Revealing novel CD8+ T-cell epitopes from the H5N1 avian influenza virus in HBW/B1 haplotype ducks

Authors: Wanlin Jiao, Yingyi Chen, Zimin Xie, Li Zhao, Shanyao Du, Mulin Ma, Ming Liao, Manman Dai

Source: Veterinary Research, Vol 55, Iss 1, Pp 1-9 (2024)

Subject Terms: H5N1 AIV, MHC B1 haplotype ducks, CD8+ T-cell response, MHC B1-restricted T-cell epitopes, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/1297-9716

Access URL: https://doaj.org/article/49502e9235b9419b9dc5566ed90bb6fd

The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitments

Authors: Abdullah, Leena ¹, Emiliani, Francesco E. ^{2, 7}, Vaidya, Chinmay M. ^{1, 3, 7}, Stuart, Hannah ^{2, 7}, Musial, Shawn C. ¹, Kolling, Fred W. ⁵, Obar, Joshua J. ¹, Rosato, Pamela C. ^{1, 5}, Ackerman, Margaret E. ^{3, 5}, Song, Li ^{4, 5}, McKenna, Aaron ^{2, 5}, Huang, Yina H. ^{1, 5, 6, 8, ∗}

Source: In Immunity 11 March 2025 58(3):601-615

A fusion protein that targets antigen-loaded extracellular vesicles to B cells enhances antigen-specific T cell expansion

Authors: Offens, Annemarijn ^{a, b, c}, Teeuwen, Loes ^{a, b, c}, Gucluler Akpinar, Gozde ^{a, b, c}, Steiner, Loïc ^{a, b, c}, Kooijmans, Sander ^{d, e, f}, Mamand, Doste ^{g, h, i, j}, Weissinger, Hannah ^{a, b}, Käll, Alexander ^{a, b}, Eldh, Maria ^{a, b, c}, Wiklander, Oscar P.B. ^{g, i, j}, El-Andaloussi, Samir ^{g, h, i}, Karlsson, Mikael C.I. ^k, Vader, Pieter ^d, Gabrielsson, Susanne ^{a, b, c, ⁎}

Source: In Journal of Controlled Release 10 June 2025 382

Immunoreactivity Analysis of MHC-I Epitopes Derived from the Nucleocapsid Protein of SARS-CoV-2 via Computation and Vaccination

Authors: Dongbo Jiang, Zilu Ma, Junqi Zhang, Yubo Sun, Tianyuan Bai, Ruibo Liu, Yongkai Wang, Liang Guan, Shuaishuai Fu, Yuanjie Sun, Yuanzhe Li, Bingquan Zhou, Yulin Yang, Shuya Yang, Yuanhang Chang, Baozeng Sun, Kun Yang

Source: Vaccines, Vol 12, Iss 11, p 1214 (2024)

Subject Terms: SARS-CoV-2, nucleocapsid protein (NP), MHC-I-restricted epitopes, CD8+ T cell response, immunogenicity, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/11/1214; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/5bcaeebbf04d46f783091cc538c78448

HBsAg level defines different clinical phenotypes of HBeAg(−) chronic HBV infection related to HBV polymerase-specific CD8+ cell response quality

Authors: Julia Peña-Asensio, Henar Calvo-Sánchez, Joaquín Miquel-Plaza, Eduardo Sanz-de-Villalobos, Alejandro González-Praetorius, Alberto Delgado-Fernandez, Miguel Torralba, Juan-Ramón Larrubia

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: HBV inactive carrier, functional HBV-specific CD8 + T-cell response, HBV immune control, liver fibrosis progression, HBsAg, HBV eAg(-) infection gray-zone, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1352929/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/15262ea5052547689d84e817db95f44b

Reconstituted dry powder formulations of ZnO-adjuvanted ovalbumin induce equivalent antigen specific antibodies but lower T cell responses than ovalbumin adjuvanted with Alhydrogel® or cationic adjuvant formulation 01 (CAF®01)

Authors: Hellfritzsch, Marie ^{a, 1}, Christensen, Dennis ^{b, 2}, Foged, Camilla ^c, Scherließ, Regina ^{a, ⁎}, Thakur, Aneesh ^{c, 3, ⁎}

Source: In International Journal of Pharmaceutics 15 December 2023 648

Comparative analysis of the impact of 40 adenovirus types on dendritic cell activation and CD8+ T cell proliferation capacity for the identification of favorable immunization vector candidates

Authors: Xiaoyan Wang, Mario Hetzel, Wenli Zhang, Anja Ehrhardt, Wibke Bayer

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: human adenovirus (HAdV), adenoviral vector, adenovirus-based immunization, CD8 T cell response, CD8+ T cell response, T cell response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286622/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/39f580e6dd194b41ab630e5018fa1724

Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts

Authors: M. Eyad Khorki, Tiffany Shi, Eileen E. Cianciolo, Ashley R. Burg, P. Chukwunalu Chukwuma, Jennifer L. Picarsic, Mary K. Morrice, E. Steve Woodle, Jonathan S. Maltzman, Autumn Ferguson, Jonathan D. Katz, Brian M. Baker, David A. Hildeman

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: transplant, cross-reactivity, TCR (T cell receptor), LCMV (lymphocytic choriomeningitis virus), transplantation, CD8+ T cell response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1287546/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/555d23a18c6843c39ebce9e0a10efea5

Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response

Authors: Julia K. Büttner, Sara Becker, Annette Fink, Melanie M. Brinkmann, Rafaela Holtappels, Matthias J. Reddehase, Niels A. Lemmermann

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: CD8 T cell response, m152/gp40, antigen presentation, antigen cross-presentation, antigen presenting cell (APC), murine cytomegalovirus (mCMV), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1272166/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/79934bb9fe914af98a35679105d46474

Leveraging T-cell receptor – epitope recognition models to disentangle unique and cross-reactive T-cell response to SARS-CoV-2 during COVID-19 progression/resolution

Authors: Anna Postovskaya, Alexandra Vujkovic, Tessa de Block, Lida van Petersen, Maartje van Frankenhuijsen, Isabel Brosius, Emmanuel Bottieau, Christophe Van Dijck, Caroline Theunissen, Sabrina H. van Ierssel, Erika Vlieghe, Esther Bartholomeus, Kerry Mullan, Wim Adriaensen, Guido Vanham, Benson Ogunjimi, Kris Laukens, Koen Vercauteren, Pieter Meysman

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: TCR repertoire analysis, CD8+ T-cell response, COVID-19, SARS-CoV-2 epitopes, immunoinformatics, cross-reactive T-cell response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1130876/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ba2fc2c6e4b2476896a2379ad77d5b6f

The resurgence of the Adora2b receptor as an immunotherapeutic target in pancreatic cancer

Authors: Lincoln N. Strickland, Erika Y. Faraoni, Wei Ruan, Xiaoyi Yuan, Holger K. Eltzschig, Jennifer M. Bailey-Lundberg

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: immunotherapy, pancreatic adenocarcinoma, hypoxia, Adenosine receptor 2B, CD8+ T cell response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163585/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5d955631d71d4c68a8d29668f1d1749d

Ad5-nCoV Vaccination Could Induce HLA-E Restricted CD8+ T Cell Responses Specific for Epitopes on Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein

Authors: Yuling Wang, Lu Yang, Kang Tang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Boquan Jin, Yuan Zhang, Ran Zhuang, Ying Ma

Source: Viruses, Vol 16, Iss 1, p 52 (2023)

Subject Terms: severe acute respiratory syndrome coronavirus 2, Ad5-nCoV, vaccination, HLA-E, CD8+ T cell response, epitope, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/1/52; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/af5b13d3f88542ebbd8a408dd0467186

Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles

Authors: Andreas Walker, Tatjana Schwarz, Janine Brinkmann-Paulukat, Karin Wisskirchen, Christopher Menne, Elahe Salimi Alizei, Helenie Kefalakes, Martin Theissen, Daniel Hoffmann, Julian Schulze zur Wiesch, Mala K. Maini, Markus Cornberg, Anke RM Kraft, Verena Keitel, Hans H. Bock, Peter A. Horn, Robert Thimme, Heiner Wedemeyer, Falko M. Heinemann, Tom Luedde, Christoph Neumann-Haefelin, Ulrike Protzer, Jörg Timm

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: hepatitis B virus, CD8 T cell response, TCR-engineered T cells, immune escape, chronic infection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1045498/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a835df343e524209b827b09b26d8af46

In silico and in vitro arboviral MHC class I-restricted-epitope signatures reveal immunodominance and poor overlapping patterns

Authors: Ágata Lopes-Ribeiro, Franklin Pereira Araujo, Patrícia de Melo Oliveira, Lorena de Almeida Teixeira, Geovane Marques Ferreira, Alice Aparecida Lourenço, Laura Cardoso Corrêa Dias, Caio Wilker Teixeira, Henrique Morais Retes, Élisson Nogueira Lopes, Alice Freitas Versiani, Edel Figueiredo Barbosa-Stancioli, Flávio Guimarães da Fonseca, Olindo Assis Martins-Filho, Moriya Tsuji, Vanessa Peruhype-Magalhães, Jordana Grazziela Alves Coelho-dos-Reis

