Neutrophils restricted contribution of CCRL2 genetic variants to COVID-19 severity

Authors: Laffranchi, Mattia ^{a, b, ⁎, 2}, Paraboschi, Elvezia Maria ^{c, d, 2}, Bianchetto-Aguilera, Francisco ^e, Tamassia, Nicola ^e, Gasperini, Sara ^e, Gardiman, Elisa ^e, Piserà, Arianna ^a, Del Prete, Annalisa ^f, Invernizzi, Pietro ^{g, h}, Gismondi, Angela ^{a, b}, Mantovani, Alberto ^{c, d, i}, Cassatella, Marco A. ^e, Asselta, Rosanna ^{c, d, ⁎⁎, 1}, Sozzani, Silvano ^{a, b, 1}

Source: In Heliyon 15 January 2025 11(1)

Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors

Authors: Pettinella, Francesca, Mariotti, Barbara, Lattanzi, Chiara, Bruderek, Kirsten, Donini, Marta, Costa, Sara, Marini, Olivia, Iannoto, Giulia, Gasperini, Sara, Caveggion, Elena, Castellucci, Monica, Calzetti, Federica, Bianchetto-Aguilera, Francisco, Gardiman, Elisa, Giani, Matteo, Dusi, Stefano, Cantini, Maurizio, Vassanelli, Aurora, Pavone, Denise, Milella, Michele, Pilotto, Sara, Biondani, Pamela, Höing, Benedikt, Schleupner, Marie Carolin, Hussain, Timon, Hadaschik, Boris, Kaspar, Cordelia, Visco, Carlo, Tecchio, Cristina, Koenderman, Leo, Bazzoni, Flavia, Tamassia, Nicola, Brandau, Sven, Cassatella, Marco A., Scapini, Patrizia

Source: In Cell Reports Medicine 20 February 2024 5(2)

Neutrophils and their friends

Authors: Cassatella, Marco A., Nauseef, William M.

Source: Immunological reviews. 314(1):6-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194618966.0x000001&indx=1&recIds=ETOCvdc_100194618966.0x000001

Current knowledge on the early stages of human neutropoiesis

Authors: Calzetti, Federica, Finotti, Giulia, Cassatella, Marco A.

Source: Immunological reviews. 314(1):111-124

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182149719.0x000001&indx=1&recIds=ETOCvdc_100182149719.0x000001

Uncovering two neutrophil-committed progenitors that immediately precede promyelocytes during human neutropoiesis

Authors: Signoretto, Ilaria, Calzetti, Federica, Finotti, Giulia, Lonardi, Silvia, Balanzin, Camillo, Bianchetto-Aguilera, Francisco, Gasperini, Sara, Gardiman, Elisa, Castellucci, Monica, Russignan, Anna, Bonifacio, Massimiliano, Sica, Antonio, Vermi, William, Tecchio, Cristina, Scapini, Patrizia, Tamassia, Nicola, Cassatella, Marco A.

Source: Cellular & Molecular Immunology; March 2025, Vol. 22 Issue: 3 p316-329, 14p

Neutrophils Display Novel Partners of Cytosolic Proliferating Cell Nuclear Antigen Involved in Interferon Response in COVID-19 Patients

Authors: Pesenti, Lucie, de Oliveira Formiga, Rodrigo, Tamassia, Nicola, Gardiman, Elisa, Chable de La Héronnière, François, Gasperini, Sara, Chicher, Johana, Kuhn, Lauriane, Hammann, Philippe, Le Gall, Morgane, Saraceni-Tasso, Giovanni, Martin, Clémence, Hosmalin, Anne, Breckler, Magali, Hervé, Roxane, Decker, Patrice, Ladjemi, Maha Zohra, Pène, Frédéric, Burgel, Pierre-Régis, Cassatella, Marco A., Witko-Sarsat, Véronique

Source: Journal of Innate Immunity; February 2025, Vol. 17 Issue: 1 p154-175, 22p

Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8

Authors: Tamassia, Nicola, Bianchetto-Aguilera, Francisco, Gasperini, Sara, Polletti, Sara, Gardiman, Elisa, Ostuni, Renato, Natoli, Gioacchino, Cassatella, Marco A.

