Safety and efficacy of nerinetide in patients with acute ischaemic stroke enrolled in the early window: a post-hoc meta-analysis of individual patient data from three randomised trials

Authors: Aamodt, Anne Hege, Adams, Corey, Adel, Brian A, Advani, Rajiv, Almekhlafi, Mohammed A, Asdaghi, Negar, Bailey, Peter, Bang, Oh Young, Benavente, Oscar, Berrouschot, Jorg, Bharatha, Aditya, Bode, Felix J, Bormann, Albrecht, Buck, Brian H, Budzik, Ronald F, Burns, Paul A, Caen, Marie-Christine, Campbell, Bruce C.V., Camden, Marie-Christine, Casaubon, Leanne K, Chandra, Ronil, Chapot, Rene, Cheskes, Sheldon, Chiu, Albert H.Y., Choe, Hana, Christenson, Jim, Cirillo, Luigi, Couthino, Jonathan M, Coutts, Shelagh B, Cutting, Shawna M, Da Costa, Leodante, Demchuk, Andrew M, Devlin, Michael, Dimitriadis, Konstantin, Dippel, Diedrick W.J, Dorn, Franziska, Dowlatshahi, Dar, Eltoft, Agnethe, English, Joey, Field, Thalia S, Fischer, Sebastian, Frei, Donald F, Fromme, Annette, Gandhi, Dheeraj, Ganesh, Aravind, Garcia-Bermejo, Pablo, Garman, J David, Ghia, Darshan, Goyal, Mayank, Gralla, Jan, Grossberg, Jonathan A, Gubitz, Gordon J, Gupta, Rishi, Guest, William C, Haeusler, Karl G, Hanel, Ricardo A, Harris, Cameron, Harris, Devin, Hassan, Ameer E, Haussen, Diogo, Heard, Kathy J, Heck, Donald, Hellstern, Victoria, Heo, Ji H, Hill, Michael D, Holmin, Staffan, Holtmannspoetter, Markus, Iancu, Daniela, Jansen, Olav, Jadhav, Ashutosh, Jenneson, Sandra, Jin, Albert, Joshi, Manish, Kelly, Michael E, Kleinig, Timothy J, Kohli, Yatika, Lee, Seon Kyu, Leroux, Michelle, Liebig, Thomas, Limbucci, Nicola, Lopez, George A, Lowerison, Mark W, Maegerlin, Christian, Maier, Ilko, Mandzia, Jennifer L, Martin, Coleman O, Mayor-Nunez, Diana, McDonough, Rosalie V, McDougall, Cameron G, McTaggart, Ryan A, Medvedev, George, Mehdiratta, Manu, Menon, Bijoy K, Michalski, Dominik, Minnerup, Jens, Morrison, Laurie J, Moussaddy, Aimen, Mundiyanapurath, Sibu, Murphy, Cynthia, Murphy, Seán, Muto, Mario, Nagel, Simon, Niesen, Wolf-Dirk, Nimjee, Shahid M, Nogueira, Raul G, Ospel, Johanna Maria, Pennington, Sarah, Perez, Yael, Pero, Guglielmo, Puetz, Volker, Pham, Mirko, Phillips, Stephen J, Poli, Sven, Poppe, Alexandre Y, Psychogios, Marios N, Puri, Ajit S, Reimann, Gernot, Rempel, Jeremy L, Remonda, Luca, Rha, Joung-Ho, Rocha, Marcello, Rohr, Axel CR, Roy, Daniel, Ryckborst, Karla J, Sahlas, Demetrios J, Sauvageau, Eric, Schneider, Hauke, Schoon, Bridget A, Selchen, Daniel, Shah, Ruchir A, Shankar, Jai J, Silver, Frank L, Skjelland, Mona, Sohn, Sung-Il, Starkman, Sidney, Stebner, Alexander, Swartz, Richard H, Tallon, John, Tarpley, Jason W, Teitelbaum, Jeanne, Tham, Carol Huilian, Thomalla, Götz, Thornton, John, Tkach, Aleksander, Turkel-Parella, David, Tymianski, Michael, van Adel, Brian A, van Doormaal, Pieter J, van Zwam, Wim, Verbeek, P Richard, Wiesmann, Martin, Witt, Karsten, Yeo, Leonard L.L., Yu, Amy Y X, Zafar, Atif, Zerna, Charlotte, Heard, Kathy ^e

