Reduction of tumor burden via precise photothermal release of sirolimus by carbon nanodots in 3D plexiform neurofibroma-in-a-dish models

Authors: Macchiaiolo, Marina ^{a, 1}, Cillari, Roberta ^{b, 1}, Gonfiantini, Michaela V. ^a, Cacchione, Antonella ^c, Mastronuzzi, Angela ^c, Cavallaro, Gennara ^b, Vecchio, Davide ^{a, ⁎}, Mauro, Nicolò ^{b, ⁎}

Source: In Surfaces and Interfaces 15 February 2025 59

Posterior fossa ependymoma in neurodevelopmental syndrome caused by a de novo germline pathogenic POLR2A variant

Authors: Paparella, Roberto, Caroleo, Anna Maria, Agolini, Emanuele, Chillemi, Giovanni, Miele, Evelina, Pedace, Lucia, Rinelli, Martina, Pizzi, Simone, Boccuto, Luigi, Colafati, Giovanna Stefania, Lodi, Mariachiara, Cacchione, Antonella, Carai, Andrea, Digilio, Maria Cristina, Tomà, Paolo, Tartaglia, Marco, Mastronuzzi, Angela

Source: American journal of medical genetics.Part A. 188(9):2796-2802

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100166441792.0x000001&indx=1&recIds=ETOCvdc_100166441792.0x000001

Expansion of the clinical and molecular spectrum of an XPD‐related disorder linked to biallelic mutations in ERCC2 gene

Authors: Agolini, Emanuele, Botta, Elena, Lodi, Mariachiara, Digilio, Maria Cristina, Rinelli, Martina, Bellacchio, Emanuele, Alesi, Viola, Nardo, Tiziana, Zambruno, Giovanna, Orioli, Donata, Alessi, Iside, Boccuto, Luigi, Rossi, Sabrina, Carai, Andrea, Colafati, Giovanna Stefania, Cacchione, Antonella, Dallapiccola, Bruno, Novelli, Antonio, Mastronuzzi, Angela

Source: Clinical genetics. 99(6):842-848

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121027353.0x000001&indx=1&recIds=ETOCvdc_100121027353.0x000001

ALK‐rearranged histiocytosis: Report of two cases with involvement of the central nervous system

Authors: Rossi, Sabrina, Gessi, Marco, Barresi, Sabina, Tamburrini, Gianpiero, Giovannoni, Isabella, Ruggiero, Antonio, Colafati, Giovanna Stefania, Frassanito, Paolo, Carboni, Alessia, Alexandre, Andrea, Cacchione, Antonella, Trombatore, Pietro, Diomedi‐Camassei, Francesca, Gaspari, Stefania, Gianno, Francesca, Marras, Carlo Efisio, Cecinati, Valerio, Carai, Andrea, Mastronuzzi, Angela, Alaggio, Rita

Source: Neuropathology & applied neurobiology. 47(6):878-881

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131519096.0x000001&indx=1&recIds=ETOCvdc_100131519096.0x000001

Upfront treatment with mTOR inhibitor everolimus in pediatric low‐grade gliomas: A single‐center experience

Authors: Cacchione, Antonella, Lodi, Mariachiara, Carai, Andrea, Miele, Evelina, Tartaglia, Marco, Megaro, Giacomina, Del Baldo, Giada, Alessi, Iside, Colafati, Giovanna Stefania, Carboni, Alessia, Boccuto, Luigi, Diomedi Camassei, Francesca, Catanzaro, Giuseppina, Po, Agnese, Ferretti, Elisabetta, Pedace, Lucia, Pizzi, Simone, Folgiero, Valentina, Pezzullo, Marco, Corsetti, Tiziana, Secco, Domitilla Elena, Cefalo, Maria Giuseppina, Locatelli, Franco, Mastronuzzi, Angela

Source: International journal of cancer. 148(10):2522-2534

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117554879.0x000001&indx=1&recIds=ETOCvdc_100117554879.0x000001

Pediatric brain tumor patients display altered immune activation and reduced lymphopoiesis at the onset of disease.

Authors: Rosichini, Marco, Del Baldo, Giada, De Luca, Carmen Dolores, Benini, Francesca, Genah, Shirley, Vinci, Maria, Cerimele, Alfredo, Coccetti, Marianna, Flamini, Sara, Carsetti, Rita, Cacchione, Antonella, Carai, Andrea, Mastronuzzi, Angela, Locatelli, Franco, Velardi, Enrico

Source: NPJ Precision Oncology; 11/20/2024, Vol. 8 Issue 1, p1-10, 10p

Subject Terms: CENTRAL nervous system diseases, CHILD patients, TUMOR growth, BRAIN tumors, IMMUNOLOGIC memory

The coexistence of a BRCA2 germline and a DICER1 somatic variant in two first-degree cousins suggests their potential synergic effect.