Source: In Cell Reports 18 May 2021 35(7)

On the Improper Use of the Term High-Density Neutrophils

Authors: Cassatella, Marco A., Scapini, Patrizia

Source: In Trends in Immunology December 2020 41(12):1059-1061

Biological Roles of Neutrophil-Derived Granule Proteins and Cytokines

Authors: Cassatella, Marco Antonio, Östberg, Nataliya K., Tamassia, Nicola, Soehnlein, Oliver

Source: In Trends in Immunology July 2019 40(7):648-664

Deciphering the fate of slan+‐monocytes in human tonsils by gene expression profiling

Authors: Bianchetto‐Aguilera, Francisco, Tamassia, Nicola, Gasperini, Sara, Calzetti, Federica, Finotti, Giulia, Gardiman, Elisa, Montioli, Riccardo, Bresciani, Debora, Vermi, William, Cassatella, Marco Antonio

Source: FASEB journal. 34(7):9269-9284

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107522131.0x000001&indx=1&recIds=ETOCvdc_100107522131.0x000001

Fast and Accurate Quantitative Analysis of Cytokine Gene Expression in Human Neutrophils by Reverse Transcription Real-Time PCR

Authors: Tamassia, Nicola, Cassatella, Marco A., Bazzoni, Flavia

Source: Methods in molecular biology. 2087:243-260

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622476433&indx=1&recIds=ETOCRN622476433

Human neutrophils activated by TLR8 agonists, with or without IFNγ, synthesize and release EBI3, but not IL‐12, IL‐27, IL‐35, or IL‐39

Authors: Cassatella, Marco A., Gardiman, Elisa, Arruda‐Silva, Fabio, Bianchetto‐Aguilera, Francisco, Gasperini, Sara, Bugatti, Mattia, Vermi, William, Larousserie, Frederique, Devergne, Odile, Tamassia, Nicola

Source: Journal of leukocyte biology. 108(5):1515-1526

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108595678.0x000001&indx=1&recIds=ETOCvdc_100108595678.0x000001