Source: In The Lancet Neurology March 2025 24(3):208-217

Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial

Authors: Salluzzi, Marina, Blenkin, Nicole, Dueck, Ashley, Doram, Craig, Zhang, Qiao, Kenney, Carol, Ryckborst, Karla, Bohn, Shelly, Collier, Quentin, Taylor, Frances, Lethebe, B. Cord, Jambula, Anitha, Sage, Kayla, Toussaint, Lana, Save, Supryia, Lee, Jaclyn, Laham, N, Sultan, A.A., Deepak, A., Sitaram, A., Demchuk, Andrew M., Lockey, A., Micielli, A., Wadhwa, A., Arabambi, B., Graham, B., Bogiatzi, Chrysi, Doshi, Darshan, Chakraborty, D., Kim, Diana, Vasquez, D, Singh, D, Tse, Dominic, Harrison, E., Smith, E.E., Teleg, E., Klourfeld, E., Klein, G., Sebastian, I.A., Evans, J, Hegedus, J, Kromm, J, Lin, K, Ignacio, K, Ghavami, Kimia, Ismail, M., Moores, M., Panzini, M.A., Boyko, M., Almekhlafi, M.A., Newcommon, Nancy, Maraj, N., Imoukhuede, O., Volny, O., Stys, Peter, Couillard, Phillipe, Ojha, P., Eswaradass, P., Joundi, Raed, Singh, R., Asuncion, R.M., Muir, R.T., Dey, S., Mansoor, S., Wasyliw, S., Nagendra, S., Hu, Sherry, Althubait, S., Chen, S., Bal, S., Van Gaal, Stephen, Peters, Steven, Ray, Sucharita, Chaturvedi, S., Subramaniam, Suresh, Fu, Vivian, Villaluna, K., Maclean, G., King-Azote, P., Ma, C., Plecash, A., Murphy, C., Gorman, J., Wilson, L., Zhou, L., Benevente, O., Teal, P., Yip, S., Mann, S., Dewar, B., Demetroff, M., Shamloul, R., Beardshaw, R., Roberts, S., Blaquiere, D., Stotts, G., Shamy, M., Bereznyakova, O., Fahed, R., Alesefir, W., Lavoie, Suzy, Hache, A., Collard, K, Mackey, A., Gosselin-Lefebvre, S., Verreault, S., Beauchamp, B., Lambourn, L., Khaw, A., Mai, L., Sposato, L., Bres Bullrich, M., Azarpazhooh, R., Fridman, S., Kapoor, A., Southwell, A., Bardi, E., Fatakdawala, I., Kamra, M, Lopes, K., Popel, N., Norouzi, V., Liu, A., Liddy, A.M., Ghoari, B., Hawkes, C., Enriquez, C.A., Gladstone, D.J., Manosalva Alzate, H.A., Khosravani, H., Hopyan, J.J., Sivakumar, K., Son, M., Boulos, M.I., Hamind, M.A., Swartz, R.H., Murphy, R., Reiter, S., Fitzpatrick, T., Bhandari, V., Good, J., Penn, M., Naylor, M., Frost, S., Cayley, A., Akthar, F., Williams, J., Kalman, L., Crellin, L., Wiegner, R., Singh, R.S., Stewart, T., To, W., Singh, S., Pikula, A., Jaigobin, C., Carpani, F., Silver, F., Janssen, H., Schaafsma, J., del