Authors: Del Baldo, Giada, Mastronuzzi, Angela, Cipri, Selene, Agolini, Emanuele, Matraxia, Marta, Novelli, Antonio, Cacchione, Antonella, Serra, Annalisa, Carai, Andrea, Boccuto, Luigi, Colafati, Giovanna Stefania, Di Paolo, Pier Luigi, Miele, Evelina, Barresi, Sabina, Alaggio, Rita, Rossi, Sabrina, Giovannoni, Isabella

Source: Scientific Reports; 9/13/2024, Vol. 14 Issue 1, p1-9, 9p

Machine Learning Analysis in Diffusion Kurtosis Imaging for Discriminating Pediatric Posterior Fossa Tumors: A Repeatability and Accuracy Pilot Study.

Authors: Voicu, Ioan Paul, Dotta, Francesco, Napolitano, Antonio, Caulo, Massimo, Piccirilli, Eleonora, D'Orazio, Claudia, Carai, Andrea, Miele, Evelina, Vinci, Maria, Rossi, Sabrina, Cacchione, Antonella, Vennarini, Sabina, Del Baldo, Giada, Mastronuzzi, Angela, Tomà, Paolo, Colafati, Giovanna Stefania

Source: Cancers; Jul2024, Vol. 16 Issue 14, p2578, 16p

Subject Terms: RANDOM forest algorithms, GLIOMAS, PILOT projects, MAGNETIC resonance imaging, INFRATENTORIAL brain tumors, RETROSPECTIVE studies, DESCRIPTIVE statistics, PEDIATRICS, RESEARCH bias, MACHINE learning, CANCER patient psychology, COMPARATIVE studies

Paediatric astroblastoma‐like neuroepithelial tumour of the spinal cord with a MAMLD1‐BEND2 rearrangement

Authors: Rossi, Sabrina, Barresi, Sabina, Colafati, Giovanna Stefania, Giovannoni, Isabella, Miele, Evelina, Alesi, Viola, Cacchione, Antonella, Diomedi‐Camassei, Francesca, Macari, Gabriele, Antonelli, Manila, Carboni, Alessia, Carai, Andrea, Mastronuzzi, Angela, Giangaspero, Felice, Gessi, Marco, Alaggio, Rita

Source: Neuropathology & applied neurobiology. 48(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154993988.0x000001&indx=1&recIds=ETOCvdc_100154993988.0x000001

Robot-Assisted Stereotactic Biopsy of Diffuse Intrinsic Pontine Glioma: A Single-Center Experience

Authors: Carai, Andrea, Mastronuzzi, Angela, De Benedictis, Alessandro, Messina, Raffaella, Cacchione, Antonella, Miele, Evelina, Randi, Franco, Esposito, Giacomo, Trezza, Andrea, Colafati, Giovanna Stefania, Savioli, Alessandra, Locatelli, Franco, Marras, Carlo Efisio

Source: In World Neurosurgery May 2017 101:584-588

A second case report of medulloblastoma in a patient carrying biallelic pathogenic MUTYH germline variants.

Authors: Cipri, Selene, Del Baldo, Giada, Carai, Andrea, Cacchione, Antonella, Agolini, Emanuele, Novelli, Antonio, Rossi, Sabrina, Colafati, Giovanna Stefania, Boccuto, Luigi, Mastronuzzi, Angela

Source: Neuropathology & Applied Neurobiology; Apr2024, Vol. 50 Issue 2, p1-4, 4p

Subject Terms: RECESSIVE genes, GERM cells, MEDULLOBLASTOMA, BRCA genes, CANCER genetics, INFORMED consent (Medical law), MEDICAL genetics

Malignant peripheral nerve sheath tumor (MPNST) and MPNST-like entities are defined by a specific DNA methylation profile in pediatric and juvenile population.

Authors: Patrizi, Sara, Miele, Evelina, Falcone, Lorenza, Vallese, Silvia, Rossi, Sabrina, Barresi, Sabina, Giovannoni, Isabella, Pedace, Lucia, Nardini, Claudia, Masier, Ilaria, Abballe, Luana, Cacchione, Antonella, Russo, Ida, Di Giannatale, Angela, Di Ruscio, Valentina, Salgado, Claudia Maria, Mastronuzzi, Angela, Ciolfi, Andrea, Tartaglia, Marco, Milano, Giuseppe Maria

Source: Clinical Epigenetics; 1/4/2024, Vol. 16 Issue 1, p1-12, 12p

Subject Terms: SCHWANNOMAS, DNA methylation, CHILD patients

Expanding the spectrum of EWSR1‐PATZ1 rearranged CNS tumors: An infantile case with leptomeningeal dissemination

Authors: Rossi, Sabrina, Barresi, Sabina, Giovannoni, Isabella, Alesi, Viola, Ciolfi, Andrea, Colafati, Giovanna Stefania, Diomedi‐Camassei, Francesca, Miele, Evelina, Cacchione, Antonella, Quacquarini, Denise, Carai, Andrea, Tartaglia, Marco, Giannini, Caterina, Giangaspero, Felice, Mastronuzzi, Angela, Alaggio, Rita

Source: Brain pathology. 31(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123059991.0x000001&indx=1&recIds=ETOCvdc_100123059991.0x000001

Pediatric spinal glioblastoma of the conus medullaris: a case report of long survival

Authors: Cacchione, Antonella, Mastronuzzi, Angela, Cefalo, Maria Giuseppina, Colafati, Giovanna Stefania, Diomedi‐Camassei, Francesca, Rizzi, Michele, De Benedictis, Alessandro, Carai, Andrea

Source: Cancer communications. 35(1):1-4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100098196970.0x000001&indx=1&recIds=ETOCvdc_100098196970.0x000001

Unraveling the impact of upfront chemotherapy and proton beam therapy on treatment outcome and follow-up in central nervous system germ cell tumors: a single center experience.

