The C/EBPβ antagonist peptide lucicebtide (ST101) induces macrophage polarization toward a pro-inflammatory phenotype and enhances anti-tumor immune responses

Authors: Claudio Scuoppo, Rick Ramirez, Siok F. Leong, Mark Koester, Zachary F. Mattes, Karen Mendelson, Julia Diehl, Franco Abbate, Erin Gallagher, Lila Ghamsari, Abi Vainstein-Haras, Gene Merutka, Barry J. Kappel, Jim A. Rotolo

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: C/EBPβ, lucicebtide, tumor associate macrophages (TAM), M2-type macrophage, anti-pd 1 immunotherapy, ST101, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1522699/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9a7a54708a7d4878a64b8e8b0156a89e

C/EBPβ in Alzheimer’s disease: An integrative regulator of pathological mechanisms

Authors: Xiaoting Luo, Junyi Liang, Xue Lei, Fengqi Sun, Minghai Gong, Bin Liu, Zhongguang Zhou

Source: Brain Research Bulletin, Vol 221, Iss , Pp 111198- (2025)

Subject Terms: Alzheimer’s disease, C/EBPβ, Neuroinflammation, Lipid metabolism, Aβ metabolism, Tau phosphorylation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0361923025000103; https://doaj.org/toc/1873-2747

Access URL: https://doaj.org/article/0c53a5449e864ada97c0b4b9cfa263ad

Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastinacea

Authors: Shiu-Wen Huang, Ming Jen Hsu, Hsiu-Chen Chen, Rita Meleddu, Simona Distinto, Elias Maccioni, Filippo Cottiglia

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)

Subject Terms: COX-2, benzofurans, Magydaris pastinacea, p38MAPK, JNK, C/EBPβ, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/4ede0bc6e01e44d398ce55962401b995

Short-term cold exposure induces persistent epigenomic memory in brown fat

Authors: Inoue, Shin-ichi ^{1, 10}, Emmett, Matthew J. ^{1, 2, 3, 4, 10}, Lim, Hee-Woong ^{1, 5}, Midha, Mohit ¹, Richter, Hannah J. ^{1, 6}, Celwyn, Isaac J. ¹, Mehmood, Rashid ¹, Chondronikola, Maria ^{7, 8}, Klein, Samuel ⁹, Hauck, Amy K. ¹, Lazar, Mitchell A. ^{1, 11, ∗}

Source: In Cell Metabolism 6 August 2024 36(8):1764-1778

Engineered human osteoarthritic cartilage organoids

Authors: Dönges, Laura ^{a, 1}, Damle, Atharva ^{a, 1}, Mainardi, Andrea ^a, Bock, Thomas ^b, Schönenberger, Monica ^c, Martin, Ivan ^{a, ⁎}, Barbero, Andrea ^a

Source: In Biomaterials July 2024 308

C/EBPβ Regulates HIF-1α-Driven Invasion of Non-Small-Cell Lung Cancer Cells

Authors: Seung Hee Seo, Ji Hae Lee, Eun Kyung Choi, Seung Bae Rho, Kyungsil Yoon

Source: Biomolecules, Vol 15, Iss 1, p 36 (2024)

Subject Terms: C/EBPβ, hypoxia, HIF-1α, metastasis, non-small-cell lung cancer, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/15/1/36; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/731975892c074012b6652427ffeac2b2

Hypoxia/inflammation-induced upregulation of HIF-1α and C/EBPβ promotes nephroblastoma cell EMT by improving HOXA11-AS transcription

Authors: Zhu, Shibo ^⁎, Zhou, Rui, Tang, Xiangliang, Fu, Wen, Jia, Wei

Source: In Heliyon 30 March 2024 10(6)

Exercise training attenuates angiotensin II-induced cardiac fibrosis by reducing POU2F1 expression

Authors: Na Feng, Haiyi Yu, Yueshen Wang, Youyi Zhang, Han Xiao, Wei Gao

Source: Journal of Sport and Health Science, Vol 12, Iss 4, Pp 464-476 (2023)

