Zebrafish bioassay-guided isolation of antiseizure compounds from the Cameroonian medicinal plant Cyperus articulatus L

Authors: Brillatz, Théo, Jacmin, Maxime, Queiroz, Emerson Ferreira, Marcourt, Laurence, Slacanin, Ivan, Petit, Charlotte, Carrupt, Pierre-Alain, Bum, Elisabeth Ngo, Herrling, Paul, Crawford, Alexander D., Wolfender, Jean-Luc

Source: In Phytomedicine 15 April 2020 70

HDM-PAMPA to predict gastrointestinal absorption, binding percentage, equilibrium and kinetics constants with human serum albumin and using 2 end-point measurements

Authors: Bujard, Alban, Petit, Charlotte, Carrupt, Pierre-Alain, Rudaz, Serge, Schappler, Julie

Source: In European Journal of Pharmaceutical Sciences 15 January 2017 97:143-150

Human sirtuins: Structures and flexibility

Authors: Sacconnay, Lionel, Carrupt, Pierre-Alain, Nurisso, Alessandra

Source: In Journal of Structural Biology December 2016 196(3):534-542

Limits of rapid log P determination methods for highly lipophilic and flexible compounds

Authors: Martel, Sophie, Begnaud, Frédéric, Schuler, William, Gillerat, Fabrice, Oberhauser, Nils, Nurisso, Alessandra, Carrupt, Pierre-Alain

Source: In Analytica Chimica Acta 7 April 2016 915:90-101

Modification of a PAMPA model to predict passive gastrointestinal absorption and plasma protein binding

Authors: Bujard, Alban, Voirol, Hervé, Carrupt, Pierre-Alain, Schappler, Julie

Source: In European Journal of Pharmaceutical Sciences 18 September 2015 77:273-278

How the flexibility of human histone deacetylases influences ligand binding: an overview

Authors: Deschamps, Nathalie, Simões-Pires, Claudia Avello, Carrupt, Pierre-Alain, Nurisso, Alessandra

Source: In Drug Discovery Today June 2015 20(6):736-742

Inhibition screening method of microsomal UGTs using the cocktail approach

Authors: Gradinaru, Julieta, Romand, Stéphanie, Geiser, Laurent, Carrupt, Pierre-Alain, Spaggiari, Dany, Rudaz, Serge

Source: In European Journal of Pharmaceutical Sciences 25 April 2015 71:35-45

Passive Intestinal Absorption of Representative Plant Secondary Metabolites: A Physicochemical Study

Authors: Petit, Charlotte, Ceccarelli, Martina, Cretton, Sylvian, Houriet, Joëlle, Skalicka-Woźniak, Krystyna, Christen, Philippe, Carrupt, Pierre-Alain, Goracci, Laura, Wolfender, Jean-Luc

Source: Planta medica. 83(8):718-726

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179836054.0x000001&indx=1&recIds=ETOCvdc_100179836054.0x000001

Retention time prediction for dereplication of natural products (CxHyOz) in LC–MS metabolite profiling

Authors: Eugster, Philippe J., Boccard, Julien, Debrus, Benjamin, Bréant, Lise, Wolfender, Jean-Luc, Martel, Sophie, Carrupt, Pierre-Alain

Source: In Phytochemistry December 2014 108:196-207

Predicting both passive intestinal absorption and the dissociation constant toward albumin using the PAMPA technique

Authors: Bujard, Alban, Sol, Marine, Carrupt, Pierre-Alain, Martel, Sophie

Source: In European Journal of Pharmaceutical Sciences 15 October 2014 63:36-44

cIEF for rapid pKa determination of small molecules: A proof of concept

Authors: Romand, Stéphanie, Schappler, Julie, Veuthey, Jean-Luc, Carrupt, Pierre-Alain, Martel, Sophie

