Selective dopaminergic neurotoxicity modulated by inherent cell-type specific neurobiology

Authors: Currim, Fatema, Tanwar, Reeya, Brown-Leung, Josephine M., Paranjape, Neha, Liu, Jennifer, Sanders, Laurie H., Doorn, Jonathan A., Cannon, Jason R.

Source: In Neurotoxicology July 2024 103:266-287

Nuclear DNA and Mitochondrial Damage of the Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine in Human Neuroblastoma Cells

Authors: Bellamri, Medjda, Brandt, Kyle, Cammerrer, Kari, Syeda, Tauqeerunnisa, Turesky, Robert J., Cannon, Jason R.

Source: Chemical research in toxicology. 36(8):1361-1373

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633631852&indx=1&recIds=ETOCRN633631852

Lipid metabolism in dopaminergic neurons influences light entrainment

Authors: Fernandez, Regina F., Wilson, Emily S., Diaz, Victoria, Martínez‐Gardeazabal, Jonatan, Foguth, Rachel, Cannon, Jason R., Jackson, Shelley N., Hermann, Brian P., Eells, Jeffrey B., Ellis, Jessica M.

Source: Journal of neurochemistry. 165(3):379-390

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182210053.0x000001&indx=1&recIds=ETOCvdc_100182210053.0x000001

Paraquat exposure produces sex-dependent reduction in binge-like alcohol drinking in high alcohol-preferring mice

Authors: Enkh-Amgalan, Soyol, Brown-Leung, Josephine M., Syeda, Tauqeerunnisa, Nolan, Rachel M., Cannon, Jason R., Chester, Julia A.

Source: In Food and Chemical Toxicology April 2023 174

Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes

Authors: Brown-Leung, Josephine M., Cannon, Jason R.

Source: Chemical research in toxicology. 35(8):1312-1333

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631525050&indx=1&recIds=ETOCRN631525050

Potential Role of Heterocyclic Aromatic Amines in Neurodegeneration

Authors: Syeda, Tauqeerunnisa, Cannon, Jason R.

Source: Chemical research in toxicology. 35(1):59-72

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631523910&indx=1&recIds=ETOCRN631523910

Demyelination and impaired oligodendrogenesis in the corpus callosum following lead exposure.

Authors: Liu, Luke L, Emir, Uzay, Gu, Huiying, Sang, Lara T, Sawiak, Stephen J, Cannon, Jason R, Du, Yansheng, Zheng, Wei

Source: Toxicological Sciences; Nov2024, Vol. 202 Issue 1, p123-141, 19p

Subject Terms: LEAD exposure, CORPUS callosum, ALZHEIMER'S disease, CHOROID plexus, MULTIPLE sclerosis

Neuromelanin formation exacerbates HAA-induced mitochondrial toxicity and mitophagy impairments

Authors: Lawana, Vivek, Um, Se Young, Foguth, Rachel M., Cannon, Jason R. ^*

Source: In Neurotoxicology December 2020 81:147-160

PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer’s disease

Authors: Syeda, Tauqeerunnisa, Foguth, Rachel M., Llewellyn, Emily, Cannon, Jason R. ^*

Source: In Toxicology 15 May 2020 437

Localization of Fluorescent Targets in Deep Tissue With Expanded Beam Illumination for Studies of Cancer and the Brain

Authors: Bentz, Brian Z., Mahalingam, Sakkarapalayam M., Ysselstein, Daniel, Montenegro Larrea, Paola C., Cannon, Jason R., Rochet, Jean-Christophe, Low, Philip S., Webb, Kevin

Source: IEEE transactions on medical imaging. 39(7):2472-2481

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100102769550.0x000001&indx=1&recIds=ETOCvdc_100102769550.0x000001

Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity

Authors: Lawana, Vivek, Um, Se Young, Rochet, Jean-Christophe, Turesky, Robert J, Shannahan, Jonathan H, Cannon, Jason R

Source: Toxicological sciences. 173(1):171-188

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097148676.0x000001&indx=1&recIds=ETOCvdc_100097148676.0x000001

Acyl-CoA synthetase 6 enriches the neuroprotective omega-3 fatty acid DHA in the brain

Authors: Fernandez, Regina F., Kim, Sora Q., Zhao, Yingwei, Foguth, Rachel M., Weera, Marcus M., Counihan, Jessica L., Nomura, Daniel K., Chester, Julia A., Cannon, Jason R., Ellis, Jessica M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Dec 01. 115(49), 12525-12530.

Access URL: https://www.jstor.org/stable/26573694

Selective dopaminergic neurotoxicity of three heterocyclic amine subclasses in primary rat midbrain neurons

Authors: Cruz-Hernandez, Angela, Agim, Zeynep Sena, Montenegro, Paola C., McCabe, George P., Rochet, Jean-Christophe, Cannon, Jason R.

Source: In Neurotoxicology March 2018 65:68-84

Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans

Authors: Sammi, Shreesh Raj, Foguth, Rachel M, Nieves, Claudia Sofía, De Perre, Chloe, Wipf, Peter, McMurray, Cynthia T, Lee, Linda S, Cannon, Jason R

Source: Toxicological sciences. 172(2):417-434

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094766786.0x000001&indx=1&recIds=ETOCvdc_100094766786.0x000001

Alterations in the nigrostriatal dopamine system after acute systemic PhIP exposure

Authors: Agim, Zeynep Sena, Cannon, Jason R.

Source: Toxicology letters. 287:31-41

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181287325.0x000001&indx=1&recIds=ETOCvdc_100181287325.0x000001

From the Cover: Harmane-Induced Selective Dopaminergic Neurotoxicity in Caenorhabditis elegans

Authors: Sammi, Shreesh Raj, Agim, Zeynep Sena, Cannon, Jason R

Source: Toxicological sciences. 161(2):335-348

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081729644.0x000001&indx=1&recIds=ETOCvdc_100081729644.0x000001

Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP+ exposure

Authors: Dukes, April A., Bai, Qing, Van Laar, Victor S., Zhou, Yangzhong, Ilin, Vladimir, David, Christopher N., Agim, Zeynep S., Bonkowsky, Joshua L., Cannon, Jason R., Watkins, Simon C., Croix, Claudette M. St., Burton, Edward A., Berman, Sarah B.

Source: In Neurobiology of Disease November 2016 95:238-249

Developmental origins of neurotransmitter and transcriptome alterations in adult female zebrafish exposed to atrazine during embryogenesis

Authors: Wirbisky, Sara E., Weber, Gregory J., Sepúlveda, Maria S., Xiao, Changhe, Cannon, Jason R., Freeman, Jennifer L.

Source: In Toxicology 3 July 2015 333:156-167

Environmental exposures and the etiopathogenesis of Alzheimer's disease: The potential role of BACE1 as a critical neurotoxic target

Authors: Syeda, Tauqeerunnisa, Cannon, Jason R.

Source: Journal of biochemical and molecular toxicology. 35(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120115470.0x000001&indx=1&recIds=ETOCvdc_100120115470.0x000001

Post-status epilepticus treatment with the cannabinoid agonist WIN 55,212-2 prevents chronic epileptic hippocampal damage in rats

Authors: Di Maio, Roberto, Cannon, Jason R., Greenamyre, J. Timothy

Source: In Neurobiology of Disease January 2015 73:356-365