Dysregulation of airway and systemic interferon responses promotes asthma exacerbations in urban children

Authors: Gaberino, Courtney L. ^{a, ∗}, Altman, Matthew C. ^b, Gill, Michelle A. ^c, Bacharier, Leonard B. ^d, Gruchalla, Rebecca S. ^e, O’Connor, George T. ^f, Kumar, Rajesh ^g, Khurana Hershey, Gurjit K. ^h, Kattan, Meyer ⁱ, Liu, Andrew H. ^j, Teach, Stephen J. ^k, Zoratti, Edward M. ^l, Becker, Patrice M. ^m, Togias, Alkis ^m, Visness, Cynthia ⁿ, Gern, James E. ^a, Busse, William W. ^a, Jackson, Daniel J. ^a

Source: In The Journal of Allergy and Clinical Immunology December 2024

Identification of bronchial epithelial genes associated with type 2 eosinophilic inflammation in asthma

Authors: Esnault, Stephane ^{a, d}, Dill-McFarland, Kimberly A. ^e, Altman, Matthew C. ^{e, f}, Rosenkranz, Melissa A. ^{b, c}, Jarjour, Nizar N. ^a, Busse, William W. ^{a, ∗}

Source: In The Journal of Allergy and Clinical Immunology December 2024

Rhinoconjunctivitis symptoms in children and adolescents with asthma: Longitudinal clustering analysis

Authors: Togias, Alkis ^{a, ∗}, Gergen, Peter J. ^a, Liu, Andrew H. ^b, Kim, Haejin ^c, Wood, Robert A. ^d, O’Connor, George T. ^e, Makhija, Melanie ^f, Khurana Hershey, Gurjit K. ^g, Kercsmar, Carolyn M. ^g, Gruchalla, Rebecca S. ^h, Lamm, Carin ⁱ, Bacharier, Leonard B. ^j, Patel, Shilpa J. ^k, Gern, James E. ^l, Jackson, Daniel J. ^l, Visness, Cynthia M. ^m, Calatroni, Agustin ^m, Busse, William W. ^l

Source: In The Journal of Allergy and Clinical Immunology December 2024

Dupilumab Induces Long-Term On-Treatment Clinical Remission in Patients With Type 2 Asthma

Authors: Pavord, Ian D. ^{a, ∗}, Rabe, Klaus F. ^b, Israel, Elliot ^{c, d}, Szefler, Stanley J. ^e, Brusselle, Guy ^f, Pandit-Abid, Nami ^g, Altincatal, Arman ^h, Chen, Zhen ⁱ, Amin, Nikhil ^{i, ∗}, Khan, Asif H. ^j, Lederer, David J. ⁱ, Zhang, Yi ⁱ, Rowe, Paul J. ^g, Deniz, Yamo ⁱ, Radwan, Amr ⁱ, Jacob-Nara, Juby A. ^g, Busse, William W. ^k

Source: In The Journal of Allergy and Clinical Immunology: In Practice January 2025 13(1):132-142

The role of biologics in inducing remission in asthma

Authors: Busse, William W.

Source: In Annals of Allergy, Asthma & Immunology January 2025 134(1):19-30

Regional brain structural alterations in reward and salience networks in asthma

Authors: Carrol, Danielle ^a, Busse, William W. ^b, Frye, Corrina J. ^c, Klaus, Danika R. ^b, Bach, Julia C. ^b, Floerke, Heather ^b, Bendlin, Barbara B. ^d, Zetterberg, Henrik ^{d, e, f, g, h, i}, Blennow, Kaj ^{e, f, j, k}, Heslegrave, Amanda ^{f, g}, Hoel, Rachel ^a, Rosenkranz, Melissa A. ^{a, l, ⁎}

Source: In Brain Behavior and Immunity May 2025 126:80-97

Salience network resting state functional connectivity during airway inflammation in asthma: A feature of mental health resilience?

