Computer-aided optimization of carbidopa/levodopa orally disintegrating tablets.

Authors: Qin, Fucheng¹ (AUTHOR), Wan, Congcong¹ (AUTHOR), Zhang, Yuanyuan¹ (AUTHOR) zyy800928@126.com

Source: Drug Development & Industrial Pharmacy. Apr2024, Vol. 50 Issue 4, p331-340. 10p.

Subject Terms: Dopa, Carbidopa, Parkinson's disease, Patient compliance, Response surfaces (Statistics), Independent variables

Efficient Detection of Droxidopa in the Presence of Carbidopa Using a Modified Screen-Printed Graphite Electrode.

Authors: Ahmadi, Sayed Ali¹ (AUTHOR) saahmadi@iauk.ac.ir, Tajik, Somayeh² (AUTHOR)

Source: Topics in Catalysis. May2024, Vol. 67 Issue 9-12, p737-747. 11p.

Subject Terms: *CARBIDOPA, *ELECTROCHEMICAL sensors, *GRAPHITE, *DRINKING water, *ELECTRODES, *CARBON electrodes, *NITRIDES

Metabolite profiling of foslevodopa/foscarbidopa in plasma of healthy human participants by LC‐HRMS indicates no major differences compared to administration of levodopa/carbidopa intestinal gel.

Authors: Savaryn, John P.¹ (AUTHOR), Smith, Richard L.¹ (AUTHOR), Rosebraugh, Matthew¹ (AUTHOR), Neenan, Melina¹ (AUTHOR), Burton, Richard¹ (AUTHOR), Marsh, Kennan¹ (AUTHOR), Wagner, David¹ (AUTHOR) david.wagner@abbvie.com

Source: Pharmacology Research & Perspectives. Apr2024, Vol. 12 Issue 2, p1-11. 11p.

Subject Terms: *CARBIDOPA, *SUBCUTANEOUS infusions, *INTESTINES, *NASOENTERAL tubes, *MASS spectrometry, *DOPA, *MICROBIAL metabolites

Piperine improves levodopa availability in the 6‐OHDA‐lesioned rat model of Parkinson's disease by suppressing gut bacterial tyrosine decarboxylase.

Authors: Hu, Xiaolu¹ (AUTHOR), Yu, Lan¹ (AUTHOR), Li, Yatong¹ (AUTHOR), Li, Xiaoxi² (AUTHOR), Zhao, Yimeng¹ (AUTHOR), Xiong, Lijuan¹ (AUTHOR), Ai, Jiaxuan¹ (AUTHOR), Chen, Qijun³ (AUTHOR), Wang, Xing¹ (AUTHOR), Chen, Xiaoqing¹ (AUTHOR), Ba, Yinying¹ (AUTHOR), Wang, Yaonan⁴ (AUTHOR), Wu, Xia¹ (AUTHOR) wuxia6710@ccmu.edu.cn

Source: CNS Neuroscience & Therapeutics. Feb2024, Vol. 30 Issue 2, p1-14. 14p.

Subject Terms: *PARKINSON'S disease, *CARBIDOPA, *TYROSINE, *DOPA, *ORAL drug administration, *ANIMAL disease models

Quantitative Colorimetric Sensing of Carbidopa in Anti-Parkinson Drugs Based on Selective Reaction with Indole-3-Carbaldehyde.

Authors: Palladino, Pasquale¹ (AUTHOR) pasquale.palladino@unifi.it, Rainetti, Alberto¹ (AUTHOR), Lettieri, Mariagrazia² (AUTHOR), Pieraccini, Giuseppe³ (AUTHOR), Scarano, Simona¹ (AUTHOR), Minunni, Maria⁴ (AUTHOR)

Source: Sensors (14248220). Nov2023, Vol. 23 Issue 22, p9142. 12p.

Subject Terms: *CARBIDOPA, *DOPA, *PARKINSON'S disease, *DRUG standards, *CONDENSATION reactions, *FUNCTIONAL groups, *QUALITY control

Compatibility of Commonly Used Active Pharmaceutical Ingredients in a Ready-to-Use Oral Suspending Vehicle.

Authors: Mansourian, Mercedeh¹ (AUTHOR) mersedeh.mansourian@fagron.com, Dijkers, Eli¹ (AUTHOR), Silva, Carolina C. V.¹ (AUTHOR), Polonini, Hudson C.¹ (AUTHOR) hudson.polonini@fagron.com

Source: Pharmaceutics. Oct2023, Vol. 15 Issue 10, p2388. 11p.

Subject Terms: *HIGH performance liquid chromatography, *CARBIDOPA, *LEVOTHYROXINE, *DOPA

Literature-Based Discovery Predicts Antihistamines Are a Promising Repurposed Adjuvant Therapy for Parkinson's Disease.