Subject Terms: AMPK, C/EBPβ, Cardiac fibrosis, Exercise, POU2F1, Sports, GV557-1198.995, Sports medicine, RC1200-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095254622001041; https://doaj.org/toc/2095-2546

Access URL: https://doaj.org/article/3f1446fbcec4401894d48efda2cef65c

C/EBPβ expression decreases in cervical cancer and leads to tumorigenesis

Authors: Haichen Long, Yangyang Li, Huijuan Wang, Bingxuan Guo, Shuyan Song, Xiangyi Zhe, Hongtao Li, Dongmei Li, Renfu Shao, Zemin Pan

Source: BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)

Subject Terms: C/EBPβ, Gene expression, Cervical cancer, Proliferation, Invasion, Migration, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/8ed55b28695a45a49968b8e6c2661b53

C/EBPβ Promotes LPS-Induced IL-1β Transcription and Secretion in Alveolar Macrophages via NOD2 Signaling

Authors: Luo Y, Ge P, Wen H, Zhang Y, Liu J, Dong X, Lan B, Zhang G, Yang Q, Chen H

Source: Journal of Inflammation Research, Vol Volume 15, Pp 5247-5263 (2022)

Subject Terms: c/ebpβ, alveolar macrophage, rna-seq, nod-like receptor signaling pathway, il-1β，virtual screening, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/cebp-promotes-lps-induced-il-1-transcription-and-secretion-in-alveolar-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Access URL: https://doaj.org/article/b9e7b79ef7a2483d93fb662bde6408fe

PDIA3P1 promotes Temozolomide resistance in glioblastoma by inhibiting C/EBPβ degradation to facilitate proneural-to-mesenchymal transition

Authors: Zijie Gao, Jianye Xu, Yang Fan, Yanhua Qi, Shaobo Wang, Shulin Zhao, Xing Guo, Hao Xue, Lin Deng, Rongrong Zhao, Chong Sun, Ping Zhang, Gang Li

Source: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-21 (2022)

Subject Terms: PDIA3P1, Temozolomide, Proneural-to-mesenchymal transition, Glioma stem cells, C/EBPβ, MDM2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/f058aa00a20a45e7924f05ebdf289b1a

C/EBPβ-LIP mediated activation of the malate-aspartate shuttle sensitizes cells to glycolysis inhibition

Authors: Tobias Ackermann, Hidde R. Zuidhof, Christine Müller, Gertrud Kortman, Martijn G.S. Rutten, Mathilde J.C. Broekhuis, Mohamad Amr Zaini, Götz Hartleben, Cornelis F. Calkhoven

Source: Molecular Metabolism, Vol 72, Iss , Pp 101726- (2023)

Subject Terms: C/EBPβ, Malate-aspartate shuttle, Glycolysis, NAD+, Cancer, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877823000601; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/e7845cf038514e76a8bcc1de52b05e93

HIPK1 Inhibition Protects against Pathological Cardiac Hypertrophy by Inhibiting the CREB‐C/EBPβ Axis

Authors: Yihua Bei, Yujiao Zhu, Meng Wei, Mingming Yin, Lin Li, Chen Chen, Zhenzhen Huang, Xuchun Liang, Juan Gao, Jianhua Yao, Petra H. van derKraak, Aryan Vink, Zhiyong Lei, Yuxiang Dai, Huihua Chen, Yueyang Liang, Joost PG Sluijter, Junjie Xiao

Source: Advanced Science, Vol 10, Iss 18, Pp n/a-n/a (2023)

Subject Terms: C/EBPβ, cardiomyocytes, CREB, HIPK1, pathological hypertrophy, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/bde7fa404ab446fc9d2fb725485b65a0

Emerging functions of C/EBPβ in breast cancer

Authors: Megan G. Matherne, Emily S. Phillips, Samuel J. Embrey, Caitlin M. Burke, Heather L. Machado

