GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma

Authors: Marta Moreno, Leire Pedrosa, Laia Paré, Estela Pineda, Leire Bejarano, Josefina Martínez, Veerakumar Balasubramaniyan, Ravesanker Ezhilarasan, Naveen Kallarackal, Sung-Hak Kim, Jia Wang, Alessandra Audia, Siobhan Conroy, Mercedes Marin, Teresa Ribalta, Teresa Pujol, Antoni Herreros, Avelina Tortosa, Helena Mira, Marta M. Alonso, Candelaria Gómez-Manzano, Francesc Graus, Erik P. Sulman, Xianhua Piao, Ichiro Nakano, Aleix Prat, Krishna P. Bhat, Núria de la Iglesia

Source: Cell Reports, Vol 21, Iss 8, Pp 2183-2197 (2017)

Subject Terms: GPR56, glioblastoma, mesenchymal differentiation, radioresistance, NF-κB, glioma stem-like initiating cell, tumor plasticity, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717315462; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/a26249bc3090411b9bb7ed6f862f62c4

Oncolytic adenoviruses and immunopeptidomics: a convenient marriage

Authors: Marc Garcia‐Moure, Andrew G. Gillard, Marta M. Alonso, Juan Fueyo, Candelaria Gomez‐Manzano

Source: Molecular Oncology, Vol 18, Iss 4, Pp 781-784 (2024)

Subject Terms: adenovirus, cancer, mesothelioma, personalized, vaccine, virotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/f196420c54cc4f3dabd5e868f56a064a

Oncolytic Virotherapies and Adjuvant Gut Microbiome Therapeutics to Enhance Efficacy Against Malignant Gliomas

Authors: Natalie M. Meléndez-Vázquez, Candelaria Gomez-Manzano, Filipa Godoy-Vitorino

Source: Viruses, Vol 16, Iss 11, p 1775 (2024)

Subject Terms: viroimmunotherapy, therapeutic efficacy, gut microbiome, glioblastoma, combinatory therapies, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/11/1775; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/88f00ba602f94a8c850e3ee79b14dab6

Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

Authors: Natalie M. Meléndez-Vázquez, Teresa T. Nguyen, Xuejun Fan, Andrés R. López-Rivas, Juan Fueyo, Candelaria Gomez-Manzano, Filipa Godoy-Vitorino

Source: Molecular Therapy: Oncology, Vol 32, Iss 2, Pp 200801- (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950329924000432; https://doaj.org/toc/2950-3299

Access URL: https://doaj.org/article/e21a353f48e2483eba24e6e6f9e54ab8

Gut microbiota composition is associated with the efficacy of Delta-24-RGDOX in malignant gliomas

Authors: Natalie M. Meléndez-Vázquez, Teresa T. Nguyen, Xuejun Fan, Andrés R. López-Rivas, Juan Fueyo, Candelaria Gomez-Manzano, Filipa Godoy-Vitorino

Source: Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200787- (2024)

Subject Terms: MT: Regular Issue, gut microbiota, viroimmunotherapy, glioblastoma, oncolytic virus, Delta-24-RGDOX, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950329924000298; https://doaj.org/toc/2950-3299

Access URL: https://doaj.org/article/05dc18ff379449b4a636ef9d63769adf

Combining CAR T Cell Therapy and Oncolytic Virotherapy for Pediatric Solid Tumors: A Promising Option

Authors: Jiasen He, Faryal Munir, Dristhi Ragoonanan, Wafik Zaky, Sajad J Khazal, Priti Tewari, Juan Fueyo, Candelaria Gomez-Manzano, Hong Jiang

Source: Immuno, Vol 3, Iss 1, Pp 37-56 (2023)

Subject Terms: CAR T cell therapy, oncolytic virus, oncolytic virotherapy, pediatric solid tumor, pediatric brain tumor, cancer immunotherapy, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2673-5601/3/1/4; https://doaj.org/toc/2673-5601

Access URL: https://doaj.org/article/8e21df740cd0464fbcca79ba81b98086

Remission of liquid tumors and SARS-CoV-2 infection: A literature review

Authors: Dong Ho Shin, Andrew Gillard, Arie Van Wieren, Candelaria Gomez-Manzano, Juan Fueyo