Authors: Tandra, Gabriella^1,2 (AUTHOR), Yoone, Amy^1,3 (AUTHOR), Mathew, Rhea^1,4 (AUTHOR), Wang, Minzhi^1,2,4 (AUTHOR), Hales, Chadwick M.⁵ (AUTHOR) cmhales@emory.edu, Mitchell, Cassie S.^1,2,3,6 (AUTHOR) cassie.mitchell@bme.gatech.edu

Source: International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 15, p12339. 17p.

Subject Terms: *PARKINSON'S disease, *CARBIDOPA, *NATURAL language processing, *DOPAMINE, *ANTIHISTAMINES, *ANGIOTENSIN converting enzyme, *KNOWLEDGE graphs

Prediction of drug amount in Parkinson's disease using hybrid machine learning systems and radiomics features.

Authors: Salmanpour, Mohammad R.^1,2,3 (AUTHOR) m.salmanpoor66@gmail.com, Hosseinzadeh, Mahdi^3,4 (AUTHOR), Bakhtiyari, Mahya^3,5 (AUTHOR), Maghsudi, Mehdi⁶ (AUTHOR), Rahmim, Arman^1,2 (AUTHOR)

Source: International Journal of Imaging Systems & Technology. Jul2023, Vol. 33 Issue 4, p1437-1449. 13p.

Subject Terms: *PARKINSON'S disease, *CARBIDOPA, *MACHINE learning, *RADIOMICS, *INSTRUCTIONAL systems, *FEATURE selection, *DRUG delivery systems

Simultaneous sensing of carbidopa and levodopa by a novel strategy based on dual‐emission ratiometric assay of modified carbon dots.

Authors: Abbasi Majd, Sasan¹, Kashanian, Soheila^2,3, kashanian_s@yahoo.com, Shekarbeygi, Zahra⁴, Babaei, Mahsa^5,6

Source: Biotechnology & Applied Biochemistry; Oct2024, Vol. 71 Issue 5, p1032-1043, 12p

This result is not displayed to guests.
Login for full access.

Subcutaneous Levodopa: A New Engine for the Vintage Molecule.

Authors: Poplawska-Domaszewicz, Karolina^1,2 (AUTHOR) karolina.poplawska@usk.poznan.pl, Batzu, Lucia^2,3 (AUTHOR), Falup-Pecurariu, Cristian^2,4,5 (AUTHOR), Chaudhuri, K. Ray^2,3 (AUTHOR)

Source: Neurology & Therapy. Aug2024, Vol. 13 Issue 4, p1055-1068. 14p.

Subject Terms: *CARBIDOPA, *DOPA, *SLEEP quality, *PARKINSON'S disease, *ORAL drug administration, *MOVEMENT disorders, *DYSKINESIAS, *MOLECULES

The Catechol O-Methyltransferase Inhibitor Entacapone in the Treatment of Parkinson's Disease: Personal Reflections on a First-in-Class Drug Development Programme 40 Years On.

Authors: Männistö, Pekka T.¹ (AUTHOR), Keränen, Tapani² (AUTHOR), Reinikainen, Kari J.² (AUTHOR), Hanttu, Anna³ (AUTHOR), Pollesello, Piero⁴ (AUTHOR) piero.pollesello@orionpharma.com

Source: Neurology & Therapy. Aug2024, Vol. 13 Issue 4, p1039-1054. 16p.

Subject Terms: *CARBIDOPA, *PARKINSON'S disease, *DRUG development, *CATECHOL, *CLINICAL trials, *DOPA

Levodopa-Induced Dyskinesia in Parkinson's Disease: Pathogenesis and Emerging Treatment Strategies.

Authors: Kwon, Destany K.^1,2 (AUTHOR), Kwatra, Mohit^1,2 (AUTHOR), Wang, Jing^1,2 (AUTHOR), Ko, Han Seok^1,2 (AUTHOR) hko3@jhmi.edu

Source: Cells (2073-4409). Dec2022, Vol. 11 Issue 23, p3736. 26p.

Subject Terms: *CARBIDOPA, *PARKINSON'S disease, *DYSKINESIAS, *SEROTONIN receptors, *LIFE cycles (Biology), *DOPA

Colorimetric determination of carbidopa in anti-Parkinson drugs based on 4-hydroxy-3-methoxybenzaldazine formation by reaction with vanillin.

Authors: Lettieri, Mariagrazia¹ (AUTHOR), Scarano, Simona¹ (AUTHOR), Palladino, Pasquale¹ (AUTHOR) pasquale.palladino@unifi.it, Minunni, Maria¹ (AUTHOR)

Source: Analytical & Bioanalytical Chemistry. Sep2022, Vol. 414 Issue 23, p6911-6918. 8p.

Subject Terms: *DOPAMINE, *CARBIDOPA, *DOPA, *VANILLIN, *PARKINSON'S disease, *CONDENSATION reactions, *FUNCTIONAL groups

Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson's Disease: Observations and Dilemmas after 10 Years of Real-Life Experience.

