MHC class I loss in endometrial carcinoma: a potential resistance mechanism to immune checkpoint inhibition

Authors: Friedman, Lisa A., Bullock, Timothy N., Sloan, Emily A., Ring, Kari L., Mills, Anne M.

Source: In Modern Pathology March 2021 34(3):627-636

Differential T cell accumulation within intracranial and subcutaneous melanomas is associated with differences in intratumoral myeloid cells.

Authors: Stasiak, Katarzyna, Stevens, Aaron D., Bolte, Ashley C., Curley, Colleen T., Perusina Lanfranca, Mirna, Lindsay, Robin S., Eyo, Ukpong B., Lukens, John R., Price, Richard J., Bullock, Timothy N. J., Engelhard, Victor H.

Source: Cancer Immunology, Immunotherapy; Jan2025, Vol. 74 Issue 1, p1-17, 17p

Subject Terms: MYELOID cells, ANTIGEN presenting cells, T cells, TUMOR antigens, CELL populations

Ready for Prime Time? Dendritic Cells in High-Grade Gliomas.

Authors: Conarroe, Claire A.¹ (AUTHOR) kyj2gv@virginia.edu, Bullock, Timothy N. J.¹ (AUTHOR)

Source: Cancers. Jun2023, Vol. 15 Issue 11, p2902. 14p.

Subject Terms: *DENDRITIC cells, *GLIOMAS, *TREATMENT effectiveness, *T cells, *TUMOR antigens, *TUMOR grading, *IMMUNOTHERAPY

Modulation of NKG2D, NKp46, and Ly49C/I facilitates natural killer cell-mediated control of lung cancer

Authors: Shi, Lei, Li, Kang, Guo, Yizhan, Banerjee, Anirban, Wang, Qing, Lorenz, Ulrike M., Parlak, Mahmut, Sullivan, Lucy C., Onyema, Oscar Okwudiri, Arefanian, Saeed, Stelow, Edward B., Brautigan, David L., Bullock, Timothy N. J., Brown, Michael G., Krupnick, Alexander Sasha

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Nov . 115(46), 11808-11813.

Access URL: https://www.jstor.org/stable/26563789

IDO expression in breast cancer: an assessment of 281 primary and metastatic cases with comparison to PD-L1

Authors: Dill, Erik A., Dillon, Patrick M., Bullock, Timothy N., Mills, Anne M.

Source: In Modern Pathology January 2018 31(10):1513-1522

Tissue- and Temporal-Dependent Dynamics of Myeloablation in Response to Gemcitabine Chemotherapy.

Authors: Kitelinger, Lydia E., Thim, Eric A., Zipkowitz, Sarah Y., Price, Richard J., Bullock, Timothy N. J.

Source: Cells (2073-4409); Aug2024, Vol. 13 Issue 16, p1317, 22p

Subject Terms: MYELOID-derived suppressor cells, PROGNOSIS, TRIPLE-negative breast cancer, TUMOR microenvironment, CANCER invasiveness

Spatially resolved quantification of oxygen consumption rate in ex vivo lymph node slices.

Authors: Anbaei, Parastoo, Stevens, Marissa G., Ball, Alexander G., Bullock, Timothy N. J., Pompano, Rebecca R.

Source: Analyst; 5/7/2024, Vol. 149 Issue 9, p2609-2620, 12p

Subject Terms: OXYGEN consumption, LYMPH nodes, LYMPHOID tissue, OXYGEN detectors, OPTICAL measurements, CELL suspensions, TISSUE culture

The mitochondrial fission protein DRP1 influences memory CD8+ T cell formation and function.

Authors: Stevens, Marissa G, Mason, Frank M, Bullock, Timothy N J

Source: Journal of Leukocyte Biology; Apr2024, Vol. 115 Issue 4, p679-694, 16p

Subject Terms: MITOCHONDRIAL proteins, IMMUNOLOGIC memory, CELL physiology, T cell receptors, T cells

Fundamentals of Cancer Immunology and Their Application to Cancer Vaccines.

Authors: Bullock, Timothy N. J.¹ (AUTHOR) Tb5v@virginia.edu

Source: CTS: Clinical & Translational Science. Jan2021, Vol. 14 Issue 1, p120-131. 12p.

Subject Terms: *CANCER vaccines, *IMMUNOLOGY, *VACCINE development, *IMMUNE system, *IMMUNE response, *HUMAN papillomavirus vaccines, *VACCINES

IL-27 and the generation of CD8⁺ T-cell responses to peptide vaccines

Authors: Bullock, Timothy N. J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2014 Nov . 111(47), 16639-16640.

Access URL: https://www.jstor.org/stable/43279352

Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation.

Authors: Thim, Eric A., Kitelinger, Lydia E., Rivera-Escalera, Fátima, Mathew, Alexander S., Elliott, Michael R., Bullock, Timothy N. J., Price, Richard J.