Source: Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 135-140 (2022)

Subject Terms: SARS-CoV-2, cancer, oncolytic viruses, liquid tumors, virotherapy, immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770522000845; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/80e5c441651548548affde0fe56ecf09

Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry

Authors: Filipa Godoy-Vitorino, Hong Jiang, W Jim Zheng, Frederick F Lang, Joy Gumin, Lisha Zhu, Candelaria Gomez-Manzano, Juan Fueyo, Derek A Wainwright, Dong Ho Shin, Teresa T Nguyen, Sagar Sohoni, Sanjay K Singh, Yisel Rivera-Molina, Xuejun Fan, Christopher Alvarez-Breckenridge, Lijie Zhai, Erik Ladomersky, Kristen L Lauing, Marta M Alonso

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/7/e004935.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/1f2db7df16d848f1a1f3ecf672c1450b

Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas

Authors: Virginia Laspidea, Montserrat Puigdelloses, Sara Labiano, Lucía Marrodán, Marc Garcia-Moure, Marta Zalacain, Marisol Gonzalez-Huarriz, Naiara Martínez-Vélez, Iker Ausejo-Mauleon, Daniel de la Nava, Guillermo Herrador-Cañete, Javier Marco-Sanz, Elisabeth Guruceaga, Carlos E. de Andrea, María Villalba, Oren Becher, Massimo Squatrito, Verónica Matía, Jaime Gállego Pérez-Larraya, Ana Patiño-García, Sumit Gupta, Candelaria Gomez-Manzano, Juan Fueyo, Marta M. Alonso

Source: JCI Insight, Vol 7, Iss 7 (2022)

Subject Terms: Immunology, Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/ce5f44e54382422bab0de99c10b63d55

745 Oncolytic adenovirus expressing 4-1BBL demonstrates a significant increase of survival in Diffuse Midline Glioma models

Authors: Sara Labiano, Candelaria Gomez-Manzano, Juan Fueyo, Marta Alonso, Ana Patiño-García, Marc Garcia-Moure, Virginia Laspidea, Iker Ausejo-Mauleon, Daniel de la Nava, Javier Marco-Sanz

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/6e2189ebb3a6425bb8dd7c09207e3862

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Authors: Naiara Martínez-Vélez, Marc Garcia-Moure, Miguel Marigil, Marisol González-Huarriz, Montse Puigdelloses, Jaime Gallego Pérez-Larraya, Marta Zalacaín, Lucía Marrodán, Maider Varela-Guruceaga, Virginia Laspidea, Jose Javier Aristu, Luis Isaac Ramos, Sonia Tejada-Solís, Ricardo Díez-Valle, Chris Jones, Alan Mackay, Jose A. Martínez-Climent, Maria Jose García-Barchino, Eric Raabe, Michelle Monje, Oren J. Becher, Marie Pierre Junier, Elias A. El-Habr, Herve Chneiweiss, Guillermo Aldave, Hong Jiang, Juan Fueyo, Ana Patiño-García, Candelaria Gomez-Manzano, Marta M. Alonso

Source: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e70b68b3d2c14bafb5f5185c1fba26c6

Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models

Authors: Naiara Martinez-Velez, Miguel Marigil, Marc García-Moure, Marisol Gonzalez-Huarriz, Jose Javier Aristu, Luis-Isaac Ramos-García, Sonia Tejada, Ricardo Díez-Valle, Ana Patiño-García, Oren J. Becher, Candelaria Gomez-Manzano, Juan Fueyo, Marta M. Alonso

Source: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)

Subject Terms: pHGG, DIPG, Radiotherapy, Oncolytic virus, DNA damage, Immune response, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0714-6; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/48ebc806f5dd44a9b7c4cdfd3de87468

CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models

Authors: Hong Jiang, Sandra Hervás-Stubbs, Sara Labiano, Candelaria Gomez-Manzano, Juan Fueyo, Marta Alonso, Zhihong Chen, Montserrat Puigdelloses, Marc Garcia-Moure, Virginia Laspidea, Marisol Gonzalez-Huarriz, Marta Zalacain, Lucia Marrodan, Naiara Martinez-Velez, Daniel De la Nava, Iker Ausejo, Guillermo Herrador, Dolores Hambardzumyan, Ana Patino Garcia, Jaime Gállego Pérez-Larraya

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/7/e002644.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/8be1f4dbef0b424cad2a180d4cd44aa1

Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model

Authors: Konrad Gabrusiewicz, Mohammad B. Hossain, Nahir Cortes-Santiago, Xuejun Fan, Bozena Kaminska, Frank C. Marini, Juan Fueyo, Candelaria Gomez-Manzano

Source: Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 4, Pp 374-384 (2015)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558615000433; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/fc2bb8b520ba489e80e4494559aacdb1

Analysis of SOX2-Regulated Transcriptome in Glioma Stem Cells.

Authors: Arlet M Acanda de la Rocha, Hernando López-Bertoni, Elizabeth Guruceaga, Marisol González-Huarriz, Naiara Martínez-Vélez, Enric Xipell, Juan Fueyo, Candelaria Gomez-Manzano, Marta M Alonso

Source: PLoS ONE, Vol 11, Iss 9, p e0163155 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5036841?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fb1c84dbab4f4d5d9440a7051af303c3

Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens.

Authors: Sarah R Klein, Hong Jiang, Mohammad B Hossain, Xuejun Fan, Joy Gumin, Andrew Dong, Marta M Alonso, Candelaria Gomez-Manzano, Juan Fueyo

Source: PLoS ONE, Vol 11, Iss 4, p e0153814 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4836716?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/49e85eada63540aea48f4896c19713de

Sustained Angiopoietin-2 Expression Disrupts Vessel Formation and Inhibits Glioma Growth

Authors: Ok-Hee Lee, Juan Fueyo, Jing Xu, W.K. Alfred Yung, Michael G. Lemoine, Frederick F. Lang, B. Nebiyou Bekele, Xian Zhou, Marta A. Alonso, Kenneth D. Aldape, Gregory N. Fuller, Candelaria Gomez-Manzano

Source: Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 5, Pp 419-428 (2006)

Subject Terms: Glioma, animal model, vascular development, tumor growth, angiopoietin-2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S147655860680062X; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/41665a8cfb5c454690dd1f420d813435

Downmodulation of El A Protein Expression as a Novel Strategy to Design Cancer-Selective Adenoviruses

Authors: Hong Jiang, Ramon Alemany, Candelaria Gomez-Manzano, Diana R. Medrano, Michael G. Lemoine, Melissa V. Olson, Marta M. Alonso, Ok-Hee Lee, Charles C. Conrad, W.K. Alfred Yung, Juan Fueyo

Source: Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 8, Pp 723-729 (2005)

Subject Terms: glioma, oncolytic, adenovirus, E1A, CR1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558605801046; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/491e1777705e404cb344c8429991fbba

Comparative Effect of Oncolytic Adenoviruses with E1 A or E113-55 kDa Deletions in Malignant Gliomas

Authors: Hong Jiang, Candelaria Gomez-Manzano, Ramon Alemany, Diana Medrano, Marta Alonso, B. Nebiyou Bekele, E Lin, Charles C. Conrad, W.K. Alfred Yung, Juan Fueyo

Source: Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 1, Pp 48-56 (2005)

Subject Terms: Glioma, oncolytic adenovirus, E1 A, E1 B, fiber protein, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558605800983; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/cdc230a3a8e047199bdf531cff013156

Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model.

Authors: Hong Jiang, Karen Clise-Dwyer, Kathryn E Ruisaard, Xuejun Fan, Weihua Tian, Joy Gumin, Martine L Lamfers, Anne Kleijn, Frederick F Lang, Wai-Kwan Alfred Yung, Luis M Vence, Candelaria Gomez-Manzano, Juan Fueyo

Source: PLoS ONE, Vol 9, Iss 5, p e97407 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4020829?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fb4673f3b2904821a7d5b9efeabd6a3b