Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation.

Authors: Carter-Cusack, Dylan¹, david.hume@uq.edu.au, Huang, Stephen¹, Keshvari, Sahar¹, Patkar, Omkar¹, Sehgal, Anuj¹, Allavena, Rachel², Byrne, Robert A. J.³, Morgan, B. Paul³, Bush, Stephen J.⁴, Summers, Kim M.¹, Irvine, Katharine M.¹, Hume, David A.¹, d.cartercusack@student.uq.edu.au

Source: PLoS Genetics; 1/27/2025, Vol. 21 Issue 1, p1-39, 39p

Terminal complement pathway activation drives synaptic loss in Alzheimer's disease models.

Authors: Carpanini, Sarah M., Torvell, Megan, Bevan, Ryan J., Byrne, Robert A. J., Daskoulidou, Nikoleta, Saito, Takashi, Saido, Takaomi C., Taylor, Philip R., Hughes, Timothy R., Zelek, Wioleta M., Morgan, B. Paul

Source: Acta Neuropathologica Communications; 7/6/2022, Vol. 10 Issue 1, p1-16, 16p

Subject Terms: ALZHEIMER'S disease, COMPLEMENT activation, MEDICAL model, MYASTHENIA gravis, MYONEURAL junction, GENE knockout, DENDRITIC spines

Novel Monoclonal Antibodies Against Mouse C1q: Characterisation and Development of a Quantitative ELISA for Mouse C1q.

Authors: Byrne, Robert A. J., Torvell, Megan, Daskoulidou, Nikoleta, Fathalla, Dina, Kokkali, Eirini, Carpanini, Sarah M., Morgan, B. Paul

Source: Molecular Neurobiology; Sep2021, Vol. 58 Issue 9, p4323-4336, 14p

Genetic Insights into the Impact of Complement in Alzheimer's Disease.

Authors: Torvell, Megan, Carpanini, Sarah M., Daskoulidou, Nikoleta, Byrne, Robert A. J., Sims, Rebecca, Morgan, B. Paul

Source: Genes; Dec2021, Vol. 12 Issue 12, p1990-1990, 1p

Subject Terms: ALZHEIMER'S disease, GENOME-wide association studies, ETIOLOGY of diseases, COMPLEMENT activation, GENETIC variation, SYNAPSES