Campo, M., Alskaini, M., Rajendram, P., Fairall, P., Granfield, B., Crawford, D., Jabs, J., White, L., Sivakumar, L., Piquette, L., Nguyen, T., Nomani, A., Wagner, A., Alrohimi, A., Butt, A., D'Souza, A., Gajurel, B., Vekhande, C., Kamble, H., Kalashyan, H., Lloret, M., Benguzzi, M., Arsalan, N., Ishaque, N., Ashayeriahmadabad, R., Samiento, R., Hosseini, S., Kazi, S., Das, S., Sugumar, T., Selchen, D., Kostyrko, P., Muccilli, A., Saposnik, A.G., Vandervelde, C., Ratnayake, K., McMillan, S., Katsanos, A., Shoamanesh, A., Sahlas, D.J., Naidoo, V., Todorov, V., Toma, H., Brar, J., Lee, J., Horton, M., Shand, E., Weatherby, S., Jin, A., Durafourt, B., Jalini, S., Gardner, A., Tyson, C., Junk, E., Foster, K., Bolt, K., Sylvain, N., Maley, S., Urroz, L., Peeling, L., Kelly, M., Whelan, R., Cooley, R., Teitelbaum, J., Boutayeb, A., Moore, A., Cole, E., Waxman, L., Ben-Amor, N., Sanchez, R., Khalil, S., Nehme, A., Legault, C., Tampieri, D., Ehrensperger, E., Vieira, L., Cortes, M., Angle, M., Hannouche, M., Badawy, M., Werner, K., Wieszmuellner, S., Langer, A., Gisold, A., Zach, H., Rommer, P., Macher, S., Blechinger, S., Marik, W., Series, W., Baumgartinger, M., Krebs, S., Koski, J., Eirola, S., Ivanoff, T., Erakanto, A., Kupari, L., Sibolt, G., Panula, J., Tomppo, L., Tiainen, M., Ahlstrom, M., Martinez Majander, N., Suomalainen, O., Raty, S., Levi, C., Kerr, E., Allen, J., Kaauwai, L.P., Belevski, L., Russell, M., Ormond, S., Chew, A., Loiselle, A., Royan, A., Hughes, B., Garcia Esperon, C., Pepper, E., Miteff, F., He, J., Lycett, M., Min, M., Murray, N., Pavey, N., Starling de Barros, R., Gangadharan, S., Dunkerton, S., Waller, S., Canento Sanchez, T., Wellings, T., Edmonds, G., Whittaker, K.A., Ewing, M., Lee, P., Singkang, R., McDonald, A., Dos Santos, A., Shin, C., Jackson, D., Tsoleridis, J., Fisicchia, L., Parsons, N., Shenoy, N., Smith, S., Sharobeam, A., Balabanski, A., Park, A., Williams, C., Pavlin-Premri, D., Rodrigues, E., Alemseged, F., Ng, F., Zhao, H., Beharry, J., Ng, J.L., Williamson, J., Wong, J.Z.W., Li, K., Kwan, M.K., Valente, M., Yassi, N., Yogendrakumar, V., McNamara, B., Buchanan, C., McCarthy, C., Thomas, G., Stephens, K., Chung, M., Chung, M.F., Tang, M., Busch, T., Frost, T., Lee, R., Stuart, N., Pachani, N., Menon, A., Borojevic, B., Linton, C.M., Garcia, G., Callaly, E.P., Dewey, H., Liu, J., Chen, J., Wong, J., Nowak, K., To, K., Lizak, N.S., Bhalala, O., Park, P., Tan, P., Martins, R., Cody, R., Forbes, R., Chen, S.K., Ooi, S., Tu, S., Dang, Y.L., Ling, Z., Cranefield, J., Drew, R., Tan, A., Kurunawai, C., Harvey, J., Mahadevan, J.J., Cagi, L., Palanikumar, L., Chia, L.N., Goh, R., El-Masri, S., Urbi, B., Rapier, C., Berrill, H., McEvoy, H., Dunning, R., Kuriakose, S., Chad, T., Sapaen, V., Sabet, A., Shah, D., Yeow, D., Lilley, K., Ward, K., Mozhy