High iASPP (PPP1R13L) expression is an independent predictor of adverse clinical outcome in acute myeloid leukemia (AML)

Authors: Mihada Bajrami Saipi, Alessia Ruiba, Marcus Matthias Schittenhelm, Gunnar Blumenstock, Balázs Győrffy, Serena Fazio, Marlon Hafner, Anna-Lena Ahrens, Lara Aldinger, Vanessa Aellig, François G. Kavelaars, César Nombela-Arrieta, Falko Fend, Peter J. M. Valk, Driessen Christoph, Kerstin Maria Kampa-Schittenhelm

Source: Cell Death and Disease, Vol 15, Iss 11, Pp 1-13 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/793637dff01642d6878a7b3b72ca88da

A single‐chain variable fragment‐based bispecific T‐cell activating antibody against CD117 enables T‐cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells

Authors: Laura Volta, Renier Myburgh, Mara Hofstetter, Christian Koch, Jonathan D. Kiefer, Celeste Gobbi, Francesco Manfredi, Kathrin Zimmermann, Philipp Kaufmann, Serena Fazio, Christian Pellegrino, Norman F. Russkamp, Danielle Villars, Mattia Matasci, Monique Maurer, Jan Mueller, Florin Schneiter, Paul Büschl, Niclas Harrer, Jacqueline Mock, Stefan Balabanov, César Nombela‐Arrieta, Timm Schroeder, Dario Neri, Markus G. Manz

Source: HemaSphere, Vol 8, Iss 11, Pp n/a-n/a (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/f01601fd49bb490c81391fc86db051b9

A theory of evolutionary dynamics on any complex population structure reveals stem cell niche architecture as a spatial suppressor of selection

Authors: Yang Ping Kuo, César Nombela-Arrieta, Oana Carja

Source: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7ffff8df87e142208193f217ff8540ae

Bone marrow niches for hematopoietic stem cells

Authors: Ana Luísa Pereira, Serena Galli, César Nombela‐Arrieta

Source: HemaSphere, Vol 8, Iss 8, Pp n/a-n/a (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/03fee2ec76114b889cc5601180bc517e

Biased IL-2 signals induce Foxp3-rich pulmonary lymphoid structures and facilitate long-term lung allograft acceptance in mice

Authors: Yoshito Yamada, Tuan Thanh Nguyen, Daniela Impellizzieri, Katsutaka Mineura, Rintaro Shibuya, Alvaro Gomariz, Martina Haberecker, Jakob Nilsson, César Nombela-Arrieta, Wolfgang Jungraithmayr, Onur Boyman

Source: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/abc4262f8d2243d49d3da3a6fedb78d8

Imaging increased metabolism in the spinal cord in mice after middle cerebral artery occlusion

Authors: Ruiqing Ni, Nadja Straumann, Serana Fazio, Xose Luis Dean-Ben, Georgios Louloudis, Claudia Keller, Daniel Razansky, Simon Ametamey, Linjing Mu, César Nombela-Arrieta, Jan Klohs

Source: Photoacoustics, Vol 32, Iss , Pp 100532- (2023)

Subject Terms: fluorodeoxyglucose (FDG), Ischemic stroke, Metabolism, MSOT, Optoacoustic tomography, Oxygenation, Physics, QC1-999, Acoustics. Sound, QC221-246, Optics. Light, QC350-467

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221359792300085X; https://doaj.org/toc/2213-5979

Access URL: https://doaj.org/article/3965b1b689934382ac6f2fa77a2e5d10

B- and T-cell acute lymphoblastic leukemias evade chemotherapy at distinct sites in the bone marrow

Authors: Malwine J. Barz, Lena Behrmann, Danaëlle Capron, Gabriele Zuchtriegel, Fabio D. Steffen, Leo Kunz, Yang Zhang, Iria Jimenez Vermeerbergen, Blerim Marovca, Moritz Kirschmann, Antonia Zech, César Nombela-Arrieta, Urs Ziegler, Timm Schroeder, Beat Bornhauser, Jean-Pierre Bourquin

Source: Haematologica, Vol 108, Iss 5 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10850; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/92a284cf059b4741ba558a277a2f6d2a

Editorial: The Role of Hematopoietic Progenitors in Immune Regulation and Memory

Authors: Flora Zavala, César Nombela-Arrieta, Moufida Ben Nasr, Paolo Fiorina

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: hematopoietic progenitors, transplantation, immune memory, hematopoietic niche, stromal cells, trained immunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.789139/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/1b0620f984804341b0acb4a60d58abdc

Quantitative spatial analysis of haematopoiesis-regulating stromal cells in the bone marrow microenvironment by 3D microscopy

Authors: Alvaro Gomariz, Patrick M. Helbling, Stephan Isringhausen, Ute Suessbier, Anton Becker, Andreas Boss, Takashi Nagasawa, Grégory Paul, Orcun Goksel, Gábor Székely, Szymon Stoma, Simon F. Nørrelykke, Markus G. Manz, César Nombela-Arrieta

Source: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/47bd299602fb417eaf3eeafe5c30d8ea

Global Transcriptomic Profiling of the Bone Marrow Stromal Microenvironment during Postnatal Development, Aging, and Inflammation

Authors: Patrick M. Helbling, Elena Piñeiro-Yáñez, Rahel Gerosa, Steffen Boettcher, Fátima Al-Shahrour, Markus G. Manz, César Nombela-Arrieta

Source: Cell Reports, Vol 29, Iss 10, Pp 3313-3330.e4 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719314755; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/06f6986902894ccfb19a5144479fbecc

Quantification and three-dimensional microanatomical organization of the bone marrow

Authors: Cesar Nombela-Arrieta, Markus G. Manz

Source: Blood Advances, Vol 1, Iss 6, Pp 407-416 (2017)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952920304092; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/a373029cbf7446df857e1b475e8680a1

S116: CELLULAR AND MOLECULAR MECHANISMS OF EVI1-EXPRESSING MLL-REARRANGED ACUTE MYELOID LEUKEMIA

Authors: Hugues-Etienne Châtel-Soulet, Sabine Juge, Ana Luisa Pereira, Frederik Otzen Bagger, Alexandar Tzankov, Mineo Kurokawa, Athimed El Taher, Jonathan Seguin, César Nombela Arrieta, Juerg Schwaller

Source: HemaSphere, Vol 6, Pp 17-18 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000852280.15271.5c; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/5447b9dc9a0f4978903020c6b2640e97