Deubiquitination of DNM1L by USP3 triggers the development and metastasis of gallbladder carcinoma.

Authors: Liang, Ruopeng¹ (AUTHOR), Zhang, Xiaoxue² (AUTHOR), Wu, Shitao¹ (AUTHOR), Liu, Jing³ (AUTHOR), Zhai, Yunpeng¹ (AUTHOR), Lin, Chaojie¹ (AUTHOR), Wang, Zhenya¹ (AUTHOR), Zhang, Yi¹ (AUTHOR), Chen, Hao⁴ (AUTHOR) 11518223@zju.edu.cn, Zhu, Rongtao¹ (AUTHOR) fcczhurt@zzu.edu.cn

Source: Biology Direct. 4/7/2025, Vol. 20 Issue 1, p1-18. 18p.

Subject Terms: *MEDICAL sciences, *CELL transformation, *CYTOLOGY, *LIFE sciences, *MITOCHONDRIAL dynamics

Costunolide inhibits the progression of TPA-induced cell transformation and DMBA/TPA-induced skin carcinogenesis by regulation of AKT-mediated signaling.

Authors: Wi, Kwanhwan¹ (AUTHOR), Hwang, Sun-Young¹ (AUTHOR), Kim, Young-Gwon¹ (AUTHOR), Lee, Soong-In¹ (AUTHOR), Lee, Cheol-Jung² (AUTHOR), Bang, Geul³ (AUTHOR), Lee, Je-Ho⁴ (AUTHOR), Lee, Mee-Hyun¹ (AUTHOR) mhyun_lee@hanmail.net

Source: Cancer Cell International. 3/20/2025, Vol. 25 Issue 1, p1-16. 16p.

Subject Terms: *CELL transformation, *MEDICAL sciences, *CYTOLOGY, *LIFE sciences, *IMMUNOSTAINING

Inflammatory Transformation of Skin Basal Cells as a Key Driver of Cutaneous Aging.

Authors: Liu, Shupeng¹ (AUTHOR), Lu, Sheng¹ (AUTHOR), Pang, Zhiping¹ (AUTHOR), Li, Jiacheng¹ (AUTHOR), Zhou, Meijuan¹ (AUTHOR), Ding, Zhenhua (AUTHOR) dingzh@smu.edu.cn, Feng, Zhijun (AUTHOR) fengzhj18@lzu.edu.cn

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2617. 23p.

Subject Terms: *CELL transformation, *SKIN aging, *GENOME-wide association studies, *TRANSCRIPTOMES, *ANTIGEN processing, *NOTCH genes, KERATINOCYTE differentiation

Cellular Phenotypic Transformation During Atherosclerosis: The Potential Role of miRNAs as Biomarkers.

Authors: Wassaifi, Souhir¹ (AUTHOR), Kaeffer, Bertrand² (AUTHOR), Zarrouk, Sinda^1,3 (AUTHOR) sinda.zarrouk@pasteur.utm.tn

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 5, p2083. 19p.

Subject Terms: *CELL transformation, *PHENOTYPIC plasticity, *ATHEROSCLEROTIC plaque, *VASCULAR smooth muscle, *MUSCLE cells

DIA/SWATH-Mass Spectrometry Revealing Melanoma Cell Proteome Transformations with Silver Nanoparticles: An Innovative Comparative Study.

Authors: Martano, Simona¹ (AUTHOR), Faktor, Jakub² (AUTHOR), Kote, Sachin^2,3 (AUTHOR) ross.rinaldi@unisalento.it, Cascione, Mariafrancesca^1,3,4 (AUTHOR), Di Corato, Riccardo^3,4,5 (AUTHOR), Faktorova, Dagmar^5,6 (AUTHOR), Semeraro, Paola^6,7 (AUTHOR), Rizzello, Loris^7,8 (AUTHOR), Leporatti, Stefano^8,9 (AUTHOR), Rinaldi, Rosaria^1,3 (AUTHOR), De Matteis, Valeria^2,3,9 (AUTHOR) valeria.dematteis@unisalento.it

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 5, p2029. 24p.

Subject Terms: *CELL transformation, *SILVER nanoparticles, *COPPER, *PLANT extracts, *CARBOHYDRATE metabolism

E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence.

Authors: Avenhaus, Alicia^1,2 (AUTHOR), Velimirović, Milica^1,2 (AUTHOR), Bulkescher, Julia¹ (AUTHOR), Scheffner, Martin³ (AUTHOR), Hoppe-Seyler, Felix¹ (AUTHOR) hoppe-seyler@dkfz.de, Hoppe-Seyler, Karin¹ (AUTHOR)

Source: PLoS Pathogens. 2/7/2025, Vol. 21 Issue 2, p1-26. 26p.

