New Perspectives on the Impact of Iron Chelation Therapy on the Gut Microbiome in Thalassemia Patients.

Authors: Deumić, Sara¹ (AUTHOR) sara.deumic@ibu.edu.ba, Crnčević, Neira^1,2 (AUTHOR), Hukić, Mirsada^2,3 (AUTHOR), Dizdar, Muamer⁴ (AUTHOR), Avdić, Monia^1,2 (AUTHOR)

Source: Thalassemia Reports. Mar2025, Vol. 15 Issue 1, p2. 10p.

Subject Terms: *CHELATION therapy, *IRON overload, *GUT microbiome, *BLOOD transfusion, *MICROBIAL diversity, *DEFEROXAMINE, *FETAL hemoglobin

Early economic evaluation of chelation therapy in kidney transplant recipients with high-normal lead.

Authors: Hao, Jiasi¹ (AUTHOR) j.hao@umcg.nl, Alizadeh, Behrooz Z.¹ (AUTHOR), Postma, Maarten J.^2,3,4 (AUTHOR), Touw, Daan J.⁵ (AUTHOR), Bakker, Stephan J. L.⁶ (AUTHOR), de Jong, Lisa A.² (AUTHOR)

Source: PLoS ONE. 2/27/2025, Vol. 20 Issue 2, p1-23. 23p.

Subject Terms: *CHELATION therapy, *KIDNEY transplantation, *MARKOV processes, *SENSITIVITY analysis, *CHELATION

Beta‐Thalassemia Major and Myocardial Iron Overload: A Longitudinal Study with Magnetic Resonance Imaging.

Authors: Rezaei-Kalantari, Kiara¹ (AUTHOR), Meftah, Elahe² (AUTHOR), Tofighi, Saeed³ (AUTHOR), Khalaj, Kamand⁴ (AUTHOR), Zoroufian, Arezou³ (AUTHOR), Motevalli, Marzieh¹ (AUTHOR), Inusah Bihinaa, Mohammed⁴ (AUTHOR), Omidi, Negar⁵ (AUTHOR) negar.omidi@gmail.com, Ghorashi, Seyyed Mojtaba⁶ (AUTHOR), Luo, Zhiwen (AUTHOR)

Source: Cardiology Research & Practice. 7/24/2024, Vol. 2024, p1-9. 9p.

Subject Terms: *HEART metabolism, *CHELATION therapy, *FERRITIN, *IRON overload, *SCIENTIFIC observation, *MAGNETIC resonance imaging, *RETROSPECTIVE studies, *DESCRIPTIVE statistics, *LONGITUDINAL method, *VENTRICULAR dysfunction, *HEMATOPOIESIS, *INJECTIONS, *DEFEROXAMINE, *LIVER, *BLOOD transfusion, *BETA-Thalassemia, *PATIENT aftercare, *TIME

Copper Chelation Therapy Attenuates Periodontitis Inflammation through the Cuproptosis/Autophagy/Lysosome Axis.

Authors: Zhang, Lujin¹ (AUTHOR), Tsai, I-Chen¹ (AUTHOR), Ni, Zihan¹ (AUTHOR) zlujin@163.com, Chen, Beichen¹ (AUTHOR), Zhang, Shuaiyuan¹ (AUTHOR), Cai, Luhui¹ (AUTHOR), Xu, Qiong¹ (AUTHOR) xqiong@mail.sysu.edu.cn

Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5890. 20p.

Subject Terms: *LYSOSOMES, *CHELATION therapy, *PERIODONTITIS, *CATHEPSIN B, *AUTOPHAGY, *MEMBRANE permeability (Biology), *CHELATING agents

Challenges of Iron Chelation in Thalassemic Children.

Authors: Adramerina, Alkistis¹ (AUTHOR) alkistis_adrame@yahoo.com, Economou, Marina¹ (AUTHOR)

Source: Thalassemia Reports. Mar2024, Vol. 14 Issue 1, p1-9. 9p.

