PhosphoLipidome Alteration Induced by Clostridioides difficile Toxin B in Enteric Glial Cells.

Authors: Buratta, Sandra^1,2 (AUTHOR) sandra.buratta@unipg.it, Urbanelli, Lorena^1,2 (AUTHOR) lorena.urbanelli@unipg.it, Pellegrino, Roberto Maria¹ (AUTHOR) roberto.pellegrino@unipg.it, Alabed, Husam B. R.¹ (AUTHOR) husambr.alabed@dottorandi.unipg.it, Latella, Raffaella¹ (AUTHOR) raffaella.latella@dottorandi.unipg.it, Cerrotti, Giada¹ (AUTHOR) giada.cerrotti@dottorandi.unipg.it, Emiliani, Carla^1,2 (AUTHOR) carla.emiliani@unipg.it, Bassotti, Gabrio^3,4 (AUTHOR) gabassot@gmail.com, Spaterna, Andrea⁵ (AUTHOR), Marconi, Pierfrancesco⁶ (AUTHOR) pierfrancesco.marconi@outlook.it, Fettucciari, Katia⁶ (AUTHOR) katia.fettucciari@unipg.it

Source: Cells (2073-4409). Jul2024, Vol. 13 Issue 13, p1103. 16p.

Subject Terms: *CELL metabolism, *LIPID metabolism, *NEUROGLIA, *CLOSTRIDIOIDES difficile, *CELL cycle

Evidence of Lysosomal β-Hexosaminidase Enzymatic Activity Associated with Extracellular Vesicles: Potential Applications for the Correction of Sandhoff Disease.

Authors: Calzoni, Eleonora¹, eleonora.calzoni@unipg.it, Cerrotti, Giada¹, giada.cerrotti@dottorandi.unipg.it, Sagini, Krizia¹, krizia.sagini@ous-research.no, Delo, Federica¹, fdelo@biostherapy.it, Buratta, Sandra^1,2, sandra.buratta@unipg.it, Pellegrino, Roberto Maria¹, roberto.pellegrino@unipg.it, Alabed, Husam B. R.¹, husambr.alabed@dottorandi.unipg.it, Fratini, Federica³, federica.fratini@iss.it, Emiliani, Carla^1,2, carla.emiliani@unipg.it, Urbanelli, Lorena^1,2, lorena.urbanelli@unipg.it

Source: Journal of Functional Biomaterials; Jun2024, Vol. 15 Issue 6, p153, 13p

Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract

Authors: Chiaradia, Elisabetta, Sansone, Anna, Ferreri, Carla, Tancini, Brunella, Latella, Raffaella, Tognoloni, Alessia, Gambelunghe, Angela, dell’Omo, Marco, Urbanelli, Lorena, Giovagnoli, Stefano, Pellegrino, Roberto Maria, Cerrotti, Giada, Emiliani, Carla, Buratta, Sandra

Source: In European Journal of Cell Biology March 2023 102(1)

Parallel single-cell metabolic analysis and extracellular vesicle profiling reveal vulnerabilities with prognostic significance in acute myeloid leukemia.

Authors: Forte, Dorian, Pellegrino, Roberto Maria, Falvo, Paolo, Garcia-Gonzalez, Paulina, Alabed, Husam B. R., Maltoni, Filippo, Lombardi, Davide, Bruno, Samantha, Barone, Martina, Pasini, Federico, Fabbri, Francesco, Vannini, Ivan, Donati, Benedetta, Cristiano, Gianluca, Sartor, Chiara, Ronzoni, Simona, Ciarrocchi, Alessia, Buratta, Sandra, Urbanelli, Lorena, Emiliani, Carla

Source: Nature Communications; 12/30/2024, Vol. 15 Issue 1, p1-19, 19p

Subject Terms: ACUTE myeloid leukemia, METABOLIC reprogramming, EXTRACELLULAR vesicles, OXIDATION of glucose, PROGNOSIS

Plant-Derived Extracellular Vesicles: Natural Nanocarriers for Biotechnological Drugs.

Authors: Calzoni, Eleonora, Bertoldi, Agnese, Cusumano, Gaia, Buratta, Sandra, Urbanelli, Lorena, Emiliani, Carla

Source: Processes; Dec2024, Vol. 12 Issue 12, p2938, 23p

Subject Terms: BIOTECHNOLOGY, EXTRACELLULAR vesicles, DRUG stability, METABOLITES, CELL communication

Aloe Extracellular Vesicles as Carriers of Photoinducible Metabolites Exhibiting Cellular Phototoxicity.

