The role of tumor-associated macrophages in gastric cancer development and their potential as a therapeutic target

Authors: Gambardella, V., Castillo, J., Tarazona, N., Gimeno-Valiente, F., Martínez-Ciarpaglini, C., Cabeza-Segura, M., Roselló, S., Roda, D., Huerta, M., Cervantes, A., Fleitas, T.

Source: In Cancer Treatment Reviews June 2020 86

638PDevelopment of a living organoid biobank derived from colorectal cancer patients: Towards personalized medicine

Authors: Papaccio, F, Gutierrez-Bravo, M F, Cabeza-Segura, M, Gambardella, V, Huerta, M, Ciarpaglini, C Martinez, Keranen, S Rosello, Gimeno-Valiente, F, Fleitas, T, Llavero, N Tarazona, Roda, D, Cervantes, A, Castillo, J

Source: Annals of oncology. 30(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097990413.0x000001&indx=1&recIds=ETOCvdc_100097990413.0x000001

64P Integrative immune transcriptomic classification could improve patient selection for precision immunotherapy in advanced gastroesophageal adenocarcinoma

Authors: Cabeza Segura, M., Gambardella, V., Gimeno-Valiente, F., Carbonell-Asins, J.A., Alarcon-Molero, L., Gonzalez-Vilanova, A., Zuniga-Trejos, S., Rentero-Garrido, P., Villagrasa, R., Gil Raga, M., Richart, P., Huerta, M., Rosello Keranen, S., Roda Perez, D., Tarazona Llavero, N., Martínez-Ciarpaglini, C., Castillo, J., Cervantes, A., Fleitas, T.C.

Source: In Annals of Oncology October 2022 33 Supplement 8:S1402-S1403

379P Whole exome sequencing of plasma circulating tumor DNA identifies dynamic mutational changes to guide targeted therapies in colon cancer patients

Authors: Martín-Arana, J., Gimeno-Valiente, F., Tébar-Martínez, R., García-Mico, B., Gambardella, V., Huerta, M., Martínez-Ciarpaglini, C., Carbonell-Asins, J.A., Cabeza Segura, M., Martín-Arévalo, J., Casado, D., Pla, V., Pérez, L., Rentero-Garrido, P., Rosello Keranen, S., Fleitas, T.C., Castillo, J., Roda Perez, D., Cervantes, A., Tarazona Llavero, N.

Source: In Annals of Oncology September 2022 33 Supplement 7:S709-S709

360P Epigenetic engineering on CDX2 allows to determine the interplaying consequences with other genetic and transcriptomic events in colorectal cancer

Authors: Gimeno-Valiente, F., Duréndez, E., Badía, J., Martínez-Ciarpaglini, C., Iglesias, M., Linares, J.L., Huerta, M., Moro, D., Gambardella, V., Martín-Arana, J., Fleitas, T.C., Roselló Keränen, S., Cabeza Segura, M., García-Mico, B., Rentero-Garrido, P., Roda, D., Castillo, J., Cervantes, A., Calon, A., Tarazona Llavero, N.

Source: In Annals of Oncology September 2022 33 Supplement 7:S700-S700

In the literature: December 2021

Authors: Montagut, C., Gambardella, V., Cabeza-Segura, M., Fleitas, T., Cervantes, A.

Source: In ESMO Open February 2022 7(1)

1432P Characterizing diversity in the immune profile by a transcriptomic customized gene signature to potentially personalize treatment in advanced gastric cancer patients

Authors: Cabeza-Segura, M., Alarcón-Molero, L., Gambardella, V., Carbonell-Asins, J.A., Zuñiga, S., Gimeno-Valiente, F., Garzón-Lloría, Z., Gil Raga, M., Durá, A., Richart, P., Alonso, N., Villagrasa, R., Alfaro-Cervello, C., Peña, A., Huerta Alvaro, M., Tarazona, N., Martínez-Ciarpaglini, C., Cervantes, A., Castillo, J., Fleitas, T.

Source: In Annals of Oncology September 2021 32 Supplement 5:S1070-S1071

464P Exome sequencing of ctDNA portrays the mutational landscape of patients with relapsing colon cancer and indicates new actionable targets

Authors: Tarazona, N., Martín-Arana, J., Tébar-Martínez, R., Gimeno-Valiente, F., Gambardella, V., Alvaro, M. Huerta, Martínez-Ciarpaglini, C., Alfaro-Cervello, C., Cabeza-Segura, M., García-Micó, B., Moragón, S., Tapia, M., Carbonell-Asins, J.A., Rentero-Garrido, P., Zuñiga, S., Roselló, S., Fleitas, T., Castillo, J., Perez, D. Roda, Cervantes, A.

Source: In Annals of Oncology September 2021 32 Supplement 5:S564-S564

490P Metastatic colorectal cancer derived organoids recapitulate genomic profile and treatment response of the original tumor

Authors: Papaccio, F., Bravo, M.F. Gutierrez, Cabeza-Segura, M., Gimeno-Valiente, F., Gambardella, V., Garzón-Lloría, Z., García-Micó, B., Huerta, M., Martínez-Ciarpaglini, C., Alfaro-Cervello, C., Sabater, L., Lombardi, P., Rentero-Garrido, P., Zúñiga-Trejos, S., Keränen, S. Roselló, Fleitas, T., Tarazona, N., Roda, D., Cervantes, A., Castillo, J.

Source: In Annals of Oncology September 2020 31 Supplement 4:S449-S449

53P - ZNF518B as a transcriptional factor involved in colorectal cancer progression through the epithelial to mesenchymal transition

Authors: Valiente, F.G., Tarazona, N., Gambardella, V., Riffo-Campos, Á, Papaccio, F., Cabeza-Segura, M., López-Rodas, G., Cervantes, A., Franco, L., Castillo, J.

Source: In Annals of Oncology November 2019 30 Supplement 7:vii16-vii16

28P - CNAs concordance between CRC-PDOs and the original tissue reveals relevant oncogenic pathways alterations

Authors: Castillo, J., Papaccio, F., Valiente, F.G., Gutierrez-Bravo, M.F., Cabeza-Segura, M., Gambardella, V., Huerta, M.D.S., Martinez-Ciarpaglini, C., Alfaro-Cervello, C., Rentero-Garrido, P., Zúñiga-Trejos, S., Rosello Keranen, S., Fleitas, T., Tarazona, N., Roda Perez, D., Cervantes, A.

Source: In Annals of Oncology November 2019 30 Supplement 7:vii9-vii9

638P - Development of a living organoid biobank derived from colorectal cancer patients: Towards personalized medicine

Authors: Papaccio, F., Gutierrez-Bravo, M.F., Cabeza-Segura, M., Gambardella, V., Huerta, M., Ciarpaglini, C Martinez, Keranen, S Rosello, Gimeno-Valiente, F., Fleitas, T., Llavero, N Tarazona, Roda, D., Cervantes, A., Castillo, J.

Source: In Annals of Oncology October 2019 30 Supplement 5:v240-v241