Source: In European Journal of Pharmaceutical Sciences 15 October 2014 63:14-21

Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux

Authors: Lorendeau, Doriane, Dury, Lauriane, Genoux-Bastide, Estelle, Lecerf-Schmidt, Florine, Simões-Pires, Claudia, Carrupt, Pierre-Alain, Terreux, Raphaël, Magnard, Sandrine, Di Pietro, Attilio, Boumendjel, Ahcène, Baubichon-Cortay, Hélène

Source: In Biochemical Pharmacology 1 August 2014 90(3):235-245

Prediction of the Passive Intestinal Absorption of Medicinal Plant Extract Constituents with the Parallel Artificial Membrane Permeability Assay (PAMPA)

Authors: Petit, Charlotte, Bujard, Alban, Skalicka-Woźniak, Krystyna, Cretton, Sylvian, Houriet, Joëlle, Christen, Philippe, Carrupt, Pierre-Alain, Wolfender, Jean-Luc

Source: Planta medica. 82(5):424-431

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176255498.0x000001&indx=1&recIds=ETOCvdc_100176255498.0x000001

Normal phase HPLC-based activity profiling of non-polar crude plant extracts – acetylcholinesterase inhibiting guttiferones from Montrouziera cauliflora as a case study

Authors: Landreau, Anne, Bertrand, Samuel, Simoes-Pires, Claudia, Marcourt, Laurence, Taï, Dang Bach, Litaudon, Marc, Guilet, David, Richomme, Pascal, Carrupt, Pierre-Alain, Wolfender, Jean-Luc

Source: Natural product research. 30(24):2754-2759

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100036888613.0x000001&indx=1&recIds=ETOCvdc_100036888613.0x000001

Molecular dynamics of zinc-finger ubiquitin binding domains: a comparative study of histone deacetylase 6 and ubiquitin-specific protease 5

Authors: dos Santos Passos, Carolina, Simões-Pires, Claudia A., Carrupt, Pierre-Alain, Nurisso, Alessandra

Source: Journal of biomolecular structure & dynamics. 34(12):2581-2598

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100036328733.0x000001&indx=1&recIds=ETOCvdc_100036328733.0x000001

Global analytical strategy to measure drug–plasma protein interactions: from high-throughput to in-depth analysis

Authors: Vuignier, Karine, Veuthey, Jean-Luc, Carrupt, Pierre-Alain, Schappler, Julie

Source: In Drug Discovery Today November 2013 18(21-22):1030-1034

New high throughput screening method for drug release measurements

Authors: Pelczarska, Aleksandra, Delie, Florence, Domańska, Urszula, Carrupt, Pierre-Alain, Martel, Sophie

Source: In European Journal of Pharmaceutics and Biopharmaceutics September 2013 85(1):151-157

Indole alkaloids of Psychotria as multifunctional cholinesterases and monoamine oxidases inhibitors

Authors: Passos, Carolina S., Simões-Pires, Claudia A., Nurisso, Alessandra, Soldi, Tatiane C., Kato, Lucilia, de Oliveira, Cecilia M.A., de Faria, Emiret O., Marcourt, Laurence, Gottfried, Carmem, Carrupt, Pierre-Alain, Henriques, Amélia T.

Source: In Phytochemistry February 2013 86:8-20

Large, chemically diverse dataset of log P measurements for benchmarking studies

Authors: Martel, Sophie, Gillerat, Fabrice, Carosati, Emanuele, Maiarelli, Daniele, Tetko, Igor V., Mannhold, Raimund, Carrupt, Pierre-Alain

Source: In European Journal of Pharmaceutical Sciences 23 January 2013 48(1-2):21-29

Alkaloids from Psychotria Target Sirtuins: In Silico and In Vitro Interaction Studies

Authors: Sacconnay, Lionel, Ryckewaert, Lucie, dos Santos Passos, Carolina, Guerra, Maria, Kato, Lucilia, Alves de Oliveira, Cecilia, Henriques, Amélia, Carrupt, Pierre-Alain, Simões-Pires, Claudia, Nurisso, Alessandra

Source: Planta medica. 81(6):517-524

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163920108.0x000001&indx=1&recIds=ETOCvdc_100163920108.0x000001