Real-world effectiveness and safety of bulevirtide monotherapy for up to 96 weeks in patients with HDV-related cirrhosis

Authors: Degasperi, Elisabetta ¹, Anolli, Maria Paola ¹, Jachs, Mathias ², Reiberger, Thomas ², De Ledinghen, Victor ³, Metivier, Sophie ⁴, D’Offizi, Gianpiero ⁵, di Maria, Francesco ⁵, Schramm, Christoph ⁶, Schmidt, Hartmut ⁶, Zöllner, Caroline ⁷, Tacke, Frank ⁷, Dietz-Fricke, Christopher ⁸, Wedemeyer, Heiner ⁸, Papatheodoridi, Margarita ⁹, Papatheodoridis, George ⁹, Carey, Ivana ¹⁰, Agarwal, Kosh ¹⁰, Van Bömmel, Florian ¹¹, Brunetto, Maurizia R. ¹², Cardoso, Mariana ¹³, Verucchi, Gabriella ¹⁴, Ciancio, Alessia ¹⁵, Zoulim, Fabien ¹⁶, Aleman, Soo ¹⁷, Semmo, Nasser ¹⁸, Mangia, Alessandra ¹⁹, Hilleret, Marie-Noelle ²⁰, Merle, Uta ²¹, Santantonio, Teresa A. ²², Coppola, Nicola ²³, Pellicelli, Adriano ²⁴, Roche, Bruno ²⁵, Causse, Xavier ²⁶, D’Alteroche, Louis ²⁷, Dumortier, Jérome ²⁸, Ganne, Nathalie ²⁹, Heluwaert, Frederic ³⁰, Ollivier, Isabelle ³¹, Roulot, Dominique ³², Viganò, Mauro ³³, Loglio, Alessandro ³⁴, Federico, Alessandro ³⁵, Pileri, Francesca ³⁶, Maracci, Monia ³⁷, Tonnini, Matteo ³⁸, Arpurt, Jean-Pierre ³⁹, Barange, Karl ⁴⁰, Billaud, Eric ⁴¹, Pol, Stanislas ⁴², Gervais, Anne ⁴³, Minello, Anne ⁴⁴, Rosa, Isabelle ⁴⁵, Puoti, Massimo ⁴⁶, Lampertico, Pietro ^{1, 47, 48, ⁎}

Source: In Journal of Hepatology December 2024

Assessing the virological response to direct-acting antiviral therapies in the HBV cure programme

Authors: Lok, James ^{a, ⁎}, Harris, James M. ^b, Carey, Ivana ^a, Agarwal, Kosh ^a, McKeating, Jane A. ^{b, c}

Source: In Virology April 2025 605

Hepatocellular carcinoma risk in sub-Saharan African and Afro-Surinamese individuals with chronic hepatitis B living in Europe

Authors: Patmore, Lesley A. ^{1, ∗}, van Eekhout, Kirsi M.A. ², Buti, Maria ³, Koc, Özgur.M. ⁴, Agarwal, Kosh ⁵, de Knegt, Rob J. ¹, Janssen, Harry L.A. ^{1, 6}, van der Valk, Marc ^{7, 8}, Lieveld, Faydra I. ^{9, 10}, Hansen, Bettina E. ^{11, 12}, Kramer, Matthijs ⁴, de Bruijne, Joep ⁹, Claassen, Mark A.A. ¹³, Smit, Colette ⁸, de Man, Rob A. ¹, Takkenberg, Bart ^{2, †}, Carey, Ivana ^{5, †}, Sonneveld, Milan J. ^{1, †}

Source: In Journal of Hepatology February 2024 80(2):243-250

Prediction of Hepatocellular Carcinoma and Liver-related Events in Anti-hepatitis D Virus-positive Individuals

Authors: Patmore, Lesley A., Spaan, Michelle, Agarwal, Kosh, Koc, Özgür M., Blokzijl, Hans, Brouwer, Samantha, van Soest, Hanneke, van Hulzen, Astrid G.W., Janssen, Harry L.A., Lammers, A.J. Jolanda, Jansen, Louis, Claassen, Mark, de Man, Robert A., Takkenberg, R. Bart, van Dijk, Remco, Posthouwer, Dirk, Reijnders, Jurriën G.P., Carey, Ivana, Sonneveld, Milan J.