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Authors: Cossarizza, Andrea, Chang, Hyun‐Dong, Radbruch, Andreas, Acs, Andreas, Adam, Dieter, Adam‐Klages, Sabine, Agace, William W., Aghaeepour, Nima, Akdis, Mübeccel, Allez, Matthieu, Almeida, Larissa Nogueira, Alvisi, Giorgia, Anderson, Graham, Andrä, Immanuel, Annunziato, Francesco, Anselmo, Achille, Bacher, Petra, Baldari, Cosima T., Bari, Sudipto, Barnaba, Vincenzo, Barros‐Martins, Joana, Battistini, Luca, Bauer, Wolfgang, Baumgart, Sabine, Baumgarth, Nicole, Baumjohann, Dirk, Baying, Bianka, Bebawy, Mary, Becher, Burkhard, Beisker, Wolfgang, Benes, Vladimir, Beyaert, Rudi, Blanco, Alfonso, Boardman, Dominic A., Bogdan, Christian, Borger, Jessica G., Borsellino, Giovanna, Boulais, Philip E., Bradford, Jolene A., Brenner, Dirk, Brinkman, Ryan R., Brooks, Anna E. S., Busch, Dirk H., Büscher, Martin, Bushnell, Timothy P., Calzetti, Federica, Cameron, Garth, Cammarata, Ilenia, Cao, Xuetao, Cardell, Susanna L., Casola, Stefano, Cassatella, Marco A., Cavani, Andrea, Celada, Antonio, Chatenoud, Lucienne, Chattopadhyay, Pratip K., Chow, Sue, Christakou, Eleni, Čičin‐Šain, Luka, Clerici, Mario, Colombo, Federico S., Cook, Laura, Cooke, Anne, Cooper, Andrea M., Corbett, Alexandra J., Cosma, Antonio, Cosmi, Lorenzo, Coulie, Pierre G., Cumano, Ana, Cvetkovic, Ljiljana, Dang, Van Duc, Dang‐Heine, Chantip, Davey, Martin S., Davies, Derek, De Biasi, Sara, Del Zotto, Genny, Dela Cruz, Gelo Victoriano, Delacher, Michael, Della Bella, Silvia, Dellabona, Paolo, Deniz, Günnur, Dessing, Mark, Di Santo, James P., Diefenbach, Andreas, Dieli, Francesco, Dolf, Andreas, Dörner, Thomas, Dress, Regine J., Dudziak, Diana, Dustin, Michael, Dutertre, Charles‐Antoine, Ebner, Friederike, Eckle, Sidonia B. G., Edinger, Matthias, Eede, Pascale, Ehrhardt, Götz R.A., Eich, Marcus, Engel, Pablo, Engelhardt, Britta, Erdei, Anna, Esser, Charlotte, Everts, Bart, Evrard, Maximilien, Falk, Christine S., Fehniger, Todd A., Felipo‐Benavent, Mar, Ferry, Helen, Feuerer, Markus, Filby, Andrew, Filkor, Kata, Fillatreau, Simon, Follo, Marie, Förster, Irmgard, Foster, John, Foulds, Gemma A., Frehse, Britta, Frenette, Paul S., Frischbutter, Stefan, Fritzsche, Wolfgang, Galbraith, David W., Gangaev, Anastasia, Garbi, Natalio, Gaudilliere, Brice, Gazzinelli, Ricardo T., Geginat, Jens, Gerner, Wilhelm, Gherardin, Nicholas A., Ghoreschi, Kamran, Gibellini, Lara, Ginhoux, Florent, Goda, Keisuke, Godfrey, Dale I., Goettlinger, Christoph, González‐Navajas, Jose M., Goodyear, Carl S., Gori, Andrea, Grogan, Jane L., Grummitt, Daryl, Grützkau, Andreas, Haftmann, Claudia, Hahn, Jonas, Hammad, Hamida, Hämmerling, Günter, Hansmann, Leo, Hansson, Goran, Harpur, Christopher M., Hartmann, Susanne, Hauser, Andrea, Hauser, Anja E., Haviland, David L., Hedley, David, Hernández, Daniela C., Herrera, Guadalupe, Herrmann, Martin, Hess, Christoph, Höfer, Thomas, Hoffmann, Petra, Hogquist, Kristin, Holland, Tristan, Höllt, Thomas, Holmdahl, Rikard, Hombrink, Pleun, Houston, Jessica P., Hoyer, Bimba F., Huang, Bo, Huang, Fang‐Ping, Huber, Johanna E., Huehn, Jochen, Hundemer, Michael, Hunter, Christopher A., Hwang, William Y. K., Iannone, Anna, Ingelfinger, Florian, Ivison, Sabine M, Jäck, Hans‐Martin, Jani, Peter K., Jávega, Beatriz, Jonjic, Stipan, Kaiser, Toralf, Kalina, Tomas, Kamradt, Thomas, Kaufmann, Stefan H. E., Keller, Baerbel, Ketelaars, Steven L. C., Khalilnezhad, Ahad, Khan, Srijit, Kisielow, Jan, Klenerman, Paul, Knopf, Jasmin, Koay, Hui‐Fern, Kobow, Katja, Kolls, Jay K., Kong, Wan Ting, Kopf, Manfred, Korn, Thomas, Kriegsmann, Katharina, Kristyanto, Hendy, Kroneis, Thomas, Krueger, Andreas, Kühne, Jenny, Kukat, Christian, Kunkel, Désirée, Kunze‐Schumacher, Heike, Kurosaki, Tomohiro, Kurts, Christian, Kvistborg, Pia, Kwok, Immanuel, Landry, Jonathan, Lantz, Olivier, Lanuti, Paola, LaRosa, Francesca, Lehuen, Agnès, LeibundGut‐Landmann, Salomé, Leipold, Michael D., Leung, Leslie Y.T., Levings, Megan K., Lino, Andreia