Authors: Laubacher, Claire ^{a, 1}, Imhoff-Smith, Theodore P. ^{b, 1}, Klaus, Danika R. ^c, Frye, Corrina J. ^d, Esnault, Stephane ^{c, e}, Busse, William W. ^c, Rosenkranz, Melissa A. ^{a, f, ⁎}

Source: In Brain Behavior and Immunity November 2024 122:9-17

Home and school pollutant exposure, respiratory outcomes, and influence of historical redlining

Authors: Jung, Kyung Hwa, Argenio, Kira L., Jackson, Daniel J., Miller, Rachel L., Perzanowski, Matthew S., Rundle, Andrew G., Bacharier, Leonard B., Busse, William W., Cohen, Robyn T., Visness, Cynthia M., Gill, Michelle A., Gruchalla, Rebecca S., Hershey, Gurjit K., Kado, Rachel K., Sherenian, Michael G., Liu, Andrew H., Makhija, Melanie M., Pillai, Dinesh K., Rivera-Spoljaric, Katherine, Gergen, Peter J., Altman, Matthew C., Sandel, Megan T., Sorkness, Christine A., Kattan, Meyer, Lovinsky-Desir, Stephanie

Source: In The Journal of Allergy and Clinical Immunology November 2024 154(5):1159-1168

A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy

Authors: Zoratti, Edward, Wood, Robert, Pomés, Anna, Da Silva Antunes, Ricardo, Altman, Matthew C., Benson, Basilin, Wheatley, Lisa M., Cho, Kate, Calatroni, Agustin, Little, Frederic F., Pongracic, J., Makhija, Melanie, Khurana Hershey, Gurjit K., Sherenian, Michael G., Rivera-Spoljaric, Katherine, Stokes, Jeffrey R., Gill, Michelle A., Gruchalla, Rebecca S., Chambliss, Jeffrey, Liu, Andrew H., Kattan, Meyer, Busse, Paula J., Bacharier, Leonard B., Sheehan, William, Kim, Haejin., Glesner, Jill, Gergen, Peter J., Togias, Alkis, Baucom, Jessica L., Visness, Cynthia M., Sette, Alessandro, Busse, William W., Jackson, Daniel J.

Source: In The Journal of Allergy and Clinical Immunology September 2024 154(3):735-744

Alzheimer incidence and prevalence with and without asthma: A Medicare cohort study

Authors: Bartels, Christie M., Chen, Yi, Powell, W. Ryan, Rosenkranz, Melissa A., Bendlin, Barbara B., Kramer, Joseph, Busse, William W., Kind, Amy

Source: In The Journal of Allergy and Clinical Immunology August 2024 154(2):498-502

Activated sputum eosinophils associated with exacerbations in children on mepolizumab

Authors: Wilson, Gabriella E., Knight, James, Liu, Qing, Shelar, Ashish, Stewart, Emma, Wang, Xiaomei, Yan, Xiting, Sanders, Joshua, Visness, Cynthia, Gill, Michelle, Gruchalla, Rebecca, Liu, Andrew H., Kattan, Meyer, Khurana Hershey, Gurjit K., Togias, Alkis, Becker, Patrice M., Altman, Matthew C., Busse, William W., Jackson, Daniel J., Montgomery, Ruth R., Chupp, Geoffrey L.

Source: In The Journal of Allergy and Clinical Immunology August 2024 154(2):297-307

Gene-based association study of rare variants in children of diverse ancestries implicates TNFRSF21 in the development of allergic asthma

Authors: Clay, Selene, Alladina, Jehan, Smith, Neal P., Visness, Cynthia M., Wood, Robert A., O’Connor, George T., Cohen, Robyn T., Khurana Hershey, Gurjit K., Kercsmar, Carolyn M., Gruchalla, Rebecca S., Gill, Michelle A., Liu, Andrew H., Kim, Haejin, Kattan, Meyer, Bacharier, Leonard B., Rastogi, Deepa, Rivera-Spoljaric, Katherine, Robison, Rachel G., Gergen, Peter J., Busse, William W., Villani, Alexandra-Chloe, Cho, Josalyn L., Medoff, Benjamin D., Gern, James E., Jackson, Daniel J., Ober, Carole, Dapas, Matthew

Source: In The Journal of Allergy and Clinical Immunology March 2024 153(3):809-820

Resting state functional connectivity changes following mindfulness-based stress reduction predict improvements in disease control for patients with asthma

Authors: Laubacher, Claire, Kral, Tammi R.A., Imhoff-Smith, Ted, Klaus, Danika R., Goldman, Robin I., Sachs, Jane, Davidson, Richard J., Busse, William W., Rosenkranz, Melissa A.