Subject Terms: *CHELATION, *CHELATION therapy, *IRON chelates, *IRON overload, *IRON

Pubertal Development in Girls with Beta Thalassaemia and Assessment of the Adequacy of Chelation Therapy: A Quasi-experimental Study.

Authors: MODAK, RUPALI¹, PAL, AMITAVA², DAS, SHUVENDU³, BISWAS, DILIP KUMAR⁴ drdkb75@gmail.com

Source: Journal of Clinical & Diagnostic Research. Mar2024, Vol. 18 Issue 3, p5-9. 5p.

Subject Terms: *BETA-Thalassemia, *CHELATION therapy, *HYPERFERRITINEMIA, *PRECOCIOUS puberty, *BODY mass index

Company/Entity: MICROSOFT Corp. 081466849 MSFT

Drug Selection and Posology, Optimal Therapies and Risk/Benefit Assessment in Medicine: The Paradigm of Iron-Chelating Drugs.

Authors: Kontoghiorghes, George J.¹ (AUTHOR) kontoghiorghes.g.j@pri.ac.cy

Source: International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16749. 30p.

Subject Terms: *DEFERASIROX, *CHELATION therapy, *DRUG dosage, *SICKLE cell anemia, *IRON, *STEM cell transplantation, *IRON fertilizers

Combination chelation therapy.

Authors: Aydinok, Yesim¹ (AUTHOR) yesim.aydinok@yahoo.com

Source: Annals of the New York Academy of Sciences. Nov2023, Vol. 1529 Issue 1, p33-41. 9p.

Subject Terms: *CHELATION therapy, *IRON overload, *IRON chelates, *IRON, *CHELATION

A Metal Chelation Therapy to Effectively Eliminate Breast Cancer and Intratumor Bacteria While Suppressing Tumor Metastasis by Copper Depletion and Zinc Ions Surge.

Authors: Xie, Yulin¹ (AUTHOR), Wang, Junrong¹ (AUTHOR), Li, Lei¹ (AUTHOR), Wang, Man¹ (AUTHOR), Sun, Jikai¹ (AUTHOR), Chang, Jiaying¹ (AUTHOR), Lin, Jun² (AUTHOR) jlin@ciac.ac.cn, Li, Chunxia¹ (AUTHOR) cxli@sdu.edu.cn

Source: Angewandte Chemie International Edition. 1/27/2025, Vol. 64 Issue 5, p1-17. 17p.

Subject Terms: *CHELATION therapy, *COPPER, *METASTASIS, *ZINC ions, *BREAST cancer, *CHELATING agents

Characteristics and outcome of 73 dogs with iron EDTA molluscicide ingestion in Melbourne, Australia (2013–2019).

Authors: Lauinger, CA¹ (AUTHOR) clarathevet@gmail.com, Wright, L² (AUTHOR), Smart, L^3,4,5 (AUTHOR)

Source: Australian Veterinary Journal. Jan/Feb2025, Vol. 103 Issue 1/2, p13-21. 9p.

Subject Terms: *DOGS, *CHELATION therapy, *IRON in the body, *SYMPTOMS, *INTESTINAL abnormalities, *POISONS, *TREATMENT effectiveness, *IRON chelates

Geographic Terms: MELBOURNE (Vic.)

Economic burden of adult patients with β-thalassaemia major in mainland China.

Authors: Zhen, Xuemei^1,2 (AUTHOR), Ming, Jing^1,2 (AUTHOR), Zhang, Runqi^1,2 (AUTHOR), Zhang, Shuo^1,2 (AUTHOR), Xie, Jing^1,2 (AUTHOR), Liu, Baoguo^1,2 (AUTHOR), Wang, Zijing³ (AUTHOR), Sun, Xiaojie^1,2 (AUTHOR) xiaojiesun@sdu.edu.cn, Shi, Lizheng⁴ (AUTHOR)

Source: Orphanet Journal of Rare Diseases. 8/29/2023, Vol. 18 Issue 1, p1-8. 8p.