Authors: Calzoni, Eleonora, Bertoldi, Agnese, Cesaretti, Alessio, Alabed, Husam B. R., Cerrotti, Giada, Pellegrino, Roberto Maria, Buratta, Sandra, Urbanelli, Lorena, Emiliani, Carla

Source: Cells (2073-4409); Nov2024, Vol. 13 Issue 22, p1845, 17p

Subject Terms: ALOE vera, INFLAMMATORY bowel diseases, EXTRACELLULAR vesicles, DRUG delivery systems, PHOTODYNAMIC therapy

LipidOne: user-friendly lipidomic data analysis tool for a deeper interpretation in a systems biology scenario

Authors: Pellegrino, Roberto Maria, Giulietti, Matteo, Alabed, Husam B R, Buratta, Sandra, Urbanelli, Lorena, Piva, Francesco, Emiliani, Carla

Source: Bioinformatics. 38(6):1767-1769

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147994756.0x000001&indx=1&recIds=ETOCvdc_100147994756.0x000001

Extracellular Vesicles in Aging: An Emerging Hallmark?

Authors: Manni, Giorgia¹ (AUTHOR), Buratta, Sandra² (AUTHOR), Pallotta, Maria Teresa¹ (AUTHOR) maria.pallotta@unipg.it, Chiasserini, Davide¹ (AUTHOR), Di Michele, Alessandro³ (AUTHOR), Emiliani, Carla^2,4 (AUTHOR), Giovagnoli, Stefano⁵ (AUTHOR), Pascucci, Luisa⁶ (AUTHOR), Romani, Rita¹ (AUTHOR), Bellezza, Ilaria¹ (AUTHOR) maria.pallotta@unipg.it, Urbanelli, Lorena² (AUTHOR) maria.pallotta@unipg.it, Fallarino, Francesca¹ (AUTHOR)

Source: Cells (2073-4409). Feb2023, Vol. 12 Issue 4, p527. 22p.

Subject Terms: *EXTRACELLULAR vesicles, *AGING, *BODY fluids, *AGING prevention, *ACTIVE aging, *PHENOTYPIC plasticity

Protein and Lipid Content of Milk Extracellular Vesicles: A Comparative Overview.

Authors: Buratta, Sandra¹ (AUTHOR), Urbanelli, Lorena¹ (AUTHOR), Tognoloni, Alessia² (AUTHOR), Latella, Raffaella¹ (AUTHOR), Cerrotti, Giada¹ (AUTHOR), Emiliani, Carla¹ (AUTHOR), Chiaradia, Elisabetta² (AUTHOR) elisabetta.chiaradia@unipg.it

Source: Life (2075-1729). Feb2023, Vol. 13 Issue 2, p401. 14p.

Subject Terms: *EXTRACELLULAR vesicles, *BREAST milk, *MILK, *COMPOSITION of milk, *MILK proteins, *ANIMAL species

Lipidomic analysis of cancer cells cultivated at acidic pH reveals phospholipid fatty acids remodelling associated with transcriptional reprogramming

Authors: Urbanelli, Lorena, Buratta, Sandra, Logozzi, Mariantonia, Mitro, Nico, Sagini, Krizia, Raimo, Rossella Di, Caruso, Donatella, Fais, Stefano, Emiliani, Carla

Source: Journal of enzyme inhibition and medicinal chemistry. 35(1):963-973

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123144101.0x000001&indx=1&recIds=ETOCvdc_100123144101.0x000001

LipidOne 2.0: A Web Tool for Discovering Biological Meanings Hidden in Lipidomic Data.

Authors: Alabed, Husam B. R., Mancini, Dorotea Frongia, Buratta, Sandra, Calzoni, Eleonora, Giacomo, Danika Di, Emiliani, Carla, Martino, Sabata, Urbanelli, Lorena, Pellegrino, Roberto Maria

Source: Current Protocols; Sep2024, Vol. 4 Issue 9, p1-19, 19p

Isolation of Extracellular Vesicles from Agri-Food Wastes: A Novel Perspective in the Valorization of Agri-Food Wastes and By-Products.

