Comparative evaluation of different modalities for measuring in vivo carnosine levels.

Authors: Amraotkar, Alok R.^1,2 (AUTHOR), Hoetker, David^1,2 (AUTHOR), Negahdar, Mohammad J.³ (AUTHOR), Ng, Chin K.² (AUTHOR), Lorkiewicz, Pawel^1,4 (AUTHOR), Owolabi, Ugochukwu S.¹ (AUTHOR), Baba, Shahid P.^1,2 (AUTHOR), Bhatnagar, Aruni^1,2 (AUTHOR), O'Toole, Timothy E.^1,2 (AUTHOR) tim.otoole@louisville.edu

Source: PLoS ONE. 3/27/2024, Vol. 19 Issue 3, p1-15. 15p.

Subject Terms: *PROTON magnetic resonance spectroscopy, *CARNOSINE, *TANDEM mass spectrometry, *LEG muscles, *HOMEOSTASIS

The Anti-Cancer Activity of the Naturally Occurring Dipeptide Carnosine: Potential for Breast Cancer.

Authors: Maugeri, Salvatore¹ (AUTHOR), Sibbitts, Jay^2,3 (AUTHOR), Privitera, Anna^1,4 (AUTHOR), Cardaci, Vincenzo^5,6 (AUTHOR), Di Pietro, Lucia^1,5 (AUTHOR), Leggio, Loredana⁴ (AUTHOR), Iraci, Nunzio⁴ (AUTHOR), Lunte, Susan M.^2,3,7 (AUTHOR), Caruso, Giuseppe^1,8 (AUTHOR) giuseppe.caruso2@unict.it

Source: Cells (2073-4409). Nov2023, Vol. 12 Issue 22, p2592. 19p.

Subject Terms: *DIPEPTIDES, *CARNOSINE, *VASCULAR endothelial growth factors, *ANTINEOPLASTIC agents, *CYTOCHROME oxidase, *BREAST cancer

Possible Inhibition of Renal Protein Glycation by Carnosine and Tocopherol in Diabetic Rat.

Authors: Huwait, Etimad^1,2, Al-Ghamdi, Maryam A.^1,2, Al-Shehri, Faisal S.³, Moselhy, Said S.⁴ moselhy6@hotmail.com

Source: Pharmacognosy Research. Jul-Sep2023, Vol. 15 Issue 3, p562-565. 4p.

Subject Terms: *CARNOSINE, *INFLAMMATORY mediators, *DIETARY supplements, *GLYCOSYLATED hemoglobin, *PROTEINS, *VITAMIN E

Effect of muscle fibre types and carnosine levels on the expression of carnosine-related genes in pig skeletal muscle.

Authors: Kalbe, Claudia¹ (AUTHOR), Metzger, Katharina² (AUTHOR), Gariépy, Claude³ (AUTHOR), Palin, Marie-France⁴ (AUTHOR) Mariefrance.palin@agr.gc.ca

Source: Histochemistry & Cell Biology. Jul2023, Vol. 160 Issue 1, p63-77. 15p.

Subject Terms: *CARNOSINE, *GENE expression, *MYOBLASTS, *SKELETAL muscle, *GENETIC transcription regulation, *FIBERS

Lipidome Investigation of Carnosine Effect on Nude Mice Skin to Prevent UV-A Damage.

Authors: Zoanni, Beatrice¹ (AUTHOR) beatrice.zoanni@unimi.it, Aiello, Gilda^1,2 (AUTHOR) gilda.aiello@uniroma5.it, Negre-Salvayre, Anne³ (AUTHOR) anne.negre-salvayre@inserm.fr, Aldini, Giancarlo¹ (AUTHOR) giancarlo.aldini@unimi.it, Carini, Marina¹ (AUTHOR) alfonsina.damato@unimi.it, D'Amato, Alfonsina¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Jun2023, Vol. 24 Issue 12, p10009. 15p.

Subject Terms: *CARNOSINE, *SKIN proteins, *REACTIVE oxygen species, *MASS spectrometry, *LIPIDS

The Therapeutic Potential of Novel Carnosine Formulations: Perspectives for Drug Development.

Authors: Bonaccorso, Angela^1,2 (AUTHOR), Privitera, Anna^1,3 (AUTHOR), Grasso, Margherita⁴ (AUTHOR), Salamone, Sonya¹ (AUTHOR), Carbone, Claudia^1,2 (AUTHOR), Pignatello, Rosario^1,2 (AUTHOR), Musumeci, Teresa^1,2 (AUTHOR), Caraci, Filippo^1,4 (AUTHOR), Caruso, Giuseppe^1,4 (AUTHOR) giuseppe.caruso2@unict.it

Source: Pharmaceuticals (14248247). Jun2023, Vol. 16 Issue 6, p778. 26p.

