Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation.

Authors: Michael L McHenry, Jason Simmons, Hyejeong Hong, LaShaunda L Malone, Harriet Mayanja-Kizza, William S Bush, W Henry Boom, Thomas R Hawn, Scott M Williams, Catherine M Stein

Source: PLoS Genetics, Vol 19, Iss 3, p e1010387 (2023)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/2e0843db2b3d420391bf11e8daa773b9

Differentially expressed transcript isoforms associate with resistance to tuberculin skin test and interferon gamma release assay conversion.

Authors: Jason D Simmons, R Max Segnitz, Kimberly A Dill-McFarland, Catherine M Stein, Glenna J Peterson, Harriet Mayanja-Kizza, W Henry Boom, Thomas R Hawn

Source: PLoS ONE, Vol 18, Iss 4, p e0284498 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0284498&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/18e905409be14fb8b0a6884e0c8d5dbf

Immune cells in bronchoalveolar lavage fluid of Ugandan adults who resist versus those who develop latent Mycobacterium tuberculosis infection.

Authors: Bonnie A Thiel, William Worodria, Sophie Nalukwago, Mary Nsereko, Ingvar Sanyu, Lalitha Rejani, Josephine Zawedde, David H Canaday, Catherine M Stein, Keith A Chervenak, LaShaunda L Malone, Ronald Kiyemba, Richard F Silver, John L Johnson, Harriet Mayanja-Kizza, W Henry Boom

Source: PLoS ONE, Vol 16, Iss 4, p e0249477 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249477&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1dc85d37d8f842fab88fbb40f511fb63

Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?

Authors: Michael L McHenry, Jacquelaine Bartlett, Robert P Igo, Eddie M Wampande, Penelope Benchek, Harriet Mayanja-Kizza, Kyle Fluegge, Noemi B Hall, Sebastien Gagneux, Sarah A Tishkoff, Christian Wejse, Giorgio Sirugo, W Henry Boom, Moses Joloba, Scott M Williams, Catherine M Stein

Source: PLoS Genetics, Vol 16, Iss 4, p e1008728 (2020)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/1f2b4f7ef2014e068b5e31f09d69b027

Genetic variability and consequence of Mycobacterium tuberculosis lineage 3 in Kampala-Uganda.

Authors: Eddie M Wampande, Peter Naniima, Ezekiel Mupere, David P Kateete, LaShaunda L Malone, Catherine M Stein, Harriet Mayanja-Kizza, Sebastien Gagneux, W Henry Boom, Moses L Joloba

Source: PLoS ONE, Vol 14, Iss 9, p e0221644 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b63eec520c404996bfb2cd37bf48413d

AmpliSeq transcriptome analysis of human alveolar and monocyte-derived macrophages over time in response to Mycobacterium tuberculosis infection.

Authors: Audrey C Papp, Abul K Azad, Maciej Pietrzak, Amanda Williams, Samuel K Handelman, Robert P Igo, Catherine M Stein, Katherine Hartmann, Larry S Schlesinger, Wolfgang Sadee

Source: PLoS ONE, Vol 13, Iss 5, p e0198221 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5976201?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e28290c5f68e46aa883fa2d95c42d8e0

A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa.

Authors: Rafal S Sobota, Catherine M Stein, Nuri Kodaman, Isaac Maro, Wendy Wieland-Alter, Robert P Igo, Albert Magohe, LaShaunda L Malone, Keith Chervenak, Noemi B Hall, Mecky Matee, Harriet Mayanja-Kizza, Moses Joloba, Jason H Moore, William K Scott, Timothy Lahey, W Henry Boom, C Fordham von Reyn, Scott M Williams, Giorgio Sirugo

Source: PLoS Genetics, Vol 13, Iss 6, p e1006710 (2017)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5495514?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/39b8f996319a481d8ac25d7c8934bd1c

Transcriptional networks are associated with resistance to Mycobacterium tuberculosis infection.

Authors: Chetan Seshadri, Nafiseh Sedaghat, Monica Campo, Glenna Peterson, Richard D Wells, Gregory S Olson, David R Sherman, Catherine M Stein, Harriet Mayanja-Kizza, Ali Shojaie, W Henry Boom, Thomas R Hawn, Tuberculosis Research Unit (TBRU)

Source: PLoS ONE, Vol 12, Iss 4, p e0175844 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/be1f5fc0e02c4c509ccb60eacd7db1ef

Associations of Toll-Like Receptor and β-Defensin Polymorphisms with Measures of Periodontal Disease (PD) in HIV+ North American Adults: An Exploratory Study.

Authors: Rajeev K Mehlotra, Noemi B Hall, Barne Willie, Catherine M Stein, Aaron Weinberg, Peter A Zimmerman, Lance T Vernon

Source: PLoS ONE, Vol 11, Iss 10, p e0164075 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5058471?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/79a490af0a864fb783e249272e5bc2e1

Importance of copy number variants in childhood apraxia of speech and other speech sound disorders

Authors: E. Ricky Chan, Penelope Benchek, Gabrielle Miller, Kim Brustoski, Ashleigh Schaffer, Barbara Truitt, Jessica Tag, Lisa Freebairn, Barbara A. Lewis, Catherine M. Stein, Sudha K. Iyengar

Source: Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/400fb69bb6e74c66b15212f4f8ec8dbd

Association of symptoms and severity of rift valley fever with genetic polymorphisms in human innate immune pathways.