Authors: Del Baldo, Giada, Vennarini, Sabina, Toniutti, Maristella, Abbas, Rachid, Lorentini, Stefano, Piccirilli, Eleonora, Cacchione, Antonella, Megaro, Giacomina, Di Ruscio, Valentina, De Ioris, Maria Antonietta, De Salvo, Andrea, Albino, Giulia, Rossi, Sabrina, Colafati, Giovanna Stefania, Carai, Andrea, Mastronuzzi, Angela

Source: Frontiers in Oncology; 2023, p1-12, 12p

Subject Terms: GERM cell tumors, PROTON therapy, CENTRAL nervous system, TREATMENT effectiveness, RADIATION carcinogenesis, RADIATION injuries, YOUNG adults

SHH medulloblastoma and very early onset of bowel polyps in a child with PTEN hamartoma tumor syndrome.

Authors: Maria Caroleo, Anna, Rotulo, Silvia, Agolini, Emanuele, Macchiaiolo, Marina, Boccuto, Luigi, Antonelli, Manila, Colafati, Giovanna Stefania, Cacchione, Antonella, Megaro, Giacomina, Carai, Andrea, De Ioris, Maria Antonietta, Lodi, Mariachiara, Tornesello, Assunta, Simone, Valeria, Torroni, Filippo, Cinalli, Giuseppe, Mastronuzzi, Angela

Source: Frontiers in Molecular Neuroscience; 2023, p1-7, 7p

Subject Terms: TUMOR suppressor genes, INFANTS, HAMARTOMA, PTEN protein, MEDULLOBLASTOMA, POLYPS

Extra-neural metastases in pediatric diffuse midline gliomas, H3 K27-altered: presentation of two cases and literature review.

Authors: De Martino, Lucia, Picariello, Stefania, Russo, Carmela, Errico, Maria Elena, Spennato, Pietro, Papa, Maria Rosaria, Normanno, Nicola, Scimone, Giuseppe, Colafati, Giovanna Stefania, Cacchione, Antonella, Mastronuzzi, Angela, Massimino, Maura, Cinalli, Giuseppe, Quaglietta, Lucia

Source: Frontiers in Molecular Neuroscience; 2023, p1-12, 12p

Subject Terms: GLIOMAS, METASTASIS, PLEURAL effusions, CHILD patients, ILIUM

Diagnostic and Dosimetry Features of [⁶⁴Cu]CuCl2 in High-Grade Paediatric Infiltrative Gliomas.

Authors: Fiz, Francesco, Bottoni, Gianluca, Ugolini, Martina, Righi, Sergio, Cirone, Alessio, Garganese, Maria Carmen, Verrico, Antonio, Rossi, Andrea, Milanaccio, Claudia, Ramaglia, Antonia, Mastronuzzi, Angela, Abate, Massimo Eraldo, Cacchione, Antonella, Gandolfo, Carlo, Colafati, Giovanna Stefania, Garrè, Maria Luisa, Morana, Giovanni, Piccardo, Arnoldo

Source: Molecular Imaging & Biology; Apr2023, Vol. 25 Issue 2, p391-400, 10p

Subject Terms: COPPER, GLIOMA treatment, TUMOR diagnosis, RADIATION dosimetry, RADIOPHARMACEUTICALS, ALGORITHMS

Editorial: Pediatric diencephalic tumors: a constellation of entities and management modalities.

Authors: Cacchione, Antonella, Carai, Andrea, Biassoni, Veronica, Mastronuzzi, Angela, Vennarini, Sabina

Source: Frontiers in Oncology; 2023, p01-03, 3p

Subject Terms: ONCOLOGY, TUMORS, BRAIN tumors

The peculiar challenge of bringing CAR-T cells into the brain: Perspectives in the clinical application to the treatment of pediatric central nervous system tumors.

Authors: Del Baldo, Giada, Del Bufalo, Francesca, Pinacchio, Claudia, Carai, Andrea, Quintarelli, Concetta, De Angelis, Biagio, Merli, Pietro, Cacchione, Antonella, Locatelli, Franco, Mastronuzzi, Angela

Source: Frontiers in Immunology; 3/21/2023, Vol. 14, p1-12, 12p

Subject Terms: CENTRAL nervous system tumors, BRAIN tumors, PEDIATRIC therapy, CLINICAL medicine, THERAPEUTICS, CHILD patients