Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study

Authors: Cavo, Michele ^*, Gay, Francesca, Beksac, Meral, Pantani, Lucia, Petrucci, Maria Teresa, Dimopoulos, Meletios A, Dozza, Luca, van der Holt, Bronno, Zweegman, Sonja, Oliva, Stefania, van der Velden, Vincent H J, Zamagni, Elena, Palumbo, Giuseppe A, Patriarca, Francesca, Montefusco, Vittorio, Galli, Monica, Maisnar, Vladimir, Gamberi, Barbara, Hansson, Markus, Belotti, Angelo, Pour, Ludek, Ypma, Paula, Grasso, Mariella, Croockewit, Alexsandra, Ballanti, Stelvio, Offidani, Massimo, Vincelli, Iolanda D, Zambello, Renato, Liberati, Anna Marina, Andersen, Niels Frost, Broijl, Annemiek, Troia, Rossella, Pascarella, Anna, Benevolo, Giulia, Levin, Mark-David, Bos, Gerard, Ludwig, Heinz, Aquino, Sara, Morelli, Anna Maria, Wu, Ka Lung, Boersma, Rinske, Hajek, Roman, Durian, Marc, von dem Borne, Peter A, Caravita di Toritto, Tommaso, Zander, Thilo, Driessen, Christoph, Specchia, Giorgina, Waage, Anders, Gimsing, Peter, Mellqvist, Ulf-Henrik, van Marwijk Kooy, Marinus, Minnema, Monique, Mandigers, Caroline, Cafro, Anna Maria, Palmas, Angelo, Carvalho, Susanna, Spencer, Andrew, Boccadoro, Mario, Sonneveld, Pieter

Source: In The Lancet Haematology June 2020 7(6):e456-e468

Bortezomib, cyclophosphamide, dexamethasone versus lenalidomide, cyclophosphamide, dexamethasone in multiple myeloma patients at first relapse

Authors: Montefusco, Vittorio, Corso, Alessandro, Galli, Monica, Ardoino, Ilaria, Pezzatti, Sara, Carniti, Cristina, Patriarca, Francesca, Gherlinzoni, Filippo, Zambello, Renato, Sammassimo, Simona, Marcatti, Magda, Nozza, Andrea, Crippa, Claudia, Cafro, Anna Maria, Baldini, Luca, Corradini, Paolo

Source: British journal of haematology. 188(6):907-917

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103344319.0x000001&indx=1&recIds=ETOCvdc_100103344319.0x000001

Anti-CD38 monoclonal antibody impairs CD34+ mobilization and affects clonogenic potential in multiple myeloma patients.

Authors: Zappaterra, Arianna, Civettini, Ivan, Cafro, Anna Maria, Pezzetti, Laura, Pierini, Silvia, Anghilieri, Michela, Bellio, Laura, Bertazzoni, Paola, Grillo, Giovanni, Minga, Periana, Pioltelli, Maria L., Ravano, Emanuele, Sassone, Marianna, Viganò, Clara V., Volpato, Elisabetta B., Gambacorti-Passerini, Carlo, Rossini, Silvano, Cairoli, Roberto, Crocchiolo, Roberto

Source: Blood Transfusion (17232007); Jul/Aug2024, Vol. 22 Issue 4, p328-337, 10p

Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial

Authors: Bar, Daniel, Basso, Alfredo, Fantl, Dorotea, He, Simon, Horvath, Neomi, Lee, Cindy, Rowlings, Phillip, Taylor, Kerry, Spencer, Andrew, Cochrane, Tara, Kwok, Fiona, Ramanathan, Sundreswran, Agis, Hermine, Zojer, Niklas, Kentos, Alain, Offner, Fritz, Van Droogenbroeck, Jan, Wu, Ka Lung, Maiolino, Angelo, Martinez, Gracia, Zanella, Karla, Capra, Marcelo, Araújo, Sérgio, Gregora, Evzen, Hajek, Roman, Maisnar, Vladimir, Pour, Ludek, Scudla, Vlastimil, Spicka, Ivan, Abildgaard, Niels, Andersen, Niels, Jensen, Bo Amdi, Helleberg, Carsten, Plesner, Torben, Salomo, Morten, Svirskaite, Asta, Delarue, Richard, Moreau, Philippe, Blau, Igor, Goldschmidt, Hartmut, Schieferdecker, Aneta, Teleanu, Veronica, Munder, Markus, Röllig, Christoph, Salwender, Han-Juergen, Fuhrmann, Stephan, Weisel, Katja, Duerig, Jan, Zeis, Matthias, Klein, Stefan, Reimer, Peter, Schmidt, Christian, Scheid, Christof, Mayer, Karin, Hoffmann, Martin, Sosada, Markus, Dimopoulos, Athanasios, Delimpasi, Sosana, Kyrtsonis, Mary-Christine, Anagnostopoulos, Achilleas, Nagy, Zsolt, Illés, Árpád, Egyed, Miklós, Borbényi, Zita, Mikala, Gabor, Dally, Najib, Horowitz, Netanel, Gutwein, Odit, Nemets, Anatoly, Vaxman, Iuliana, Shvetz, Olga, Trestman, Svetlana, Ruchlemer, Rosa, Nagler, Arnon, Tadmor, Tamar, Rouvio, Ory, Preis, Meir, Gay, Francesca, Cavo, Michele, De Rosa, Luca, Musto, Pellegrino, Cafro, Anna, Tosi, Patrizia, Offidani, Massimo, Corso, Alessandro, Rossi, Giuseppe, Liberati, Anna Marina, Bosi, Alberto, Suzuki, Kenshi, Iida, Shinsuke, Nakaseko, Chiaki, Ishikawa, Takayuki, Matsumoto, Morio, Nagai, Hirokazu, Sunami, Kazutaka, Chou, Takaaki, Akashi, Koichi, Takezako, Naoki, Hagiwara, Shotaro, Eom, Hyeon Seok, Jo, Deog-Yeon, Kim, Jin Seok, Lee, Jae Hoon, Min, Chang Ki, Yoon, Sung Soo, Yoon, Dok Hyun, Kim, Kihyun, Zweegman, Sonja, Levin, Mark-David, Vellenga, Edo, Minnema, Monique, Schjesvold, Fredrik, Waage, Anders, Haukås, Einar, Grosicki, Sebastian, Pluta, Andrzej, Robak, Tadeusz, Marques, Herlander, Bergantim, Rui, Campilho, Fernando, Chng, Wee Joo, Goh, Yeow Tee, McDonald, Andrew, Rapoport, Bernado, Álvarez Rivas, Miguel Angel, De Arriba de La Fuente, Felipe, González Montes, Yolanda, Martin Sanchez, Jesus, Mateos, Maria Victoria, Oriol Rocafiguera, Albert, Rosinol, Laura, San Miguel, Jesús, Pérez de Oteyza, Jaime, Encinas, Cristina, Alegre-Amor, Adrian, López-Guía, Ana, Axelsson, Per, Carlson, Kristina, Stromberg, Olga, Hansson, Markus, Hveding Blimark, Cecile, Mueller, Rouven, Chen, Chih-Cheng, Liu, Ta-Chih, Huang, Shang-Yi, Wang, Po-Nan, Na Nakorn, Thanyaphong, Prayongratana, Kannadit, Beksac, Meral, Unal, Ali, Goker, Hakan, Sonmez, Mehmet, Korenkova, Sybiryna, Chaidos, Aristeidis, Oakervee, Heather, Sati, Hamdi, Benjamin, Reuben, Wechalekar, Ashutosh, Garg, Mamta, Kaiser, Martin, Ramasamy, Karthik, Cook, Gordon, Chantry, Andrew, Jenner, Matthew, Buadi, Francis, Berryman, Robert, Janakiram, Murali, Dimopoulos, Meletios A, Weisel, Katja Christina, Pluta, Agnieszka, Chng, Wee-Joo, Mateos, Maria-Victoria, Morgan, Gareth, Suryanarayan, Kaveri, Teng, Zhaoyang, Skacel, Tomas, Palumbo, Antonio, Dash, Ajeeta B, Gupta, Neeraj, Labotka, Richard, Rajkumar, S Vincent

Source: In The Lancet 19-25 January 2019 393(10168):253-264

A real‐world retrospective–prospective analysis of efficacy and safety of combined ixazomib, lenalidomide, and dexamethasone in relapsed/refractory multiple myeloma: The northern Italy experience.