Mahizhnan, M., Tan, M., Lynch, C., Coveney, S., Tobin, K., McCabe, J., Marnane, M., Murphy, S., Large, M., Moynihan, B., Boyle, K., Sanjuan, E., Sanchis, M., Boned, S., Pancorbo, O., Sala, V., Garcia, L., Garcia-Tornel, A., Juega, J., Pagola, J., Santana, K., Requena, M., Muchada, M., Olive, M., Lozano, P.J., Rubiera, M., Deck, M., Rodriguez, N., Gomez, B., Reyes Munoz, F.J., Gomez, A.S., Sanz, A.C., Garcia, E.C., Penacoba, G., Ramos, M.E., de Lera Alfonso, M., Feliu, A, Pardo, L., Ramirez, P., Murillo, A., Lopez Dominguez, D., Rodriguez, J., Terceno Izaga, M., Reina, M., Viturro, S.B., Bojaryn, U., Vera Monge, V.A., Silva Blas, Y., R Siew, R., Agustin, S J, Seet, C., Tianming, T., d'Emden, A., Murray, A., Welch, A., Hatherley, K., Day, N., Smith, W., MacRae, E., Mitchell, E.S., Mahmood, A., Elliot, J., Neilson, S., Biswas, V., Brown, C., Lewis, A., Ashton, A., Werring, D., Perry, R., Muhammad, R., Lee, Y.C., Black, A., Robinson, A., Williams, A., Banaras, A., Cahoy, C., Raingold, G., Marinescu, M., Atang, N., Bason, N., Francia, N., Obarey, S., Feerick, S., Joseph, J., Schulz, U., Irons, R., Benjamin, J., Quinn, L., Jhoots, M., Teal, R., Ford, G., Harston, G., Bains, H., Gbinigie, I., Mathieson, P., Sim, C.H., Hayter, E., Kennedy, K., Binnie, L., Priestley, N., Williams, R., Ghatala, R., Stratton, S., Blight, A., Zhang, L., Davies, A., Duffy, H., Roberts, J., Homer, J., Roberts, K., Dodd, K., Cawley, K., Martin, M., Leason, S., Cotgreave, S., Taylor, T., Nallasivan, A., Haider, S., Chakraborty, T., Webster, T., Gil, A., Martin, B., Joseph, B., Cabrera, C., Jose, D., Man, J., Aquino, J., Sebastian, S., Osterdahl, M., Kwan, M., Matthew, M., Ike, N., Bello, P., Wilding, P., Fuentes, R., Shah, R., Mashate, S., Patel, T., Nwanguma, U., Dave, V., Haber, A., Lee, A., O'Sullivan, A., Drumm, B., Dawson, A.C., Matar, T., Roberts, D., Taylor, E., Rounis, E., El-Masry, A., O'Hare, C., Kalladka, D., Jamil, S., Auger, S., Raha, O., Evans, M., Vonberg, F., Kalam, S., Ali Sheikh, A., Jenkins, I.H., George, J., Kwan, J., Blagojevic, J., Saeed, M., Haji-Coll, M., Tsuda, M., Sayed, M., Winterkron, N., Thanbirajah, N., Vittay, O., Karim, R., Smail, R.C., Gauhar, S., Elmamoun, S., Malani, S., Pralhad Kelavkar, S., Hiden, J., Ferdinand, P., Sanyal, R., Varquez, R., Smith, B., Okechukwu, C., Fox, E., Collins, E., Courtney, K., Tauro, S., Patterson, C., McShane, D., Roberts, G., McIImoyle, J., McGuire, K., Fearon, P., Gordon, P., Isaacs, K., Lucas, K., Smith, L., Dews, L., Bates, M., Lawrence, S., Heeley, S., Patel, V., Chin, Y.M., Sims, D., Littleton, E., Khaira, J., Nadar, K., Kieliszkowska, A., Sari, B., Domingos