Discovery of Novel Antifungal Agents from Polygonatum odoratum Targeting 14-Alpha Demethylase Enzyme for the Treatment of Black Fungus (Mucormycosis)

Authors: Begum, Aqsa, Ameen, Nagar, Sanjay Shrinivas, Upendra, R S, Karthik, R

Source: 2024 International Conference on Intelligent Systems and Advanced Applications (ICISAA) Intelligent Systems and Advanced Applications (ICISAA), 2024 International Conference on. :1-5 Oct, 2024

Relation: 2024 International Conference on Intelligent Systems and Advanced Applications (ICISAA)

Bibliometric Analysis using Cytochrome P450 (CYP51) Data Between 1980–2018 for BigData and Blockchain in Biomedical Research

Authors: Jamal, Arshad, Muzakkin, Dewi Vera Martika, Fatima, Mariam-Aisha, Helmi, Rabab Alayham Abbas, Mustapha, Safinaz Binti

Source: 2023 IEEE 14th Control and System Graduate Research Colloquium (ICSGRC) Control and System Graduate Research Colloquium (ICSGRC), 2023 IEEE 14th. :144-148 Aug, 2023

Relation: 2023 IEEE 14th Control and System Graduate Research Colloquium (ICSGRC)

Improvement of Skin Lesions in an Adult with CHILD Syndrome Treated with 2% Ketoconazole Cream

Authors: Omi Michiya, Kana Tanahasi, Takuya Takeichi, Masashi Akiyama

Source: Acta Dermato-Venereologica, Vol 104 (2024)

Subject Terms: congenital hemidysplasia with ichthyosiform naevus and limb defects, cholesterol, CYP51, ichthyosis, squalene, Dermatology, RL1-803

File Description: electronic resource

Relation: https://medicaljournalssweden.se/actadv/article/view/41929; https://doaj.org/toc/0001-5555; https://doaj.org/toc/1651-2057

Access URL: https://doaj.org/article/62230ac7b91a43d0a521e26e26c7714d

Occurrence and dynamics of resistance to a QoI and a DMI fungicide in Erysiphe necator the causal agent of grape powdery mildew in Israel

Authors: Gur, L. ^{a, b, c, ⁎}, Cohen, Y. ^b, Frenkel, O. ^c, Ovadia, S. ^d, Reuveni, M. ^{a, ⁎⁎}

Source: In Crop Protection May 2025 191

Design, synthesis and bioactivity evaluation of triazole antifungal drugs with phenylthiophene structure

Authors: Wu, Xudong ^a, Zhang, Jiachen ^a, Liu, Rongrong ^a, Sun, Yixiang ^a, Gao, Zixuan ^a, Zhang, Guoqi ^a, Luo, Zirui ^a, Li, Kejian ^a, Qin, Qiaohua ^a, Liu, Nian ^a, Zhang, Haoyu ^a, Su, Xin ^b, Zhao, Dongmei ^{a, ⁎}, Cheng, Maosheng ^a

Source: In Bioorganic Chemistry December 2024 153

Heuristic analysis of structure, activity and selectivity relationships of isocoumarin derivatives as potential antifungal agents

Authors: Simić Milena, Erić Slavica

Source: Arhiv za farmaciju, Vol 74, Iss 6, Pp 796-808 (2024)

Subject Terms: isocoumarins, heuristic analysis, c albicans, cyp51, antifungals, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2024/0004-19632406796S.pdf; https://doaj.org/toc/0004-1963; https://doaj.org/toc/2217-8767

Access URL: https://doaj.org/article/da031c6ed9154d4287ddab5a01d7dd24

Shaping immune landscape of colorectal cancer by cholesterol metabolites

Authors: Yibing Bai, Tongzhou Li, Qinshu Wang, Weiqiang You, Haochen Yang, Xintian Xu, Ziyi Li, Yu Zhang, Chengsong Yan, Lei Yang, Jiaqian Qiu, Yuanhua Liu, Shiyang Chen, Dongfang Wang, Binlu Huang, Kexin Liu, Bao- Liang Song, Zhuozhong Wang, Kang Li, Xin Liu, Guangchuan Wang, Weiwei Yang, Jianfeng Chen, Pei Hao, Zemin Zhang, Zhigang Wang, Zheng-Jiang Zhu, Chenqi Xu