Subject Terms: *MEDICAL care costs, *CHELATION therapy, *DIRECT costing, *ADULTS, *CHILD patients, SNOWBALL sampling

Geographic Terms: CHINA

Challenges and Opportunities of Metal Chelation Therapy in Trace Metals Overload-Induced Alzheimer's Disease.

Authors: Chaudhari, Vinay¹ (AUTHOR), Bagwe-Parab, Siddhi¹ (AUTHOR), Buttar, Harpal S.² (AUTHOR), Gupta, Shubhangi¹ (AUTHOR), Vora, Amisha¹ (AUTHOR), Kaur, Ginpreet¹ (AUTHOR) Ginpreet.Kaur@nmims.edu

Source: Neurotoxicity Research. Jun2023, Vol. 41 Issue 3, p270-287. 18p.

Subject Terms: *TRACE metals, *CHELATION therapy, *ALZHEIMER'S disease, *COPPER, *METALS, *TRACE elements

Iron chelation therapy.

Authors: Bruzzese, Antonella¹ (AUTHOR) antonella.bruzzese@gmail.com, Martino, Enrica Antonia¹ (AUTHOR), Mendicino, Francesco¹ (AUTHOR), Lucia, Eugenio¹ (AUTHOR), Olivito, Virginia¹ (AUTHOR), Bova, Carlo² (AUTHOR), Filippelli, Gianfranco³ (AUTHOR), Capodanno, Isabella⁴ (AUTHOR), Neri, Antonino⁵ (AUTHOR), Morabito, Fortunato⁶ (AUTHOR), Gentile, Massimo^1,7 (AUTHOR) massim.gentile@tiscali.it, Vigna, Ernesto¹ (AUTHOR)

Source: European Journal of Haematology. May2023, Vol. 110 Issue 5, p490-497. 8p.

Subject Terms: *CHELATION therapy, *IRON overload, *SICKLE cell anemia, *IRON in the body, *IRON

Regional Citrate Anticoagulation: Basic Principles and Clinical Applications.

Authors: BOYACI DUNDAR, Nazlihan¹ nazlihan_boyaci@yahoo.com

Source: Journal of Critical & Intensive Care. Apr2023, Vol. 14 Issue 1, p28-32. 5p.

Subject Terms: *ARTIFICIAL blood circulation, *CHELATION therapy, *CITRATES, *ANTICOAGULANTS, *HYPERNATREMIA, *METABOLIC disorders, *HYPOCALCEMIA, *HEMODIALYSIS

Beta Thalassemia in Children: Established Approaches, Old Issues, New Non-Curative Therapies, and Perspectives on Healing.

Authors: Origa, Raffaella¹ (AUTHOR) raffaella.origa@unica.it, Issa, Layal² (AUTHOR) layal.issa@karma-leb.org

Source: Journal of Clinical Medicine. Nov2024, Vol. 13 Issue 22, p6966. 23p.

Subject Terms: *BETA-Thalassemia, *CHELATION therapy, *CHILD patients, *GENE therapy, *GENOME editing

A Metal Chelation Therapy to Effectively Eliminate Breast Cancer and Intratumor Bacteria While Suppressing Tumor Metastasis by Copper Depletion and Zinc Ions Surge.

Authors: Xie, Yulin¹ (AUTHOR), Wang, Junrong¹ (AUTHOR), Li, Lei¹ (AUTHOR), Wang, Man¹ (AUTHOR), Sun, Jikai¹ (AUTHOR), Chang, Jiaying¹ (AUTHOR), Lin, Jun² (AUTHOR) jlin@ciac.ac.cn, Li, Chunxia¹ (AUTHOR) cxli@sdu.edu.cn

Source: Angewandte Chemie International Edition. Oct2024, p1. 18p. 10 Illustrations.