Belo, C., Smith, E., Manolo, E.Y., Aeron-Thomas, J., Doheny, M., Garcia Pardo, M., Recaman, M., Tibajia, M.C., Aissa, M., Mah, Y., Yu, T., Meenakshisundaram, S., Heller, S., Alsukhni, R., Williams, O., Farag, M., Benger, M., Engineer, A., Bayhonan, S., Conway, S., Bhalla, A., Nouvakis, D., Theochari, E., Boyle, F., Teo, J., King-Robson, J., Law, K.Y., Sztriha, L., McGovern, A., Day, D., Mitchell-Douglas, J., Francis, J., Iqbal, A., Punjabivaryani, P., Anonuevo Reyes, J., Anonuevo Reyes, M., Pauls, M., Buch, A., Hedstrom, A., Hutchinson, C., Kirkland, C., Newham, J., Wilkes, G., Fleming, L., Fleck, N., Franca, A., Chwal, B., Oldoni, C., Mantovani, G., Noll, G., Zanella, L., Soma, M., Secchi, T., Borelli, W., Rimoli, B.P., da Cunha Silva, G.H., Machado Galvao Mondin, L.A., Barbosa Cerantola, R., Imthon, A.K., Esaki, A.S., Camilo, M., Vincenzi, O.C., ds Cruz, R.R., Morillos, M.B., Riccioppa Rodrigues, G.G., Santos Ferreira, K., Pazini, A.M., Pena Pereira, M.A., de Albuquerque, A.L.A., Massote Fontanini, C.E., Matinez Rubio, C.F., dos Santos, D.T., Dias, F.A., Alves, F.F.A., Milani, C., Pegorer Santos, B., Winckler, F., De Souza, J.T., Bonome, L.A.M., Cury Silva, V.A., Teodoro, R.S., Modolo, G.P., Ferreira, N.C., Barbosa dos Santos, D.F., dos Santos Moreira, J.C., Cruz Guedes de Morais, A.B., Vieira, J., Mendes, G., de Queiroz, J.P., Coutts, Shelagh B ^*, Ankolekar, Sandeep, Appireddy, Ramana, Arenillas, Juan F, Assis, Zarina, Bailey, Peter, Barber, Philip A, Bazan, Rodrigo, Buck, Brian H, Butcher, Ken S, Camden, Marie-Christine, Campbell, Bruce C V, Casaubon, Leanne K, Catanese, Luciana, Chatterjee, Kausik, Choi, Philip M C, Clarke, Brian, Dowlatshahi, Dar, Ferrari, Julia, Field, Thalia S, Ganesh, Aravind, Ghia, Darshan, Goyal, Mayank, Greisenegger, Stefan, Halse, Omid, Horn, Mackenzie, Hunter, Gary, Imoukhuede, Oje, Kelly, Peter J, Kennedy, James, Kleinig, Timothy J, Krishnan, Kailash, Lima, Fabricio, Mandzia, Jennifer L, Marko, Martha, Martins, Sheila O, Medvedev, George, Menon, Bijoy K, Mishra, Sachin M, Molina, Carlos, Moussaddy, Aimen, Muir, Keith W, Parsons, Mark W, Penn, Andrew M W, Pille, Arthur, Pontes-Neto, Octávio M, Roffe, Christine, Serena, Joaquin, Simister, Robert, Singh, Nishita, Spratt, Neil, Strbian, Daniel, Tham, Carol H, Wiggam, M Ivan, Williams, David J, Willmot, Mark R, Wu, Teddy, Yu, Amy Y X, Zachariah, George, Zafar, Atif, Zerna, Charlotte, Hill, Michael D