Subject Terms: *CANCER cell growth, *CELL transformation, *HUMAN papillomavirus, *HEAD & neck cancer, *CANCER cell proliferation, *CELLULAR aging, *TUMOR suppressor proteins

The Role of Osteoprotegerin in Breast Cancer: Genetic Variations, Tumorigenic Pathways, and Therapeutic Potential.

Authors: Radhi, Janan Husain¹ (AUTHOR) 21200402@rcsi-mub.com, El-Hagrasy, Ahmed Mohsen Abbas¹ (AUTHOR) 20205713@rcsi-mub.com, Almosawi, Sayed Husain¹ (AUTHOR) 20204234@rcsi-mub.com, Alhashel, Abdullatif¹ (AUTHOR), Butler, Alexandra E.² (AUTHOR) abutler@rcsi-mub.com

Source: Cancers. Feb2025, Vol. 17 Issue 3, p337. 21p.

Subject Terms: *WORLD Wide Web, *NEOPLASTIC cell transformation, *BREAST tumors, *DESCRIPTIVE statistics, *GENE expression, *SYSTEMATIC reviews, *MEDLINE, *GENES, *ONLINE information services, *CELL receptors, *GENETICS, *SINGLE nucleotide polymorphisms, *MEMBRANE proteins, *BLOOD

Evaluation of the genotoxic and transformation potential induced by asbestos compared to cleavage fragments.

Authors: La Maestra, Sebastiano¹ (AUTHOR) Sebastiano.lamaestra@unige.it, Militello, Gaia M.² (AUTHOR), Alberti, Stefano³ (AUTHOR), Benvenuti, Mirko¹ (AUTHOR), Gaggero, Laura² (AUTHOR)

Source: Scientific Reports. 1/28/2025, Vol. 15 Issue 1, p1-13. 13p.

Subject Terms: *CELL transformation, *CHRYSOTILE, *ASBESTOS, *AMPHIBOLES, *OXIDATIVE stress, *LUNGS

Development a glycosylated extracellular vesicle-derived miRNA Signature for early detection of esophageal squamous cell carcinoma.

Authors: Chen, Jianlin^1,2 (AUTHOR), Zheng, Yue^1,2 (AUTHOR), Wang, Zhen³ (AUTHOR), Gao, Qi⁴ (AUTHOR), Hao, Kun⁵ (AUTHOR), Chen, Xiongfeng^1,6 (AUTHOR), Ke, Nantian^1,2 (AUTHOR), Lv, Xiang^1,2 (AUTHOR), Weng, Jiamiao^1,2 (AUTHOR), Zhong, Yuhong⁷ (AUTHOR), Huang, Zhixin^2,8 (AUTHOR), Fu, Miao⁹ (AUTHOR), Zhao, Lilan^1,10 (AUTHOR), Lin, Fan^1,11,12 (AUTHOR), Mi, Hui¹³ (AUTHOR), Tang, Haijun^1,14 (AUTHOR) tanghaijun16@163.com, Yu, Chundong^1,14,15 (AUTHOR) cdyu@xmu.edu.cn, Huang, Yi^1,2,14,16,17 (AUTHOR) hyi8070@126.com

Source: BMC Medicine. 1/23/2025, Vol. 23 Issue 1, p1-15. 15p.

Subject Terms: *SQUAMOUS cell carcinoma, *CELL transformation, *WHEAT germ, *CARCINOEMBRYONIC antigen, *EXTRACELLULAR vesicles

Neutrophil extracellular traps (NETs) are increased in rheumatoid arthritis-associated interstitial lung disease.

Authors: Xue, Jing¹ (AUTHOR), Nian, Miaomiao² (AUTHOR), Liang, Yangyang² (AUTHOR), Zhu, Zeqin² (AUTHOR), Hu, Zhenyu² (AUTHOR), Jia, Yuanyuan¹ (AUTHOR), Chi, Shuhong³ (AUTHOR) chi794613@163.com, Chen, Juan^1,4 (AUTHOR) chenjuan7419@163.com

Source: Respiratory Research. 1/22/2025, Vol. 26 Issue 1, p1-19. 19p.

Subject Terms: *CELL transformation, *INTERSTITIAL lung diseases, *PULMONARY fibrosis, *ENZYME-linked immunosorbent assay, *RHEUMATOID factor

Unveiling cell-type-specific microRNA networks through alternative polyadenylation in glioblastoma.