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: C/EBPβ, breast cancer, transcription factor, immune cells, gene regulation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1111522/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/b96b09612f8a473890d8ea6e75c0eb46

Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice

Authors: Yiyi Li, Hongyu Chen, Jianhao Wang, Jiabei Wang, Xuan Niu, Chao Wang, Dongdong Qin, Fang Li, Yamei Wang, Jing Xiong, Songyan Liu, Liqin Huang, Xi Zhang, Feng Gao, Dandan Gao, Mingxia Fan, Xuan Xiao, Zhi-Hao Wang

Source: Frontiers in Molecular Neuroscience, Vol 15 (2022)

Subject Terms: high-fat diet, depression, transcription factor, C/EBPβ, inflammation, BDNF, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2022.1068164/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/cb7bea7754d6439eb232b0c4c0c0e051

β-(4-fluorobenzyl) Arteannuin B induced interaction of ATF-4 and C/EBPβ mediates the transition of breast cancer cells from autophagy to senescence

Authors: Khalid Bashir Mir, Mir Mohd Faheem, Syed Mudabir Ahmad, Javeed Ur Rasool, Tanzeeba Amin, Souneek Chakraborty, Madhulika Bhagat, Zabeer Ahmed, Asif Ali, Anindya Goswami

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: arteannuin B, ATF-4, C/EBPβ, breast cancer, senescence, autophagy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.1013500/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/32d5fd12f5664cc2969f9463ff31773b

C/EBPβ converts bovine fibroblasts to adipocytes without hormone cocktail induction

Authors: Gong Cheng, Sayed Haidar Abbas Raza, Rajwali Khan, Hong Wang, Abdullah F. Shater, Zuhair M. Mohammedsaleh, Li Wang, Yuan Tian, Feng Long, Linsen Zan

Source: Electronic Journal of Biotechnology, Vol 52, Iss , Pp 67-75 (2021)

Subject Terms: Adipogenesis, Adipogenic genes, C/EBPβ, Cattle, Fibroblasts, Fibrogenesis, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0717345821000233; https://doaj.org/toc/0717-3458

Access URL: https://doaj.org/article/cc1cf8dba5b74a9687d45d17250026ed

KDM6B promotes ESCC cell proliferation and metastasis by facilitating C/EBPβ transcription

Authors: Mei Qin, Fei Han, Jian Wu, Feng-xia Gao, Yuan Li, De-xin Yan, Xue-mei He, Yang Long, Xiao-ping Tang, De-lian Ren, Yan Gao, Tian-yang Dai

Source: BMC Cancer, Vol 21, Iss 1, Pp 1-16 (2021)

Subject Terms: ESCC, KDM6B, H3K27me3, C/EBPβ, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/616bf2b52bff4ad6b2dbef347c80ebcb

Three chemotypes of thyme (Thymus vulgaris L.) essential oil and their main compounds affect differently the IL-6 and TNFα cytokine secretions of BV-2 microglia by modulating the NF-κB and C/EBPβ signalling pathways

Authors: Györgyi Horváth, Adrienn Horváth, Gréta Reichert, Andrea Böszörményi, Katalin Sipos, Edina Pandur

Source: BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-14 (2021)

Subject Terms: Essential oil, Inflammation, Microglia, Cytokine, NF-κB, C/EBPβ, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/1e2a61bf8d684fd88570ee2e3d30cea2

C/EBPβ regulates the JAK/STAT signaling pathway in triple‐negative breast cancer

Authors: Shu Wang, Dian Xia, Xianzhi Wang, Haowei Cao, Chaoshen Wu, Zhaoran Sun, Daoyong Zhang, Hao Liu

Source: FEBS Open Bio, Vol 11, Iss 4, Pp 1250-1258 (2021)

Subject Terms: C/EBPβ, JAK, STAT, Triple‐Negative Breast Cancer, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2211-5463

Access URL: https://doaj.org/article/114ebe428a90493782e5e7bb6f3ee64a