Authors: Furlan, Anna, Cea, Michele, Pavan, Laura, Galli, Monica, Clissa, Cristina, Mangiacavalli, Silvia, Cafro, Anna Maria, Girlanda, Stefania, Patriarca, Francesca, Minotto, Claudia, Bertoldero, Giovanni, Barilà, Gregorio, Pascarella, Anna, Lico, Albana, Paolini, Rossella, Rabassi, Nicholas, Pescosta, Norbert, Porrazzo, Marika, De Sabbata, Giovanni, Pompa, Alessandra

Source: Cancer Medicine; Apr2024, Vol. 13 Issue 7, p1-14, 14p

Subject Terms: MULTIPLE myeloma, LENALIDOMIDE, DEXAMETHASONE, PERIPHERAL neuropathy, EXANTHEMA

Geographic Terms: NORTHERN Italy, ITALY

Safety and efficacy of pomalidomide plus low-dose dexamethasone in STRATUS (MM-010): a phase 3b study in refractory multiple myeloma

Authors: Dimopoulos, Meletios A., Palumbo, Antonio, Corradini, Paolo, Cavo, Michele, Delforge, Michel, Di Raimondo, Francesco, Weisel, Katja C., Oriol, Albert, Hansson, Markus, Vacca, Angelo, Blanchard, María Jesús, Goldschmidt, Hartmut, Doyen, Chantal, Kaiser, Martin, Petrini, Mario, Anttila, Pekka, Cafro, Anna Maria, Raymakers, Reinier, San-Miguel, Jesus, de Arriba, Felipe, Knop, Stefan, Röllig, Christoph, Ocio, Enrique M., Morgan, Gareth, Miller, Neil, Simcock, Mathew, Peluso, Teresa, Herring, Jennifer, Sternas, Lars, Zaki, Mohamed H., Moreau, Philippe

Source: In Blood 28 July 2016 128(4):497-503

Impact of the Addition of Daratumumab to the Standard Bortezomib-Thalidomide-Dexamethasone Regimen on Hematopoietic Stem Cell Mobilization and Collection, Post-Transplant Engraftment and Infectious Complications: A Case-Control Multicentre Real-Life Analysis

Authors: Cavallaro, Gianluca, Paris, Laura, Stefanoni, Paola, Pavoni, Chiara, Mangiacavalli, Silvia, Cartia, Claudio Salvatore, Pompa, Alessandra, Cafro, Anna Maria, Luisa Pioltelli, Maria, Pezzatti, Sara, Crippa, Stefano, Rambaldi, Alessandro, Galli, Monica

Source: Mediterranean Journal of Hematology & Infectious Diseases; 2024, Vol. 16 Issue 1, p1-4, 4p

Subject Terms: GRANULOCYTE-colony stimulating factor, PLASMA cells, HEMATOPOIETIC stem cells, REFERENCE values, AUTOGRAFTS, STEM cell transplantation

Dedalo: Phase II Study of Daratumumab Plus Pomalidomide and Dexamethasone (DPd) in Patients with Relapsed/Refractory Multiple Myeloma and 17p Deletion

Authors: Montefusco, Vittorio ^*, Cafro, Anna Maria ^*, Margiotta Casaluci, Gloria ^*, Patriarca, Francesca ^*, Mina, Roberto ^*, D'Agostino, Mattia ^*, Capra, Andrea ^*, Priola, Claudia ^*, Dalla Palma, Anna Benedetta ^*, Rizzi, Rita ^*, Genua, Angelo ^*, Petrucci, Maria Teresa, Paris, Laura ^*, Belotti, Angelo ^*, Cavo, Michele ^*, Conticello, Concetta ^*, Carlo-Stella, Carmelo, Boccadoro, Mario ^*

Source: In Blood 15 November 2022 140 Supplement 1:10193-10195

Aspirin or enoxaparin thromboprophylaxis for patients with newly diagnosed multiple myeloma treated with lenalidomide

Authors: Larocca, Alessandra, Cavallo, Federica, Bringhen, Sara, Di Raimondo, Francesco, Falanga, Anna, Evangelista, Andrea, Cavalli, Maide, Stanevsky, Anfisa, Corradini, Paolo, Pezzatti, Sara, Patriarca, Francesca, Cavo, Michele, Peccatori, Jacopo, Catalano, Lucio, Carella, Angelo Michele, Cafro, Anna Maria, Siniscalchi, Agostina, Crippa, Claudia, Petrucci, Maria Teresa, Yehuda, Dina Ben, Beggiato, Eloise, Di Toritto, Tommaso Caravita, Boccadoro, Mario, Nagler, Arnon, Palumbo, Antonio ^*

Source: In Blood 26 January 2012 119(4):933-939

Twice daily fludarabine/Ara-C associated to idarubicin, G-CSF and ATRA is an effective salvage regimen in non-promyelocytic acute myeloid leukemia