Authors: Cihan, Mert¹ (AUTHOR), Schmauck, Greta¹ (AUTHOR), Sprang, Maximilian¹ (AUTHOR), Andrade-Navarro, Miguel A.¹ (AUTHOR) andrade@uni-mainz.de

Source: BMC Biology. 1/21/2025, Vol. 23 Issue 1, p1-16. 16p.

Subject Terms: *CELL transformation, *MICRORNA genetics, *CYTOLOGY, *GLIOBLASTOMA multiforme, *LIFE sciences

The HOX Gene Family's Role as Prognostic and Diagnostic Biomarkers in Hematological and Solid Tumors.

Authors: Kopec, Kaci¹ (AUTHOR) kkopec@student.touro.edu, Quaranto, Danielle¹ (AUTHOR) dquarant@student.touro.edu, DeSouza, Nicole R.¹ (AUTHOR) ndesouza@student.touro.edu, Jarboe, Tara¹ (AUTHOR) tseymour@student.touro.edu, Islam, Humayun K.^1,2 (AUTHOR) humayun.islam@wmchealth.org, Moscatello, Augustine^1,2 (AUTHOR) a_moscatello@nymc.edu, Li, Xiu-Min^1,2,3 (AUTHOR) xiumin_li@nymc.edu, Geliebter, Jan^1,2 (AUTHOR) jan_geliebter@nymc.edu, Tiwari, Raj K.^1,2 (AUTHOR)

Source: Cancers. Jan2025, Vol. 17 Issue 2, p262. 31p.

Subject Terms: *HEMATOLOGIC malignancies, *NEOPLASTIC cell transformation, *EMBRYOLOGY, *TUMOR markers, *TRANSCRIPTION factors, *GENES, *METASTASIS, *TUMORS

The endonuclease activity of MCPIP1 controls the neoplastic transformation of epithelial cells via the c-Met/CD44 axis.

Authors: Marona, Paulina¹ (AUTHOR), Myrczek, Rafał^1,2 (AUTHOR), Piasecka, Iga¹ (AUTHOR), Gorka, Judyta¹ (AUTHOR), Kwapisz, Oliwia^1,2 (AUTHOR), Pospiech, Ewelina^3,4 (AUTHOR), Rys, Janusz⁵ (AUTHOR), Jura, Jolanta¹ (AUTHOR), Miekus, Katarzyna¹ (AUTHOR) katarzyna.miekus@uj.edu.pl

Source: Cell Communication & Signaling. 1/15/2025, Vol. 23 Issue 1, p1-18. 18p.

Subject Terms: *NEOPLASTIC cell transformation, *CYTOLOGY, *MEDICAL sciences, *LIFE sciences, *CANCER stem cells

Differential Activity and Expression of Proteasome in Seminiferous Epithelium During Mouse Spermatogenesis.

Authors: Zapata-Carmona, Héctor¹ (AUTHOR) hector.zapata@uantof.cl, Díaz, Emilce Silvina¹ (AUTHOR) emilce.diaz@uantof.cl, Morales, Patricio^1,2 (AUTHOR) patricio.morales@uantof.cl, Jara, Marco¹ (AUTHOR) marco.jara@uantof.cl

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p494. 18p.

Subject Terms: *CELL transformation, *SEMINIFEROUS tubules, *PROTEOLYSIS, *PROTEIN kinases, *SPERMATOGENESIS

TREM2 affects DAM-like cell transformation in the acute phase of TBI in mice by regulating microglial glycolysis.

Authors: Wang, Lin^1,2 (AUTHOR), Ouyang, Diqing¹ (AUTHOR), Li, Lin¹ (AUTHOR), Cao, Yunchuan¹ (AUTHOR), Wang, Yingwen¹ (AUTHOR), Gu, Nina¹ (AUTHOR), Zhang, Zhaosi¹ (AUTHOR), Li, Zhao³ (AUTHOR), Tang, Shuang⁴ (AUTHOR), Tang, Hui² (AUTHOR), Zhang, Yuan² (AUTHOR) 1013791298@qq.com, Sun, Xiaochuan¹ (AUTHOR) sunxiaochuan@cqmu.edu.cn, Yan, Jin¹ (AUTHOR) yanjin@hospital.cqmu.edu.cn

Source: Journal of Neuroinflammation. 1/13/2025, Vol. 22 Issue 1, p1-26. 26p.

