Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance

Authors: Clanchy, Felix IL., Borghese, Federica, Bystrom, Jonas, Balog, Attila, Penn, Henry, Hull, Dobrina N., Mageed, Rizgar A., Taylor, Peter C., Williams, Richard O.

Source: In Journal of Autoimmunity September 2024 148

Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression

Authors: Clanchy, Felix I.L., Borghese, Federica, Bystrom, Jonas, Balog, Attila, Penn, Henry, Taylor, Peter C., Stone, Trevor W., Mageed, Rizgar A., Williams, Richard O.

Source: In Journal of Autoimmunity April 2022 128

TLR expression profiles are a function of disease status in rheumatoid arthritis and experimental arthritis

Authors: Clanchy, Felix I.L., Borghese, Federica, Bystrom, Jonas, Balog, Attila, Penn, Henry, Hull, Dobrina N., Wells, Graham M.A., Kiriakidis, Serafim, Taylor, Peter C., Sacre, Sandra M., Williams, Lynn M., Stone, Trevor W., Mageed, Rizgar A., Williams, Richard O.

Source: In Journal of Autoimmunity March 2021 118

TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases

Authors: Bystrom, Jonas, Clanchy, F.I., Taher, Taher E., Mangat, Pam, Jawad, Ali S., Williams, Richard O., Mageed, Rizgar A.

Source: In Cytokine January 2018 101:4-13

CYP450-derived oxylipins mediate inflammatory resolution

Authors: Gilroy, Derek W., Edin, Matthew L., De Maeyer, Roel P. H., Bystrom, Jonas, Newson, Justine, Lih, Fred B., Stables, Melanie, Zeldin, Darryl C., Bishop-Bailey, David

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Jun 01. 113(23), E3240-E3249.

Access URL: https://www.jstor.org/stable/26470241

Transcriptomic analyses of murine resolution-phase macrophages

Authors: Stables, Melanie J., Shah, Sonia, Camon, Evelyn B., Lovering, Ruth C., Newson, Justine, Bystrom, Jonas, Farrow, Stuart, Gilroy, Derek W.

Source: In Blood 22 December 2011 118(26):e192-e208

Emerging roles of peroxisome proliferator-activated receptor-β/δ in inflammation

Authors: Bishop-Bailey, David, Bystrom, Jonas

Source: In Pharmacology and Therapeutics 2009 124(2):141-150

Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP

Authors: Bystrom, Jonas, Evans, Ian, Newson, Justine, Stables, Melanie, Toor, Iqbal, van Rooijen, Nico, Crawford, Mark, Colville-Nash, Paul, Farrow, Stuart, Gilroy, Derek W.

Source: In Blood 15 November 2008 112(10):4117-4127

Novel biphasic role for lymphocytes revealed during resolving inflammation

Authors: Rajakariar, Ravindra, Lawrence, Toby, Bystrom, Jonas, Hilliard, Mark, Colville-Nash, Paul, Bellingan, Geoff, Fitzgerald, Desmond, Yaqoob, Muhammad M., Gilroy, Derek W.

Source: In Blood 15 April 2008 111(8):4184-4192

Metabolic requirements of Th17 cells and of B cells: Regulation and defects in health and in inflammatory diseases.

Authors: Bystrom, Jonas, Taher, Taher E., Henson, Sian M., Gould, David J., Mageed, Rizgar A.

Source: Frontiers in Immunology; 10/14/2022, Vol. 13, p01-16, 16p

Subject Terms: B cells, T helper cells, CELLULAR control mechanisms, IMMUNOGLOBULIN producing cells, ANTIGEN presenting cells, EPIGENOMICS, HUMORAL immunity

Novel Eosinophil Cationic Proteins used in the Treatement of Asthematic and Allergic Disorders

Analysing the eosinophil cationic protein - a clue to the function of the eosinophil granulocyte

Authors: Bishop-Bailey David, Amin Kawa, Bystrom Jonas

Source: Respiratory Research, Vol 12, Iss 1, p 10 (2011)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://respiratory-research.com/content/12/1/10; https://doaj.org/toc/1465-9921

Access URL: https://doaj.org/article/84d68c9deec24a2583f52532e7efda23

Harnessing the Therapeutic Potential of Th17 Cells.

Authors: Bystrom, Jonas¹ j.bystrom@qmul.ac.uk, Taher, Taher E.¹ t.e.i.taher@qmul.ac.uk, Muhyaddin, M. Sherwan² sherwan_10@hotmail.com, Clanchy, Felix I.³ felix.clanchy@kennedy.ox.ac.uk, Mangat, Pamela⁴ pamela.mangat@nhs.net, Jawad, Ali S.⁵ alismjawad1@hotmail.com, Williams, Richard O.³ richard.williams@kennedy.ox.ac.uk, Mageed, Rizgar A.¹ r.a.mageed@qmul.ac.uk

Source: Mediators of Inflammation. 5/26/2015, Vol. 2015, p1-11. 11p.

