, Turner, Alison, Tyson, Kerry, West, Shauna, Shaw, Stevan, Brennan, Frank R.

Source: MAbs. 10(7):1111-1130

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COPD monocytes demonstrate impaired migratory ability

Authors: Ravi, Arjun, Plumb, Jonathan, Gaskell, Rosemary, Mason, Sarah, Broome, Caroline, Booth, George, Catley, Matthew, Vestbo, Jørgen, Singh, Dave

Source: Respiratory research. 18(1):1-12

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Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 2

Authors: Kettle, Jason G., Åstrand, Annika, Catley, Matthew, Grimster, Neil P., Nilsson, Magnus, Su, Qibin, Woessner, Richard

Source: Expert opinion on therapeutic patents. 27(2):145-161

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106708640.0x000001&indx=1&recIds=ETOCvdc_100106708640.0x000001

Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1

Authors: Kettle, Jason G., Åstrand, Annika, Catley, Matthew, Grimster, Neil P., Nilsson, Magnus, Su, Qibin, Woessner, Richard

Source: Expert opinion on therapeutic patents. 27(2):127-143

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OX40 blockade inhibits house dust mite driven allergic lung inflammation in mice and in vitro allergic responses in humans

Authors: Burrows, Katie E., Dumont, Celine, Thompson, Clare L., Catley, Matthew C., Dixon, Kate L., Marshall, Diane

Source: European journal of immunology. 45(4):1116-1128

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163060009.0x000001&indx=1&recIds=ETOCvdc_100163060009.0x000001

Monoclonal antibodies for the treatment of asthma

Authors: Catley, Matthew C., Coote, Julie, Bari, Mohamed, Tomlinson, Kate L.

Source: In Pharmacology and Therapeutics 2011 132(3):333-351

Compositions and methods for inhibiting expression of IKK-B gene

Estrogen Receptor β: Expression Profile and Possible Anti-Inflammatory Role in Disease

Authors: Catley, Matthew C., Birrell, Mark A., Hardaker, Elizabeth L., de Alba, Jorge, Farrow, Stuart, Haj-Yahia, Saleem, Belvisi, Maria G. ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics July 2008 326(1):83-88

Novel Role for the Liver X Nuclear Receptor in the Suppression of Lung Inflammatory Responses

Authors: Birrell, Mark A., Catley, Matthew C., Hardaker, Elizabeth, Wong, Sissie, Willson, Timothy M., McCluskie, Kerryn, Leonard, Thomas, Farrow, Stuart N., Collins, Jon L., Haj-Yahia, Saleem ^**, Belvisi, Maria G.

Source: In Journal of Biological Chemistry 2 November 2007 282(44):31882-31890

Repression of Inflammatory Gene Expression in Human Pulmonary Epithelial Cells by Small-Molecule IκB Kinase Inhibitors

Authors: Newton, Robert ^*, Holden, Neil S., Catley, Matthew C., Oyelusi, Wale, Leigh, Richard, Proud, David, Barnes, Peter J.

Source: In The Journal of Pharmacology and Experimental Therapeutics May 2007 321(2):734-742

Compositions And Methods For Inhibiting Expression Of IKK-B Gene

Validation of the Anti-Inflammatory Properties of Small-Molecule IκB Kinase (IKK)-2 Inhibitors by Comparison with Adenoviral-Mediated Delivery of Dominant-Negative IKK1 and IKK2 in Human Airways Smooth Muscle

Authors: Catley, Matthew C., Sukkar, Maria B., Chung, K. Fan, Jaffee, Bruce, Liao, Sha-Mei, Coyle, Anthony J., Haddad, El-Bdaoui, Barnes, Peter J., Newton, Robert ^*

Source: In Molecular Pharmacology August 2006 70(2):697-705

IκB Kinase-2-Independent and -Dependent Inflammation in Airway Disease Models: Relevance of IKK-2 Inhibition to the Clinic

Authors: Birrell, Mark A., Wong, Sissie, Hardaker, Elizabeth L., Catley, Matthew C., McCluskie, Kerryn, Collins, Michael, Haj-Yahia, Saleem, Belvisi, Maria G. ^*

Source: In Molecular Pharmacology June 2006 69(6):1791-1800

Second-Generation Inhibitors Demonstrate the Involvement of p38 Mitogen-Activated Protein Kinase in Post-Transcriptional Modulation of Inflammatory Mediator Production in Human and Rodent Airways

Authors: Birrell, Mark A., Wong, Sissie, McCluskie, Kerryn, Catley, Matthew C., Hardaker, Elizabeth L., Haj-Yahia, Saleem, Belvisi, Maria G. ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics March 2006 316(3):1318-1327

COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF IKK-B GENE

Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of TH17 cell immunity

Authors: Lin, Chia-Hao, Wu, Cheng-Jang, Cho, Sunglim, Patkar, Rasika, Huth, William J., Lin, Ling-Li, Chen, Mei-Chi, Israelsson, Elisabeth, Betts, Joanne, Niedzielska, Magdalena, Patel, Shefali A., Duong, Han G., Gerner, Romana R., Hsu, Chia-Yun, Catley, Matthew, Maciewicz, Rose A., Chu, Hiutung, Raffatellu, Manuela, Chang, John T., Lu, Li-Fan

Source: Nature Immunology; 20230101, Issue: Preprints p1-13, 13p

Inhibitors of Protein Kinase C (PKC) Prevent Activated Transcription: ROLE OF EVENTS DOWNSTREAM OF NF-κB DNA BINDING

Authors: Catley, Matthew C. ^{‡, §, ¶}, Cambridge, Lisa M. ^{‡, §, ∥}, Nasuhara, Yasuyuki ^{‡, §}, Ito, Kazuhiro ^‡, Chivers, Joanna E. ^‡, Beaton, Andrew ^{‡, ∥}, Holden, Neil S. ^{**, ‡‡}, Bergmann, Martin W. ^{§§, ¶¶}, Barnes, Peter J. ^‡, Newton, Robert ^{‡, **, ∥∥}

Source: In Journal of Biological Chemistry 30 April 2004 279(18):18457-18466