Apolipoprotein A-IV is induced by high-fat diets and mediates positive effects on glucose and lipid metabolism

Authors: Lundsgaard, Anne-Marie ^{1, 2}, Del Giudice, Rita ^{3, 4}, Kanta, Josephine M. ¹, Larance, Mark ⁵, Armour, Sarah L. ⁶, London, Amalie ^{1, 7}, Richter, Michael M. ^{1, 7, 8}, Andersen, Nicoline R. ^{1, 9}, Nicolaisen, Trine S. ¹, Carl, Christian S. ^{1, 9}, Sjøberg, Kim A. ¹, Bojsen-Møller, Kirstine Nyvold ^{7, 10}, Knudsen, Jakob G. ⁶, Lagerstedt, Jens O. ^{3, 11}, Fritzen, Andreas M. ^{1, 9}, Kiens, Bente ^{1, ⁎}

Source: In Molecular Metabolism May 2025 95

Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function

Authors: Blazev, Ronnie, Carl, Christian S., Ng, Yaan-Kit, Molendijk, Jeffrey, Voldstedlund, Christian T., Zhao, Yuanyuan, Xiao, Di, Kueh, Andrew J., Miotto, Paula M., Haynes, Vanessa R., Hardee, Justin P., Chung, Jin D., McNamara, James W., Qian, Hongwei, Gregorevic, Paul, Oakhill, Jonathan S., Herold, Marco J., Jensen, Thomas E., Lisowski, Leszek, Lynch, Gordon S., Dodd, Garron T., Watt, Matthew J., Yang, Pengyi, Kiens, Bente, Richter, Erik A., Parker, Benjamin L.

Source: In Cell Metabolism 4 October 2022 34(10):1561-1577

Pantothenate kinase 4 controls skeletal muscle substrate metabolism.

Authors: Miranda-Cervantes, Adriana, Fritzen, Andreas M., Raun, Steffen H., Hodek, Ondřej, Møller, Lisbeth L. V., Johann, Kornelia, Deisen, Luisa, Gregorevic, Paul, Gudiksen, Anders, Artati, Anna, Adamski, Jerzy, Andersen, Nicoline R., Sigvardsen, Casper M., Carl, Christian S., Voldstedlund, Christian T., Kjøbsted, Rasmus, Hauck, Stefanie M., Schjerling, Peter, Jensen, Thomas E., Cebrian-Serrano, Alberto

Source: Nature Communications; 1/2/2025, Vol. 16, p1-15, 15p

Subject Terms: FATTY acid oxidation, MUSCLE metabolism, GLUCOSE intolerance, GLUCOSE metabolism, LIPID metabolism, ACETYLCOENZYME A

pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise

Authors: Reddy, Anita, Bozi, Luiz H.M., Yaghi, Omar K., Mills, Evanna L., Xiao, Haopeng, Nicholson, Hilary E., Paschini, Margherita, Paulo, Joao A., Garrity, Ryan, Laznik-Bogoslavski, Dina, Ferreira, Julio C.B., Carl, Christian S., Sjøberg, Kim A., Wojtaszewski, Jørgen F.P., Jeppesen, Jacob F., Kiens, Bente, Gygi, Steven P., Richter, Erik A., Mathis, Diane, Chouchani, Edward T.

Source: In Cell 1 October 2020 183(1):62-75

ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2

Authors: Fritzen, Andreas Mæchel, Domingo-Espín, Joan, Lundsgaard, Anne-Marie, Kleinert, Maximilian, Israelsen, Ida, Carl, Christian S., Nicolaisen, Trine S., Kjøbsted, Rasmus, Jeppesen, Jacob F., Wojtaszewski, Jørgen F.P., Lagerstedt, Jens O., Kiens, Bente

Source: In Molecular Metabolism May 2020 35

Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation

Authors: Lundsgaard, Anne-Marie ^*, Fritzen, Andreas M. ^*, Nicolaisen, Trine S. ^*, Carl, Christian S. ^*, Sjøberg, Kim A. ^*, Raun, Steffen H. ^*, Klein, Anders B. ^†, Sanchez-Quant, Eva ^§, Langer, Jakob ^§, Ørskov, Cathrine ^**, Clemmensen, Christoffer ^†, Tschöp, Matthias H. ^{§, ††, §§}, Richter, Erik A. ^*, Kiens, Bente ^*, Kleinert, Maximilian ^{*, §}

Source: In Journal of Lipid Research January 2020 61(1):10-19

Thyroid hormone receptor α in skeletal muscle is essential for T3‐mediated increase in energy expenditure

Authors: Nicolaisen, Trine S., Klein, Anders B., Dmytriyeva, Oksana, Lund, Jens, Ingerslev, Lars R., Fritzen, Andreas M., Carl, Christian S., Lundsgaard, Anne‐Marie, Frost, Mikkel, Ma, Tao, Schjerling, Peter, Gerhart‐Hines, Zachary, Flamant, Frederic, Gauthier, Karine, Larsen, Steen, Richter, Erik A., Kiens, Bente, Clemmensen, Christoffer

Source: FASEB journal. 34(11):15480-15491

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115881228.0x000001&indx=1&recIds=ETOCvdc_100115881228.0x000001

Greater molecular potential for glucose metabolism in adipose tissue and skeletal muscle of women compared with men.

