X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

Authors: Peixiang Zhang, Joseph J. Munier, Carrie B. Wiese, Laurent Vergnes, Jenny C. Link, Fahim Abbasi, Emilio Ronquillo, Katherine Scheker, Antonio Muñoz, Yu-Lin Kuang, Elizabeth Theusch, Meng Lu, Gabriela Sanchez, Akinyemi Oni-Orisan, Carlos Iribarren, Michael J. McPhaul, Daniel K. Nomura, Joshua W. Knowles, Ronald M. Krauss, Marisa W. Medina, Karen Reue

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/332ede39ee3b4894add02807a1a4ed96

Interplay between lifestyle factors and polygenic risk for incident coronary heart disease in a large multiethnic cohort

Authors: Carlos Iribarren, Meng Lu, Martha Gulati, Nathan D. Wong, Roberto Elosua, Jamal S. Rana

Source: International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 23, Iss , Pp 200350- (2024)

Subject Terms: Polygenic risk score, Coronary heart disease risk, Lifestyle factors, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772487524001156; https://doaj.org/toc/2772-4875

Access URL: https://doaj.org/article/b072970a0d904bcda9d4a7b94058b862

Polygenic risk and incident coronary heart disease in a large multiethnic cohort

Authors: Carlos Iribarren, Meng Lu, Roberto Elosua, Martha Gulati, Nathan D. Wong, Roger S. Blumenthal, Steven Nissen, Jamal S. Rana

Source: American Journal of Preventive Cardiology, Vol 18, Iss , Pp 100661- (2024)

Subject Terms: Polygenic risk score, Coronary heart disease, Clinical utility, Primary prevention, Diseases of the circulatory (Cardiovascular) system, RC666-701, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666667724000291; https://doaj.org/toc/2666-6677