Subject Terms: *DRUG development, *CARNOSINE, *BLOOD-brain barrier, *DRUG delivery systems, *ALZHEIMER'S disease, *ENERGY metabolism

Acute balenine supplementation in humans as a natural carnosinase-resistant alternative to carnosine.

Authors: de Jager, Sarah¹ (AUTHOR), Vermeulen, An² (AUTHOR), De Baere, Siegrid³ (AUTHOR), Van der Stede, Thibaux^1,4 (AUTHOR), Lievens, Eline¹ (AUTHOR), Croubels, Siska³ (AUTHOR), Jäger, Ralf⁵ (AUTHOR), Purpura, Martin⁵ (AUTHOR), Bourgois, Jan G.¹ (AUTHOR), Derave, Wim¹ (AUTHOR) wim.derave@ugent.be

Source: Scientific Reports. 4/20/2023, Vol. 13 Issue 1, p1-10. 10p.

Subject Terms: *CARNOSINE, *DIETARY supplements, *ERGOGENIC aids, *BIOAVAILABILITY

The short‐term feeding of low‐ and high‐histidine diets prior to market affects the muscle carnosine and anserine contents and meat quality of broilers.

Authors: Sharula¹ (AUTHOR), Kai, Shinichi² (AUTHOR), Okada, Toru³ (AUTHOR), Shimamoto, Saki¹ (AUTHOR), Fujimura, Shinobu¹ (AUTHOR) fujimura@agr.niigata-u.ac.jp

Source: Animal Science Journal. Jan2023, Vol. 94 Issue 1, p1-11. 11p.

Subject Terms: *MEAT quality, *CARNOSINE, *COLOR of meat, *ERECTOR spinae muscles, *SHEARING force, *DIET, *HISTIDINE

Cyclic homodimer formation by singlet oxygen-mediated oxidation of carnosine.

Authors: Kawakami, Hiroko^1,2, Itakura, Yuki¹ t.yoshiya@peptide.co.jp, Yamamoto, Tetsuya¹, Yoshiya, Taku^1,3

Source: Frontiers in Chemistry. 2024, p1-6. 6p.

Subject Terms: *REACTIVE oxygen species, *CARNOSINE, *NUCLEOPHILES

PEGylation renders carnosine resistant to hydrolysis by serum carnosinase and increases renal carnosine levels.

Authors: Zhang, Shiqi¹ (AUTHOR) zhangshiqi@ahmu.edu.cn, Yang, Guang¹ (AUTHOR), Zhang, Qinqin¹ (AUTHOR), Fan, Yuying¹ (AUTHOR), Tang, Mingna¹ (AUTHOR), Shen, Liuhai² (AUTHOR), Zhu, Dongchun³ (AUTHOR), Zhang, Guiyang⁴ (AUTHOR), Yard, Benito⁵ (AUTHOR)

Source: Amino Acids. 7/4/2024, Vol. 56 Issue 1, p1-9. 9p.

Subject Terms: *CARNOSINE, *DIABETIC nephropathies, *HYDROLYSIS

New Derivative of Pyrrole and Carnosine: Synthesis, Physicochemical Properties, and Biological Acivity.

Authors: Fedorova, T. N.¹ (AUTHOR) tnf51@bk.ru, Kulikova, O. I.¹ (AUTHOR), Migulin, V. A.² (AUTHOR), Muzychuk, O. A.¹ (AUTHOR), Abaimov, D. A.¹ (AUTHOR), Stvolinsky, S. L.¹ (AUTHOR)

Source: Pharmaceutical Chemistry Journal. Jul2024, Vol. 58 Issue 4, p617-624. 8p.

Subject Terms: *OXIDATIVE stress, *CARNOSINE, *MASS spectrometry, *PYRROLES, *NEUROBLASTOMA

Carnosine Potentiates Doxorubicin-Induced Cytotoxicity in Resistant NCI/ADR-RES Cells by Inhibiting P-Glycoprotein—In Silico and In Vitro Evidence.

Authors: Morsy, Mohamed A.^1,2 (AUTHOR) momorsy@kfu.edu.sa, Kandeel, Mahmoud^3,4 (AUTHOR), Ibrahim, Ahmed R. N.^5,6 (AUTHOR), Abdel-Gaber, Seham A.² (AUTHOR), Jacob, Shery⁷ (AUTHOR), Venugopala, Katharigatta N.^1,8 (AUTHOR), Shinu, Pottathil⁹ (AUTHOR), El-Daly, Mahmoud¹⁰ (AUTHOR)

Source: Molecules. Nov2022, Vol. 27 Issue 21, p7383. 12p.

Subject Terms: *CARNOSINE, *DOXORUBICIN, *P-glycoprotein, *CANCER-related mortality, *DRUG resistance, *MOLECULAR docking

Protective effect of melatonin and carnosine against radiation induced kidney injury.