Source: EMBO Molecular Medicine, Vol 16, Iss 2, Pp 334-360 (2024)

Subject Terms: Colorectal Cancer with Microsatellite Stability, Asynchronous Cholesterol Biosynthesis, Distal Cholesterol Precursors, Th17, Cyp51 Targeted Therapy, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/a0b9d1b7b5d2433d90da1229130e43db

The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus

Authors: Parham Hosseini, Mikhail V. Keniya, Alia A. Sagatova, Stephanie Toepfer, Christoph Müller, Joel D. A. Tyndall, Anette Klinger, Edmond Fleischer, Brian C. Monk

Source: Journal of Fungi, Vol 10, Iss 12, p 820 (2024)

Subject Terms: Aspergillus fumigatus CYP51, ERG6, CPRA, eburicol, fluconazole, voriconazole, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2309-608X/10/12/820; https://doaj.org/toc/2309-608X

Access URL: https://doaj.org/article/7001f2668c7143aab0fb22f542db1f27

The Antifungal Effects of Berberine and Its Proposed Mechanism of Action Through CYP51 Inhibition, as Predicted by Molecular Docking and Binding Analysis

Authors: Chao-Wei Zhang, Dong-Yu Huang, Muhammad Shahid Riaz Rajoka, Yan Wu, Zhen-Dan He, Liang Ye, Yan Wang, Xun Song

Source: Molecules, Vol 29, Iss 21, p 5079 (2024)

Subject Terms: berberine, antifungal, Candida albicans, Cryptococcus neoformans, Trichophyton, CYP51 inhibition, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/21/5079; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/09515c3542f24d21be21b973ce4a0338

Synthesis of N-acylsulfonamide chromone derivatives as efficient anti-Candida albicans agents

Authors: Qiu, Yingqi ^a, Lu, Jiahao ^a, Zhao, Chenhao ^a, Xiang, Yuqiang ^a, Wu, Aiqun ^a, Shen, Liqun ^{a, ⁎}, Jiang, Haiou ^{b, ⁎}

Source: In Journal of Molecular Structure 5 July 2025 1334

Greenhouses represent an important evolutionary niche for Alternaria alternata

Authors: Guangzhu Yang, Sai Cui, Wenjing Huang, Shutong Wang, Jun Ma, Ying Zhang, Jianping Xu

Source: Microbiology Spectrum, Vol 12, Iss 6 (2024)

Subject Terms: fungal pathogen, Alternaria, fungicide tolerance, triazoles, population genetics, cyp51, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/e2c6afc3786f4117b6d58b1395328f9e

In silico targeting CYP51 of Naegleria fowleri using bioactive compounds from Indonesian plants

Authors: Nelson Daniel, Fisranda Ferdinand, Parikesit Arli Aditya

Source: Journal of Pharmacy & Pharmacognosy Research, Vol 11, Iss 5, Pp 841-862 (2023)

Subject Terms: bioactive compounds, cyp51, molecular docking, molecular dynamics, molecular simulation, naegleria fowleri, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://jppres.com/jppres/pdf/vol11/jppres23.1693_11.5.841.pdf; https://doaj.org/toc/0719-4250

Access URL: https://doaj.org/article/c5c0db0d9dd64f90ae1fc611a9f2711c

Harnessing Machine Learning to Uncover Hidden Patterns in Azole-Resistant CYP51/ERG11 Proteins

Authors: Otávio Guilherme Gonçalves de Almeida, Marcia Regina von Zeska Kress

Source: Microorganisms, Vol 12, Iss 8, p 1525 (2024)

Subject Terms: CYP51, ERG11, machine learning, azoles, fungal resistance, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/12/8/1525; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/b398c78c65514083aa0e66435ec07f21