Source: In The Lancet 15-21 June 2024 403(10444):2597-2605

Language discordance as a marker of disparities in cerebrovascular risk and stroke outcomes: A multi-center Canadian study

Authors: Muir, Ryan T., Kapoor, Arunima, Cayley, Megan L., Sicard, Michelle N, Lien, Karen, Southwell, Alisia, Dowlatshahi, Dar, Sahlas, Demetrios J., Saposnik, Gustavo, Mandzia, Jennifer, Casaubon, Leanne K., Hassan, Ayman, Perez, Yael, Selchen, Daniel, Murray, Brian J., Lanctot, Krista, Kapral, Moira K., Herrmann, Nathan, Strother, Stephen, Yu, Amy．Y．X, Austin, Peter C., Bronskill, Susan E., Swartz, Richard H.

Source: In Cerebral Circulation - Cognition and Behavior 2023 4

Predicting Cognitive Impairment in Cerebrovascular Disease Using Spoken Discourse Production

Authors: Roberts, Angela, Aveni, Katharine, Basque, Shalane, Orange, Joseph B., McLaughlin, Paula, Ramirez, Joel, Troyer, Angela K., Gutierrez, Stephanie, Chen, Angie, Bartha, Robert, Binns, Malcolm A., Black, Sandra E., Casaubon, Leanne K., Dowlatshahi, Dar, Hassan, Ayman, Kwan, Donna, Levine, Brian, Mandzia, Jennifer, Sahlas, Demetrios J., Scott, Christopher J. M., Strother, Stephen, Sunderland, Kelly M., Symons, Sean, Swartz, Richard

Source: Topics in Language Disorders. Jan-Mar 2021 41(1):73-98.

Peer Reviewed: Y

Page Count: 26

Sponsoring Agency: National Institute on Deafness and Other Communication Disorders (NIDCD)

Descriptors: Prediction, Discourse Analysis, Language Impairments, Dementia, Risk, Prevention, Speech Communication, Neuropsychology, Diagnostic Tests, Evaluation Criteria, Classification, Evaluation Methods

Efficacy and safety of intravenous nerinetide initiated by paramedics in the field for acute cerebral ischaemia within 3 h of symptom onset (FRONTIER): a phase 2, multicentre, randomised, double-blind, placebo-controlled study.

Authors: Christenson, Jim¹, Hill, Michael D², Swartz, Richard H³, Adams, Corey⁴, Benavente, Oscar¹, Casaubon, Leanne K⁵, Cheskes, Sheldon³, Ganesh, Aravind², Garman, Jonathan Dave⁴, Harris, Cameron⁴, Harris, Devin R⁶, Heard, Kathy⁴, Jenneson, Sandra⁶, Kohli, Yatika⁴, Leroux, Michelle⁴, Mayor-Nunez, Diana⁴, Medvedev, George⁷, Mehdiratta, Manu⁸, Morrison, Laurie J³, Ospel, Johanna Maria²

Source: Lancet; Feb2025, Vol. 405 Issue 10478, p571-582, 12p

Combination Antithrombotic Therapy for Reduction of Recurrent Ischemic Stroke in Intracranial Atherosclerotic Disease.

Authors: Perera, Kanjana S., Sharma, Mukul A., Eikelboom, John W., Ng, Kelvin Kuan Huei, Field, Thalia S., Buck, Brian H., Hill, Michael D., Stotts, Grant, Casaubon, Leanne K., Mandzia, Jennifer, Katsanos, Aristeidis H., Yip, Samuel, Shoamanesh, Ashkan, Young, G. Bryan, Appireddy, Ramana, Nayar, Sumiti, Swartz, Rick, Taylor, Amanda, Carrier, Alexandra, Srivastava, Abhilekh

Source: Stroke (00392499); Feb2025, Vol. 56 Issue 2, p380-389, 10p

Endovascular Treatment Versus Best Medical Therapy in Acute Ischemic Stroke Patients with Mild Symptoms

Authors: Nicholson, Patrick, Byun, Jun-Soo, Lu, Hua, Hilditch, Christopher A., Brinjikji, Waleed, Agid, Ronit, Casaubon, Leanne K., Krings, Timo, Schaafsma, Joanna D., Mendes-Pereira, Vitor

Source: In World Neurosurgery December 2020 144:e837-e841

A Feasibility Study Involving Recruitment and Screening for Aphasia in Acute Stroke: Emerging Viability of the English Adaptation of the Language Screening Test (LASTen)

Authors: Flowers, Heather L., Casaubon, Leanne K., Arulvarathan, Charmaine, Cayley, Anne, Darling, Sherry, Girma, Nesanet, Pothier, MCommPath, Louise, Stewart, Tim, Williams, Janice, Silver, Frank L.

