Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML

Authors: Sekeres, Mikkael A., Watts, Justin, Radinoff, Atanas, Sangerman, Montserrat Arnan, Cerrano, Marco, Lopez, Patricia Font, Zeidner, Joshua F., Campelo, Maria Diez, Graux, Carlos, Liesveld, Jane, Selleslag, Dominik, Tzvetkov, Nikolay, Fram, Robert J., Zhao, Dan, Bell, Jill, Friedlander, Sharon, Faller, Douglas V., Adès, Lionel

Source: Leukemia. 35(7):2119-2124

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MDS-110 SELECT-MDS-1 Trial in Progress: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Tamibarotene/Azacitidine Versus Placebo/Azacitidine in Newly Diagnosed Adult Patients Selected for RARA-Positive Higher-Risk MDS

Authors: DeZern, Amy ¹, Fenaux, Pierre ², Deeren, Dries ³, Campelo, Maria Diez ⁴, Lübbert, Michael ⁵, Krishnamurthy, Pramila ⁶, Nagy, Zsolt ⁷, Basak, Grzegorz ⁸, ová, Anna Jonáš ⁹, Geissler, Klaus ¹⁰, Ofran, Yishai ¹¹, Volkert, Angela ¹², Baker, Kristen ¹², Chisholm, Jaime ¹², Kang-Fortner, Qing ¹², Roth, David A. ¹², Kelly, Michael ¹², Marconi, Giovanni ¹³

Source: In Clinical Lymphoma, Myeloma and Leukemia October 2022 22 Supplement 2:S303-S304

MDS-344: Pevonedistat Plus Azacitidine vs Azacitidine Alone in Higher-Risk Myelodysplastic Syndromes (MDS): Efficacy and Safety Results from Study P-2001 (NCT02610777)

Authors: Watts, Justin, Sekeres, Mikkael, Radinoff, Atanas, Arnan, Montserrat, Cerrano, Marco, Lopez, Patricia Font, Zeidner, Joshua, Campelo, Maria Diez, Graux, Carlos, Liesveld, Jane, Selleslag, Dominik, Tzvetkov, Nikolai, Fram, Robert, Zhao, Dan, Friedlander, Sharon, Galinsky, Kevin, Faller, Douglas, Adès, Lionel

Source: Clinical lymphoma, myeloma & leukemia. 21(S1):S347-S348

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Poster: MDS-110 SELECT-MDS-1 Trial in Progress: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of Tamibarotene/Azacitidine Versus Placebo/Azacitidine in Newly Diagnosed Adult Patients Selected for RARA-positive Higher-Risk MDS

Authors: DeZern, Amy, Fenaux, Pierre, Deeren, Dries, Campelo, Maria Diez, Lübbert, Michael, Krishnamurthy, Pramila, Nagy, Zsolt, Basak, Grzegorz, ová, Anna Jonáš, Geissler, Klaus, Ofran, Yishai, Volkert, Angela, Baker, Kristen, Chisholm, Jaime, Kang-Fortner, Qing, Roth, David A., Kelly, Michael, Marconi, Giovanni

Source: Clinical lymphoma, myeloma & leukemia. 22(S2):S150-S150

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172884554.0x000001&indx=1&recIds=ETOCvdc_100172884554.0x000001

MDS-336: Phase 2 Study of Pevonedistat + Azacitidine versus Azacitidine in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)/Chronic Myelomonocytic Leukemia (CMML) or Low-Blast Acute Myelogenous Leukemia (LB-AML) (NCT02610777): Subset Analysis in Higher-Risk MDS

Authors: Watts, Justin, Adès, Lionel, Radinoff, Atanas, Sangerman, Montserrat Arnan, Cerrano, Marco, Lopez, Patricia Font, Zeidner, Joshua, Campelo, Maria Diez, Graux, Carlos, Liesveld, Jane, Selleslag, Dominik, Tzvetkov, Nikolay, Fram, Robert J., Zhao, Dan, Bell, Jill, Friedlander, Sharon, Faller, Douglas V., Sekeres, Mikkael A.