Source: Theranostics; 2024, Vol. 14 Issue 4, p1647-1661, 15p

Phase I Study of Entinostat, Atezolizumab, Carboplatin, and Etoposide in Previously Untreated Extensive-Stage Small Cell Lung Cancer, ETCTN 10399.

Authors: Gentzler, Ryan D, Villaruz, Liza C, Rhee, John C, Horton, Bethany, Mock, Joseph, Hanley, Michael, Kim, Kyeongmin, Rudek, Michelle A, Phelps, Mitch A, Carducci, Michael A, Piekarz, Richard, Park, Kwon-Sik, Bullock, Timothy N, Rudin, Charles M

Source: Oncologist; Nov2023, Vol. 28 Issue 11, p1007-1007, 5p

Subject Terms: LUNG cancer, ETOPOSIDE, BIOLOGICAL models, CARBOPLATIN, CLINICAL trials, LUNG tumors, ANTINEOPLASTIC agents, MONOCLONAL antibodies, NEUTROPENIA, DESCRIPTIVE statistics, THROMBOCYTOPENIA, ADVERSE health care events, PATIENT safety

Self MHC class I–licensed NK cells enhance adaptive CD8 T-cell viral immunity

Authors: Stadnisky, Michael D., Xie, Xuefang, Coats, Ebony R., Bullock, Timothy N., Brown, Michael G.

Source: In Blood 12 May 2011 117(19):5133-5141

Profiling of the immune landscape in murine glioblastoma following blood brain/tumor barrier disruption with MR image-guided focused ultrasound.

Authors: Sheybani, Natasha D., Witter, Alexandra R., Garrison, William J., Miller, G. Wilson, Price, Richard J., Bullock, Timothy N. J.

Source: Journal of Neuro-Oncology; Jan2022, Vol. 156 Issue 1, p109-122, 14p

Therapeutic vaccination targeting CD40 and TLR3 controls melanoma growth through existing intratumoral CD8 T cells without new T cell infiltration.

Authors: Stevens, Aaron D.¹ (AUTHOR), Bullock, Timothy N. J.¹ (AUTHOR) tb5v@virginia.edu

Source: Cancer Immunology, Immunotherapy. Aug2021, Vol. 70 Issue 8, p2139-2150. 12p.

Subject Terms: *T cells, *VACCINE effectiveness, *MELANOMA, *TUMOR antigens, *DENDRITIC cells

MHC Class I Loss in Triple-negative Breast Cancer: A Potential Barrier to PD-1/PD-L1 Checkpoint Inhibitors.

Authors: Dusenbery, Anna C., Maniaci, Joseph L., Hillerson, Natalie D., Dill, Erik A., Bullock, Timothy N., Mills, Anne M.

Source: American Journal of Surgical Pathology; May2021, Vol. 45 Issue 5, p701-707, 7p

Results of an early safety analysis of a study of the combination of pembrolizumab and pelvic chemoradiation in locally advanced cervical cancer.

Authors: Duska, Linda R., Scalici, Jennifer M., Temkin, Sarah M., Schwarz, Julie K., Crane, Erin K., Moxley, Katherine M., Hamilton, Chad A., Wethington, Stephanie L., Petroni, Gina R., Varhegyi, Nikole E., Clift, Sheena H., Bullock, Timothy N. J., Showalter, Timothy N.

Source: Cancer (0008543X); Nov2020, Vol. 126 Issue 22, p4948-4956, 9p

Subject Terms: IMMUNE checkpoint inhibitors, CERVICAL cancer, CHEMORADIOTHERAPY, APOPTOSIS

Company/Entity: INTERNATIONAL Baccalaureate Organization

Modulation of PKM activity affects the differentiation of TH17 cells.

Authors: Seki, Scott M., Posyniak, Kacper, McCloud, Rebecca, Rosen, Dorian A., Fernández-Castañeda, Anthony, Beiter, Rebecca M., Serbulea, Vlad, Nanziri, Sarah C., Hayes, Nikolas, Spivey, Charles, Gemta, Lelisa, Bullock, Timothy N. J., Hsu, Ku-Lung, Gaultier, Alban

Source: Science Signaling; 10/27/2020, Vol. 13 Issue 655, p1-13, 13p

Subject Terms: SUPPRESSOR cells, CELL differentiation, PATHOLOGY, CELL physiology, T cells, GRANULOCYTE-macrophage colony-stimulating factor, GLYCOLYSIS

Loss of MHC Class I Expression in HPV-associated Cervical and Vulvar Neoplasia: A Potential Mechanism of Resistance to Checkpoint Inhibition.

Authors: Dibbern, Megan E., Bullock, Timothy N., Jenkins, Taylor M., Duska, Linda R., Stoler, Mark H., Mills, Anne M.

Source: American Journal of Surgical Pathology; Sep2020, Vol. 44 Issue 9, p1184-1191, 8p

This result is not displayed to guests.
Login for full access.