C., Liotta, Francesco, Litwin, Virginia, Liu, Yanling, Ljunggren, Hans‐Gustaf, Lohoff, Michael, Lombardi, Giovanna, Lopez, Lilly, López‐Botet, Miguel, Lovett‐Racke, Amy E., Lubberts, Erik, Luche, Herve, Ludewig, Burkhard, Lugli, Enrico, Lunemann, Sebastian, Maecker, Holden T., Maggi, Laura, Maguire, Orla, Mair, Florian, Mair, Kerstin H., Mantovani, Alberto, Manz, Rudolf A., Marshall, Aaron J., Martínez‐Romero, Alicia, Martrus, Glòria, Marventano, Ivana, Maslinski, Wlodzimierz, Matarese, Giuseppe, Mattioli, Anna Vittoria, Maueröder, Christian, Mazzoni, Alessio, McCluskey, James, McGrath, Mairi, McGuire, Helen M., McInnes, Iain B., Mei, Henrik E., Melchers, Fritz, Melzer, Susanne, Mielenz, Dirk, Miller, Stephen D., Mills, Kingston H.G., Minderman, Hans, Mjösberg, Jenny, Moore, Jonni, Moran, Barry, Moretta, Lorenzo, Mosmann, Tim R., Müller, Susann, Multhoff, Gabriele, Muñoz, Luis Enrique, Münz, Christian, Nakayama, Toshinori, Nasi, Milena, Neumann, Katrin, Ng, Lai Guan, Niedobitek, Antonia, Nourshargh, Sussan, Núñez, Gabriel, O'Connor, José‐Enrique, Ochel, Aaron, Oja, Anna, Ordonez, Diana, Orfao, Alberto, Orlowski‐Oliver, Eva, Ouyang, Wenjun, Oxenius, Annette, Palankar, Raghavendra, Panse, Isabel, Pattanapanyasat, Kovit, Paulsen, Malte, Pavlinic, Dinko, Penter, Livius, Peterson, Pärt, Peth, Christian, Petriz, Jordi, Piancone, Federica, Pickl, Winfried F., Piconese, Silvia, Pinti, Marcello, Pockley, A. Graham, Podolska, Malgorzata Justyna, Poon, Zhiyong, Pracht, Katharina, Prinz, Immo, Pucillo, Carlo E. M., Quataert, Sally A., Quatrini, Linda, Quinn, Kylie M., Radbruch, Helena, Radstake, Tim R. D. J., Rahmig, Susann, Rahn, Hans‐Peter, Rajwa, Bartek, Ravichandran, Gevitha, Raz, Yotam, Rebhahn, Jonathan A., Recktenwald, Diether, Reimer, Dorothea, Reis e Sousa, Caetano, Remmerswaal, Ester B.M., Richter, Lisa, Rico, Laura G., Riddell, Andy, Rieger, Aja M., Robinson, J. Paul, Romagnani, Chiara, Rubartelli, Anna, Ruland, Jürgen, Saalmüller, Armin, Saeys, Yvan, Saito, Takashi, Sakaguchi, Shimon, Sala‐de‐Oyanguren, Francisco, Samstag, Yvonne, Sanderson, Sharon, Sandrock, Inga, Santoni, Angela, Sanz, Ramon Bellmàs, Saresella, Marina, Sautes‐Fridman, Catherine, Sawitzki, Birgit, Schadt, Linda, Scheffold, Alexander, Scherer, Hans U., Schiemann, Matthias, Schildberg, Frank A., Schimisky, Esther, Schlitzer, Andreas, Schlosser, Josephine, Schmid, Stephan, Schmitt, Steffen, Schober, Kilian, Schraivogel, Daniel, Schuh, Wolfgang, Schüler, Thomas, Schulte, Reiner, Schulz, Axel Ronald, Schulz, Sebastian R., Scottá, Cristiano, Scott‐Algara, Daniel, Sester, David P., Shankey, T. Vincent, Silva‐Santos, Bruno, Simon, Anna Katharina, Sitnik, Katarzyna M., Sozzani, Silvano, Speiser, Daniel E., Spidlen, Josef, Stahlberg, Anders, Stall, Alan M., Stanley, Natalie, Stark, Regina, Stehle, Christina, Steinmetz, Tobit, Stockinger, Hannes, Takahama, Yousuke, Takeda, Kiyoshi, Tan, Leonard, Tárnok, Attila, Tiegs, Gisa, Toldi, Gergely, Tornack, Julia, Traggiai, Elisabetta, Trebak, Mohamed, Tree, Timothy I.M., Trotter, Joe, Trowsdale, John, Tsoumakidou, Maria, Ulrich, Henning, Urbanczyk, Sophia, Veen, Willem, Broek, Maries, Pol, Edwin, Van Gassen, Sofie, Van Isterdael, Gert, Lier, René A.W., Veldhoen, Marc, Vento‐Asturias, Salvador, Vieira, Paulo, Voehringer, David, Volk, Hans‐Dieter, Borstel, Anouk, Volkmann, Konrad, Waisman, Ari, Walker, Rachael V., Wallace, Paul K., Wang, Sa A., Wang, Xin M., Ward, Michael D., Ward‐Hartstonge, Kirsten A, Warnatz, Klaus, Warnes, Gary, Warth, Sarah, Waskow, Claudia, Watson, James V., Watzl, Carsten, Wegener, Leonie, Weisenburger, Thomas, Wiedemann, Annika, Wienands, Jürgen, Wilharm, Anneke, Wilkinson, Robert John, Willimsky, Gerald, Wing, James B., Winkelmann, Rieke, Winkler, Thomas H., Wirz, Oliver F., Wong, Alicia, Wurst, Peter, Yang, Jennie H. M., Yang, Juhao, Yazdanbakhsh, Maria, Yu, Liping, Yue, Alice, Zhang, Hanlin, Zhao, Yi, Ziegler, Susanne Maria, Zielinski, Christina, Zimmermann, Jakob, Zychlinsky, Arturo