Authors: Montillo, Marco, Ricci, Francesca, Tedeschi, Alessandra, Cafro, Anna Maria, Nosari, Anna Maria, Nichelatti, Michele, Marbello, Laura, Morra, Enrica

Source: In Leukemia Research 2009 33(8):1072-1078

Osteonecrosis of the Jaw in Patients with Multiple Myeloma Treated with Bisphosphonates: Definition and Management of the Risk Related to Zoledronic Acid

Authors: Cafro, Anna Maria, Barbarano, Luciana, Nosari, Anna Maria, D'Avanzo, Giovanna, Nichelatti, Michele, Bibas, Michele, Gaglioti, Domenico, Taroni, Alberto, Riva, Francesco, Andriani, Alessandro

Source: In Clinical Lymphoma & Myeloma April 2008 8(2):111-116

Consolidation Treatment with VRD Followed By Maintenance Therapy Versus Maintenance Alone in Newly Diagnosed, Transplant-Eligible Patients with Multiple Myeloma (MM): A Randomized Phase 3 Trial of the European Myeloma Network (EMN02/HO95)

Authors: Sonneveld, Pieter, Beksac, Meral ^*, Van Der Holt, Bronno ^*, Dimopoulos, Meletios A, Carella, Angelo Michele ^*, Ludwig, Heinz, Zweegman, Sonja, Zander, Thilo ^*, Wester, Ruth ^*, Hajek, Roman, Pantani, Lucia ^*, Dozza, Luca ^*, Gay, Francesca, Cafro, Anna Maria ^*, De Rosa, Luca ^*, Fioritoni, Francesca ^*, Mellqvist, Ulf-Henrik, Troia, Rossella ^*, Andersen, Niels Frost ^*, Wu, Ka Lung, Driessen, Christoph, Carvalho, Susana ^*, Croockewit, Alexandra J. ^*, Schjesvold, Fredrik, Offidani, Massimo, Cavo, Michele ^*, Boccadoro, Mario

Source: In Blood 5 November 2020 136 Supplement 1:46-48

Preclinical discovery and initial clinical data of WVT078, a BCMA × CD3 bispecific antibody

Authors: Raab, Marc S., Cohen, Yael C., Schjesvold, Fredrik, Aardalen, Kimberly, Oka, Adwait, Spencer, Andrew, Wermke, Martin, Souza, Anita D., Kaufman, Jonathan L., Cafro, Anna Maria, Ocio, Enrique M., Doki, Noriko, Henson, Kristin, Trabucco, Gina, Carrion, Ana, Bender, Florent C., Juif, Pierre-Eric, Fessehatsion, Adonai, Fan, Liqiong, Stonehouse, Jeffrey P., Blankenship, John W., Granda, Brian, De Vita, Serena, Lu, Haihui

Source: Leukemia; June 2023, Vol. 37 Issue: 6 p1349-1360, 12p

Carfilzomib-Lenalidomide-Dexamethasone (KRd) Vs. Lenalidomide-Dexamethasone (Rd) in Newly Diagnosed Fit or Intermediate-Fit Multiple Myeloma Patients Not Eligible for Autologous Stem-Cell Transplantation (Phase III EMN20 Trial): Analysis of Sustained Undetectable Minimal Residual Disease (MRD)

Authors: Bringhen, Sara, Antonioli, Elisabetta, Gamberi, Barbara, Bruno, Benedetto, Derudas, Daniele, Tosi, Patrizia, Fazio, Francesca, Mazza, Rita, Ronconi, Sonia, Corradini, Paolo, Lotti, Flavia, Cellini, Claudia, Falcone, Antonietta Pia, Galieni, Piero, Ria, Roberto, Belotti, Angelo, Mannina, Donato, Cafro, Anna Maria, Cangialosi, Clotilde, Vincelli, Iolanda Donatella, Lombardo, Alessandra, Larocca, Alessandra, Boccadoro, Mario, D'Agostino, Mattia

Source: In Blood 2 November 2023 142 Supplement 1:205-205

Salvage Autologous Stem Cell Transplant for the Treatment of First Relapse Multiple Myeloma: Evidence of Its Clinical Role from a Multicenter Italian Study