Source: In Clinical Gastroenterology and Hepatology

HBV DNA and HBsAg Levels at 24 Weeks Off-Treatment Predict Clinical Relapse and HBsAg Loss in HBeAg-Negative Patients Who Discontinued Antiviral Therapy

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Janssen, Harry L., Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In Gastroenterology January 2024 166(1):168-177

Lower pretreatment HBV DNA levels are associated with better off-treatment outcomes after nucleo(s)tide analogue withdrawal in patients with HBeAg-negative chronic hepatitis B: A multicentre cohort study

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, Colombatto, Piero, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Brunetto, Maurizia, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: In JHEP Reports August 2023 5(8)

Universal versus targeted screening for HCV infection in pregnancy in a diverse, multi‐ethnic population: Universal screening is more comprehensive

Authors: Carey, Ivana, Christiana, Moigboi, Marie‐Ange, McLeod, Teresa, Bowyer, Maria, Guerra Veloz, Dusheiko, Geoff, Agarwal, Kosh

Source: Journal of viral hepatitis. 29(12):1079-1088

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182070088.0x000001&indx=1&recIds=ETOCvdc_100182070088.0x000001

Probability of HBsAg loss after nucleo(s)tide analogue withdrawal depends on HBV genotype and viral antigen levels

Authors: Sonneveld, Milan J., Chiu, Shao-Ming, Park, Jun Yong, Brakenhoff, Sylvia M., Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Höner zu Siederdissen, Christoph, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Chen, Chien-Hung, Maasoumy, Benjamin

Source: Journal of hepatology. 76(5):1042-1050

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179671421.0x000001&indx=1&recIds=ETOCvdc_100179671421.0x000001

A case of HBV-induced liver failure in the REEF-2 phase II trial: Implications for finite treatment strategies in HBV 'cure'

Authors: Agarwal, Kosh, Lok, James, Carey, Ivana, Shivkar, Yatin, Biermer, Michael, Berg, Thomas, Lonjon-Domanec, Isabelle

Source: Journal of hepatology. 77(1):245-248

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165884345.0x000001&indx=1&recIds=ETOCvdc_100165884345.0x000001

Review article: novel biomarkers in hepatitis B infection

Authors: Lok, James, Dusheiko, Geoffrey, Carey, Ivana, Agarwal, Kosh

Source: Alimentary pharmacology & therapeutics. 56(5):760-776

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157739660.0x000001&indx=1&recIds=ETOCvdc_100157739660.0x000001

Prediction of Sustained Response After Nucleo(s)tide Analogue Cessation Using HBsAg and HBcrAg Levels: A Multicenter Study (CREATE)

Authors: Sonneveld, Milan J., Park, Jun Yong, Kaewdech, Apichat, Seto, Wai-Kay, Tanaka, Yasuhito, Carey, Ivana, Papatheodoridi, Margarita, van Bömmel, Florian, Berg, Thomas, Zoulim, Fabien, Ahn, Sang Hoon, Dalekos, George N., Erler, Nicole S., Höner zu Siederdissen, Christoph, Wedemeyer, Heiner, Cornberg, Markus, Yuen, Man-Fung, Agarwal, Kosh, Boonstra, Andre, Buti, Maria, Piratvisuth, Teerha, Papatheodoridis, George, Maasoumy, Benjamin

Source: Clinical gastroenterology and hepatology. 20(4):e784-e793

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157349932.0x000001&indx=1&recIds=ETOCvdc_100157349932.0x000001

Mitochondrial dysfunction as a mechanistic biomarker in patients with non-alcoholic fatty liver disease (NAFLD)

Authors: Ajaz, Saima, McPhail, Mark J., Gnudi, Luigi, Trovato, Francesca M., Mujib, Salma, Napoli, Salvatore, Carey, Ivana, Agarwal, Kosh

Source: In Mitochondrion March 2021 57:119-130

Hepatitis B Core-Related Antigen to Indicate High Viral Load: Systematic Review and Meta-Analysis of 10,397 Individual Participants