Authors: Turkyilmaz, Ismet Burcu¹ (AUTHOR) burcut@iuc.edu.tr, Us, Huseyin² (AUTHOR), Sezen Us, Ayca² (AUTHOR), Karabulut-Bulan, Omur² (AUTHOR), Yanardag, Refiye¹ (AUTHOR)

Source: Journal of Radioanalytical & Nuclear Chemistry. Sep2022, Vol. 331 Issue 9, p3551-3561. 11p. 1 Color Photograph, 6 Graphs.

Subject Terms: *CARNOSINE, *KIDNEY injuries, *MELATONIN, *RADIATION, *LABORATORY rats

Unveiling the Hidden Therapeutic Potential of Carnosine, a Molecule with a Multimodal Mechanism of Action: A Position Paper.

Authors: Caruso, Giuseppe^1,2 (AUTHOR) giuseppe.caruso2@unict.it

Source: Molecules. May2022, Vol. 27 Issue 10, p3303-3303. 14p.

Subject Terms: *CARNOSINE, *REACTIVE nitrogen species, *REACTIVE oxygen species, *MICROGLIA, *MOLECULES, *IN vivo studies

Antioxidant Effect of Carnosine and Carnosine Dinitrosyl Iron Complexes under the Conditions Modeling Peroxidation of Biomolecules.

Authors: Nasybullina, E. I.¹, Kosmachevskaya, O. V.¹, Shumaev, K. B.¹, Topunov, A. F.¹, aftopunov@yandex.ru

Source: Applied Biochemistry & Microbiology; Oct2024, Vol. 60 Issue 5, p812-820, 9p

The protective role of carnosine against type 2 diabetes‐induced cognitive impairment.

Authors: Wang, Qian¹ (AUTHOR), Tripodi, Nicholas¹ (AUTHOR), Valiukas, Zachary¹ (AUTHOR), Bell, Simon M.² (AUTHOR), Majid, Arshad² (AUTHOR), de Courten, Barbora^3,4 (AUTHOR), Apostolopoulos, Vasso^1,5 (AUTHOR), Feehan, Jack¹ (AUTHOR) jack.feehan@vu.edu.au

Source: Food Science & Nutrition. Jun2024, Vol. 12 Issue 6, p3819-3833. 15p.

Subject Terms: Cognition disorders, Tropanes, Type 2 diabetes, Carnosine, Alkaloids

Proteinase Resistance of Carnosine, Pyrrolylcarnosine and Salicylcarnosine.

Authors: Shevchenko, K. V.¹ (AUTHOR) ATCarma@mail.ru, Nagaev, I. Yu.¹ (AUTHOR), Kulikova, O. I.² (AUTHOR), Stvolinsky, S. L.² (AUTHOR), Shevchenko, V. P.¹ (AUTHOR), Myasoedov, N. F.¹ (AUTHOR)

Source: Russian Journal of Bioorganic Chemistry. Apr2024, Vol. 50 Issue 2, p401-407. 7p.

Subject Terms: *CARNOSINE, *CELL membranes, *CARBOXYPEPTIDASES, *BLOOD plasma, *SALICYLIC acid

A comprehensive review on physiological and biological activities of carnosine: turning from preclinical facts to potential clinical applications.

Authors: Kumar, Akshita, Suryakumar, Geetha, Singh, Som Nath, Rathor, Richa

Source: Naunyn-Schmiedeberg's Archives of Pharmacology; Feb2025, Vol. 398 Issue 2, p1341-1366, 26p

Subject Terms: PHYSICAL mobility, CARNOSINE, SKELETAL muscle, COGNITIVE ability, HISTIDINE

Inhibitory Potential of Carnosine and Aminoguanidine Towards Glycation and Fibrillation of Albumin: In-vitro and Simulation Studies.

Authors: Khan, Mohammad Rashid, Khan, Mohd Shahnawaz, Manoharan, Rupavarshini, Karthikeyan, Subramani, Alhosaini, Khaled, Odeibat, Humza Ahmad Mohammad, Ahmad, MD. Irshad, Al-Okail, Majed, Al-twaijry, Nojood

Source: Journal of Fluorescence; Jan2025, Vol. 35 Issue 1, p29-42, 14p

Subject Terms: ADVANCED glycation end-products, REACTIVE oxygen species, ROOT-mean-squares, CARNOSINE, AMINOGUANIDINE

Effect of oral ligustrazine phosphate with cerebroside carnosine on neurological function and serum inflammatory factors among patients with ischemic cerebrovascular disease: a quasi-experimental study

Authors: Qiong Zhao, Zhongyang Liu

Source: European Journal of Medical Research, Vol 30, Iss 1, Pp 1-7 (2025)

Subject Terms: Ligustrazine phosphate tablets, Cerebroside carnosine, Ischemic cerebrovascular illness, Neurological function, Serum inflammatory factors, Medicine

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Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/7725d5b6d7b14c6d81362a122c201369