Access URL: https://doaj.org/article/4d6efadf5cc94724a96e6b32a43ce67f

Genetic insights into resting heart rate and its role in cardiovascular disease

Authors: Yordi J. van de Vegte, Ruben N. Eppinga, M. Yldau van der Ende, Yanick P. Hagemeijer, Yuvaraj Mahendran, Elias Salfati, Albert V. Smith, Vanessa Y. Tan, Dan E. Arking, Ioanna Ntalla, Emil V. Appel, Claudia Schurmann, Jennifer A. Brody, Rico Rueedi, Ozren Polasek, Gardar Sveinbjornsson, Cecile Lecoeur, Claes Ladenvall, Jing Hua Zhao, Aaron Isaacs, Lihua Wang, Jian’an Luan, Shih-Jen Hwang, Nina Mononen, Kirsi Auro, Anne U. Jackson, Lawrence F. Bielak, Linyao Zeng, Nabi Shah, Maria Nethander, Archie Campbell, Tuomo Rankinen, Sonali Pechlivanis, Lu Qi, Wei Zhao, Federica Rizzi, Toshiko Tanaka, Antonietta Robino, Massimiliano Cocca, Leslie Lange, Martina Müller-Nurasyid, Carolina Roselli, Weihua Zhang, Marcus E. Kleber, Xiuqing Guo, Henry J. Lin, Francesca Pavani, Tessel E. Galesloot, Raymond Noordam, Yuri Milaneschi, Katharina E. Schraut, Marcel den Hoed, Frauke Degenhardt, Stella Trompet, Marten E. van den Berg, Giorgio Pistis, Yih-Chung Tham, Stefan Weiss, Xueling S. Sim, Hengtong L. Li, Peter J. van der Most, Ilja M. Nolte, Leo-Pekka Lyytikäinen, M. Abdullah Said, Daniel R. Witte, Carlos Iribarren, Lenore Launer, Susan M. Ring, Paul S. de Vries, Peter Sever, Allan Linneberg, Erwin P. Bottinger, Sandosh Padmanabhan, Bruce M. Psaty, Nona Sotoodehnia, Ivana Kolcic, The DCCT/EDIC Research Group, David O. Arnar, Daniel F. Gudbjartsson, Hilma Holm, Beverley Balkau, Claudia T. Silva, Christopher H. Newton-Cheh, Kjell Nikus, Perttu Salo, Karen L. Mohlke, Patricia A. Peyser, Heribert Schunkert, Mattias Lorentzon, Jari Lahti, Dabeeru C. Rao, Marilyn C. Cornelis, Jessica D. Faul, Jennifer A. Smith, Katarzyna Stolarz-Skrzypek, Stefania Bandinelli, Maria Pina Concas, Gianfranco Sinagra, Thomas Meitinger, Melanie Waldenberger, Moritz F. Sinner, Konstantin Strauch, Graciela E. Delgado, Kent D. Taylor, Jie Yao, Luisa Foco, Olle Melander, Jacqueline de Graaf, Renée de Mutsert, Eco J. C. de Geus, Åsa Johansson, Peter K. Joshi, Lars Lind, Andre Franke, Peter W. Macfarlane, Kirill V. Tarasov, Nicholas Tan, Stephan B. Felix, E-Shyong Tai, Debra Q. Quek, Harold Snieder, Johan Ormel, Martin Ingelsson, Cecilia Lindgren, Andrew P. Morris, Olli T. Raitakari, Torben Hansen, Themistocles Assimes, Vilmundur Gudnason, Nicholas J. Timpson, Alanna C. Morrison, Patricia B. Munroe, David P. Strachan, Niels Grarup, Ruth J. F. Loos, Susan R. Heckbert, Peter Vollenweider, Caroline Hayward, Kari Stefansson, Philippe Froguel, Leif Groop, Nicholas J. Wareham, Cornelia M. van Duijn, Mary F. Feitosa, Christopher J. O’Donnell, Mika Kähönen, Markus Perola, Michael Boehnke, Sharon L. R. Kardia, Jeanette Erdmann, Colin N. A. Palmer, Claes Ohlsson, David J. Porteous, Johan G. Eriksson, Claude Bouchard, Susanne Moebus, Peter Kraft, David R. Weir, Daniele Cusi, Luigi Ferrucci, Sheila Ulivi, Giorgia Girotto, Adolfo Correa, Stefan Kääb, Annette Peters, John C. Chambers, Jaspal S. Kooner, Winfried März, Jerome I. Rotter, Andrew A. Hicks, J. Gustav Smith, Lambertus A. L. M. Kiemeney, Dennis O. Mook-Kanamori, Brenda W. J. H. Penninx, Ulf Gyllensten, James F. Wilson, Stephen Burgess, Johan Sundström, Wolfgang Lieb, J. Wouter Jukema, Mark Eijgelsheim, Edward L. M. Lakatta, Ching-Yu Cheng, Marcus Dörr, Tien-Yin Wong, Charumathi Sabanayagam, Albertine J. Oldehinkel, Harriette Riese, Terho Lehtimäki, Niek Verweij, Pim van der Harst

Source: Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3c84ab4f05154b7e8a3a7baac64d83e1

Asthma exacerbations and eosinophilia in the UK Biobank: a genome-wide association study

Authors: Ahmed Edris, Kirsten Voorhies, Sharon M. Lutz, Carlos Iribarren, Ian Hall, Ann Chen Wu, Martin Tobin, Katherine Fawcett, Lies Lahousse

Source: ERJ Open Research, Vol 10, Iss 1 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://openres.ersjournals.com/content/10/1/00566-2023.full; https://doaj.org/toc/2312-0541

Access URL: https://doaj.org/article/e58f8eefa83b4c4393c364d85f85daa2

Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort

Authors: Tanushree Haldar, Akinyemi Oni-Orisan, Thomas J. Hoffmann, Catherine Schaefer, Carlos Iribarren, Ronald M. Krauss, Marisa W. Medina, Neil Risch

Source: Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-11 (2022)

Subject Terms: Statin, Fasting glucose, Cohort study, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/4620badd8b7f483582fef8c858bcb07f

Extracting patient-level data from the electronic health record: Expanding opportunities for health system research.