Authors: Amy G Hise, Zachary Traylor, Noémi B Hall, Laura J Sutherland, Saidi Dahir, Megan E Ermler, Samuel Muiruri, Eric M Muchiri, James W Kazura, A Desirée LaBeaud, Charles H King, Catherine M Stein

Source: PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003584 (2015)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4355584?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/90d06a3312884e9ebda116f6c8a2cdda

Tuberculin skin test reversion following isoniazid preventive therapy reflects diversity of immune response to primary Mycobacterium tuberculosis infection.

Authors: Denise F Johnson, LaShaunda L Malone, Sarah Zalwango, Joy Mukisa Oketcho, Keith A Chervenak, Bonnie Thiel, Harriet Mayanja-Kizza, Catherine M Stein, W Henry Boom, Christina L Lancioni, Tuberculosis Research Unit

Source: PLoS ONE, Vol 9, Iss 5, p e96613 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096613&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/88be552e89134c5a91ca1d8fdce6414e

Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data.

Authors: Allison R Baker, Feiyou Qiu, April Kaur Randhawa, David J Horne, Mark D Adams, Muki Shey, Jill Barnholtz-Sloan, Harriet Mayanja-Kizza, Gilla Kaplan, Willem A Hanekom, W Henry Boom, Thomas R Hawn, Catherine M Stein, Tuberculosis Research Unit and South African Tuberculosis Vaccine Initiative Team

Source: PLoS ONE, Vol 7, Iss 10, p e47597 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3480404?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1234d6fa91e74d0c86ff9b89e355e15b

Genetic epidemiology of tuberculosis susceptibility: impact of study design.

Authors: Catherine M Stein

Source: PLoS Pathogens, Vol 7, Iss 1, p e1001189 (2011)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283783/pdf/?tool=EBI; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/4f060d22c67a47719511d29a1a72d1bf

Genome scan of M. tuberculosis infection and disease in Ugandans.

Authors: Catherine M Stein, Sarah Zalwango, LaShaunda L Malone, Sungho Won, Harriet Mayanja-Kizza, Roy D Mugerwa, Dmitry V Leontiev, Cheryl L Thompson, Kevin C Cartier, Robert C Elston, Sudha K Iyengar, W Henry Boom, Christopher C Whalen

Source: PLoS ONE, Vol 3, Iss 12, p e4094 (2008)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2605555?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d2e4e435bac74916a4dac69ae6249f32

Whole blood interferon-gamma responses to mycobacterium tuberculosis antigens in young household contacts of persons with tuberculosis in Uganda.

Authors: Deborah A Lewinsohn, Sarah Zalwango, Catherine M Stein, Harriet Mayanja-Kizza, Alphonse Okwera, W Henry Boom, Roy D Mugerwa, Christopher C Whalen

Source: PLoS ONE, Vol 3, Iss 10, p e3407 (2008)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2560997?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/15e89293535c417dbc4f7d9aec36e3b7

Epigenetic programming of host lipid metabolism associated with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis

Authors: Kimberly A. Dill-McFarland, Jason D. Simmons, Glenna J. Peterson, Felicia K. Nguyen, Monica Campo, Penelope Benchek, Catherine M. Stein, Tomas Vaisar, Harriet Mayanja-Kizza, W. Henry Boom, Thomas R. Hawn

Source: mSystems, Vol 9, Iss 9 (2024)

Subject Terms: Mycobacterium tuberculosis, DNA methylation, chromatin remodeling, interferons, monocytes, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/b5310dd7b1304cafaf2e9ec3f37e81f3

Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesis

Authors: Hyejeong Hong, Kimberly A. Dill-McFarland, Jason D. Simmons, Glenna J. Peterson, Penelope Benchek, Harriet Mayanja-Kizza, W. Henry Boom, Catherine M. Stein, Thomas R. Hawn

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: Mycobacterium tuberculosis, expression quantitative trait loci, monocyte response, proinflammatory cytokine, host-pathogen interactions, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359178/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a0aa5ef9a6bd430e8e6bb1cdca54ddd9

Capturing Recent Mycobacterium tuberculosis Infection by Tuberculin Skin Test vs. Interferon-Gamma Release Assay

Authors: Jesús Gutierrez, Mary Nsereko, LaShaunda L. Malone, Harriet Mayanja-Kizza, Hussein Kisingo, W. Henry Boom, Charles M. Bark, Catherine M. Stein

Source: Tropical Medicine and Infectious Disease, Vol 9, Iss 4, p 81 (2024)

Subject Terms: tuberculosis, Mtb infection, tuberculin skin test, interferon-gamma release assay, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2414-6366/9/4/81; https://doaj.org/toc/2414-6366

Access URL: https://doaj.org/article/389539a8c8af4166b36ecc693c1d7ae5

Interaction between M. tuberculosis Lineage and Human Genetic Variants Reveals Novel Pathway Associations with Severity of TB

Authors: Michael L. McHenry, Eddie M. Wampande, Moses L. Joloba, LaShaunda L. Malone, Harriet Mayanja-Kizza, William S. Bush, W. Henry Boom, Scott M. Williams, Catherine M. Stein

Source: Pathogens, Vol 10, Iss 11, p 1487 (2021)

Subject Terms: tuberculosis severity, M. tuberculosis, population genetics, lineage-based GWAS, M. tuberculosis–human coevolution, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/10/11/1487; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/4ce8188910264aaebe58bdfde9f3c03f