Challenges and Strategies to Combat Resistance Mechanisms in Thyroid Cancer Therapeutics

Authors: Gild, Matti L., Bullock, Martyn, Tsang, Venessa, Clifton-Bligh, Roderick J., Robinson, Bruce G., Wirth, Lori J.

Source: Thyroid. 33(6):682-690

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185121042.0x000001&indx=1&recIds=ETOCvdc_100185121042.0x000001

A Case Report of Poor Response to Selpercatinib in the Presence of a 632_633 RET Deletion

Authors: Wijewardene, Ayanthi, Bastard, Karine, Wang, Bin, Gild, Matti, Luxford, Catherine, Gill, Anthony, Robinson, Bruce, Bullock, Martyn, Clifton-Bligh, Roderick

Source: Thyroid. 33(1):119-125

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176154684.0x000001&indx=1&recIds=ETOCvdc_100176154684.0x000001

Evaluating the prognostic potential of circulating cell-free DNA in advanced thyroid cancer.

Authors: Wijewardene, Ayanthi, Clifton-Bligh, Roderick J., Bin Wang, Luxford, Catherine, Robinson, Bruce G., Bullock, Martyn, Gild, Matti

Source: Endocrine-Related Cancer; Feb2025, Vol. 32 Issue 2, p55-64, 10p

Subject Terms: NUCLEOTIDE sequencing, ANAPLASTIC thyroid cancer, MEDULLARY thyroid carcinoma, CELL-free DNA, CANCER patients

The orphan nuclear receptor Nr4a1 contributes to interstitial cardiac fibrosis via modulation of cardiac fibroblast and macrophage phenotype.

Authors: Widiapradja, Alexander, Connery, Heather, Bullock, Martyn, Kasparian, Ainsley O., Clifton-Bligh, Roderick, Levick, Scott P.

Source: Cellular & Molecular Life Sciences; 12/7/2024, Vol. 81 Issue 1, p1-18, 18p

Subject Terms: EXTRACELLULAR matrix proteins, HEART fibrosis, MEDICAL sciences, ANGIOTENSIN II, MYOCARDIAL ischemia

Congenital Hypoparathyroidism Associated With Elevated Circulating Nonfunctional Parathyroid Hormone Due to Novel PTH Mutation

Authors: Gild, Matti L, Bullock, Martyn, Luxford, Catherine, Field, Michael, Clifton-Bligh, Roderick J

Source: Journal of clinical endocrinology & metabolism. 105(7):2408-2412

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108983259.0x000001&indx=1&recIds=ETOCvdc_100108983259.0x000001

The Association between Lymphocytic Thyroiditis and Papillary Thyroid Cancer Harboring Mutant BRAF: A Systematic Review and Meta-Analysis.

Authors: Perampalam, Sumathy, Wu, Katherine, Gild, Matti, Tacon, Lyndal, Bullock, Martyn, Clifton-Bligh, Roderick

Source: Thyroid; Sep2024, Vol. 34 Issue 9, p1082-1093, 12p

Subject Terms: AUTOIMMUNE thyroiditis, BRAF genes, ODDS ratio, PROGNOSIS, CONFIDENCE intervals, THYROID cancer, THYROIDITIS

Pyrimidine-Dependent UV-Mediated Cross-Linking Magnifies Minor Genetic or Epigenetic Changes in Clinical Samples.

Authors: Yu, Fangyan, Ahmed, Farzana, Smilkou, Stavroula, Yasmin-Karim, Sayeda, Darbeheshti, Farzaneh, Markou, Athina, Bullock, Martyn, Boukovinas, Ioannis, Adalsteinsson, Viktor A, Lianidou, Evi, Makrigiorgos, G Mike

Source: Clinical Chemistry; Sep2024, Vol. 70 Issue 9, p1151-1161, 11p

ETS Factor ETV5 Activates the Mutant Telomerase Reverse Transcriptase Promoter in Thyroid Cancer

Authors: Bullock, Martyn, Lim, Grace, Zhu, Ying, Åberg, Helena, Kurdyukov, Sergey, Clifton-Bligh, Roderick

Source: Thyroid. 29(11):1623-1633

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100092739695.0x000001&indx=1&recIds=ETOCvdc_100092739695.0x000001

Foxe1 Deletion in the Adult Mouse Is Associated With Increased Thyroidal Mast Cells and Hypothyroidism

Authors: Lim, Grace, Widiapradja, Alexander, Levick, Scott P, McKelvey, Kelly J, Liao, Xiao-Hui, Refetoff, Samuel, Bullock, Martyn, Clifton-Bligh, Roderick J