Source: In Archives of Rehabilitation Research and Clinical Translation September 2020 2(3)

Recent Trends in Hospitalizations for Cardiovascular Disease, Stroke, and Vascular Cognitive Impairment in Canada

Authors: Botly, Leigh C.P., Lindsay, M. Patrice, Mulvagh, Sharon L., Hill, Michael D., Goia, Cristina, Martin-Rhee, Michelle, Casaubon, Leanne K., Yip, Cindy Y.Y.

Source: In Canadian Journal of Cardiology July 2020 36(7):1081-1090

Secondary Stroke Prevention in People With Schizophrenia.

Authors: Kapral, Moira K., Porter, Joan, Kurdyak, Paul, Yu, Amy Y. X., Matheson, Emilie, Jiming Fang, Casaubon, Leanne K., Kapoor, Eshita, Sheehan, Kathleen A.

Source: Journal of the American Heart Association; 8/6/2024, Vol. 13 Issue 15, p1-8, 8p

Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial.

Authors: Coutts, Shelagh B^1,2,3,4, scoutts@ucalgary.ca, Ankolekar, Sandeep⁵, Appireddy, Ramana⁶, Arenillas, Juan F^7,8, Assis, Zarina^9,10, Bailey, Peter¹¹, Barber, Philip A¹, Bazan, Rodrigo¹², Buck, Brian H¹³, Butcher, Ken S¹⁴, Camden, Marie-Christine¹⁵, Campbell, Bruce C V¹⁶, Casaubon, Leanne K¹⁷, Catanese, Luciana¹⁸, Chatterjee, Kausik¹⁹, Choi, Philip M C^20,21, Clarke, Brian²², Dowlatshahi, Dar^23,24, Ferrari, Julia²⁵, Field, Thalia S²⁶

Source: Lancet; Jun2024, Vol. 403 Issue 10444, p2597-2605, 9p

Men Are at Higher Risk of Screening Positive for Vascular Cognitive Impairment Compared to Women after Stroke and Transient Ischemic Attack.

Authors: Zinman, Julia, Kapoor, Arunima, Si, Kevin, Sujanthan, Sajeevan, Southwell, Alisia, Cayley, Megan L., Sicard, Michelle N., Lien, Karen, Murray, Brian J., Lanctôt, Krista, Herrmann, Nathan, Dowlatshahi, Dar, Sahlas, Demetrios J., Saposnik, Gustavo, Mandzia, Jennifer L., Casaubon, Leanne K., Hassan, Ayman, Perez, Yael, Swartz, Richard H.

Source: Journal of Alzheimer's Disease; 2023, Vol. 94 Issue 1, p89-94, 6p

Subject Terms: TRANSIENT ischemic attack, ISCHEMIC stroke, MEDICAL screening, COGNITION disorders, STROKE, MONTREAL Cognitive Assessment

Characteristics of the Ontario Neurodegenerative Disease Research Initiative cohort.

Authors: Sunderland, Kelly M., Beaton, Derek, Arnott, Stephen R., Kleinstiver, Peter, Kwan, Donna, Lawrence‐Dewar, Jane M., Ramirez, Joel, Tan, Brian, Bartha, Robert, Black, Sandra E., Borrie, Michael, Brien, Donald, Casaubon, Leanne K., Coe, Brian C., Cornish, Benjamin, Dilliott, Allison A., Dowlatshahi, Dar, Finger, Elizabeth, Fischer, Corinne, Frank, Andrew

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Jan2023, Vol. 19 Issue 1, p226-243, 18p

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Contribution of rare variant associations to neurodegenerative disease presentation.