Subject Terms: *CHELATION therapy, *COPPER, *METASTASIS, *ZINC ions, *BREAST cancer, *CHELATING agents

Comparative Efficacy of Iron Chelation Therapies on Cardiac and Liver Iron Levels in Thalassemia Patients: A Systematic Review and Network Meta-Analysis.

Authors: Aleid, Abdulsalam¹ (AUTHOR), Almu, Dhiyaa² (AUTHOR), Almuwalad, Nada³ (AUTHOR), Alruwaili, Muhannad⁴ (AUTHOR), Alaryani, Khalid⁵ (AUTHOR), Alhaboob, Zeyad² (AUTHOR), Alwabari, Mohammed² (AUTHOR), Albenayyan, Saja² (AUTHOR), AlHarbi, Wahaj⁶ (AUTHOR), Shamsan, Abbas⁷ (AUTHOR), Al Mutair, Abbas⁸ (AUTHOR) abbas4080@hotmail.com

Source: Dr. Sulaiman Al Habib Medical Journal. Oct2024, Vol. 6 Issue 4, p157-168. 12p.

Subject Terms: *CARDIAC magnetic resonance imaging, *CHELATION therapy, *IRON overload, *HEMOLYTIC anemia, *GENETIC disorders

An "Iron-phagy" nanoparticle inducing irreversible mitochondrial damages for antitumor therapy.

Authors: Wang, Zixu^1,2 (AUTHOR), Xiang, Shanshan^1,2 (AUTHOR), Qiu, Yihe^1,2 (AUTHOR), Yu, Fangying³ (AUTHOR), Li, Sufen^1,2 (AUTHOR), Zhang, Shufen^1,2 (AUTHOR), Song, Guangtao^1,2 (AUTHOR), Xu, Yichong^1,2 (AUTHOR), Meng, Tingting^1,2 (AUTHOR), Yuan, Hong^1,2 (AUTHOR), Hu, Fuqiang^1,2 (AUTHOR) hufq@zju.edu.cn

Source: Journal of Controlled Release. Oct2024, Vol. 374, p400-414. 15p.

Subject Terms: *IRON chelates, *CHELATION therapy, *REACTIVE oxygen species, *NANOPARTICLES, *LYSOSOMES

Edetate Disodium–Based Chelation for Patients With a Previous Myocardial Infarction and Diabetes: TACT2 Randomized Clinical Trial.

Authors: Lamas, Gervasio A.¹, gervasio.lamas@msmc.com, Anstrom, Kevin J.², Navas-Acien, Ana³, Boineau, Robin⁴, Nemeth, Hayley⁵, Huang, Zhen⁵, Wen, Jun⁵, Rosenberg, Yves⁶, Stylianou, Mario⁶, Jones, Teresa L. Z.⁷, Joubert, Bonnie R.⁸, Yu, Qilu⁴, Santella, Regina M.³, Mon, Ana C.¹, Ujueta, Francisco¹, Escolar, Esteban¹, Nathan, David M.⁹, Fonseca, Vivian A.¹⁰, Aude, Y. Wady¹¹, Ehrman, Jonathan K.¹²

Source: JAMA: Journal of the American Medical Association; 9/10/2024, Vol. 332 Issue 10, p794-803, 10p

Clinical and laboratory profile and outcome in children with Wilson disease: an observational study in South India.

Authors: Srinivasan, Ranjini¹ (AUTHOR), Dominic, Shilpa¹ (AUTHOR), George, Antony¹ (AUTHOR) antonykuzhur@gmail.com

Source: Paediatrics & International Child Health. Sep-Nov2024, Vol. 44 Issue 3/4, p131-140. 10p.

Subject Terms: *HEPATOLENTICULAR degeneration, *CHELATION therapy, *COPPER, *CERULOPLASMIN, *JUVENILE diseases