Source: Endocrinology. 163(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164805082.0x000001&indx=1&recIds=ETOCvdc_100164805082.0x000001

NRASQ61R Mutation-specific Immunohistochemistry Also Identifies the HRASQ61R Mutation in Medullary Thyroid Cancer and May Have a Role in Triaging Genetic Testing for MEN2

Authors: Reagh, Jessica, Bullock, Martyn, Andrici, Juliana, Turchini, John, Sioson, Loretta, Clarkson, Adele, Watson, Nicole, Sheen, Amy, Lim, Grace, Delbridge, Leigh, Sidhu, Stan, Sywak, Mark, Aniss, Ahmad, Shepherd, Phillip, Ng, Daniel, Oei, Paul, Field, Michael, Learoyd, Diana, Robinson, Bruce G., Clifton-Bligh, Roderick J., Gill, Anthony J.

Source: American journal of surgical pathology. 41(1):75-81

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100042283639.0x000001&indx=1&recIds=ETOCvdc_100042283639.0x000001

Real world experience of BRAFV600E mutation specific immunohistochemistry in colorectal carcinoma

Authors: Reagh, Jessica, Clarkson, Adele, Bullock, Martyn, Shepherd, Phillip, Gill, Anthony J.

Source: Pathology. 50(3):342-344

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135312553.0x000001&indx=1&recIds=ETOCvdc_100135312553.0x000001

BRAF V600E mutation is associated with an increased risk of nodal recurrence requiring reoperative surgery in patients with papillary thyroid cancer

Authors: O’Neill, Christine J., Bullock, Martyn, Chou, Angela, Sidhu, Stan B., Delbridge, Leigh W., Robinson, Bruce G., Gill, Anthony J., Learoyd, Diana L., Clifton-Bligh, Roderick, Sywak, Mark S.

Source: In Surgery 2010 148(6):1139-1146

The length of FOXE1 polyalanine tract in congenital hypothyroidism: Evidence for a pathogenic role from familial, molecular and cohort studies.

Authors: Grassi, Elisa Stellaria, Rurale, Giuditta, de Filippis, Tiziana, Gentilini, Davide, Carbone, Erika, Coscia, Francesca, Uraghi, Sarah, Bullock, Martyn, Clifton-Bligh, Roderick J., Gupta, Abhinav K., Persani, Luca

Source: Frontiers in Endocrinology; 3/16/2023, Vol. 14, p1-11, 11p

Subject Terms: CONGENITAL hypothyroidism, HYPOVENTILATION, GENETIC variation, FORKHEAD transcription factors, NUCLEOTIDE sequencing, TRANSCRIPTION factors, COHORT analysis

Polypharmacy With High Drug Burden Index (DBI) Alters the Gut Microbiome Overriding Aging Effects and Is Reversible With Deprescribing.

Authors: Gemikonakli, Gizem, Mach, John, Zhang, Fan, Bullock, Martyn, Tran, Trang, El-Omar, Emad, Hilmer, Sarah N

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences; Feb2023, Vol. 78 Issue 2, p213-222, 10p

Subject Terms: GUT microbiome, DEPRESCRIBING, POLYPHARMACY, FISHER discriminant analysis, AGING

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Response to Szymczak et al. re: "A Case Report of Poor Response to Selpercatinib in the Presence of a 632_633 RET Deletion".

Authors: Wijewardene, Ayanthi, Bastard, Karine, Wang, Bin, Gild, Matti, Luxford, Catherine, Gill, Anthony, Robinson, Bruce, Bullock, Martyn, Clifton-Bligh, Roderick

Source: Thyroid; Dec2023, Vol. 33 Issue 12, p1496-1497, 2p

Subject Terms: MEDULLARY thyroid carcinoma, GENETIC mutation

Key MicroRNA's and Their Targetome in Adrenocortical Cancer.

Authors: Chehade, Marthe^1,2 (AUTHOR) mche2952@uni.sydney.edu.au, Bullock, Martyn^1,2 (AUTHOR) martyn.bullock@sydney.edu.au, Glover, Anthony^1,2,3 (AUTHOR) anthony.glover@sydney.edu.au, Hutvagner, Gyorgy⁴ (AUTHOR) gyorgy.hutvagner@uts.edu.au, Sidhu, Stan^1,2,3 (AUTHOR) gyorgy.hutvagner@uts.edu.au

Source: Cancers. Aug2020, Vol. 12 Issue 8, p2198-2198. 1p.

Subject Terms: *ADRENAL tumors, *BIOMARKERS, *GENE expression, *MESSENGER RNA, *PHENOTYPES, *MICRORNA, *NEOPLASTIC cell transformation

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