Subject Terms: *CELL transformation, *MYELOID cells, *WESTERN immunoblotting, *BRAIN injuries, *KNOCKOUT mice

Vacuolating Cytotoxin A (VacA) and Extracellular Vesicles in Helicobacter pylori: Two Key Arms in Disease Development.

Authors: Alavi Rostami, Seyedeh Faride¹ Iranrastmanesh@tbzmed.ac.ir, Khaledi, Mansoor^2,3, Dalilian, Fatemeh⁴, Mehboodi, Mahtab⁵, Akbari, Atefeh⁶, Shams Abadi, Milad Shahini², Ataloo, Pouria Khodaei⁷, Mohsenipour, Zeinab⁸ mohsenipourz20@gmail.com, Rastmanesh, Samad⁹

Source: Iranian Journal of Pathology. Winter2025, Vol. 20 Issue 1, p1-17. 17p.

Subject Terms: *CELL transformation, *EXTRACELLULAR vesicles, *DISEASE risk factors, *HELICOBACTER pylori infections, *HELICOBACTER diseases, *GASTRIC mucosa

Epidermal growth factor receptor ligands enriched in follicular fluid exosomes promote oncogenesis of fallopian tube epithelial cells.

Authors: Khine, Aye Aye¹ (AUTHOR), Chen, Pao-Chu² (AUTHOR), Chen, Ying-Hsi² (AUTHOR), Chu, Sung-Chao^3,4 (AUTHOR), Huang, Hsuan-Shun¹ (AUTHOR) huang.sansam@gmail.com, Chu, Tang-Yuan^1,2,4,5 (AUTHOR) hidrchu@gmail.com

Source: Cancer Cell International. 12/21/2024, Vol. 24 Issue 1, p1-14. 14p.

Subject Terms: *EPIDERMAL growth factor receptors, *CELL transformation, *EPIDERMAL growth factor, *PROTEIN-tyrosine kinases, *LIFE sciences

The Functional Interaction Between Epstein–Barr Virus and MYC in the Pathogenesis of Burkitt Lymphoma.

Authors: Solares, Sandra¹ (AUTHOR) sandra.solares@alumnos.unican.es, León, Javier¹ (AUTHOR), García-Gutiérrez, Lucía¹ (AUTHOR) lucia.garcia@unican.es

Source: Cancers. Dec2024, Vol. 16 Issue 24, p4212. 30p.

Subject Terms: *PHENOMENOLOGICAL biology, *NEOPLASTIC cell transformation, *IMMUNOGLOBULINS, *CELL proliferation, *EPSTEIN-Barr virus, *ONCOGENES, *MICROBIOLOGY, *NASOPHARYNX cancer, *B cell lymphoma

Th9 and Th17 Cells in Human Ulcerative Colitis-Associated Dysplastic Lesions.

Authors: Cui, Guanglin^1,2 (AUTHOR) guanglin.cui@nord.no, Yuan, Aping¹ (AUTHOR), Sørbye, Sveinung W³ (AUTHOR), Florholmen, Jon⁴ (AUTHOR)

Source: Clinical Medicine Insights: Oncology. 12/7/2024, p1-9. 9p.

Subject Terms: *RISK assessment, *NEOPLASTIC cell transformation, *T cells, *RESEARCH funding, *PRECANCEROUS conditions, *CELL physiology, *ULCERATIVE colitis, *COLORECTAL cancer, *IMMUNOHISTOCHEMISTRY, *EPITHELIUM, *ADENOMA, *COMPARATIVE studies, *INTERLEUKINS, *DISEASE risk factors, *DISEASE complications

Impairment of Intermediate Filament Expression Reveals Impact on Cell Functions Independent from Keratinocyte Transformation.

Authors: Klein, Charlotte^1,2 (AUTHOR) charlotte.klein@uniklinik-freiburg.de, Ramminger, Imke^1,3 (AUTHOR) imke.ramminger@uniklinik-freiburg.de, Bai, Shuoqiu¹ (AUTHOR) shuoqiu.bai@uniklinik-freiburg.de, Steinberg, Thorsten¹ (AUTHOR) pascal.tomakidi@uniklinik-freiburg.de, Tomakidi, Pascal¹ (AUTHOR)

Source: Cells (2073-4409). Dec2024, Vol. 13 Issue 23, p1960. 29p.

Subject Terms: *CELL transformation, *CELL physiology, *TISSUE physiology, *CYTOPLASMIC filaments, *VIMENTIN, *HOMEOSTASIS, KERATINOCYTE differentiation