Benzo[g]quinazolines as antifungal against candidiasis: Screening, molecular docking, and QSAR investigations

Authors: Hatem A. Abuelizz, Ahmed H. Bakheit, Mohamed H. Al-Agamy, Harunor Rashid, Gamal A.E. Mostafa, Rashad Al-Salahi

Source: Saudi Pharmaceutical Journal, Vol 31, Iss 6, Pp 815-823 (2023)

Subject Terms: Anticandidal agent, Benzo[g]quinazolines, Candida albicans, CYP51, Molecular docking, Quantitative structure–activity relationship, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1319016423000956; https://doaj.org/toc/1319-0164

Access URL: https://doaj.org/article/96360f0c163c478ca41919b18df3787b

Detection and characterization of difenoconazole resistance in Stagonosporopsis citrulli from watermelon and muskmelon in Zhejiang Province of China

Authors: Zhangliang Kong, Yu Zhang, Chaojie Zhuang, Chenxin Mao, Chuanqing Zhang

Source: Phytopathology Research, Vol 5, Iss 1, Pp 1-11 (2023)

Subject Terms: Watermelon, Muskmelon, Gummy stem blight, Fungicide resistance, Difenoconazole, cyp51, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://doaj.org/toc/2524-4167

Access URL: https://doaj.org/article/72454863eb794ce1ba28add0c93609a0

Design, synthesis and in vitro biological studies of novel triazoles with potent and broad-spectrum antifungal activity

Authors: Junhe Bao, Yumeng Hao, Tingjunhong Ni, Ruina Wang, Jiacun Liu, Xiaochen Chi, Ting Wang, Shichong Yu, Yongsheng Jin, Lan Yan, Xiaomei Li, Dazhi Zhang, Fei Xie

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)

Subject Terms: Triazole derivatives, antifungal activity, structure-activity relationships, Cyp51, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/ee80bcdd87cf43118a1df79552e16a0f

Design, synthesis and biological activity of hybrid antifungals derived from fluconazole and mebendazole

Authors: Ghobadi, Elham ^{a, b}, Hashemi, Seyedeh Mahdieh ^a, Fakhim, Hamed ^c, Hosseini-khah, Zahra ^d, Badali, Hamid ^{e, f}, Emami, Saeed ^{a, ∗}

Source: In European Journal of Medicinal Chemistry 5 March 2023 249

Status of Fungicide Resistance and Physiological Characterization of Tebuconazole Resistance in Rhizocotonia solani in Sichuan Province, China

Authors: Changwei Gong, Min Liu, Dan Liu, Qiulin Wang, Ali Hasnain, Xiaoxu Zhan, Jian Pu, Yueyang Liang, Xuemei Liu, Xuegui Wang

Source: Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 4859-4876 (2022)

Subject Terms: rice sheath blight, tebuconazole, epoxiconazole, CYP51 mutation, binding energy, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/44/10/330; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/9e5de2047f8a414b8a4f20fef018c80a

Fungicide Sensitivity Profile of Pyrenophora teres f. teres in Field Population

Authors: Regina Pütsepp, Andres Mäe, Lee Põllumaa, Liis Andresen, Riinu Kiiker

Source: Journal of Fungi, Vol 10, Iss 4, p 260 (2024)

Subject Terms: net blotch, fungicide sensitivity, CYP51, Cyp51A promoter, SDH subunits, Cyt b, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2309-608X/10/4/260; https://doaj.org/toc/2309-608X

Access URL: https://doaj.org/article/04c02ebc64fc476280ccac18ffb55934

Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads

Authors: W. David Nes, Minu Chaudhuri, David J. Leaver

Source: Biomolecules, Vol 14, Iss 3, p 249 (2024)

Subject Terms: ergosterol-dependent diseases, trypanosomes, fungi, irreversible enzyme inhibitors, sterol methyltransferase, CYP51, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/3/249; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/32268203d6b44c92945cf415e8ba7261