Authors: Dilliott, Allison A., Abdelhady, Abdalla, Sunderland, Kelly M., Farhan, Sali M. K., Abrahao, Agessandro, Binns, Malcolm A., Black, Sandra E., Borrie, Michael, Casaubon, Leanne K., Dowlatshahi, Dar, Finger, Elizabeth, Fischer, Corinne E., Frank, Andrew, Freedman, Morris, Grimes, David, Hassan, Ayman, Jog, Mandar, Kumar, Sanjeev, Kwan, Donna, Lang, Anthony E.

Source: NPJ Genomic Medicine; 9/28/2021, Vol. 6 Issue 1, p1-9, 9p

Discrepancy between post-treatment infarct volume and 90-day outcome in the ESCAPE randomized controlled trial.

Authors: Ganesh, Aravind, Menon, Bijoy K, Assis, Zarina A, Demchuk, Andrew M, Al-Ajlan, Fahad S, Al-Mekhlafi, Mohammed A, Rempel, Jeremy L, Shuaib, Ashfaq, Baxter, Blaise W, Devlin, Thomas, Thornton, John, Williams, David, Poppe, Alexandre Y, Roy, Daniel, Krings, Timo, Casaubon, Leanne K, Kashani, Nima, Hill, Michael D, Goyal, Mayank

Source: International Journal of Stroke; Jul2021, Vol. 16 Issue 5, p593-601, 9p

Subject Terms: ISCHEMIC stroke, FUNCTIONAL assessment, ENDOVASCULAR surgery, BARTHEL Index, AGE differences

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Recommandations canadiennes pour les pratiques optimales de soins de l'AVC, septième édition : l'acide acétylsalicylique pour la prévention d'événements vasculaires. (French)

Authors: Wein, Theodore, Lindsay, M. Patrice, Gladstone, David J., Poppe, Alexandre, Bell, Alan, Casaubon, Leanne K., Foley, Norine, Coutts, Shelagh B., Cox, Jafna, Douketis, James, Field, Thalia, Gioia, Laura, Habert, Jeffrey, Lang, Eddy, Mehta, Shamir R., Papoushek, Christine, Semchuk, William, Sharma, Mikul, Udell, Jacob A., Lawrence, Stephanie

Source: Canadian Medical Association Journal (CMAJ); 10/5/2020, Vol. 192 Issue 40, pE1174-E1184, 11p

Canadian Stroke Best Practice Recommendations, seventh edition: acetylsalicylic acid for prevention of vascular events.

Authors: Wein, Theodore, Lindsay, M. Patrice, Gladstone, David J., Poppe, Alexandre, Bell, Alan, Casaubon, Leanne K., Foley, Norine, Coutts, Shelagh B., Cox, Jafna, Douketis, James, Field, Thalia, Gioia, Laura, Habert, Jeffrey, Lang, Eddy, Mehta, Shamir R., Papoushek, Christine, Semchuk, William, Sharma, Mikul, Udell, Jacob A., Lawrence, Stephanie

Source: Canadian Medical Association Journal (CMAJ); 3/23/2020, Vol. 192 Issue 12, pE302-E311, 10p, 2 Charts

Subject Terms: ASPIRIN, MEDICAL personnel, HEALTH services administration, CEREBROVASCULAR disease, STROKE, TRANSIENT ischemic attack

Derivation and External Validation of a Scoring System for Predicting Fracture Risk After Ischemic Stroke in a Canadian Cohort.

Authors: Smith, Eric E., Fang, Jiming, Alibhai, Shabbir M., Cram, Peter, Cheung, Angela M., Casaubon, Leanne K., Kapoor, Eshita, Austin, Peter C., Kapral, Moira K.

Source: JAMA Neurology; Aug2019, Vol. 76 Issue 8, p925-931, 7p