Authors: Erica Farrand, Harold R Collard, Michael Guarnieri, George Minowada, Lawrence Block, Mei Lee, Carlos Iribarren

Source: PLoS ONE, Vol 18, Iss 3, p e0280342 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c288e88ec196412c8925103900d8de64

High-sensitivity troponin I is associated with cardiovascular outcomes but not with breast arterial calcification among postmenopausal women

Authors: Carlos Iribarren, Malini Chandra, Catherine Lee, Gabriela Sanchez, Danny L. Sam, Farima Faith Azamian, Hyo-Min Cho, Huanjun Ding, Nathan D. Wong, Sabee Molloi

Source: International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 15, Iss , Pp 200157- (2022)

Subject Terms: High-sensitivity troponin I, Breast arterial calcification, Cardiovascular disease, Women's health, Cohort study, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772487522000332; https://doaj.org/toc/2772-4875

Access URL: https://doaj.org/article/14c344e58e254fb99600e80b33ed8d23

Torsade de pointes: A nested case–control study in an integrated healthcare delivery system

Authors: Neha Mantri, Meng Lu, Jonathan G. Zaroff, Neil Risch, Thomas Hoffmann, Akinyemi Oni‐Orisan, Catherine Lee, Carlos Iribarren

Source: Annals of Noninvasive Electrocardiology, Vol 27, Iss 1, Pp n/a-n/a (2022)

Subject Terms: case, control study, long QT syndrome, risk factors, torsade de pointes, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1082-720X; https://doaj.org/toc/1542-474X

Access URL: https://doaj.org/article/1c61a7d68c664623a160ec22860fc057

QT Interval Dynamics and Cardiovascular Outcomes: A Cohort Study in an Integrated Health Care Delivery System

Authors: Neha Mantri, Meng Lu, Jonathan G. Zaroff, Neil Risch, Thomas Hoffmann, Akinyemi Oni‐Orisan, Catherine Lee, Eric Jorgenson, Carlos Iribarren

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 19 (2021)

Subject Terms: epidemiology, long QT, QT interval, short QT syndrome, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/195f96e6bcba45129d22ca75788a1a4f

Occupation versus environmental factors in hypersensitivity pneumonitis: population attributable fraction

Authors: Hayley Barnes, Anna-Carin Olin, Kjell Torén, Charles McSharry, Iona Donnelly, Mona Lärstad, Carlos Iribarren, Patricia Quinlan, Paul D. Blanc

Source: ERJ Open Research, Vol 6, Iss 4 (2020)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://openres.ersjournals.com/content/6/4/00374-2020.full; https://doaj.org/toc/2312-0541

Access URL: https://doaj.org/article/fba53af67a1943149442222929bac43e

Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry

Authors: Carlos Iribarren, Meng Lu, Eric Jorgenson, Manuel Martínez, Carla Lluis-Ganella, Isaac Subirana, Eduardo Salas, Roberto Elosua

Source: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/16ad16b4734e46d19e221465c6c10b06

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation

Authors: Yu-Lin Kuang, Antonio Munoz, Gilbert Nalula, Katherine E. Santostefano, Valentina Sanghez, Gabriela Sanchez, Naohiro Terada, Aras N. Mattis, Michelina Iacovino, Carlos Iribarren, Ronald M. Krauss, Marisa W. Medina

Source: Stem Cell Research, Vol 37, Iss , Pp - (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506119300649; https://doaj.org/toc/1873-5061

Access URL: https://doaj.org/article/7c15eabdc9724fd391a8a8b8139bc304

Kidney function, proteinuria and breast arterial calcification in women without clinical cardiovascular disease: The MINERVA study.

Authors: Rishi V Parikh, Carlos Iribarren, Catherine Lee, Tory Levine-Hall, Thida C Tan, Gabriela Sanchez, Huanjun Ding, Fatemeh Azamian Bidgoli, Sabee Molloi, Alan S Go

Source: PLoS ONE, Vol 14, Iss 1, p e0210973 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fc804f235f7e41789396036d1c07e6f2

Cohort Study of ECG Left Ventricular Hypertrophy Trajectories: Ethnic Disparities, Associations With Cardiovascular Outcomes, and Clinical Utility

Authors: Carlos Iribarren, Alfred D. Round, Meng Lu, Peter M. Okin, Edward J. McNulty

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)

Subject Terms: cohort study, Cornell voltage product, electrocardiography, left ventricular hypertrophy, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/8f47c84adb3540c3b53deeb32c6ad947

The impact of SHS exposure on health status and exacerbations among patients with COPD

Authors: Mark D Eisner, Carlos Iribarren, Edward H Yelin, Stephen Sidney, et al.