Source: European journal of immunology. 49(10):1457-1973

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099939239.0x000001&indx=1&recIds=ETOCvdc_100099939239.0x000001

IL‐10‐producing B cells are characterized by a specific methylation signature

Authors: Tonon, Silvia, Mion, Francesca, Dong, Jun, Chang, Hyun‐Dong, Dalla, Emiliano, Scapini, Patrizia, Perruolo, Giuseppe, Zanello, Andrea, Dugo, Matteo, Cassatella, Marco A., Colombo, Mario P., Radbruch, Andreas, Tripodo, Claudio, Pucillo, Carlo E.

Source: European journal of immunology. 49(8):1213-1225

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087228612.0x000001&indx=1&recIds=ETOCvdc_100087228612.0x000001

Human neutrophils activated via TLR8 promote Th17 polarization through IL‐23

Authors: Tamassia, Nicola, Arruda‐Silva, Fabio, Wright, Helen L., Moots, Robert J., Gardiman, Elisa, Bianchetto‐Aguilera, Francisco, Gasperini, Sara, Capone, Manuela, Maggi, Laura, Annunziato, Francesco, Edwards, Steven W., Cassatella, Marco A.

Source: Journal of leukocyte biology. 105(6):1155-1165

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100082020928.0x000001&indx=1&recIds=ETOCvdc_100082020928.0x000001

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates

Authors: Cassetta, Luca, Baekkevold, Espen S., Brandau, Sven, Bujko, Anna, Cassatella, Marco A., Dorhoi, Anca, Krieg, Carsten, Lin, Ang, Loré, Karin, Marini, Olivia, Pollard, Jeffrey W., Roussel, Mikael, Scapini, Patrizia, Umansky, Viktor, Adema, Gosse J.

Source: Cancer immunology, immunotherapy. 68(4):687-697

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125514847.0x000001&indx=1&recIds=ETOCvdc_100125514847.0x000001

Impaired natural killer cell functions in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations

Authors: Tabellini, Giovanna, Vairo, Donatella, Scomodon, Omar, Tamassia, Nicola, Ferraro, Rosalba Monica, Patrizi, Ornella, Gasperini, Sara, Soresina, Annarosa, Giardino, Giuliana, Pignata, Claudio, Lougaris, Vassilios, Plebani, Alessandro, Dotta, Laura, Cassatella, Marco A., Parolini, Silvia, Badolato, Raffaele

Source: In The Journal of Allergy and Clinical Immunology August 2017 140(2):553-564

How murine neutrophils are hijacked within the microenvironment of pancreatic cancer.

Authors: Cassatella, Marco Antonio, Scapini, Patrizia, Tamassia, Nicola

Source: Journal of Leukocyte Biology; Apr2024, Vol. 115 Issue 4, p585-588, 4p

Subject Terms: PANCREATIC tumors, PANCREATIC cancer, NEUTROPHILS, TUMOR microenvironment, PANCREATIC duct, TUMOR growth

Human CD34^+/dim neutrophil-committed progenitors do not differentiate into neutrophil-like CXCR1⁺CD14⁺CD16⁻ monocytes in vitro.

Authors: Signoretto, Ilaria, Calzetti, Federica, Gasperini, Sara, Bianchetto-Aguilera, Francisco, Gardiman, Elisa, Finotti, Giulia, Tecchio, Cristina, Tamassia, Nicola, Cassatella, Marco A

Source: Journal of Leukocyte Biology; Apr2024, Vol. 115 Issue 4, p695-705, 11p

Subject Terms: MONOCYTES, NEUTROPHILS, FLOW cytometry, CD14 antigen, CD34 antigen

Mature CD10+ and immature CD10− neutrophils present in G-CSF–treated donors display opposite effects on T cells

Authors: Marini, Olivia, Costa, Sara, Bevilacqua, Dalila, Calzetti, Federica, Tamassia, Nicola, Spina, Cecilia, De Sabata, Donata, Tinazzi, Elisa, Lunardi, Claudio, Scupoli, Maria T., Cavallini, Chiara, Zoratti, Elisa, Tinazzi, Ilaria, Marchetta, Antonio, Vassanelli, Aurora, Cantini, Maurizio, Gandini, Giorgio, Ruzzenente, Andrea, Guglielmi, Alfredo, Missale, Francesco, Vermi, William, Tecchio, Cristina, Cassatella, Marco A., Scapini, Patrizia

Source: In Blood 9 March 2017 129(10):1343-1356