Authors: Nicolaisen, Trine S., Sjøberg, Kim A., Carl, Christian S., Richter, Erik A., Kiens, Bente, Fritzen, Andreas M., Lundsgaard, Anne‐Marie

Source: FASEB Journal; Aug2024, Vol. 38 Issue 15, p1-14, 14p

Pharmacological Activation of PDC Flux Reverses Lipid-Induced Inhibition of Insulin Action in Muscle During Recovery From Exercise.

Authors: Carl, Christian S.¹ (AUTHOR), Jensen, Marie M.² (AUTHOR), Sjøberg, Kim A.¹ (AUTHOR), Constantin-Teodosiu, Dumitru³ (AUTHOR), Hill, Ian R.³ (AUTHOR), Kjøbsted, Rasmus¹ (AUTHOR), Greenhaff, Paul L.³ (AUTHOR), Wojtaszewski, Jørgen F.P.¹ (AUTHOR), Richter, Erik A.¹ (AUTHOR), Fritzen, Andreas M.^1,4 (AUTHOR), Kiens, Bente¹ (AUTHOR) bkiens@nexs.ku.dk

Source: Diabetes. Jul2024, Vol. 73 Issue 7, p1072-1083. 12p.

Subject Terms: *COOLDOWN, *PYRUVATE dehydrogenase complex, *INSULIN sensitivity, *TYPE 2 diabetes, *LEG muscles, *LEG exercises

Characterization of the skeletal muscle arginine methylome in health and disease reveals remodeling in amyotrophic lateral sclerosis.

Authors: Wong, Julian P. H., Blazev, Ronnie, Ng, Yaan‐Kit, Goodman, Craig A., Montgomery, Magdalene K., Watt, Kevin I., Carl, Christian S., Watt, Matthew J., Voldstedlund, Christian T., Richter, Erik A., Crouch, Peter J., Steyn, Frederik J., Ngo, Shyuan T., Parker, Benjamin L.

Source: FASEB Journal; 5/31/2024, Vol. 38 Issue 10, p1-19, 19p

An exercise-inducible metabolite that suppresses feeding and obesity.

Authors: Li, Veronica L., He, Yang, Contrepois, Kévin, Liu, Hailan, Kim, Joon T., Wiggenhorn, Amanda L., Tanzo, Julia T., Tung, Alan Sheng-Hwa, Lyu, Xuchao, Zushin, Peter-James H., Jansen, Robert S., Michael, Basil, Loh, Kang Yong, Yang, Andrew C., Carl, Christian S., Voldstedlund, Christian T., Wei, Wei, Terrell, Stephanie M., Moeller, Benjamin C., Arthur, Rick M.

Source: Nature; 6/232022, Vol. 606 Issue 7915, p785-790, 6p

Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle.

Authors: Knudsen, Jonas R., Persson, Kaspar W., Meister, Jaroslawna, Carl, Christian S., Raun, Steffen H., Andersen, Nicoline R., Sylow, Lykke, Kiens, Bente, Jensen, Thomas E., Richter, Erik A., Kleinert, Maximilian

Source: American Journal of Physiology: Endocrinology & Metabolism; Jan2022, Vol. 322 Issue 1, pE63-E73, 11p

Subject Terms: SKELETAL muscle, ADRENERGIC receptors, VASTUS lateralis, PHOSPHORYLATION, FITNESS walking, MUSCLE contraction

Mechanisms Underlying Absent Training-Induced Improvement in Insulin Action in Lean, Hyperandrogenic Women With Polycystic Ovary Syndrome.

Authors: Hansen, Solvejg L., Bojsen-Møller, Kirstine N., Lundsgaard, Anne-Marie, Hendrich, Frederikke L., Nilas, Lisbeth, Sjøberg, Kim A., Hingst, Janne R., Serup, Annette K., Olguín, Carlos Henríquez, Carl, Christian S., Wernblad, Louise F., Henneberg, Marie, Lustrup, Katja M., Hansen, Christine, Jensen, Thomas E., Madsbad, Sten, Wojtaszewski, Jørgen F. P., Richter, Erik A., Kiens, Bente

Source: Diabetes; Nov2020, Vol. 69 Issue 11, p2267-2280, 14p

Subject Terms: POLYCYSTIC ovary syndrome, INSULIN, SKELETAL muscle, BLOOD flow, TYPE 2 diabetes, HOMEOSTASIS, RESEARCH, LIVER, TESTOSTERONE, RESEARCH methodology, EVALUATION research, MEDICAL cooperation, PHYSIOLOGICAL adaptation, COMPARATIVE studies, EXERCISE, HYPERANDROGENISM, OXIDATION-reduction reaction

491-P: Severe Muscle Insulin Resistance in Inuit Homozygous Carriers of the Common Greenlandic P.Arg684Ter TBC1D4 Variant Is Improved by a Single Bout of Exercise.

Authors: KRISTENSEN, JONAS M., LARSEN, TRINE L.J., CARL, CHRISTIAN S., THORUP, ANETTE, HINGST, JANNE, ONSLEV, JOHAN, OLESEN, JESPER S., PEDERSEN II, MICHAEL L., RICHTER, ERIK A., HANSEN, TORBEN, JØRGENSEN, MARIT E., WOJTASZEWSKI, JØRGEN F.P.

Source: Diabetes; 2021 Supplement 1, Vol. 70, pN.PAG-N.PAG, 1p