Authors: Szász, József Attila^1,2 (AUTHOR) szaszneuro@yahoo.com, Constantin, Viorelia Adelina^1,3 (AUTHOR) vioreliaconstantin@yahoo.com, Orbán-Kis, Károly^1,4 (AUTHOR) istvan.mihaly@umfst.ro, Bancu, Ligia Ariana^5,6 (AUTHOR) ligiabancu@yahoo.com, Bataga, Simona Maria^7,8 (AUTHOR) simona.bataga@umfst.ro, Ciorba, Marius^7,8 (AUTHOR) ciorba_im@yahoo.com, Nagy, Előd^9,10 (AUTHOR) elod.nagy@umfst.ro, Neagoe, Mircea Radu^11,12 (AUTHOR) radu.neagoe@umfst.ro, Mihály, István^4,13 (AUTHOR), Szász, Róbert Máté² (AUTHOR), Kelemen, Krisztina^1,4 (AUTHOR) szabolcs.szatmari@umfst.ro, Simu, Mihaela^14,15 (AUTHOR) simu.mihaela@umft.ro, Szatmári, Szabolcs^1,2 (AUTHOR)

Source: Pharmaceutics. Jun2022, Vol. 14 Issue 6, p1115-N.PAG. 11p.

Subject Terms: *CARBIDOPA, *PARKINSON'S disease, *INTESTINES, *DILEMMA

Reduced Plasma Levodopa Fluctuations with More Frequent Administration of a Novel Carbidopa/Levodopa Functionally Scored Tablet.

Authors: Chase, Thomas N.¹ (AUTHOR), AL‐Sabbagh, Ahmad² (AUTHOR) aal-sabbagh@avionrx.com, Koga, Minako¹ (AUTHOR), Clarence‐Smith, Kathleen¹ (AUTHOR)

Source: Clinical Pharmacology in Drug Development. Apr2024, Vol. 13 Issue 4, p380-388. 9p.

Subject Terms: *CARBIDOPA, *DOPA, *MOTOR ability, *PARKINSON'S disease, *DOPAMINE

Greenness and whiteness appraisal for bioanalysis of quetiapine, levodopa and carbidopa in spiked human plasma by high performance thin layer chromatography.

Authors: Hindam, Finan T.¹ (AUTHOR), Abou Al Alamein, Amal M.² (AUTHOR), Arafa, Reham M.² (AUTHOR) reham.arafa@pharma.cu.edu.eg, Ahmed, Neven¹ (AUTHOR), Eltanany, Basma M.² (AUTHOR)

Source: BMC Chemistry. 10/21/2024, Vol. 18 Issue 1, p1-16. 16p.

Subject Terms: *THIN layer chromatography, *ANALYTICAL chemistry, *CARBIDOPA, *ACETIC acid, *QUETIAPINE

Melanochrome-based colorimetric assay for quantitative detection of levodopa in co-presence of carbidopa and its application to relevant anti-Parkinson drugs.

Authors: Lettieri, Mariagrazia¹ (AUTHOR), Emanuele, Roberta¹ (AUTHOR), Scarano, Simona¹ (AUTHOR), Palladino, Pasquale¹ (AUTHOR) pasquale.palladino@unifi.it, Minunni, Maria¹ (AUTHOR)

Source: Analytical & Bioanalytical Chemistry. Feb2022, Vol. 414 Issue 4, p1713-1722. 10p.

Subject Terms: *DOPA, *CARBIDOPA, *PARKINSON'S disease, *GENERIC drugs, *DIMETHYL sulfoxide, *QUALITY control

Drug-induced Parkinson-like events: a real-world study from 2004 to the first quarter of 2024 based on FAERS.

Authors: Wang, Ke, Chen, Junyan, Huang, Mingquan, Zeng, Xinhao, Ren, Xiaoqun, Liu, Xiuqiong, Tao, Chao, Yang, Liuxuan, Shang, Jinlu, Zhou, Meiling

Source: Frontiers in Pharmacology; 2025, p1-10, 10p

Subject Terms: ANTIPARKINSONIAN agents, DRUG analysis, DRUG side effects, ODDS ratio, DATABASES, CARBIDOPA

Analytical method for simultaneous quantification of levodopa and carbidopa in the injectable oleogel formulation by HPLC

Authors: Deepa D. Nakmode, Souha H. Youssef, Soumyajit Das, Yunmei Song, Sanjay Garg

Source: BMC Chemistry, Vol 19, Iss 1, Pp 1-14 (2025)

Subject Terms: Sodium bisulfite, Drug release, Levodopa, Carbidopa, Green analytical chemistry, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2661-801X

Access URL: https://doaj.org/article/022080e3165f446d8920d93538f9f0dc