Source: International Journal of COPD, Vol 2009, Iss default, Pp 169-176 (2009)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://www.dovepress.com/the-impact-of-shs-exposure-on-health-status-and-exacerbations-among-pa-a3094; https://doaj.org/toc/1176-9106; https://doaj.org/toc/1178-2005

Access URL: https://doaj.org/article/4c132723b3614d1aa835f80a3953d357

Fifteen-Year Prospective Analysis of Television Viewing and Adiposity in African American and Caucasian Men and Women

Authors: Chung-Yu Chen, Mark A. Pereira, Kevin H. Kim, Darin Erickson, David R. Jacobs, Janice C. Zgibor, Tammy Chung, Stephen Sidney, Carlos Iribarren, Anthony Fabio

Source: SAGE Open, Vol 5 (2015)

Subject Terms: History of scholarship and learning. The humanities, AZ20-999, Social Sciences

File Description: electronic resource

Relation: https://doaj.org/toc/2158-2440

Access URL: https://doaj.org/article/3e62acf919d14e0588efe3441d0eb572

Hostility Modifies the Association between TV Viewing and Cardiometabolic Risk

Authors: Anthony Fabio, Chung-Yu Chen, Kevin H. Kim, Darin Erickson, David R. Jacobs, Janice C. Zgibor, Tammy Chung, Karen A. Matthews, Steven Sidney, Carlos Iribarren, Mark A. Pereira

Source: Journal of Obesity, Vol 2014 (2014)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://doaj.org/toc/2090-0708; https://doaj.org/toc/2090-0716

Access URL: https://doaj.org/article/33249196e74148adb523fee7d7893626

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.