Authors: Mangiacavalli, Silvia, Derudas, Daniele, Belotti, Angelo, Zamagni, Elena, Paris, Laura, Pavone, Vincenzo, Mina, Roberto, Di Renzo, Nicola, Fazio, Francesca, Tarantini, Giuseppe, Pezzatti, Sara, Palumbo, Gaetano, Marcatti, Magda, Vincelli, Jolanda Donatella, Cafro, Anna Maria, Falcone, Antonietta Pia, Zambello, Renato, Conticello, Concetta, Mazza, Rita, Di Raimondo, Francesco, Pompa, Alessandra, Martino, Enrica Antonia, Morabito, Fortunato, Stefanoni, Paola, Barila, Gregorio, Farina, Francesca, Cartia, Claudio Salvatore, Casson, Andrea, Ferretti, Virginia, Fresi, Eleonora, Arcaini, Luca, Petrucci, Maria Teresa, Gentile, Massimo

Source: In Blood 2 November 2023 142 Supplement 1:2226-2226

Initial Results from a Phase 1 Dose-Escalation Study of WVT078, a BCMA×CD3 Bispecific Antibody, in Combination with WHG626, a Gamma-Secretase (GS) Inhibitor, in Patients with Relapsed and/or Refractory Multiple Myeloma

Authors: Schjesvold, Fredrik, Spencer, Andrew, Cohen, Yael C., Ocio, Enrique M, López-Pardo, Jordi, Cafro, Anna Maria, Callander, Natalie S., Kaufman, Jonathan L., Mohan, Meera, Wermke, Martin, Doki, Noriko, Kan, Rebecca, Kulec, Karolina, Trabucco, Gina, Ye, Stan, Sechaud, Romain, Quadt, Cornelia, Chawla, Raghav, Raab, Marc S.

Source: In Blood 2 November 2023 142 Supplement 1:4752-4752

Impact of the Addition of Daratumumab to the Standard Bortezomib-Thalidomide-Dexamethasone Regimen on Hematopoietic Stem Cell Mobilization and Collection, Post-Transplant Engraftment and Infectious Complications: A Case-Control Multicentre Real-Life Analysis

Authors: Cavallaro, Gianluca, Galli, Monica, Paris, Laura, Stefanoni, Paola, Pavoni, Chiara, Mangiacavalli, Silvia, Masoni, Valeria, Palumbo, Michele, Pompa, Alessandra, Cafro, Anna Maria, Pezzatti, Sara, Crippa, Stefano, Rambaldi, Alessandro

Source: In Blood 2 November 2023 142 Supplement 1:4706-4706

OAB-004: Carfilzomib-based induction/consolidation with or without autologous transplant and Lenalidomide (R) or Carfilzomib-Lenalidomide (KR) maintenance: efficacy in high-risk patients of the FORTE study

Authors: Mina, Roberto, Zamagni, Elena, Rota-Scalabrini, Delia, Corradini, Paolo, Grasso, Mariella, Ballanti, Stelvio, Giuliani, Nicola, Rosa, Luca De, Cellini, Claudia, Vincelli, Iolanda Donatella, Velluti, Cristina, Capra, Andrea, Cafro, Anna Maria, Gozzetti, Alessandro, Gentile, Massimo, Aquino, Sara, Palmas, Angelo, Ledda, Antonio, Petrucci, Maria Teresa, Musto, Pellegrino, Boccadoro, Mario, Gay, Francesca

Source: Clinical lymphoma, myeloma & leukemia. 21(S2):S3-S3

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147759801.0x000001&indx=1&recIds=ETOCvdc_100147759801.0x000001

Myeloma's multiple morphologies.

Authors: Cantoni, Silvia, Galitzia, Andrea, Mancini, Valentina, Cafro, Anna Maria, Cairoli, Roberto

Source: EJHaem; Feb2024, Vol. 5 Issue 1, p260-261, 2p

Real-World Patterns of Utilization and Outcome of Market Approved Lenalidomide-Based Triplet Combinations in First Relapsed Multiple Myeloma Patients: Evidence from a Propensity Score Matched Analysis

Authors: Mangiacavalli, Silvia, Galli, Monica, Pezzatti, Sara, Belotti, Angelo, Fazio, Francesca, Marcatti, Magda, Cafro, Anna Maria, Mina, Roberto, Zambello, Renato, Paris, Laura, Cartia, Claudio Salvatore, Barilà, Gregorio, Olivares, Cecilia, Pompa, Alessandra, Mazza, Rita, Farina, Francesca, Soldarini, Martina, Benvenuti, Pietro, Lecci, Marica, Ferretti, Virginia Valeria, Petrucci, Maria Teresa

Source: In Blood 23 November 2021 138 Supplement 1:4109-4109