Authors: Yoshida, Kyoko, Desbiolles, Alice, Feldman, Sarah F., Ahn, Sang Hoon, Alidjinou, Enagnon K., Atsukawa, Masanori, Bocket, Laurence, Brunetto, Maurizia R., Buti, Maria, Carey, Ivana, Caviglia, Gian Paolo, Chen, En-Qiang, Cornberg, Markus, Enomoto, Masaru, Honda, Masao, Zu Siederdissen, Christoph Höner, Ishigami, Masatoshi, Janssen, Harry L.A., Maasoumy, Benjamin, Matsui, Takeshi, Matsumoto, Akihiro, Nishiguchi, Shuhei, Riveiro-Barciela, Mar, Takaki, Akinobu, Tangkijvanich, Pisit, Toyoda, Hidenori, van Campenhout, Margo J.H., Wang, Bo, Wei, Lai, Yang, Hwai-I, Yano, Yoshihiko, Yatsuhashi, Hiroshi, Yuen, Man-Fung, Tanaka, Eiji, Lemoine, Maud, Tanaka, Yasuhito, Shimakawa, Yusuke

Source: In Clinical Gastroenterology and Hepatology January 2021 19(1):46-60

Incremental value of HBcrAg to classify 1582 HBeAg‐negative individuals in chronic infection without liver disease or hepatitis

Authors: Brunetto, Maurizia R., Carey, Ivana, Maasoumy, Benjamin, Marcos‐Fosch, Cristina, Boonstra, André, Caviglia, Gian Paolo, Loglio, Alessandro, Cavallone, Daniela, Scholtes, Caroline, Ricco, Gabriele, Smedile, Antonina, Riveiro‐Barciela, Mar, Bömmel, Florian, Eijk, Annemiek, Zoulim, Fabien, Berg, Thomas, Cornberg, Markus, Lampertico, Pietro, Agarwal, Kosh, Buti, Maria

Source: Alimentary pharmacology & therapeutics. 53(6):733-744

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A clinical risk score to identify patients with COVID-19 at high risk of critical care admission or death: An observational cohort study

Authors: Galloway, James B, Norton, Sam, Barker, Richard D, Brookes, Andrew, Carey, Ivana, Clarke, Benjamin D, Jina, Raeesa, Reid, Carole, Russell, Mark D, Sneep, Ruth, Sugarman, Leah, Williams, Sarah, Yates, Mark, Teo, James, Shah, Ajay M, Cantle, Fleur

Source: In Journal of Infection August 2020 81(2):282-288

Hepatitis delta genotype 5 is associated with favourable disease outcome and better response to treatment compared to genotype 1

Authors: Spaan, Michelle, Carey, Ivana, Bruce, Matthew, Shang, Dazhuang, Horner, Mary, Dusheiko, Geoff, Agarwal, Kosh

Source: In Journal of Hepatology June 2020 72(6):1097-1104

Pregenomic HBV RNA and Hepatitis B Core‐Related Antigen Predict Outcomes in Hepatitis B e Antigen–Negative Chronic Hepatitis B Patients Suppressed on Nucleos(T)ide Analogue Therapy

Authors: Carey, Ivana, Gersch, Jeffrey, Wang, Bo, Moigboi, Christiana, Kuhns, Mary, Cloherty, Gavin, Dusheiko, Geoffrey, Agarwal, Kosh

Source: Hepatology. 72(1):42-57

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Interferon-free direct-acting antiviral therapy for acute hepatitis C virus infection in HIV-infected individuals: A literature review

Authors: Lampejo, Temi, Agarwal, Kosh, Carey, Ivana

Source: In Digestive and Liver Disease February 2018 50(2):113-123

Hepatitis D infection in a HBsAg cohorts referred from specialist liver clinics vs. reflex community referred patients in South East London

Authors: Carey, Ivana, Lok, James, Veloz, Maria Guerra, Moigboi, Christiana, Dusheiko, Geoffrey, Agarwal, Kosh

Source: Journal of hepatology. 78(S1):S905-S906

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HDV genotypes have an impact on pegylated interferon therapy response and long-term liver disease related outcomes

Authors: Carey, Ivana, Bolton, Natalie, Anderson, Mark, Lok, James, Moigboi, Christiana, Cloherty, Gavin, Dusheiko, Geoffrey, Agarwal, Kosh

Source: Journal of hepatology. 78(S1):S1081-S1082

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195500048.0x000001&indx=1&recIds=ETOCvdc_100195500048.0x000001