Authors: Joshua C Randall, Thomas W Winkler, Zoltán Kutalik, Sonja I Berndt, Anne U Jackson, Keri L Monda, Tuomas O Kilpeläinen, Tõnu Esko, Reedik Mägi, Shengxu Li, Tsegaselassie Workalemahu, Mary F Feitosa, Damien C Croteau-Chonka, Felix R Day, Tove Fall, Teresa Ferreira, Stefan Gustafsson, Adam E Locke, Iain Mathieson, Andre Scherag, Sailaja Vedantam, Andrew R Wood, Liming Liang, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Emmanouil T Dermitzakis, Antigone S Dimas, Fredrik Karpe, Josine L Min, George Nicholson, Deborah J Clegg, Thomas Person, Jon P Krohn, Sabrina Bauer, Christa Buechler, Kristina Eisinger, DIAGRAM Consortium, Amélie Bonnefond, Philippe Froguel, MAGIC Investigators, Jouke-Jan Hottenga, Inga Prokopenko, Lindsay L Waite, Tamara B Harris, Albert Vernon Smith, Alan R Shuldiner, Wendy L McArdle, Mark J Caulfield, Patricia B Munroe, Henrik Grönberg, Yii-Der Ida Chen, Guo Li, Jacques S Beckmann, Toby Johnson, Unnur Thorsteinsdottir, Maris Teder-Laving, Kay-Tee Khaw, Nicholas J Wareham, Jing Hua Zhao, Najaf Amin, Ben A Oostra, Aldi T Kraja, Michael A Province, L Adrienne Cupples, Nancy L Heard-Costa, Jaakko Kaprio, Samuli Ripatti, Ida Surakka, Francis S Collins, Jouko Saramies, Jaakko Tuomilehto, Antti Jula, Veikko Salomaa, Jeanette Erdmann, Christian Hengstenberg, Christina Loley, Heribert Schunkert, Claudia Lamina, H Erich Wichmann, Eva Albrecht, Christian Gieger, Andrew A Hicks, Asa Johansson, Peter P Pramstaller, Sekar Kathiresan, Elizabeth K Speliotes, Brenda Penninx, Anna-Liisa Hartikainen, Marjo-Riitta Jarvelin, Ulf Gyllensten, Dorret I Boomsma, Harry Campbell, James F Wilson, Stephen J Chanock, Martin Farrall, Anuj Goel, Carolina Medina-Gomez, Fernando Rivadeneira, Karol Estrada, André G Uitterlinden, Albert Hofman, M Carola Zillikens, Martin den Heijer, Lambertus A Kiemeney, Andrea Maschio, Per Hall, Jonathan Tyrer, Alexander Teumer, Henry Völzke, Peter Kovacs, Anke Tönjes, Massimo Mangino, Tim D Spector, Caroline Hayward, Igor Rudan, Alistair S Hall, Nilesh J Samani, Antony Paul Attwood, Jennifer G Sambrook, Joseph Hung, Lyle J Palmer, Marja-Liisa Lokki, Juha Sinisalo, Gabrielle Boucher, Heikki Huikuri, Mattias Lorentzon, Claes Ohlsson, Niina Eklund, Johan G Eriksson, Cristina Barlassina, Carlo Rivolta, Ilja M Nolte, Harold Snieder, Melanie M Van der Klauw, Jana V Van Vliet-Ostaptchouk, Pablo V Gejman, Jianxin Shi, Kevin B Jacobs, Zhaoming Wang, Stephan J L Bakker, Irene Mateo Leach, Gerjan Navis, Pim van der Harst, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Jian Yang, Daniel I Chasman, Paul M Ridker, Lynda M Rose, Terho Lehtimäki, Olli Raitakari, Devin Absher, Carlos Iribarren, Hanneke Basart, Kees G Hovingh, Elina Hyppönen, Chris Power, Denise Anderson, John P Beilby, Jennie Hui, Jennifer Jolley, Hendrik Sager, Stefan R Bornstein, Peter E H Schwarz, Kati Kristiansson, Markus Perola, Jaana Lindström, Amy J Swift, Matti Uusitupa, Mustafa Atalay, Timo A Lakka, Rainer Rauramaa, Jennifer L Bolton, Gerry Fowkes, Ross M Fraser, Jackie F Price, Krista Fischer, Kaarel Krjutå Kov, Andres Metspalu, Evelin Mihailov, Claudia Langenberg, Jian'an Luan, Ken K Ong, Peter S Chines, Sirkka M Keinanen-Kiukaanniemi, Timo E Saaristo, Sarah Edkins, Paul W Franks, Göran Hallmans, Dmitry Shungin, Andrew David Morris, Colin N A Palmer, Raimund Erbel, Susanne Moebus, Markus M Nöthen, Sonali Pechlivanis, Kristian Hveem, Narisu Narisu, Anders Hamsten, Steve E Humphries, Rona J Strawbridge, Elena Tremoli, Harald Grallert, Barbara Thorand, Thomas Illig, Wolfgang Koenig, Martina Müller-Nurasyid, Annette Peters, Bernhard O Boehm, Marcus E Kleber, Winfried März, Bernhard R Winkelmann, Johanna Kuusisto, Markku Laakso, Dominique Arveiler, Giancarlo Cesana, Kari Kuulasmaa, Jarmo Virtamo, John W G Yarnell, Diana Kuh, Andrew Wong, Lars Lind, Ulf de Faire, Bruna Gigante, Patrik K E Magnusson, Nancy L Pedersen, George Dedoussis, Maria Dimitriou, Genovefa Kolovou, Stavroula Kanoni, Kathleen Stirrups, Lori L Bonnycastle, Inger Njølstad, Tom Wilsgaard, Andrea Ganna, Emil Rehnberg, Aroon Hingorani, Mika Kivimaki, Meena Kumari, Themistocles L Assimes, Inês Barroso, Michael Boehnke, Ingrid B Borecki, Panos Deloukas, Caroline S Fox, Timothy Frayling, Leif C Groop, Talin Haritunians, David Hunter, Erik Ingelsson, Robert Kaplan, Karen L Mohlke, Jeffrey R O'Connell, David Schlessinger, David P Strachan, Kari Stefansson, Cornelia M van Duijn, Gonçalo R Abecasis, Mark I McCarthy, Joel N Hirschhorn, Lu Qi, Ruth J F Loos, Cecilia M Lindgren, Kari E North, Iris M Heid

Source: PLoS Genetics, Vol 9, Iss 6, p e1003500 (2013)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3674993?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/2a376c2631d74ba1a23a7f38df816835

Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Coronary Heart Disease

Authors: Jean Dallongeville, Carlos Iribarren, Jean Ferrières, Liisa Lyon, Alun Evans, Alan S. Go, Dominique Arveiler, Stephen P. Fortmann, Pierre Ducimetière, Mark A. Hlatky, Philippe Amouyel, Audrey Southwick, Thomas Quertermous, Aline Meirhaeghe

Source: PPAR Research, Vol 2009 (2009)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1687-4757; https://doaj.org/toc/1687-4765

Access URL: https://doaj.org/article/0810e8153aa04b1a8c0f8528843e6147