Source: In Brain Behavior and Immunity January 2024 115:480-493

Molecular pathways underlying lung-brain axis signaling in asthma: Relevance for psychopathology and neuroinflammation

Authors: Dill-McFarland, Kimberly A., Altman, Matthew C., Esnault, Stephane, Jarjour, Nizar N., Busse, William W., Rosenkranz, Melissa A.

Source: In The Journal of Allergy and Clinical Immunology January 2024 153(1):111-121

Efficacy of dupilumab in patients with uncontrolled, moderate‐to‐severe asthma with fungal sensitization

Authors: Corren, Jonathan, Hanania, Nicola A., Busse, William W., Sher, Lawrence D., Altincatal, Arman, Hardin, Megan, Mannent, Leda P., Amin, Nikhil, Lederer, David J., Soler, Xavier, Jacob‐Nara, Juby A., Rowe, Paul J., Deniz, Yamo

Source: Clinical & experimental allergy. 53(10):1020-1030

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195057778.0x000001&indx=1&recIds=ETOCvdc_100195057778.0x000001

Dupilumab improves long‐term outcomes in patients with uncontrolled, moderate‐to‐severe GINA‐based type 2 asthma, irrespective of allergic status

Authors: Rabe, Klaus F., Pavord, Ian D., Busse, William W., Chupp, Geoffrey L., Izuhara, Kenji, Altincatal, Arman, Gall, Rebecca, Pandit‐Abid, Nami, Deniz, Yamo, Rowe, Paul J., Jacob‐Nara, Juby A., Radwan, Amr

Source: Allergy. 78(8):2148-2156

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189375326.0x000001&indx=1&recIds=ETOCvdc_100189375326.0x000001

Consequences of severe asthma exacerbations

Authors: Busse, William W.

Source: Current opinion in allergy and clinical immunology. 23(1):44-50

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178458759.0x000001&indx=1&recIds=ETOCvdc_100178458759.0x000001

Dupilumab efficacy in high sleep disturbance management among patients with type 2 asthma

Authors: Maspero, Jorge F., Shafazand, Shirin, Cole, Jeremy, Pavord, Ian D., Busse, William W., Msihid, Jérôme, Gall, Rebecca, Soler, Xavier, Radwan, Amr, Khan, Asif H., de Prado Gómez, Lucia, Jacob-Nara, Juby A.

Source: In Respiratory Medicine November 2023 218

Safety and Efficacy of Dexpramipexole in Eosinophilic Asthma (EXHALE): A randomized controlled trial

Authors: Siddiqui, Salman, Wenzel, Sally E., Bozik, Michael E., Archibald, Donald G., Dworetzky, Steven I., Mather, James L., Killingsworth, Randall, Ghearing, Natasha, Schwartz, Justin T., Ochkur, Sergei I., Jacobsen, Elizabeth A., Busse, William W., Panettieri, Reynold A., Prussin, Calman

Source: In The Journal of Allergy and Clinical Immunology November 2023 152(5):1121-1130

The Unified Airway Hypothesis: Evidence From Specific Intervention With Anti–IL-5 Biologic Therapy

Authors: Bachert, Claus, Luong, Amber U., Gevaert, Philippe, Mullol, Joaquim, Smith, Steven G., Silver, Jared, Sousa, Ana R., Howarth, Peter H., Benson, Victoria S., Mayer, Bhabita, Chan, Robert H., Busse, William W.

Source: In The Journal of Allergy and Clinical Immunology: In Practice September 2023 11(9):2630-2641