Subject Terms: *T helper cells, *EXTRACELLULAR matrix, *INTERLEUKIN-17, *AUTOIMMUNITY, *TRANSCRIPTION factors, *PSORIATIC arthritis

Inducible CYP2J2 and Its Product 11,12-EET Promotes Bacterial Phagocytosis: A Role for CYP2J2 Deficiency in the Pathogenesis of Crohn’s Disease?

Authors: Bystrom, Jonas¹, Thomson, Scott J.², Johansson, Jörgen³, Edin, Matthew L.⁴, Zeldin, Darryl C.⁴, Gilroy, Derek W.⁵, Smith, Andrew M.⁵, Bishop-Bailey, David² dbishopbailey@rvc.ac.uk

Source: PLoS ONE. Sep2013, Vol. 8 Issue 9, p1-8. 8p.

Subject Terms: *PHAGOCYTOSIS, *CROHN'S disease, *INFLAMMATION, *GENE expression in bacteria, *MONOCYTES, *ANTI-inflammatory agents, *MACROPHAGES

TNFα inhibitors reduce bone loss in rheumatoid arthritis independent of clinical response by reducing osteoclast precursors and IL-20.

Authors: Al-Bogami, Mohammed¹, Bystrom, Jonas¹, Clanchy, Felix², Taher, Taher E¹, Mangat, Pamela³, Williams, Richard O², Jawad, Ali S⁴, Mageed, Rizgar A¹ r.a.mageed@qmul.ac.uk

Source: Rheumatology. Feb2021, Vol. 60 Issue 2, p947-957. 11p.

Subject Terms: *ANTI-inflammatory agents, *BIOMARKERS, *CYTOKINES, *ENZYME-linked immunosorbent assay, *FLOW cytometry, *GENE expression, *INTERLEUKINS, *MEMBRANE proteins, *MICROSCOPY, *OSTEOCLASTS, *RHEUMATOID arthritis, *BONE density, *TREATMENT effectiveness, *PHOTON absorptiometry, *PHARMACODYNAMICS

Th17 Lymphocytes in Respiratory Syncytial Virus Infection.

Authors: Bystrom, Jonas¹ j.bystrom@qmul.ac.uk, Al-Adhoubi, Nasra² nasrak2004@yahoo.com, Al-Bogami, Mohammed¹ m.al-bogami@qmul.ac.uk, Jawad, Ali S.² alismjawad1@hotmail.com, Mageed, Rizgar A.¹ r.a.mageed@qmul.ac.uk

Source: Viruses (1999-4915). Mar2013, Vol. 5 Issue 3, p777-791. 15p. 1 Diagram, 1 Chart.

Subject Terms: *T helper cells, *LYMPHOCYTES, *RESPIRATORY syncytial virus, *RESPIRATORY syncytial virus infections, *IMMUNE response, *CD8 antigen

Endogenous Epoxygenases Are Modulators of Monocyte/ Macrophage Activity.

Authors: Bystrom, Jonas¹, Wray, Jessica A.², Sugden, Mary C.³, Holness, Mark J.³, Swales, Karen E.⁴, Warner, Timothy D.¹, Edin, Matthew L.⁵, Zeldin, Darryl C.⁵, Gilroy, Derek W.⁶, Bishop-Bailey, David¹ d.bishop-bailey@qmul.ac.uk

Source: PLoS ONE. 2011, Vol. 6 Issue 10, p1-8. 8p.

Subject Terms: *ARACHIDONIC acid, *CYCLOOXYGENASES, *LIPOXYGENASES, *MACROPHAGES, *PEROXISOMES, *MESSENGER RNA

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Evidence for eosinophil and IL-17 mediated inflammation in allergic rhinitis.

Authors: Amin, Kawa, Issa, Sulaf Mosa, Ali, Kosar Mohammad, Aziz, Muaid Ismiel, Hama Amieen, Huner Mohamed, Bystrom, Jonas, Janson, Christer

Source: Clinical & Molecular Allergy; 4/4/2020, Vol. 18 Issue 1, p1-7, 7p, 2 Charts, 3 Graphs

Subject Terms: RESPIRATORY allergy diagnosis, RHINITIS treatment, AGE distribution, BIOMARKERS, BLOOD proteins, ENZYME-linked immunosorbent assay, EOSINOPHILS, FLOW cytometry, IMMUNOGLOBULINS, INTERLEUKINS, RESPIRATORY allergy, RHINITIS, SEX distribution, LEUKOCYTE count