Source: Clinical lymphoma, myeloma & leukemia. 20(S1):S323-S324

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Outcome of lower-risk myelodysplastic syndrome with ring sideroblasts (MDS-RS) after failure of erythropoiesis- stimulating agents

Authors: Park, Sophie ^*, Hamel, Jean-François, Toma, Andrea, Kelaidi, Charikleia, Thépot, Sylvain, Campelo, Maria Díez, Santini, Valeria, Sekeres, Mikkael A., Komrokji, Rami, Steensma, David, Balleari, Enrico, Götze, Katharina S., Kotsianidis, Ioannis, Guerci- Bresler, Agnès, Stamatoullas, Aspasia, Sanz, Guillermo F., Germing, Ulrich, Fenaux, Pierre

Source: In Leukemia Research December 2020 99

Poster: MDS-344: Pevonedistat Plus Azacitidine vs Azacitidine Alone in Higher-Risk Myelodysplastic Syndromes (MDS): Efficacy and Safety Results from Study P-2001 (NCT02610777)

Authors: Watts, Justin, Sekeres, Mikkael, Radinoff, Atanas, Arnan, Montserrat, Cerrano, Marco, Lopez, Patricia Font, Zeidner, Joshua, Campelo, Maria Diez, Graux, Carlos, Liesveld, Jane, Selleslag, Dominik, Tzvetkov, Nikolai, Fram, Robert, Zhao, Dan, Friedlander, Sharon, Galinsky, Kevin, Faller, Douglas, Adès, Lionel

Source: Clinical lymphoma, myeloma & leukemia. 21(S1):S227-S227

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100137350844.0x000001&indx=1&recIds=ETOCvdc_100137350844.0x000001

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The Use of 5-Azacitidine in Allogeneic Hematopoietic Cell Transplantation: A Single Center Experience

Authors: Martin Lopez, Ana A., Campelo, Maria Diez, Porras, Silvia Rojas, Guijo, Alba Redondo, Corral, Lucia Lopez, Guijo, Fermin Sanchez, del Canizo, Consuelo

Source: Biology of blood and marrow transplantation. 19(2):S298-S299

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Guiding the Global Evolution of Cytogenetic Testing for Hematologic Malignancies

Authors: Akkari, Yassmine M.N., Baughn, Linda B., Dubuc, Adrian M., Smith, Adam C., Mallo, Mar, Cin, Paola Dal, del Campelo, Maria Diez, Gallego, Marta S., Font, Isabel Granada, Haase, Detlef T., Schlegelberger, Brigitte, Slavutsky, Irma, Mecucci, Cristina, Levine, Ross L., Hasserjian, Robert P., Solé, Francesc, Levy, Brynn, Xu, Xinjie

Source: Blood; 20220101, Issue: Preprints

Both Expanded and Uncultured Mesenchymal Stem Cells from MDS Patients Are Genomically Abnormal, Showing a Specific Genetic Profile for the 5q- Syndrome.

Authors: Villar, Olga López ^*, García, Juan LuíS. ^*, Guijo, Fermín. M Sánchez ^*, Robledo, Cristina ^*, Campo, Pilar Hernandez ^*, Campelo, Maria Diez ^*, Muntion, Sandra ^*, Simón, Jose Antonio Pérez ^*, Miguel, J.F. San, Cañizo, MaríA. Consuelo Del ^*

Source: In Blood 16 November 2008 112(11):1650-1650

Correction to: Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML

Authors: Sekeres, Mikkael A., Watts, Justin, Radinoff, Atanas, Sangerman, Montserrat Arnan, Cerrano, Marco, Lopez, Patricia Font, Zeidner, Joshua F., Campelo, Maria Diez, Graux, Carlos, Liesveld, Jane, Selleslag, Dominik, Tzvetkov, Nikolay, Fram, Robert J., Zhao, Dan, Bell, Jill, Friedlander, Sharon, Faller, Douglas V., Adès, Lionel

Source: Leukemia; December 2021, Vol. 35 Issue: 12 p3637-3637, 1p

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