Authors: Latella, Raffaella, Calzoni, Eleonora, Urbanelli, Lorena, Cerrotti, Giada, Porcellati, Serena, Emiliani, Carla, Buratta, Sandra, Tancini, Brunella

Source: Foods; May2024, Vol. 13 Issue 10, p1492, 21p

Subject Terms: EXTRACELLULAR vesicles, AGRICULTURAL wastes, CELL communication, MANUFACTURING processes

Metabolic Profiling as an Approach to Differentiate T-Cell Acute Lymphoblastic Leukemia Cell Lines Belonging to the Same Genetic Subgroup.

Authors: Alabed, Husam B. R., Pellegrino, Roberto Maria, Buratta, Sandra, Lema Fernandez, Anair Graciela, La Starza, Roberta, Urbanelli, Lorena, Mecucci, Cristina, Emiliani, Carla, Gorello, Paolo

Source: International Journal of Molecular Sciences; Apr2024, Vol. 25 Issue 7, p3921, 19p

Subject Terms: LYMPHOBLASTIC leukemia, CELL lines, ACUTE leukemia, T cells, GENE expression

Effects of xylazine and dexmedetomidine on equine articular chondrocytes in vitro

Authors: Mancini, Francesco, Nannarone, Sara, Buratta, Sandra, Ferrara, Giuseppina, Stabile, Anna Maria, Vuerich, Matteo, Santinelli, Isabella, Pistilli, Alessandra, Chiaradia, Elisabetta

Source: In Veterinary Anaesthesia and Analgesia March 2017 44(2):295-308

Protective effects of platelet-rich plasma against lidocaine cytotoxicity on canine articular chondrocytes

Authors: Bianchini, Erika, Mancini, Francesco, Meo, Antonio, Stabile, Anna, Buratta, Sandra, Moscati, Livia, Pistilli, Alessandra, Floridi, Claudia, Pepe, Marco, Chiaradia, Elisabetta

Source: Acta veterinaria scandinavica. 60(1):1-7

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184384508.0x000001&indx=1&recIds=ETOCvdc_100184384508.0x000001

Characterization of Nanovesicles Isolated from Olive Vegetation Water.

Authors: Buratta, Sandra, Latella, Raffaella, Chiaradia, Elisabetta, Salzano, Anna Maria, Tancini, Brunella, Pellegrino, Roberto Maria, Urbanelli, Lorena, Cerrotti, Giada, Calzoni, Eleonora, Alabed, Husam B. R., De Pascale, Sabrina, Lugini, Luana, Federici, Cristina, Scaloni, Andrea, Emiliani, Carla

Source: Foods; Mar2024, Vol. 13 Issue 6, p835, 16p

Subject Terms: EXTRACELLULAR vesicles, AGRICULTURAL wastes, SCANNING electron microscopy, BIOMOLECULES, OLIVE oil

A role for the autophagy regulator Transcription Factor EB in amiodarone-induced phospholipidosis

Authors: Buratta, Sandra, Urbanelli, Lorena, Ferrara, Giuseppina, Sagini, Krizia, Goracci, Laura, Emiliani, Carla

Source: In Biochemical Pharmacology 1 June 2015 95(3):201-209

Evaluating the risk of phospholipidosis using a new multidisciplinary pipeline approach

Authors: Goracci, Laura, Buratta, Sandra, Urbanelli, Lorena, Ferrara, Giuseppina, Di Guida, Riccardo, Emiliani, Carla, Cross, Simon

Source: In European Journal of Medicinal Chemistry 6 March 2015 92:49-63

Synthesis and phospholipidosis effect of a series of cationic amphiphilic compounds: a case study to evaluate in silico and in vitro assays

Authors: Lepri, Susan, Valeri, Aurora, Buratta, Sandra, Ceccarelli, Martina, Bartolini, Desirée, Ruzziconi, Renzo, Goracci, Laura

Source: Medicinal chemistry research. 27(2):679-692

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118154404.0x000001&indx=1&recIds=ETOCvdc_100118154404.0x000001

Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells.

Authors: Buratta, Sandra¹ sandra.buratta@unipg.it, Shimanaka, Y.², Costanzi, E.¹, Ni, S.², Urbanelli, L.¹, Kono, N.², Morena, F.¹, Sagini, K.^1,3, Giovagnoli, S.⁴, Romani, R.⁵, Gargaro, M.⁵, Arai, H.^2,6, Emiliani, C.¹

Source: Scientific Reports. 2/25/2021, Vol. 11 Issue 1, p1-15. 15p.

Subject Terms: *MEMBRANE lipids, *VESICLES (Cytology), *LIVER cancer, *CANCER cells, *CELL communication