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: MHC-I peptides, CD8+T cell response, arbovirus, overlapping peptides, HLA-A2-restricted peptides, immunoinformatics, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1035515/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e838f5fafa6643c18b8786050d218b50

Immune responses to an inactivated Johne’s disease vaccine in cattle

Authors: R K CHAITANYA, Y KRISHNA MOHAN REDDY, A THANGAVELU

Source: Indian Journal of Animal Sciences, Vol 92, Iss 10 (2022)

Subject Terms: Antibodies, CD4 and CD8 T cell response, IFN-γ, Johne’s disease, Vaccine efficacy, Animal culture, SF1-1100

File Description: electronic resource

Relation: https://epubs.icar.org.in/index.php/IJAnS/article/view/113137; https://doaj.org/toc/0367-8318; https://doaj.org/toc/2394-3327

Access URL: https://doaj.org/article/c9e3267f33d040d7a66a197ac3d4509a

TLR7 Agonist GS–9620 Combined with Nicotinamide Generate Viral Reactivation in Seronegative SHIVSF162P3-Infected Rhesus Monkeys

Authors: Zhe Cong, Yuting Sun, Cui Dang, Chenbo Yang, Jingjing Zhang, Jiahan Lu, Ting Chen, Qiang Wei, Wei Wang, Jing Xue

Source: Biomedicines, Vol 11, Iss 6, p 1707 (2023)

Subject Terms: GS–9620, nicotinamide, latency-reversing agent, SHIVSF162P3, rhesus macaques, CD8+ T cell response, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/6/1707; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/89070b43da944da6bae2ef415483090f

Newly Designed Poxviral Promoters to Improve Immunogenicity and Efficacy of MVA-NP Candidate Vaccines against Lethal Influenza Virus Infection in Mice

Authors: Martin C. Langenmayer, Anna-Theresa Luelf-Averhoff, Lisa Marr, Sylvia Jany, Astrid Freudenstein, Silvia Adam-Neumair, Alina Tscherne, Robert Fux, Juan J. Rojas, Andreas Blutke, Gerd Sutter, Asisa Volz

Source: Pathogens, Vol 12, Iss 7, p 867 (2023)

Subject Terms: influenza A virus, nucleoprotein, Modified Vaccinia virus Ankara, vaccine, synthetic VACV promoter, CD8+ T cell response, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/12/7/867; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/ed108fa0846b4fb79076124651caa712

Humoral and Cellular Immunogenicity and Safety of Five Different SARS-CoV-2 Vaccines in Patients With Autoimmune Rheumatic and Musculoskeletal Diseases in Remission or With Low Disease Activity and in Healthy Controls: A Single Center Study

Authors: Gábor J. Szebeni, Nikolett Gémes, Dániel Honfi, Enikő Szabó, Patrícia Neuperger, József Á. Balog, Lajos I. Nagy, Zoltán Szekanecz, László G. Puskás, Gergely Toldi, Attila Balog

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: SARS-CoV-2 vaccination, rheumatic and musculoskeletal diseases, anti-RBD neutralizing antibodies, CD4+ T-cell response, CD8+ T-cell response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.846248/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/19da92fcde764539a810a447695aa21a

Diversity of HLA-A2-Restricted and Immunodominant Epitope Repertoire of Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Protein: Novel Insights among N-Terminal, Central and C-Terminal Regions

Authors: Thaiza Aline Pereira-Santos, Anderson Santos da Rocha, Ágata Lopes-Ribeiro, Laura Cardoso Corrêa-Dias, Patrícia Melo-Oliveira, Erik Vinicius de Sousa Reis, Flávio Guimarães da Fonseca, Edel Figueiredo Barbosa-Stancioli, Moriya Tsuji, Jordana Grazziela Alves Coelho-dos-Reis

Source: Biomolecules, Vol 13, Iss 3, p 545 (2023)

Subject Terms: HTLV-1, Tax, MHC-I peptides, CD8+ T-cell response, HLA-A2 haplotype, immunoinformatics, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/3/545; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/9b8c1527422d406c8a632180ef7c32a6

The immune response to influenza in older humans: beyond immune senescence

Authors: Janet E. McElhaney, Chris P. Verschoor, Melissa K. Andrew, Laura Haynes, George A. Kuchel, Graham Pawelec

Source: Immunity & Ageing, Vol 17, Iss 1, Pp 1-10 (2020)

Subject Terms: Influenza, Influenza vaccination, Hemagglutination inhibition antibody response, Broadly neutralizing antibodies, CD4 and CD8 T cell response, Cytokines, Immunologic diseases. Allergy, RC581-607, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12979-020-00181-1; https://doaj.org/toc/1742-4933

Access URL: https://doaj.org/article/db4a68d7df644345ac26d0107b5998a1